Najja Health Dictionary

a rare genetic disease in which the liver enzyme glucuronyl transferase, responsible for dealing with bilirubin, is absent. A large amount of unconjugated bilirubin accumulates in the blood leading to refractory jaundice in early childhood. The definitive treatment is a liver transplant; if left untreated, life expectancy is usually less than two years. [J. F. Crigler and V. A. Najjar (20th century), US paediatricians]... crigler–najjar syndrome