Phospholipids: From 1 Different Sources
Fats containing phosphorous, and, along with cholesterol, the primary constituents of cell membranes.
A descriptive term, rather than chemical one, for fats. Broadly, it means true fats (like triglycerides), lipoids (like phospholipids) and sterols (like cholesterol).... lipid
A sugar compound that is one constituent of some phospholipids (see LIPID) found in cells. It is found in many foods but, although sometimes classi?ed as a VITAMIN, it is not a vital part of the human diet.... inositol
A LIPID, the molecule of which contains a chemical derivative of PHOSPHORUS called phosphate. This type of lipid, which includes cephalins, lecithins and plasmalogens, is found in all tissues and organs, especially the BRAIN. Phospholipids are produced in the LIVER and and take part in many of the body’s metabolic activities (see METABOLISM).... phospholipid
Abelmoschus moschatusMalvaceaeSan: Latakasturika Hin, Guj,Ben: Mushkdana Mal: Kasthurivenda Mar: Kasthuri- bhendiTel: Kasturi bendaTam: VarttilaikasturiKan: Kasturi bende Ass: GorukhiakoraiImportance: Ambrette, also popularly known as musk or Muskmallow, is an erect annual herb which yields musk-like scented seeds and woos everybody through its sensuous musky fragrance. Every part of this medicinal plant is used in one or the other way. Seeds are effective aphrodisiac and antispasmodic, and used in tonics. They check vomiting and cure diseases due to kapha and vata and are useful in treating intestinal disorders, urinary discharge, nervous disorders, hysteria, skin diseases, snake bites, pruritus, leucoderma and general debility. Flower infusion is contraceptive. The leaves and roots are used for gonorrhoea and to treat boils and swellings.Ambrette oil of commerce is extracted from the seeds and is used in perfumery, flavouring, cosmetic and agarbathi industries. The essential oil is employed in non-alcoholic beverages, ice-creams, candies and baked foods. The aromatic concrete and absolute, extracted from seeds are used as base material for preparing high grade perfumes, scents and cosmetics. It is also known for exalting, amplifying and diffusing effects it imparts to perfumes. It blends well with rose, neroli, and sandal wood oil and aliphatic aldehydes.The flowers are in great demand for making ‘zarda’ a flavoured tobacco in India. The seeds are mixed with tea and coffee for flavour. The seed is rich in essential amino acids and is used as cattle or poultry feed. The stem bark yields a good quality fibre. Seeds are used to protect woollen garments against moth and it imparts a musky odour to sachets, hair powder, panmasala and incense. Its tender shoots are used in soups, green pods as vegetable and seed husk in flower arrangements. From perfumes to panmasalas and tonics, it is the musky musk all the way. In addition to internal consumption, its seeds are exported to Canada, France and UK because of its diversified uses (Srinivasan et al, 1997).Distribution: The musk plant is a native of India and it grows in the tropical subtropical and hilly regions of the country; particularly in the states of Maharashta, Gujarat, Madhyapresh, Tamil Nadu and Kerala. More than 50 collections of the plant are maintained by the National Bureau of Plant Genetic Resources (NBPGR), New Delhi and its regional station in Akola, Maharashtra.Botany: Abelmoschus moschatus Medicus syn. Hibiscus abelmoshus Linn. belongs to Family Malvaceae. Muskmallow is an erect annual or biennial hirsute or hispid herb of 60-180 cm height. The leaves are simple polymorphous, usually palmately 3-7 lobed; lobes narrow, acute or oblong-ovate, crenate, serrate or irregularly toothed, hairy on both surfaces. Flowers are large and bright yellow with purple centre. Fruits are fulvous, hairy and capsular. Seeds are many, subreniform, black or greyish - brown and musk scented (Husain et al, 1992).Agrotechnology: Ambrette is a hardy plant which can be grown in varied climate under tropical and subtropical conditions. It can be grown both as a rainfed crop and as an irrigated crop. It grows on well drained loamy and sandy loam soils. Loamy soils with neutral pH and plenty of organic matter are ideal for its cultivation.Musk of propagated through seeds. The optimum time of sowing is June-July with pre- monsoon showers. The land is prepared well by ploughing, harrowing and levelling. Well decomposed FYM or compost is incorporated into the soil at 10 - 15 t/ha. Ridges and furrows are formed giving a spacing of 60 - 100 cm. Seed rate is 2-3 kg/ha. Seeds are soaked in water before sowing for 24 hours. Two to three seeds are sown per hole at 60 cm spacing on one side of the ridge at a depth of 1 cm and covered with a pinch of sand or loose soil. It takes 5-7 days for proper germination. After germination, extra seedlings are