a pregnancy-related condition characterized by intense *pruritus (itch) – and consequent sleep deprivation – in the absence of a skin rash, with abnormal liver function tests and elevated bile acids, all of which remit following delivery. The clinical importance of obstetric cholestasis lies in the potential fetal risks, which may include prematurity and intrauterine death.
A reduction or stoppage in the ?ow of BILE into the intestine caused either by a blockage such as a stone in the BILE DUCT or by liver disease disturbing the production of bile. The ?rst type is called extrahepatic biliary obstruction and the second, intrahepatic cholestasis. The patient develops jaundice and itching and passes dark urine and pale faeces. Cholestasis may occasionally occur during pregnancy.... cholestasis
(OASIS) a spectrum of injuries that encompasses both third- and fourth-degree *perineal tears. Injury to the anal sphincter mechanism during childbirth may arise secondarily to direct disruption of the sphincter muscles and/or traction of the pudendal nerves. Disruption of the anal sphincter muscles is best assessed by anal ultrasound examination. This is usually performed using a high-frequency (10 MHz) endoanal probe. In selected cases with complex injury and/or suspected rectovaginal *fistula, magnetic resonance imaging (MRI) may also be employed.... obstetric anal sphincter injury
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