Piles Health Dictionary

Piles: From 3 Different Sources


A common name for haemorrhoids.
Health Source: BMA Medical Dictionary
Author: The British Medical Association

Haemorrhoids

Haemorrhoids, or piles, are varicose (swollen) veins in the lining of the ANUS. They are very common, affecting nearly half of the UK population at some time in their lives, with men having them more often and for a longer time.

Varieties Haemorrhoids are classi?ed into ?rst-, second- and third-degree, depending on how far they prolapse through the anal canal. First-degree ones do not protrude; second-degree piles protrude during defaecation; third-degree ones are trapped outside the anal margin, although they can be pushed back. Most haemorrhoids can be described as internal, since they are covered with glandular mucosa, but some large, long-term ones develop a covering of skin. Piles are usually found at the three, seven and eleven o’clock sites when viewed with the patient on his or her back.

Causes The veins in the anus tend to become distended because they have no valves; because they form the lowest part of the PORTAL SYSTEM and are apt to become over?lled when there is the least interference with the circulation through the portal vein; and partly because the muscular arrangements for keeping the rectum closed interfere with the circulation through the haemorrhoidal veins. An absence of ?bre from western diets is probably the most important cause. The result is that people often strain to defaecate hard stools, thus raising intra-abdominal pressure which slows the rate of venous return and engorges the network of veins in the anal mucosa. Pregnancy is an important contributory factor in women developing haemorrhoids. In some people, haemorrhoids are a symptom of disease higher up in the portal system, causing interference with the circulation. They are common in heart disease, liver complaints such as cirrhosis or congestion, and any disease affecting the bowels.

Symptoms Piles cause itching, pain and often bleeding, which may occur whenever the patient defaecates or only sometimes. The piles may prolapse permanently or intermittently. The patient may complain of aching discomfort which, with the pain, may be worsened.

Treatment Prevention is important; a high-?bre diet will help in this, and is also necessary after piles have developed. Patients should not spend a long time straining on the lavatory. Itching can be lessened if the PERINEUM is properly washed, dried and powdered. Prolapsed piles can be replaced with the ?nger. Local anaesthetic and steroid ointments can help to relieve symptoms when they are relatively mild, but do not remedy the underlying disorder. If conservative measures fail, then surgery may be required. Piles may be injected, stretched or excised according to the patient’s particular circumstances.

Where haemorrhoids are secondary to another disorder, such as cancer of the rectum or colon, the underlying condition must be treated – hence the importance of medical advice if piles persist.... haemorrhoids

Ficus

Ficus spp.

Moraceae

The genus Ficus constitutes an important group of trees with immense medicinal value. It is a sacred tree of Hindus and Buddhists. Among the varied number of species, the most important ones are the four trees that constitute the group “Nalpamaram”, namely, F. racemosa, F. microcarpa, F. benghalensis and F. religiosa (Athi, Ithi, Peral and Arayal respectively).

1. Ficus racemosa Linn. syn. F. glomerata Roxb.

Eng: Cluster fig, Country fig

San: Udumbarah, Sadaphalah

Hin: Gular, Umar

Ben: Jagya dumur

Mal, Tam,

Kan: Athi

Tel: Udambaramu, Paidi

Gular fig, Cluster fig or Country fig, which is considered sacred, has golden coloured exudate and black bark. It is distributed all over India. Its roots are useful in treating dysentery. The bark is useful as a wash for wounds, highly efficacious in threatened abortions and recommended in uropathy. Powdered leaves mixed with honey are given in vitiated condition of pitta. A decoction of the leaves is a good wash for wounds and ulcers. Tender fruits (figs) are used in vitiated conditions of pitta, diarrhoea, dyspepsia and haemorrhages. The latex is administered in haemorrhoids and diarrhoea (Warrier et al, 1995). The ripe fruits are sweet, cooling and are used in haemoptysis, thirst and vomiting (Nadkarni, 1954; Aiyer et al, 1957; Moos, 1976). Nalpamaradi coconut oil, Candanasava, Valiya Arimedastaila, Dinesavalyadi Kuzhambu, Abhrabhasma, Valiya candanaditaila, etc. are some important preparations using the drug (Sivarajan et al, 1994).