thinned out leaving one healthy growing plant per hole within 20 days. Fertilisers are applied at 120:40:40 kg N, P2O5, K2O/ha generally. However, a dose 160:80:80 kg/ha is recommended for best yields of seed and oil. Phosphorus is applied fully as basal. N and K are applied in 3 equal doses at planting, 2 and 4 months after planting. Fertilizers are applied 10 cm away from the plants. For irrigated crop, field is irrigated soon after sowing. Irrigation is given twice a week during the initial period and once a week thereafter. The field is kept weed free by regular weeding during the growing period (Farooqi and Khan, 1991).Musk plants suffer from pests like spider mites, fruit bores and leaf eating caterpillars. Diseases like powdery mildew and wilt are also observed on the plant. Spider mites and powdery mildew are controlled by spraying 30g wettable sulphur in 10 litres of water. Pod borers can be controlled by spraying 20ml oxydemeton methyl in 10 litres of water.The crop starts flowering about 75 days after sowing. The flowers set into fruits in 3-4 days and the pods take nearly a month to mature. Flowering and fruit setting extends from October to April. Harvesting is arduous. Fruits have to be plucked as soon as they attain black colour; otherwise, they split and seeds scatter. Therefore, weekly collection of pods is necessary and in all 20-25 pluckings may be required as it is a 170-180 days duration crop. The fruits are further dried and threshed to separate seeds. The seed yield is 1-1.5 /haPostharvest technology:. The oil is extracted from seed by steam distillation followed by solvent extraction.The concrete of solvent extraction is further extracted with alcohol to get the absolute, that is, the alcohol soluble volatile concentrate.Properties and activity: The fatty oil of seeds contain phospholipids as 2 - cephalin, phosphatidylserine and its plasmalogen and phosphatidyl choline plasmalogen. Absolute contains farnesol and ambrettolic acid lactone. - sitosterol and its - d - glucosides are isolated from leaves. Petals contain -sitosterol, flavonoid myricetin and its glucoside. Anthocyanins like cyanidin - 3 - sambubioside and cyanidin - 3 - glucoside are present in the flowers. (Chopra and Nayar, 1980) Seeds are aphrodisiac, antispasmodic, diuretic, demulcent, antiseptic, stomachic, tonic, carminative, antihysteric, antidiarrhoeal, ophthalmic, cardiac and antivenum.... ambrette
These are organized blobs of fats, synthesized in the submucosa of the small intestine out of dietary fats, phospholipids, specialized proteins and cholesterol, carried out of the intestinal tract by the lymph, and slowly released into the bloodstream. In the capillaries, the triglycerides inside the chylomicrons, recognized by their protein markers, are absorbed into the tissues for fuel or storage, and the outside cholesterol and phospholipid transport-cover continues through the blood to be absorbed by the liver for its use. This sideways approach takes (ideally) a large part of dietary fats into the lymph back alleys, spreading their release into the bloodstream out over many hours, thereby avoiding short-term blood fat and liver fat overload. To synthesize the maximum amount of dietary fats into chylomicrons, you need well-organized emulsification and digestion of lipids by the gallbladder and pancreas.... chylomicrons
Naturally produced in the LUNGS by cells called pneumocytes, this substance is a mixture of phospholipids (see PHOSPHOLIPID) and LIPOPROTEINS. Present in ?uid lining the alveoli (see ALVEOLUS) in the lungs, their action helps maintain their patency. Premature babies may have a de?ciency of surfactant, a disorder which causes severe breathing diffculties – RESPIRATORY DISTRESS SYNDROME or hyaline membrane disease – and HYPOXIA. They will need urgent respiratory support, which includes oxygen and the administration (via an endotracheal tube) of a specially prepared surfactant such as beractant (bovine lung extract) or edfosceril palmitate.... pulmonary surfactant
Very Low Density Lipids. These are blood transport fats, consisting mainly of triglycerides (made from sugar by the liver) and loosely covered in specialized proteins and phospholipids so they don’t dissolve in the blood and the target tissues can recognize them. Chronic elevation occurs when the tissues cannot absorb them or the liver is overwhelmed by carbohydrates...such as in alcoholism, some hepatitis, and diabetes.... vldl
A general term for fats and oils. Lipids include triglycerides (simple fats), phospholipids (important constituents of cell membranes and nerve tissue), and sterols, such as cholesterol.... lipids
Gaertn.
Synonym: Phyllanthus emblica Linn.
Family: Euphorbiaceae.
Habitat: Native to tropical Southeast Asia; distributed throughout India; also planted in public parks.
