Organ of corti Health Dictionary

Organ Of Corti: From 1 Different Sources


(spiral organ) the sense organ of the *cochlea of the inner ear, which converts sound signals into nerve impulses that are transmitted to the brain via the cochlear nerve. [A. Corti (1822–88), Italian anatomist]
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Cortisone

An early corticosteroid drug (see CORTICOSTEROIDS), now obsolete and replaced by PREDNISOLONE and HYDROCORTISONE.... cortisone

Corticosteroids

Natural steroid hormones or synthetic analogues, usually taken for suppressing inflammation (and immunity) and therefore having cortisone-like functions, or taken as analogues to adrenocortical androgen...or even testosterone, in order to impress the other gym members, make varsity by your junior year or to join the WWF and get newbie-mangled for two years by The Hangman or even the Hulkster Himself. Then, if your gonads don’t fall off and your back holds up you get promoted to Good Guy, have your chance to Take A Name and finally wear your chosen costume...a spandex violet nurse’s uniform.... corticosteroids

Cortisol

Another name for HYDROCORTISONE.... cortisol

Organ

A collection of di?erent tissues that form a distinct structure in the body with a particular function or functions. The LIVER, for example, comprises a collection of di?erent metabolic cells bound together with connective tissue and liberally supplied with blood vessels; it performs vital functions in the breakdown of substances absorbed from the gastrointestinal tract. Other examples of organs are the KIDNEYS, BRAIN and HEART. (See also TRANSPLANTATION.)... organ

Corticotropin

Corticotropin is the British Pharmacopoeia name for the adrenocorticotrophic hormone of the PITUITARY GLAND, also known as ACTH. It is so-called because it stimulates the functions of the cortex of the suprarenal glands. This results, among other things, in an increased output of cortisone.... corticotropin

End Organ

A structure at the end of a peripheral nerve that acts as receptor for a sensation. For example, the olfactory nerves have end organs that identify smells.... end organ

Target Organ

The speci?c organ (or tissue) at which a hormone (see HORMONES), drug or other agent is aimed to bring about its physiological or pharmacological e?ect.... target organ

Organ Transplantation

See TRANSPLANTATION.... organ transplantation

Corticosteroid Drugs

A group of drugs that are similar to the corticosteroid hormones produced by the adrenal glands. Corticosteroids are used as hormone replacement therapy in Addison’s disease and when the adrenal glands or pituitary gland have been destroyed or removed. They are also used to treat inflammatory intestinal disorders such as ulcerative colitis and Crohn’s disease and as an urgent treatment for inflammation in the artery supplying the retina in temporal arteritis. Other uses include treatment of autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis, and treatment of asthma, eczema, and allergic rhinitis. Corticosteroid drugs are also used to prevent organ rejection after transplant surgery and in the treatment of some types of cancer, such as a lymphoma or leukaemia. Corticosteroid injections may relieve pain in disorders such as tennis elbow and arthritis.

Side effects are uncommon when corticosteroids are given as a cream or by inhaler, but tablets taken in high doses for long periods may cause oedema, hypertension, diabetes mellitus, peptic ulcer, Cushing’s syndrome, inhibited growth in children, and, in rare cases, cataract or psychosis. High doses also impair the body’s immune system. Long-term treatment suppresses production of corticosteroid hormones by the adrenal glands, and sudden withdrawal may lead to adrenal failure.... corticosteroid drugs

Corticosteroid Hormones

A group of hormones produced by the adrenal glands that control the body’s use of nutrients and the excretion of salts and water in the urine.... corticosteroid hormones

Organ Donation

The agreement of a person (or his or her family) to surgical removal of one or more organs for use in transplant surgery.

Most organs for transplantation, such as the heart, lungs, liver, and kidneys, are removed immediately after death, often in intensive care units where heart and lung function is sometimes maintained by machine after brain death been certified.

Compatible living donors may also be able to give a kidney (see tissue-typing).

People can facilitate use of their organs after death by informing relatives and carrying a donor card.

(See also corneal graft; heart–lung transplant; heart transplant; heart-valve surgery; kidney transplant; liver transplant.)... organ donation

Cortical Evoked Response Audiometry

(CERA) an objective test of hearing that measures the electrical activity in the *cerebral cortex following sound stimulation.... cortical evoked response audiometry

Cortical Lewy Body Disease

a disorder characterized by a combination of *parkinsonism and *dementia, which typically fluctuates. Visual hallucinations are common, and there is exquisite sensitivity to phenothiazine drugs. Abnormal proteins called Lewy bodies are found within the nerve cells of the cortex and the basal ganglia. It is the third most common cause of dementia (dementia with Lewy bodies) after *Alzheimer’s disease and vascular dementia.... cortical lewy body disease

Corticosteroid

(corticoid) n. any steroid hormone synthesized by the adrenal cortex. There are two main groups of corticosteroids. The glucocorticoids (e.g. *cortisol, *cortisone, and corticosterone) are essential for the utilization of carbohydrate, fat, and protein by the body and for a normal response to stress. Naturally occurring and synthetic glucocorticoids have very powerful anti-inflammatory effects and are used to treat conditions that involve inflammation. The mineralocorticoids (e.g. *aldosterone) are necessary for the regulation of salt and water balance.... corticosteroid

Corticosterone

n. a steroid hormone (see corticosteroid) synthesized and released in small amounts by the adrenal cortex.... corticosterone

Corticotrophin

n. see ACTH.... corticotrophin

Corticotrophin-releasing Hormone

(CRH) a peptide hypothalamic hormone (of 41 amino acids) stimulating the release of *ACTH (adrenocorticotrophic hormone) from the anterior pituitary. Its own release is suppressed by a *negative feedback loop involving cortisol, and its action is increased by antidiuretic hormone (see vasopressin) and *angiotensin II. It can be administered intravenously as part of the CRH test, during which blood is analysed at 15-minute intervals for one hour for the ACTH response, which is excessive in cases of primary adrenal failure and suppressed in cases of anterior *hypopituitarism.... corticotrophin-releasing hormone

Golgi Tendon Organ

see tendon organ.... golgi tendon organ

Multi-organ Failure

(MOF) see multiple organ dysfunction syndrome.... multi-organ failure

Multiple Organ Dysfunction Syndrome

(MODS, multi-organ failure, multiple organ failure, MOF) a common cause of death following severe injury, overwhelming infection, or immune deficiency states.... multiple organ dysfunction syndrome

Organ Of Jacobson

(vomeronasal organ) a small blind sac in the wall of the nasal cavity. In humans it never develops properly and has no function, but in lower animals (e.g. snakes) it is one of the major organs of olfaction. [L. L. Jacobson (1783–1843), Danish anatomist]... organ of jacobson

Sense Organ

a collection of specialized cells (*receptors), connected to the nervous system, that is capable of responding to a particular stimulus from either outside or inside the body. Sense organs can detect light (the eyes), heat, pain, and touch (the skin), smell (the nose), and taste (the taste buds).... sense organ

Spiral Organ

see organ of Corti.... spiral organ

Tendon Organ

(Golgi tendon organ) a sensory *receptor found within a tendon that responds to the tension or stretching of the tendon and relays impulses to the central nervous system. Like stretch receptors in muscle, tendon organs are part of the *proprioceptor system.... tendon organ



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