It is a moderate to large-sized spreading laticiferous, deciduous tree without many prominent aerial roots. Leaves are dark green and ovate or elliptic. Fruit receptacles are 2-5cm in diameter, sub- globose or pyriform arranged in large clusters on short leafless branches arising from main trunk or large branches. Figs are smooth or rarely covered with minute soft hairs. When ripe, they are orange, dull reddish or dark crimson. They have a pleasant smell resembling that of cedar apples. The bark is rusty brown with a fairly smooth and soft surface, the thickness varying from 0.5-2cm according to the age of the trunk or bark. Surface is with minute separating flakes of white tissue. Texture is homogeneously leathery (Warrier et al, 1995).

Stem-bark gives gluanol acetate, -sitosterol, leucocyanidin-3-O- -D-glucopyrancoside, leucopelargonidin-3-O- -D-glucopyranoside, leucopelargonidin -3-O- -L-rhamnopyranoside, lupeol, ceryl behenate, lupeol acetate and -amyrin acetate. Stem- bark is hypoglycaemic and anti-protozoal. Gall is CVS active. Bark is tonic and used in rinder pest diseases of cattle. Root is antidysenteric and antidiabetic. Leaf is antibilious. Latex is antidiarrhoeal and used in piles. Bark and syconium is astringent and used in menorrhagia (Husain et al, 1992).

2. Ficus microcarpa Linn. f. syn. F. retusa auct. Non. Linn.

San: Plaksah; Hin,

Ben: Kamarup;

Mal: Ithi, Ithiyal;

Tam: Kallicci, Icci;

Kan: Itti;

Tel: Plaksa

Plaksah is the Ficus species with few branches and many adventitious roots growing downward. It is widely distributed throughout India and in Sri Lanka, S. China, Ryuku Isles and Britain. Plakasah is one of the five ingredients of the group panchvalkala i.e, five barks, the decoction of which is extensively used to clear ulcers and a douche in leucorrhoea in children. This decoction is administered externally and internally with satisfactory results. Plaksah is acclaimed as cooling, astringent, and curative of raktapitta doshas, ulcers, skin diseases, burning sensation, inflammation and oedema. It is found to have good healing property and is used in preparation of oils and ointments for external application in the treatment of ulcers (Aiyer and Kolammal, 1957). The stem-bark is used to prepare Usirasava, Gandhataila, Nalpamaradi taila, Valiya marmagulika, etc. (Sivarajan et al, 1994). The bark and leaves are used in wounds, ulcers, bruises, flatulent colic, hepatopathy, diarrhoea, dysentery, diabetes, hyperdipsia, burning sensation, haemaorrhages, erysipelas, dropsy, ulcerative stomatitis, haemoptysis, psychopathy, leucorrhoea and coporrhagia (Warrier et al,1995) F. microcarpa is a large glabrous evergreen tree with few aerial roots. Leaves are short- petioled, 5-10cm long, 2-6cm wide and apex shortly and bluntly apiculate or slightly emarginate. Main lateral nerves are not very prominent and stipules are lanceolate. Fruit receptacles are sessile and globose occurring in axillary pairs. It is yellowish when ripe without any characteristic smell. Bark is dark grey or brown with a smooth surface except for the lenticels. Outer bark is corky and crustaceous thin and firmly adherent to inner tissue. Inner bark is light and flesh coloured with firbrous texture (Warrier et al, 1995). It is also equated with many other species of the genus. viz. F. Singh and Chunekar, 1972; Kapoor and Mitra, 1979; Sharma, 1983).

The bark contains tannin, wax and saponin. Bark is antibilious. Powdered leaves and bark is found very good in rheumatic headache. The bark and leaves are astringent, refrigerant, acrid and stomachic.