English: Emblic, Indian gooseberry.
Ayurvedic: Aaamalaki, Aaamalaka, Dhaatri, Kaayasthaa, Amoghaa, Amritaphala, Amla, Aaamalaa, Dhaatriphala, Vayasyaa, Vrshya, Shiva, Hattha.
Unani: Aamalaa, Amlaj.
Siddha/Tamil: Nellikkaai, Nelli.
Action: Fruit—antianaemic, anabolic, antiemetic, bechic, astringent, antihaemorrhagic, antidiarrhoeal, diuretic, antidiabetic, carminative, antioxidant. Used in jaundice, dyspepsia, bacillary dysentery, eye trouble and as a gastrointestinal tonic. Juice with turmeric powder and honey is prescribed in diabetes insipidus. Seed—antibilious, antiasthmatic. Used in bronchitis. Bark—astringent. Leaf—juice is given in vomiting.
A decoction of powdered pericarp is prescribed for paptic ulcer.
Key application: As an antacid. (Indian Herbal Pharmacopoeia.).The fruit is an important source of vitamin C, minerals and amino acids. The edible fruit tissue contains protein concentration threefold and vitamin C (ascorbic acid) concentration 160-fold than those of apple. The fruit also contains considerably higher concentration of most minerals and amino acids than apple.The fruit gave cytokinine-like substances identified as zeatin, zeatin ribo- side and zeatin nucleotide; suspension culture gave phyllembin. Phyllem- bin exhibits CNS depressant and spasmolytic activity, potentiates action of adrenaline and hypnotic action of Nembutal.The leaves contain gallic acid (10.8 mg/g dry basis), besides ascorbic and music acid. The methanol extract of the leaves is found to be effective in rat paw inflammation.The bark contains tannin identified as mixed type of proanthocyanidin.The fruit contains superoxide dis- mutase 482.14 units/g fresh weight and exhibits antisenescent (anti-aging) activity. Fruit, juice, its sediment and residue are antioxidant due to gallic acid. EtOH (50%) extract—antiviral.Aqueous extract of the fruit increases cardiac glycogen level and decreases serum GOT, GPT and LDH in rats having induced myocardial necrosis.Preliminary evidence suggests that the fruit and its juice may lower serum cholesterol, LDL, triglycerides and phospholipids without affecting HDL levels and may have positive effect on atherosclerosis. (Eur J clin Nutr, 42, 1988, 939-944; PhytotherRes, 14, 2000, 592-595.)An aqueous extract of the fruit has been reported to provide protection against radiation-induced chromosomal damage in both pre-and postirradiation treatment. The fruit is reported to enhance natural killer cell activity and antibody dependent cellular cytotoxicity in mice bearing Dalton's lymphoma ascites tumour. The extract of the fruit and ascorbic acid prevented hepatotoxic and nephrotoxic effects induced by lead and aluminium. The toxicity could be counteracted to a great extent by the fruit extract than by an amount of ascorbic acid alone equivalent to that contained in fruits. (The fruit can be used as a dietary supplement to counteract prolonged exposure to metals in population in industrial areas.)The fruits are reported to activate trypsin (proteolytic enzyme) activity.The fruits can be used as coagulant in the treatment of water and can purify low turbidity water.The fruits can be consumed safely all round the year.
