Neural spine Health Dictionary

Neural Spine: From 1 Different Sources


Neural Tube

The structure in the EMBRYO from which the BRAIN and SPINAL CORD develop.... neural tube

Neural Tube Defects

Congenital abnormalities resulting from the failure of the NEURAL TUBE to form normally. The resulting conditions include SPINA BIFIDA, MENINGOCELE and defects in the bones of the SKULL.... neural tube defects

Bamboo Spine

See: ANKYLOSING SPONDYLITIS. ... bamboo spine

Spine

The column of bones and cartilage that extends from the base of the skull to the pelvis, enclosing the spinal cord and supporting the trunk and head. The spine is made up of 33 roughly cylindrical vertebrae. Each pair of adjacent vertebrae is connected by a facet joint, which stabilizes the vertebral column. Between each pair of vertebrae lies a disc-shaped pad of cartilage called an intervertebral disc (see disc, intervertebral). These discs cushion the vertebrae during movement. The vertebrae are bound together by 2 ligaments running the length of the spine and by smaller ligaments between each vertebra. Attached to the vertebrae are several groups of muscles, which control movement of, and help to support, the spine. spine, disorders of Many disorders of the spine cause back pain. Spina bifida is a congenital disorder in which part of the spinal cord is exposed. Sometimes, the spine is abnormally curved (see lordosis, kyphosis, scoliosis). In ankylosing spondylitis, and in some cases of rheumatoid arthritis, spinal joints are affected; osteoarthritis affects the spinal joints of most people over 60. Other disorders affecting the spine are spinal injuries; disc prolapse, and spondylolisthesis.... spine

Spine And Spinal Cord, Diseases And Injuries Of

Scoliosis A condition where the spine is curved to one side (the spine is normally straight when seen from behind). The deformity may be mobile and reversible, or ?xed; if ?xed it is accompanied by vertebral rotation and does not disappear with changes in posture. Fixed scoliosis is idiopathic (of unknown cause) in 65–80 per cent of cases. There are three main types: the infantile type occurs in boys under three and in 90 per cent of cases resolves spontaneously; the juvenile type affects 4–9 year olds and tends to be progressive. The most common type is adolescent idiopathic scoliosis; girls are affected in 90 per cent of cases and the incidence is 4 per cent. Treatment may be conservative with a ?xed brace, or surgical fusion may be needed if the curve is greater than 45 degrees. Scoliosis can occur as a congenital condition and in neuromuscular diseases where there is muscle imbalance, such as in FRIEDREICH’S ATAXIA.

Kyphosis is a backward curvature of the spine causing a hump back. It may be postural and reversible in obese people and tall adolescent girls who stoop, but it may also be ?xed. Scheuermann’s disease is the term applied to adolescent kyphosis. It is more common in girls. Senile kyphosis occurs in elderly people who probably have osteoporosis (bone weakening) and vertebral collapse.

Disc degeneration is a normal consequence of AGEING. The disc loses its resiliance and becomes unable to withstand pressure. Rupture (prolapse) of the disc may occur with physical stress. The disc between the fourth and ?fth lumbar vertebrae is most commonly involved. The jelly-like central nucleus pulposus is usually pushed out backwards, forcing the annulus ?brosus to put pressure on the nerves as they leave the spinal canal. (See PROLAPSED INTERVERTEBRAL DISC.)

Ankylosing spondylitis is an arthritic disorder of the spine in young adults, mostly men. It is a familial condition which starts with lumbar pain and sti?ness which progresses to involve the whole spine. The discs and ligaments are replaced by ?brous tissue, making the spine rigid. Treatment is physiotherapy and anti-in?ammatory drugs to try to keep the spine supple for as long as possible.

A National Association for Ankylosing Spondylitis has been formed which is open to those with the disease, their families, friends and doctors.

Spondylosis is a term which covers disc degeneration and joint degeneration in the back. OSTEOARTHRITIS is usually implicated. Pain is commonly felt in the neck and lumbar regions and in these areas the joints may become unstable. This may put pressure on the nerves leaving the spinal canal, and in the lumbar region, pain is generally felt in the distribution of the sciatic nerve – down the back of the leg. In the neck the pain may be felt down the arm. Treatment is physiotherapy; often a neck collar or lumbar support helps. Rarely surgery is needed to remove the pressure from the nerves.

Spondylolisthesis means that the spine is shifted forward. This is nearly always in the lower lumbar region and may be familial, or due to degeneration in the joints. Pressure may be put on the cauda equina. The usual complaint is of pain after exercise. Treatment is bed rest in a bad attack with surgery indicated only if there are worrying signs of cord compression.

Spinal stenosis is due to a narrowing of the spinal canal which means that the nerves become squashed together. This causes numbness with pins and needles (paraesthia) in the legs. COMPUTED TOMOGRAPHY and nuclear magnetic resonance imaging scans can show the amount of cord compression. If improving posture does not help, surgical decompression may be needed.

Whiplash injuries occur to the neck, usually as the result of a car accident when the head and neck are thrown backwards and then forwards rapidly. This causes pain and sti?ness in the neck; the arm and shoulder may feel numb. Often a support collar relieves the pain but recovery commonly takes between 18 months to three years.

Transection of the cord occurs usually as a result of trauma when the vertebral column protecting the spinal cord is fractured and becomes unstable. The cord may be concussed or it may have become sheared by the trauma and not recover (transected). Spinal concussion usually recovers after 12 hours. If the cord is transected the patient remains paralysed. (See PARALYSIS.)... spine and spinal cord, diseases and injuries of

Neural Arch

see vertebra.... neural arch

Neural Crest

the two bands of ectodermal tissue that flank the *neural plate of the early embryo. Cells of the neural crest migrate throughout the embryo and develop into sensory nerve cells and peripheral nerve cells of the autonomic nervous system.... neural crest

Neural Plate

the strip of ectoderm lying along the central axis of the early embryo that forms the *neural tube and subsequently the central nervous system.... neural plate

Neural Tube Defect

A developmental failure affecting the spinal cord or brain of the embryo. The most serious defect is anencephaly (total lack of a brain), which is fatal. More common is spina bifida, in which the vertebrae do not form a complete ring around the spinal cord. Spina bifida can occur anywhere on the spine, but it is most common in the lower back.

There are different forms of spina bifida. In spina bifida occulta, the only defect is a failure of the fusion of the bony arches behind the spinal cord, which may not cause any problems. When the bone defect is more extensive, there may be a meningocele, a protrusion of the meninges, or a myelomeningocele, a malformation of the spinal cord. Myelomeningocele is likely to cause severe handicap, with paralysis of the legs, loss of sensation in the lower body, hydrocephalus, and paralysis of the anus and bladder, causing incontinence. Associated problems include cerebral palsy, epilepsy, and mental handicap.

Surgery is usually performed a few days after birth. In mild cases, the defect can usually be corrected, but in myelomeningocele, some handicap will remain.

Genetic factors play a part in neural tube defects, which show multifactorial inheritance. Couples who have had an affected child or who have a family history of neural tube defects should seek genetic counselling. The risk of a neural tube defect occurring can be substantially reduced if the mother takes folic acid supplements for a month before conception and during the early part of the pregnancy.

Ultrasound scanning and amniocentesis allow accurate antenatal testing for neural tube defects.... neural tube defect




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