3. Ficus benghalensis Linn.

Eng: Banyan tree; San: Nyagrodhah, Vatah;

Hin: Bat, Bargad;

Ben: Bar, Bot; Mar: Vada; Mal: Peral, Vatavriksham;

Tam: Alamaram, Peral;

Kan: Ala;

Tel: Peddamarri;

Guj: Vad

Banyan tree is a laticiferous tree with reddish fruits, which is wound round by aerial adventitious roots that look like many legs. It is found in the Sub-Himalayan tract and Peninsular India. It is also grawn throughout India. It is widely used in treatment of skin diseases with pitta and rakta predominance. Stem-bark, root -bark, aerial roots, leaves, vegetative buds and milky exudate are used in medicine. It improves complexion, cures erysepelas, burning sensation and vaginal disorders, while an infusion of the bark cures dysentery, diarrhoea, leucorrhoea, menorrhagia, nervous disorders and reduces blood sugar in diabetes. A decoction of the vegetative buds in milk is beneficial in haemorrhages. A paste of the leaves is applied externally to abcesses and wounds to promote suppuration, while that of young aerial roots cure pimples. Young twigs when used as a tooth brush strengthen gum and teeth (Nadkarni, 1954; Aiyer and Kolammal, 1957; Mooss,1976). The drug forms an important constituent of formulations like Nalpamaradi Coconut oil, Saribadyasava, Kumkumadi taila, Khadi ra gulika, Valiyacandanadi taila, Candanasava, etc. (Sivarajan et al, 1994). The aerial roots are useful in obstinate vomiting and leucorrhoea and are used in osteomalacia of the limbs. The buds are useful in diarrhoea and dysentery. The latex is useful in neuralgia, rheumatism, lumbago, bruises, nasitis, ulorrhagia, ulitis, odontopathy, haemorrhoids, gonorrhoea, inflammations, cracks of the sole and skin diseases (Warrier et al, 1995).

It is a very large tree up to 30m in height with widely spreading branches bearing many aerial roots functioning as prop roots. Bark is greenish white. Leaves are simple, alternate, arranged often in clusters at the ends of branches. They are stipulate, 10-20cm long and 5-12.5cm broad, broadly elliptic to ovate, entire, coriaceous, strongly 3-7 ribbed from the base. The fruit receptacles are axillary, sessile, seen in pairs globose, brick red when ripe and enclosing male, female and gall flowers. Fruits are small, crustaceous, achenes, enclosed in the common fleshy receptacles. The young bark is somewhat smooth with longitudinal and transverse row of lenticels. In older bark, the lenticels are numerous and closely spaced; outer bark easily flakes off. The fresh cut surface is pink or flesh coloured and exudes plenty of latex. The inner most part of the bark adjoining the wood is nearly white and fibrous (Warrier et al, 1995).

The bark yields flavanoid compounds A, B and C; A and C are identified as different forms of a leucoanthocyanidin and compound B a leucoanthocyanin. All the 3 were effective as hypoglycaemic agents. Leaves give friedelin, -sitosterol, flavonoids- quercetin-3-galactoside and rutin. Heart wood give tiglic acid ester of taraxasterol. Bark is hypoglycemic, tonic, astringent, antidiarrhoeal and antidiabetic. Latex is antirheumatic. Seed is tonic. Leaf is diaphoretic. Root fibre is antigonorrhoeic. Aerial root is used in debility and anaemic dysentery (Husain et al, 1992).

.4. Ficus religiosa Linn.

Eng:Peepal tree, Sacred fig; San:Pippalah, Asvatthah; Hin:Pippal, Pipli, Pipar; Mal:Arayal

Ben: Asvatha;

Tam: Arasu, Asvattam;

Kan: Aswatha;

Tel: Ravi; Mar: Ashvata, Pimpala

Peepal tree or Sacred fig is a large deciduous tree with few or no aerial roots. It is common throughout India, often planted in the vicinity of the temples. An aqueous extract of the bark has an antibacterial activity against Staphylococcus aureus and Escherichia coli. It is used in the treatment of gonorrhoea, diarrhoea, dysentery, haemorrhoids and gastrohelcosis. A paste of the powdered bark is a good absorbent for inflammatory swellings. It is also good for burns. Leaves and tender shoots have purgative properties and are also recommended for wounds and skin diseases. Fruits are laxative and digestive. The dried fruit pulverized and taken in water cures asthma. Seeds are refrigerant and laxative. The latex is good for neuralgia, inflammations and haemorrhages (Warrier et al, 1995). Decoction of the bark if taken in honey subdues vatarakta (Nadkarni, 1954; Aiyer and Kolammal, 1957; Mooss, 1976; Kurup et al, 1979). The important preparations using the drug are Nalpamaradi taila, Saribadyasava, Candanasava, Karnasulantaka, Valiyamarma gulika etc (Sivarajan et al, 1994). branches bearing long petioled, ovate, cordate shiny leaves. Leaves are bright green, the apex produced into a linear-lanceolate tail about half as long as the main portion of the blade. The receptacles occurring in pairs and are axillary, depressed globose, smooth and purplish when ripe. The bark is grey or ash coloured with thin or membranous flakes and is often covered with crustose lichen patches. The outer bark is not of uniform thickness, the middle bark in sections appear as brownish or light reddish brown. The inner part consists of layers of light yellowish or orange brown granular tissue (Warrier et al, 1995).

