A molecule that is formed from a structural protein that is combined with nucleic acid, and generally found in cell nuclei and other proliferative points in cells. Upon cell death, nucleoproteins, unlike others, cannot be catabolized and recycled efficiently; instead, part of the protein is degraded to purines, and thence to uric acid. Uric acid, unlike urea, is an excretory dead end.
n. a compound that occurs in cells and consists of nucleic acid and protein tightly bound together. *Ribosomes are nucleoproteins containing RNA; *chromosomes are nucleoproteins containing DNA.
Linn.
Family: Papilionaceae; Fabaceae.
Habitat: Throughout India in tropical areas; also cultivated in hedges.
English: Butterfly Pea, Winged- leaved Clitoria, Mezereon.
Ayurvedic: Girikarnikaa, Aparaa- jitaa, Aasphota, Girimallikaa, Girikanyaa, Kokilaa,Yonipushpaa, Vishnukraantaa. (Evolvulus alsi- noides Linn. is also known as Vishnukraantaa, Vishnukranti). Used as Shankhapushpi in the South.
Unani: Mezereon Hindi.
Siddha/Tamil: Kakkanam.
Folk: Koyal (Punjab).
Action: Root—cathartic like jalap. Roots cause gripe and tenesmus, hence not recommended as purgative. Used in ascites. Root bark—diuretic (infusion used in irritation of bladder and urethra). Root juice—given in cold milk to liquefy phlegm in chronic bronchitis. The root, bark, seeds and leaves—used for gastric acidity. The root is administered with honey as a general tonic to children for improving mental faculty.
The Ayurvedic Pharmacopoeia of India recommends the dried leaf in migraine, psychoneurosis and mania.An alcoholic extract of the plant showed sedative and hypothermic effect in rodents.Rats, fed with ethanol extract of flowers, showed a significantly lowered serum sugar level in experimentally induced diabetes.The seeds contain a nucleoprotein with its amino acid sequence similar to insulin, but for the absence of his- tidine, threonine, proline and crystine.Seeds gave cinnamic acid, flavonol gly- coside. Leaves contain glycosides of kaempferol.In South India, the seeds and roots constitute the drug Shankhapushpi, used as a nervine tonic. In other regions, Canscora decussata, Convolvulus pluricaulis, Evolvulus alsinoides and Lavendula bipinnata are used as Shan- khapushpi.
Dosage: Root—1-3 g powder (API Vol. II); dried leaf—2-5 g; seed—1- 3 g. (API Vol. IV.)... clitoria ternatea
These are waste products or metabolites of nucleoproteins. They are not recyclable and are broken down further to the primary excretable form, uric acid. High purine presence in a tissue signifies a recent high turnover in nucleoproteins from injury or cell death, which is why some purines, such as allantoin, will stimulate cell regeneration. Many plants contain allantoin, most noticeably Comfrey. Some foods are heavy purine producers and can elevate serum uric acid levels. These include organ meats, seafood, legumes, and such politically correct foods as spirulina, chlorella, and bee pollen. Caffeine and theobromine are purine-based alkaloids and can mildly increase uric acid, but they pale beside algae, pollen, and glandular extracts from the chiropractor.... purines
The final end product of certain native or dietary proteins, especially the nucleoproteins found in the nucleus of cells. Unlike the much smaller nitrogenous waste product urea, which is mostly recycled to form many amino acids, uric acid is an unrecyclable metabolite. It is a bent nail that won’t restraighten, and it must be excreted: nucleoprotein to purine to uric acid to the outside in the urine or the sweat. (See GOUT, PURINES.)... uric acid
Health Encyclopedia