Pergularia extensa Health Dictionary

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Pergularia Extensa: From 1 Different Sources

N. E. Br.

Synonym: P. daemia (Forsk.) Chiov.

Family: Asclepiadaceae; Periplo- caceae.

Habitat: Throughout India and hotter parts.

English: Hairknot Plant, Whitlow Plant.

Ayurvedic: Uttamaarani, Vrischikaali, Vishaanikaa. Phala- kantaka. Ajashringi is a doubtful synonym.

Siddha/Tamil: Utthaamani, Veli- paruthi.

Folk: Utaran.

Action: Plant—Uterine stimulant, tones up urinary bladder, stimulates gastric secretion, expectorant, emetic. Leaf—used for amenorrhoea, dysmenorrhoea; externally applied to carbuncles.

The plant gave betaine, a polypep- tide, hentriacontane, lupeol, alpha-and beta-amyrin, beta-sitosterol as major constituents. Seeds and stems gave car- denolides—calactin, calotropin, calo- tropagenin, uzarigenin and coroglau- cigenin.

The plant extract exhibits stimulating action on uterine and other involuntary muscles. The extracts cause rise in arterial blood pressure, increase in movement and tone of urinary bladder, and stimulation of gastric secretions. An aqueous extract of the leaves shows antibacterial activity against E. coli and Micrococcus pyogenes var. aureus.
Health Source: Indian Medicinal Plants
Author: Health Dictionary

Gymnema Sylvestre

B. Br.

Family: Asclepiadaceae.

Habitat: Central and Peninsular India.

English: Australian Cow Plant, Ipecacuanha (Indian).

Ayurvedic: Meshashringi, Meshav- ishaanikaa, Meshavalli, Chhaagal- shrngi. Ajashringi (also equated with Dolichandrone falcata and Pergularia extensa).

Unani: Gurmaar Buuti.

Siddha/Tamil: Kannu Minnayam- kodi, Passaam, Shirukurinja.

Action: Leaf—antidiabetic. Stimulates the heart and circulatory system, activates the uterus. Used in parageusia and furunculosis. Plant—diuretic, antibilious. Root— emetic, expectorant, astringent, stomachic.

Gymnemagenin, the main sapoge- nin in the leaves, yielded 3.9-4.6% of total gymnemic acids.

Gymnemic acids are antisweet principles and exhibit inhibitory effect on levels of plasma glucose.

The extract of dried leaves, given to diabetic rats at a dose of 20 mg/day per rat for 8 weeks, was found to bring about blood glucose homoeostasis by increasing serum insulin levels. Increased glycoprotein level and the resultant nephropathy, retinopathy and micro-and macro-angiopathy were also controlled.

The leaf extract (25-100 mg/kg), when orally administered to experimentally induced hyperlipidaemic rats for 2 weeks, reduced the elevated serum triglyceride and total cholesterol in a dose-dependent manner. The efficacy and antiatherosclerotic potential of the extract (100 mg/kg) were comparable to that of a lipid lowering agent, clofibrate.

In homoeopathy, a drug obtained from the leaves and roots is prescribed for both diabetes mellitus and insipidus Gymnemic acid is reported to inhibit melanin formation in vitro. It also inhibits dental plaque formation.

Dosage: Root, leaf-3-5 g powder; 50-100 ml decoction. (CCRAS.)... gymnema sylvestre

Millettia Auriculata

Baker ex Brandis.

Synonym: M. extensa Benth. ex Baker.

Family: Fabaceae.

Habitat: Sub-Himalayan tract and outer Himalaya up to 1,200 m from Kashmir to Bhutan and in Assam and Central and Southern India.

Folk: Godaar (Bihar).

Action: Root—vermifuge, pestici- dal, kills lice and ticks.

The roots, leaves and stems gave iso- flavones (including iso-auriculatin, au- ricularin) and a rotenoid, sumatrol.

Millettia racemosa Benth.

Family: Fabaceae.

Habitat: Deccan Peninsula. Folk: Godaar (Bihar).

Action: Insecticidal.

The debarked stem contains isofla- vans, isomillinol, besides behenic acid, beta-amyrin and beta-sitosterol. The isoflavans showed bactericidal and in- secticidal activity. The antibacterial activity was observed against Staphylococcus aureus and E. coli.... millettia auriculata

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