Bark gives -sitosterol and its glucoside. Bark is hypoglycaemic. Stem bark is antiprotozoal, anthelmintic and antiviral. Bark is astringent, antigonorrheic, febrifuge, aphrodisiac and antidysenteric. Syconium, leaf and young shoot is purgative (Husain et al, 1992).

Agrotechnology: Ficus species can be cultivated in rocky areas, unused lands, or other wastelands of the farmyard. The plant is vegetatively propagated by stem cuttings. A few species are also seed propagated. Stem cuttings of pencil thickness taken from the branches are to be kept for rooting. Rooted cuttings are to be transplanted to prepared pits. No regular manuring is required. Irrigation is not a must as a plant is hardy. The plant is not attacked by any serious pests or diseases. Bark can be collected after 15 years. Ficus species generally has an economic life span of more than hundred years. Hence bark can be regularly collected from the tree. Root, bark, leaves, fruits and latex form the economic parts (Prasad et al,1995).... ficus

Eclipta

Eclipta prostrata

Asteraceae

San: Bhrngarajah, Tekarajah;

Hin: Bhamgra, Mocakand, Babri;

Ben: Kesutthe, Kesraj;

Mal: Kannunni, Kayyonni, Kayyunnni;

Tam: Kayyantakara, Kaikeri;

Kan: Kadiggagaraga;

Tel: Guntagalijeran; Arab: Kadim-el-bint

Importance: Eclipta is one of the ten auspicious herbs that constitute the group dasapuspam which is considered to destroy the causative factors of all unhealthy and unpleasant features and bestow good health and prosperity. The members of this group cure wounds and ulcers as well as fever caused by the derangement of the tridosas - vata, pitta and kapha. It is used in hepatitis, spleen enlargements, chronic skin diseases, tetanus and elephantiasis. The leaf promotes hair growth and use as an antidote in scorpion sting. The root is used as an emetic, in scalding of urine, conjuctivitis and as an antiseptic to ulcers and wound in cattle. It is used to prevent abortion and miscarriage and also in cases of uterine pains after the delivery. The juice of the plant with honey is given to infants for expulsion of worms. For the relief in piles, fumigation with Eclipta is considered beneficial. A decoction of the leaves is used in uterine haemorrhage. The paste prepared by mincing fresh plants has got an antiinflammatory effect and may be applied on insect bites, stings, swellings and other skin diseases. In Ayurveda, it is mainly used in hair oil, while in Unani system, the juice is used in “Hab Miskeen Nawaz” along with aconite, triphala, Croton tiglium, Piper nigium, Piper longum, Zingiber officinale and minerals like mercury, sulphur, arsenic, borax, etc. for various types of pains in the body. It is also a constituent of “Roghan Amla Khas” for applying on the hair and of “Majun Murrawah-ul-arwah”.

Distribution: This plant is widely distributed in the warm humid tropics with plenty of rainfall. It grows commonly in moist places as a weed all over plains of India.

Botany: Eclipta prostrata (Linn) Linn. syn. E. alba Hassk. is an annual, erect or postrate herb, often rooting at nodes. Leaves are sessile, 2.5-7.5cm long with white appressed hairs. Floral heads are 6-8 mm in diameter, solitary and white. Fruit is an achene, compressed and narrowly winged. Sometimes, Wedelia calendulacea, which resembles Eclipta prostrata is used for the same purpose.

