Measles, formerly known as morbilli, is an acute infectious disease occurring mostly in children and caused by an RNA paramyxovirus.
Epidemiology There has been a dramatic fall in the number of sufferers from 1986, when more than 80,000 cases were reported. This is due to the introduction in 1988 of the measles, mumps and rubella vaccine (MMR VACCINE – see also IMMUNISATION); 1990, when the proportion of children immunised reached 90 per cent, was the ?rst year in which no deaths from measles were reported. Even so, fears of side-effects of the vaccine against measles – including scienti?cally unproven and discredited claims of a link with AUTISM – mean that some children in the UK are not being immunised, and since 2002 local outbreaks of measles have been reported in a few areas of the UK. Side-effects are, however, rare and the government is campaigning to raise the rate of immunisation, with GPs being set targets for their practices.
There are few diseases as infectious as measles, and its rapid spread in epidemics is no doubt due to the fact that this viral infection is most potent in the earlier stages. Hence the dif?culty of timely isolation, and the readiness with which the disease is spread, which is mostly by infected droplets. In developing countries measles results in the death of more than a million children annually.
Symptoms The incubation period, during which the child is well, lasts 7–21 days. Initial symptoms are CATARRH, conjunctivitis (see EYE, DISORDERS OF), fever and a feeling of wretchedness. Then Koplik spots – a classic sign of measles – appear on the roof of the mouth and lining of the cheeks. The macular body rash, typical of measles, appears 3–5 days later. Common complications include otitis media (see under EAR, DISEASES OF) and PNEUMONIA. Measles ENCEPHALITIS can cause permanent brain damage. A rare event is a gradual dementing disease (see DEMENTIA) called subacute sclerosing panenecephalitis (SSPE).
Treatment Isolation of the patient and treatment of any secondary bacterial infection, such as pneumonia or otitis, with antibiotics. Children usually run a high temperature which can be relieved with cool sponging and antipyretic drugs. Calamine lotion may alleviate any itching.... measles
An acute infectious disease, caused by a paramyxovirus, and most common in children. Although it usually infects the parotid glands, and is often only a mild condition, it CAN spread to the testes or ovaries, particularly when contracted by unresistant adults, and a mild child’s infection that is not properly honored by R&R always holds the potential for pancreatic or meningeal complications.... mumps
These are included in the paramyxoviruses (see MYXOVIRUSES) and divided into four types, all of which cause infection of the respiratory system (see RESPIRATION). Infection with type 3 begins in May, reaches a maximum in July or August and returns to base-line level in October. Types 1 and 2 are predominantly winter viruses. Children are commonly affected and the manifestations include CROUP, fever, and a rash.... parainfluenza viruses
n. one of a group of RNA-containing viruses that are associated with various diseases in animals and humans. The orthomyxoviruses cause diseases of the respiratory tract, most notably influenza. The related paramyxoviruses include the *respiratory syncytial virus (RSV) and the agents that cause measles, mumps, and parainfluenza.... myxovirus
(RSV) a paramyxovirus (see myxovirus) that causes infections of the nose and throat. It is a major cause of bronchiolitis and pneumonia in young children. In tissue cultures infected with the virus, cells merge together to form a conglomerate (syncytium). RSV is thought to have a role in *sudden infant death syndrome. Vulnerable children can be treated with *ribavirin, but most children just require supportive measures.... respiratory syncytial virus
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