Puffiness and fluid retention resulting from thyroid hypofunction, either organic (serious, and often complicated by pituitary or adrenalcortical deficiencies) or functional (often a bipolar depressive thyroid phase).
Having deficient thyroid levels, either from overt thyroid disease like myxedema, a generally low metabolism from functional causes, or subsequent to emotional depression or the use of depressant drugs.... hypothyroid
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