Properties and activity: The leaves contain stigmasterol, -terthienylmethanol, wedelolactone, dismethylwedelolactone and dismethylwedelolactone-7-glucoside. The roots give hentriacontanol and heptacosanol. The roots contain polyacetylene substituted thiophenes. The aerial part is reported to contain a phytosterol, -amyrin in the n-hexane extract and luteolin-7-glucoside, -glucoside of phytosterol, a glucoside of a triterpenic acid and wedelolactone in polar solvent extract. The polypeptides isolated from the plant yield cystine, glutamic acid, phenyl alanine, tyrosine and methionine on hydrolysis. Nicotine and nicotinic acid are reported to occur in this plant.

The plant is anticatarrhal, febrifuge, antidontalgic, absorbent, antihepatic, CVS active, nematicidal, ovicidal and spasmolytic in activity. The alcoholic extract of entire plant has been reported to have antiviral activity against Ranikhet disease virus. Aqueous extract of the plant showed subjective improvement of vision in the case of refractive errors. The herbal drug Trefoli, containing extracts of the plant in combination with others, when administered to the patients of viral hepatitis, produced excellent results.... eclipta

Nagadanti

Baliospermum montanum

Euphorbiaceae

San: Danti;

Hin: Danti;

Mal: Danti, Nagadanti;

Tam: Nakatanti;

Tel: Nelajidi

Importance: Danti or Nagadanti is a stout undershrub with numerous flowers. Root, which is the officinal part, is used in abdominal pain, constipation, calculus, general anasarca, piles, helminthic manifestations, scabies, skin disorders, suppurative ulcers and diseases caused by the morbidity of kapha and pitta. Root paste is applied to painful swellings and piles. Leaves cure asthma and seeds are used in snakebite (Kurup et al, 1979; Sharma, 1983). The drug forms an important constituent of preparations like Dantyarishta, Dantiharitakileham, Kaisoraguggulu gulika, etc.(Sivarajan et al, 1994).

Distribution: The plant is found throughout the sub-Himalayan tracts from Kashmir to Khasi Hills. It is common in West Bengal, Bihar and Central and Peninsular India.

Botany: Baliospermum montanum (Willd.) Muell-Arg. syn. B. axillare Bl., B. polyandrum Wt. belongs to the family Euphrobiaceae. It is a stout under-shrub 0.9-1.8m in height with herbaceous branches from the roots. Leaves are simple, sinuate-toothed, upper ones small, lower ones large and sometimes palmately 3-5 lobed. Flowers are numerous, arranged in axillary racemes with male flowers above and a few females below. Fruits are capsules, 8-13mm long and obovoid. Seeds are ellipsoid smooth and mottled (Warrier et al,1993).

Agrotechnology: The tropical plant is suited to almost all soils. It can be cultivated either as pure crop or intercrop. It is propagated vegetatively by cuttings. About 15-20cm long rooted cuttings are used for planting. Pits of size 50cm cube are to be taken at 3m spacing and filled with dried cowdung, sand and top soil and formed into a mound. On these mounds, rooted cuttings are to be planted at 2 cuttings/mound. Cuttings establish within one month. Weeding is to be carried out at this time. Application of organic manure after every 6 months is beneficial. Irrigation during summer months is preferable. The plant is not attacked by any serious pests or diseases. Roots can be collected at the end of second year. The roots are to be cut and dried in sun before marketing. The yield is about one tonne root/ha (Prasad et al,1997).

Properties and activity: Roots contain diterpenes, baliospermin, montanin, phorbol-12-deoxy-13-O-palmitate, phorbol-12-deoxy-16-hydroxy-13-O-palmitate and phorbol-12-deoxy-5 -hydroxy-13 – myristate (Ogura et al, 1978). Alcoholic extract of plant showed hypotensive activity in experimental animals (Bhakuni et al, 1971). Antilukaemic and cytotoxic activities have been demonstrated in the esters of both 12-deoxyphorbol and 12-deoxy-16-hydroxyphorbol, isolated from B. montanum (King-horn, 1979). The roots are acrid, thermogenic, purgative, antiinflammatory, anodyne, digestive, anthelmintic, diuretic, diaphoretic, rubefacient, febrifuge and tonic. Seed is purgative, stimulant, rubefacient and antidote for snakebite. Seed oil is antirheumatic. Leaf is antiasthmatic and wound healing. Root and seed oil is cathartic and antidropsical. Stem is anti-dontalgic.... nagadanti

Tamarindus Indica

Linn. 643

English: Big Marigold, Aztec or African Marigold.