Dosage: Fresh fruit—10-20 g; pulp juice—5-10 ml. (API Vol. I.)... emblica officinalis
n. one of a group of *phospholipids that are constituents of cell membranes and are particularly abundant in the brain.... cephalin
n. a basic compound important in the synthesis of phosphatidylcholine (lecithin) and other *phospholipids and of *acetylcholine. It is also involved in the transport of fat in the body. Choline is sometimes classed as a vitamin but, although it is essential for life, it can be synthesized in the body.... choline
an inherited (autosomal *recessive) disorder of lipid metabolism due to a defect in the enzyme sphingomyelinase and resulting in accumulation of sphingomyelin (a sphingolipid) and other phospholipids in the bone marrow, brain, liver, and spleen. Patients present with neurological problems, learning disabilities, and enlargement of the liver and spleen at a young age. There are four known types of the disease. [A. Niemann (1880–1921), German paediatrician; L. Pick (1868–1944), German pathologist]... niemann–pick disease
n. one of a group of enzymes capable of catalysing the hydrolysis of phosphoric acid esters. An example is glucose-6-phosphatase, which catalyses the hydrolysis of glucose-6-phosphate to glucose and phosphate. Phosphatases are important in the absorption and metabolism of carbohydrates, nucleotides, and phospholipids and are essential in the calcification of bone. Acid phosphatase is present in kidney, semen, serum, and the prostate gland. Alkaline phosphatase occurs in teeth, developing bone, plasma, kidney, and intestine.... phosphatase
Pongamia pinnataPapilionaceaeSan: Karanj;Hin: Karanja, Dittouri;Ben: Dehar karanja;Mal: Ungu, Pongu; Guj, Mar, Pun: Karanj;Kan: Hongae;Tel: Kangu;Tam: Puggam; Ass: Karchaw; Ori: KoranjoImportance: Indian beech, Pongam oil tree or Hongay oil tree is a handsome flowering tree with drooping branches, having shining green leaves laden with lilac or pinkish white flowers. The whole plant and the seed oil are used in ayurvedic formulations as effective remedy for all skin diseases like scabies, eczema, leprosy and ulcers. The roots are good for cleaning teeth, strengthening gums and in gonorrhoea and scrofulous enlargement. The bark is useful in haemorhoids, beriberi, ophthalmopathy and vaginopathy. Leaves are good for flatulence, dyspepsia, diarrhoea, leprosy, gonorrhoea, cough, rheumatalgia, piles and oedema. Flowers are given in diabetes. Fruits overcomes urinary disease and piles. The seeds are used in inflammations, otalgia, lumbago, pectoral diseases, chronic fevers, hydrocele, haemorrhoids and anaemia. The seed oil is recommended for ophthalmia, haemorrhoids, herpes and lumbagoThe seed oil is also valued for its industrial uses. The seed cake is suggested as a cheap cattle feed. The plant enters into the composition of ayurvedic preparations like nagaradi tailam, varanadi kasayam, varanadi ghrtam and karanjadi churna.It is a host plant for the lac insect. It is grown as a shade tree. The wood is moderately hard and used as fuel and also for making agricultural implements and cart- wheels.Distribution: The plant is distributed throughout India from the central or eastern Himalaya to Kanyakumari, especially along the banks of streams and rivers or beach forests and is often grown as an avenue tree. It is distributed in Sri Lanka, Burma, Malaya, Australia and Polynesia.Botany: Pongamia pinnata (Linn.) Pierre syn. P. glabra Vent., Derris indica (Lam.) Bennet, Cystisus pinnatus Lam. comes under family Papilionaceae. P. pinnata is a moderate sized, semi -evergreen tree growing upto 18m or more high, with a short bole, spreading crown and greyish green or brown bark. Leaves imparipinnate, alternate, leaflets 5-7, ovate and opposite. Flowers lilac or pinkish white and fragrant in axillary recemes. Calyx cup-shaped, shortly 4-5 toothed, corolla papilionaceous. Stamens 10 and monadelphous, ovary subsessile, 2-ovuled with incurved, glabrous style ending in a capitate stigma. Pod compressed, woody, indehiscent, yellowish grey when ripe varying in size and shape, elliptic to obliquely oblong, 4.0-7.5cm long and 1.7-3.2cm broad with a short curved beak. Seeds usually 1, elliptic or reniform, wrinkled with reddish brown, leathery testa.Agrotechnology: The plant comes up well in tropical areas with warm humid climate and well distributed rainfall. Though it grows in almost all types of soils, silty soils on river banks are most ideal. It is tolerant to drought and salinity. The tree is used for afforestation, especially in watersheds in the drier parts of the country. It is propagated by seeds and vegetatively by rootsuckers. Seed setting is usually in November. Seeds are soaked in water for few hours before sowing. Raised seed beds of convenient size are prepared, well rotten cattle manure is applied at 1kg/m2 and seeds are uniformly broadcasted. The seeds are covered with a thin layer of sand and irrigated. One month old seedlings can be transplanted into polybags, which after one month can be planted in the field. Pits of size 50cm cube are dug at a spacing of 4-5m, filled with top soil and manure and planted. Organic manure are applied annually. Regular weeding and irrigation are required for initial establishment. The trees flower and set fruits in 5 years. The harvest season extends