Phototoxicity Health Dictionary

Phototoxicity: From 1 Different Sources


n. damage caused by prolonged exposure to light; for example, retinal phototoxicity is damage to the retina of the eye as a result of prolonged exposure to light.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Ruta Graveolens

Linn.

Family: Rutaceae.

Habitat: Native to Mediterranean region; cultivated all over India.

English: Garden Rue.

Unani: Sudaab, Suddaab.

Siddha/Tamil: Aruvada.

Action: Herb—stimulating, antispasmodic, stomachic; irritant, abortifacient. Used as an emme- nagogue, in hysterical conditions, cough and croupy affections, colic and flatulence. Leaf—used in atonic amenorrhoea, menorrhoea and colic. Externally, used for sciatica, headache, muscular chest pain, bronchitis and arthritic conditions. (Fresh juice of leaves, internally, can lead to painful irritations of the stomach and intestines). Oil— antispasmodic, antiepileptic, em- menagogue, rubefacient. (Toxic in large doses.)

Ruta graveolens has been included among unapproved herbs by German Commission E.

The herb contains a volatile oil, with 2-undecanone (30.73) 2-nona- none (18.06), 2-nonyl acetate (11.03), psoralen (1.28) and bergapten and xan- thotoxin (7.24%); rutin (about 2%). The flavonoids include quercetin; cou- marins include bergapten, daphnore- tin, isoimperatorin, naphthoherniarin, psoralen, pangelin, rutamarin, rutarin, scopoletin and umbelliferone. Tissue culture of the plant gave furacridone alkaloids. Tissue culture of the root gave gravacridondiol and its glucoside.

The spasmolytic activity of the herb is attributed to the presence of bergapten, xanthotoxin and the essential oil. Anti-inflammatory and antitumour activity is due to rutin. The furo- coumarins are responsible for the herb's phototoxicity.

The herb is hepatotoxic, and is con- traindicated in kidney diseases and bleeding disorders. (Sharon M. Herr.) Maximum safe level is 0.001% for Rue and 0.0002% for the oil. (Natural Medicines Comprehensive Database, 2007.)... ruta graveolens

Deertongue

Carphephorus odoratissimus

FAMILY: Asteraceae (Compositae)

SYNONYMS: Trilisa odoratissima, Liatris odoratissima, Frasera speciosa, hound’s tongue, deer’s tongue, Carolina vanilla, vanilla leaf, wild vanilla, vanilla trilisa, whart’s tongue, liatrix (oleoresin or absolute).

GENERAL DESCRIPTION: A herbaceous perennial plant distinguished by a naked receptacle and feathery pappus, with large, fleshy, dark green leaves, clasped at the base. When fresh, the leaves have little odour but when dried they acquire a vanilla-like odour, largely due to the coumarin that can be seen in crystals on the upper sides of the leaves.

DISTRIBUTION: Native to eastern USA; gathered on the savannah land between North Carolina and Florida.

OTHER SPECIES: There are several species of deertongue native to America, for example blazing star or prairie pine (Liatris squarrosa), and gayfeather (L. spicata). Not to be confused with the common vanilla (Vanilla planifolia) or with the European hound’s tongue (Cynoglossum officinale), all of which have been used in herbal medicine.

HERBAL/FOLK TRADITION: The roots have been used for their diuretic effects, and applied locally for sore throats and gonorrhoea. It has also been used as a tonic in treating malaria. In folklore the plant is associated with contraception and sterility in women.

ACTIONS: Antiseptic, demulcent, diaphoretic, diuretic, febrifuge, stimulant, tonic.

EXTRACTION: Oleoresin by solvent extraction from the dried leaves.

CHARACTERISTICS: A dark green, heavy, viscous liquid with a rich, herbaceous, new-mown hay scent. It blends well with oakmoss, labdanum, lavandin, frankincense, clove, patchouli and oriental-type fragrances.

PRINCIPAL CONSTITUENTS: Mainly coumarin (1.6 per cent), with dihydrotoumarin and terpenes, aldehydes and ketones.

SAFETY DATA: ‘Coumarin has toxic properties including liver injury and haemorrhages.’. (There is also the possibility of dermal irritation and phototoxicity due to the lactones present.)

AROMATHERAPY/HOME: USE None.

OTHER USES: The oleoresin is used as a fixative and fragrance component in soaps, detergents and perfumery work. Used for flavouring tobacco and; also employed for the isolation of coumarin.... deertongue

Verbena, Lemon

Aloysia triphylla

FAMILY: Verbenaceae

SYNONYMS: A. citriodora, Verbena triphylla, Lippia citriodora, L. triphylla, verbena, herb Louisa.

GENERAL DESCRIPTION: A handsome deciduous perennial shrub up to 5 metres high with a woody stem, very fragrant, delicate, pale green, lanceolate leaves arranged in threes, and small, pale purple flowers. Often grown as an ornamental bush in gardens.

DISTRIBUTION: Native of Chile and Argentina; cultivated (and found semi-wild) in the Mediterranean region – France, Tunisia, Algeria – as well as Kenya and China. The oil is mainly produced in southern France and North Africa.

OTHER SPECIES: Botanically related to the oregano family – see Botanical Classification section. Not to be mistaken for the so-called ‘Spanish verbena’ or ‘verbena’ oil (Spanish) (Thymus hiamalis), nor confused with the herb ‘vervain’ (Verbena officinalis). This is further confused since the French name for verbena is verveine (Verveine citronelle, Verveine odorante).

HERBAL/FOLK TRADITION: ‘The uses of lemon verbena are similar to those of mint, orange flowers and melissa.’. It is indicated especially in nervous conditions which manifest as digestive complaints. The dried leaves are still used as a popular household tea especially on the Continent, both as a refreshing, uplifting ‘pick-me-up’ and to help restore the liver after a hang-over.

ACTIONS: Antiseptic, antispasmodic, carminative, detoxifying, digestive, febrifuge, hepatobiliary stimulant, sedative (nervous), stomachic.

EXTRACTION: Essential oil by steam distillation from the freshly harvested herb.

CHARACTERISTICS: A pale olive or yellow mobile liquid with a sweet, fresh, lemony, fruity-floral fragrance. It blends well with neroli, palmarosa, olibanum, Tolu balsam, elemi, lemon and other citrus oils.

PRINCIPAL CONSTITUENTS: Citral (30–35 per cent), nerol and geraniol, among others.

SAFETY DATA: Possible sensitization; phototoxicity due to high citral levels. Other safety data is unavailable at present – however, true verbena oil is virtually non-existent. Most so-called ‘verbena oil’ is either from the Spanish verbena (an inferior oil), or a mix of lemongrass, lemon, citronella, etc.

AROMATHERAPY/HOME: USE

Digestive system: Cramps, indigestion, liver congestion.

Nervous system: Anxiety, insomnia, nervous tension and stress-related conditions.

OTHER USES: Used in perfumery and citrus colognes – ‘eau de verveine’ is still popular in France, Europe and America.... verbena, lemon




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