Ayurvedic: Jhandu, Gendaa.

Unani: Sadbarg, Gul-hazaaraa, Gul-jaafari.

Siddha: Thuruksaamanthi.

Action: Whole plant—infusion useful in cold and bronchitis, also in the treatment of rheumatism.

Flowers—alterative; juice used for bleeding piles. Leaves—styptic, applied externally to boils and carbuncles; muscle pains. Leaves and florets— emengagogue, diuretic, vermifuge.

The flowers gave lutein esters of dipalmitate, dimyristate and mono- myristate. Fresh petals gave hydrox- yflavones, quercetagetin and tagetiin.

The plant yields an essential oil containing limonene, ocimene, linalyl acetate, linalool, tagetone and n-nonyl aldehyde as major components.

The aqueous extract of flowers showed activity against Gram-positive bacteria.

Tagetes mmuta Linn., synonym T. glandulifera Schrank (North-west Himalayas; native to South America), known as Stinking-Roger, gives highest yield of the essential oil with high carbonyl content, calculated as tagetone among the Tagetes sp. grown in India.... tamarindus indica

Abutilon Indicum

Linn. Sweet.

Synonym: A. indicum G. Don.

Family: Malvaceae.

Habitat: Throughout the hotter parts of India. Found as a weed in the sub-Himalayan tract and other hills up to 1,200 m.

English: Country Mallow, Flowering Maples, Chinese Bell-flowers.

Ayurvedic: Atibalaa, Kankatikaa, Rishyaproktaa.

Unani: Kanghi, Musht-ul-Ghaul, Darkht-e-Shaan.

Siddha/Tamil: Thutthi.

Folk: Kanghi, Kakahi, Kakahiyaa.

Action: Dried, whole plant— febrifuge, anthelmintic, demulcent, diuretic, anti-inflammatory (in urinary and uterine discharges, piles, lumbago). Juice of the plant— emollient. Seeds—demulcent (used in cough, chronic cystitis), laxative. Leaves—cooked and eaten for bleeding piles. Flowers— antibacterial, anti-inflammatory. Bark—astringent, diuretic. Root— nervine tonic, given in paralysis; also prescribed in strangury.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of the root in gout, polyuria and haemorrhagic diseases.

The plant contains mucilage, tannins, asparagines, gallic acid and ses- quiterpenes. Presence of alkaloids, leucoanthocyanins, flavonoids, sterols, triterpenoids, saponins and cardiac glycosides is also reported.

Asparagine is diuretic. Gallic acid is analgesic. Mucilages act by reflex, loosen cough as well as bronchial tension. Essential oil—antibacterial, antifungal.

The drug exhibits immunological activity. It augments antibody in animals. EtOH (50%) extract of A. indicum ssp. guineense Borssum, synonym A. asiaticum (Linn.) Sweet, exhibits anticancer activity.

Related sp. include: Abutilon avicen- nae Gaertn., synonym A. theophrastii

Medic.; A. fruticosum Guill. et al.; A. hirtum (Lam.) Sweet, synonym A. graveolens Wt. and Arn.; A. muticum Sweet, synonym A. glaucum Sweet; and A. polyandrum Wight and Arn., synonym A. persicum (Burm. f.) Merrill (known as Naani-khapaat, Jhinaki- khapaat, Kanghi, Makhamali-khapaat and Khaajavani-khapaat, respectively, in folk medicine).

Dosage: Root—3-6 g powder. (API Vol I.)... abutilon indicum

Achyranthes Aspera

Linn.

Family: Amaranthaceae.

Habitat: Throughout the tropical and subtropical regions, up to an altitude of 2,100 m, in the southern Andaman Islands.

English: Prickly Chaff Flower.

Ayurvedic: Apaamaarga, Chirchitaa, Shikhari, Shaikharika, Adahshalya, Mayura, Mayuraka, Kharamanjari, Kharapushpaa, Pratyakpushpaa, Aaghaat, Vashira, Kanihi.

Unani: Chirchitaa.

Siddha/Tamil: Naayuruvi.