from November- June. Pods are collected and seeds are removed by hand. Seed, leaves, bark and root are used for medicinal purposes. Bark can be collected after 10 years. No serious pests and diseases are reported in this crop.Properties and activity: The plant is rich in flavonoids and related compounds. Seeds and seed oil, flowers and stem bark yield karanjin, pongapin, pongaglabrone, kanugin, desmethoxykanugin and pinnatin. Seed and its oil also contain kanjone, isolonchocarpin, karanjachromene, isopongachromene, glabrin, glabrachalcone, glabrachromene, isopongaflavone, pongol, 2’- methoxy-furano 2”,3”:7,8 -flavone and phospholipids. Stem-bark gives pongachromene, pongaflavone, tetra-O-methylfisetin, glabra I and II, lanceolatin B, gamatin, 5-methoxy- furano 2”,3”:7,8 -flavone, 5-methoxy-3’,4’-methelenedioxyfurano 2”,3”:7,8 -flavone and - sitosterol. Heartwood yields chromenochalcones and flavones. Flowers are reported to contain kanjone, gamatin, glabra saponin, kaempferol, -sitosterol, quercetin glycocides, pongaglabol, isopongaglabol, 6-methoxy isopongaglabol, lanceolatin B, 5-methoxy-3’,4’- methelenedioxyfurano 8,7:4”,5” -flavone, fisetin tetramethyl ether, isolonchocarpin, ovalichromene B, pongamol, ovalitenon, two triterpenes- cycloart-23-ene,3 ,25 diol and friedelin and a dipeptide aurantinamide acetate.Roots and leaves give kanugin, desmethoxykanugin and pinnatin. Roots also yield a flavonol methyl ether-tetra-O-methyl fisetin. The leaves contain triterpenoids, glabrachromenes I and II, 3’-methoxypongapin and 4’-methoxyfurano 2”,3”:7,8 -flavone also. The gum reported to yield polysaccharides (Thakur et al, 1989; Husain et al, 1992).Seeds, seed oil and leaves are carminative, antiseptic, anthelmintic and antirheumatic. Leaves are digestive, laxative, antidiarrhoeal, bechic, antigonorrheic and antileprotic. Seeds are haematinic, bitter and acrid. Seed oil is styptic and depurative. Karanjin is the principle responsible for the curative properties of the oil. Bark is sweet, anthelmintic and elexteric.... indian beech
Nutrients that provide the body with its most concentrated form of energy. Fats, which are also called lipids, are compounds containing chains of carbon and hydrogen with very little oxygen. Chemically, fats consist mostly of fatty acids combined with glycerol. They are divided into 2 main groups, saturated and unsaturated, depending on the proportion of hydrogen atoms. If the fatty acids contain the maximum possible quantity of hydrogen, the fats are saturated. If some sites on the carbon chain are unoccupied by hydrogen, they are unsaturated; when many sites are vacant, they are polyunsaturated. Monounsaturated fats are unsaturated fats with only one site that could take an extra hydrogen. Animal fats, such as those in meat and dairy products, are largely saturated, whereas vegetable fats tend to be unsaturated.
Fats are usually solid at room temperature; oils are liquid. The amount and types of fat in the diet have important implications for health. A diet containing a large amount of fat, particularly saturated fat, is linked to an increased risk of atherosclerosis and subsequent heart disease and stroke.
Some dietary fats, mainly triglycerides (combinations of glycerol and 3 fatty acids), are sources of the fat-soluble vitamins A, D, E, and K and of essential fatty acids. Triglycerides are the main form of fat stored in the body. These stores act as an energy reserve and also provide insulation and a protective layer for delicate organs. Phospholipids are structural fats found in cell membranes. Sterols, such as cholesterol, are found in animal and plant tissues; they have a variety of functions, often being converted into hormones or vitamins.
Dietary fats are first emulsified by bile salts before being broken down by lipase, a pancreatic enzyme. They are absorbed via the lymphatic system before entering the bloodstream.Lipids are carried in the blood bound to protein; in this state they are known as lipoproteins. There are 4 classes of lipoprotein: very low-density lipoproteins (VLDLs), low-density lipoproteins (LDLs), high-density lipoproteins (HDLs), and chylomicrons. LDLs and VLDLs contain large amounts of cholesterol, which they carry through the bloodstream and deposit in tissues. HDLs pick up cholesterol and carry it back to the liver for processing and excretion. High levels of LDLs are associated with atherosclerosis, whereas HDLs have a protective effect. (See also nutrition.)... fats and oils
the process whereby platelets adhere to collagen released from endothelial cells in damaged blood vessels and aggregate to form a plug. An important metabolic pathway in platelets converts membrane phospholipids to *thromboxane A2 (TXA2), which can activate platelets. ADP, released from platelet granules, and *thrombin are other activators. The adhesive and aggregation reactions of platelets are mediated through surface membrane glycoproteins (Glp), Glp Ib and Glp IIb/IIIa. Aspirin acts as an *antiplatelet drug by irreversibly inhibiting one of the enzymes of this pathway, cyclo-oxygenase. Clopidrogel inhibits the ADP receptor on platelet membranes, and *abciximab blocks platelet aggregation by inhibiting Glp IIb/IIIa (see illustration overleaf).... platelet activation
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