Bitter orange (Citrus aurantium).Plant Part Used: Leaf, fruit.Dominican Medicinal Uses: Leaves: decoction, orally, common cold, flu, headache; poultice or salve, externally, for headache, sinusitis. Fruit: juice, decoction, for diarrhea.Safety: Considered safe if used appropriately.Clinical Data: Human clinical trial: antifungal (essential oil).Laboratory & Preclinical Data: In vitro: antioxidant (constituent), insecticidal (fruit peel extract), relaxant (essential oil).* See entry for Naranja agria in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.