Folk: Chirchitta, Chichidaa, Latjeeraa.

Action: Astringent, pectoral (ashes of the plant used in asthma and cough), diuretic, hepatoprotective, emmenagogue. Benzene extract of the plant exhibited abortifacient activity. The flowers, ground and mixed with sugar, are given for menorrhagia. Roots—astringent, haemostatic. Seeds—emetic; used for biliousness. Essential oil— antifungal.

Key application: As astringent, emetic. (Indian Herbal Pharmacopoeia.)

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of the whole plant in lipid disorders and obesity, the root for its blood-purifying property.

The plant juice and ash are used for treating bleeding piles. An alkaline powder of the plant is used in preparing Kshaarasutra of Ayurvedic medicine, which is recommended for treating fistula-in-ano.

The whole plant contains the alkaloids achyranthine and betaine. Achy- ranthine, a water-soluble alkaloid, is reported to dilate blood vessels, lower blood pressure, decrease heart rate and increase the rate and amplitude of respiration. It also shows spasmodic effects on the rectus muscle of frog, diuretic and purgative action in albino rats.

The presence of ecdysterone and oleanolic acid is also reported in the root.

The ashes of the plant yield large quantities of potash. The seeds yield saponins and oleanolic acid and its ester.

The presence of tannins and glyco- sides is also reported in the plant.

Dosage: Whole plant—20-30 g for decoction. Root—5-10 g. (API Vols. II, III.) Ash—500 mg to 2 g. (CCRAS.)... achyranthes aspera

Balanophora Involucrata

Hook. f.

Family: Balanophoraceae.

Habitat: The Himalayas from Kashmir to Sikkim and Darjeeling at altitudes of 1,800-3,400 m

Ayurvedic: Chavya (tentative synonym).

Action: Astringent. Used in piles, also in rheumatism.

A related species, B.polyandra Griff., found in Nagaland, Manipur, West Bengal, Bihar, Orissa and Andhra Pradesh at 2,000 m, gave a phenolic gly- coside, coniferin. The plant is used as an antiasthmatic.... balanophora involucrata

Cucurbits

Cucurbitaceae

The family Cucurbitaceae includes a large group of plants which are medicinally valuable. The important genera belonging to the family are Trichosanthes, Lagenaria, Luffa, Benincasa, Momordica, Cucumis, Citrullus, Cucurbita, Bryonopsis and Corallocarpus. The medicinally valuable species of these genera are discussed below.

1. Trichosanthes dioica Roxb.

Eng: Wild Snake-gourd; San: Meki,Pargavi, Parvara, Patola;

Hin: Palval, Parvar

Ben: Potol;

Mal: Kattupatavalam, Patolam;

Tam: Kombuppudalai;

Tel: Kommupotta

Wild snake-gourd is a slender-stemmed, extensively climbing, more or less scabrous and woolly herb found throughout the plains of N. India, extending to Assam and W. Bengal. Tendrils are 2-4 fid. Leaves are 7.5x5cm in size, ovate-oblong, cordate, acute, sinuate- dentate, not lobed, rigid, rough on both surface and with a petiole of 2cm. Flowers are unisexual. Male flowers are not racemed but woolly outside. Calyx tube is 4.5cm long, narrow, teeth linear and erect. Anthers are free. Fruit is 5.9cm long, oblong or nearly spherical, acute, smooth and orange-red when ripe. Seeds are half-ellipsoid, compressed and corrugated on the margin (Kirtikar and Basu, 1988). The unripe fruit of this is generally used as a culinary vegetable and is considered very wholesome and specially suited for the convalescent. The tender shoots are given in decoction with sugar to assist digestion. The seeds are useful for disorders of the stomach. The leaf juice is rubbed over the chest in liver congestion and over the whole body in intermittent fevers (Nadkarni, 1998). The fruit is used as a remedy for spermatorrhoea. The fresh juice of the unripe fruit is often used as a cooling and laxative adjunct to some alterative medicines. In bilious fever, a decoction of patola leaves and coriander in equal parts is given. The fruit in combination with other drugs is prescribed in snakebite and scorpion sting (Kirtikar and Basu, 1988).

