Any generalized bone defect due to metabolic disorders.
Types of osteodystrophy include rickets; osteomalacia; osteoporosis due to Cushing’s syndrome or excessive intake of corticosteroid drugs; and bone cysts and bone mass reduction associated with chronic kidney failure or hyperparathyroidism.
In adults, an osteodystrophy is usually reversible if the underlying cause is treated before bone deformity occurs.
n. any generalized bone disease resulting from a metabolic disorder. In renal osteodystrophy chronic kidney failure leads to diffuse bone changes resulting from a number of factors, including osteomalacia, secondary *hyperparathyroidism stimulated by hypocalcaemia and hyperphosphataemia, acidosis from the renal failure, and metastatic calcification related to high levels of calcium and phosphate in the blood. See also Albright’s hereditary osteodystrophy.
the skeletal abnormalities, collectively, of *pseudohypoparathyroidism. These include short stature, abnormally short fingers and toes (particularly involving the fourth and fifth metacarpals and metatarsals), and soft-tissue calcification. [F. Albright (1900–69), US physician]... albright’s hereditary osteodystrophy
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