Fruits contain free amino acids and 5-hydroxy tryptamine. Fatty acids from seeds comprise elaeostearic, linoelic, oleic and saturated acids. The aerial part is hypoglycaemic. Leaf and root is febrifuge. Root is hydragogue, cathartic and tonic. Unripe leaf and fruit is laxative (Husain et al, 1992). The plant is alterative and tonic. Leaves are anthelmintic. Flower is tonic and aphrodisiac. The ripe fruit is sour to sweet, tonic, aphrodisiac, expectorant and removes blood impurities.

The other important species belonging to the genus Trichosanthes are as follows.

T. palmata Roxb. T. cordata Roxb. T. nervifolia Linn.

T. cucumerina Linn.

T. anguina Linn.

T. wallichiana Wight. syn. T. multiloba Clarke

2. Lagenaria vulgaris Ser. syn. Cucurbita Lagenaria Linn. ; Roxb.

Eng: Bottle gourd San: Alabu Hin: Lauki, Jangli-khaddu

Ben: Lau, Kodu

Mal: Katuchuram, Churakka

Tam: Soriai-kay

Tel: Surakkaya

Bottle gourd is a large softly pubescent climbing or trailing herb which is said to be indigenous in India, the Molucas and in Abyssinia. It has stout 5-angled stems with bifid tendrils. Leaves are ovate or orbiculate, cordate, dentate, 5-angular or 5-lobed, hairy on both surfaces. Flowers are large, white, solitary, unisexual or bisexual, the males long and females short peduncled. Ovary is oblong, softly pubescent with short style and many ovules. Fruits are large, usually bottle or dumb-bell-shaped, indehiscent and polymorphous. Seeds are many, white, horizontal, compressed, with a marginal groove and smooth. There are sweet fruited and bitter-fruited varieties (Kirtikar and Basu, 1988). The fruit contains a thick white pulp which, in the cultivated variety (kodu) is sweet and edible, while in the smaller wild variety (tamri) it is bitter and a powerful purgative. The seeds yield clear limpid oil which is cooling and is applied to relieve headache. The pulp of the cultivated forms is employed as and adjunct to purgatives and considered cool, diuretic and antibilious, useful in cough, and as an antidote to certain poisons. Externally it is applied as a poultice. The leaves are purgative and recommended to be taken in the form of decoction for jaundice (Nadkarni, 1998). In the case of sweet-fruited variety, the stem is laxative and sweet. The fruit is sweet oleagenous, cardiotonic, general tonic, aphrodisiac, laxative and cooling. In the case of bitter-fruited variety, the leaves are diuretic, antibilious; useful in leucorrhoea, vaginal and uterine complaints and earache. The fruit is bitter, hot, pungent, emetic, cooling, cardiotonic, antibilious; cures asthma, vata, bronchitis, inflammations ulcers and pains.

3. Luffa acutangula (Linn.) Roxb.

Eng: Ridged gourd; San: Dharmargavah, Svadukosataki;

Hin: Tori, Katitori;

Ben: Ghosha

Mal: Peechil, Peechinga;

Tam: Pikangai, Prikkangai;

Tel: Birakaya;

Kan: Kadupadagila

Ridged gourd or ribbed gourd is a large monoecious climber cultivated throughout India. It is with 5-angled glabrous stems and trifid tendrils. Leaves are orbicular-cordate, palmately 5-7 lobed, scabrous on both sides with prominent veins and veinlets. Flowers are yellow, males arranged in 12-20 flowered axillary racemes. Female flowers are solitary, arranged in the axils of the males. Ovary is strongly ribbed. Fruits are oblong-clavate with 10-sharp angles 15-30cm long, tapering towards the base. Seeds are black, ovoid-oblong, much compressed and not winged (Warrier et al, 1995). The leaves are used in haemorrhoids, leprosy, granular-conjunctivitis and ringworm. The seeds are useful in dermatopathy. The juice of the fresh leaves is dropped into the eyes of children in granular conjunctivitis, also to prevent the lids from adhering at night on account of excessive meihomian secretion (Nadkarni, 1998). Fruits are demulcent, diuretic, tonic, expectorant, laxative and nutritive. The seeds are bitter, emetic, cathartic, expectorant and purgative.

The other important species of the genus Luffa are:

L. aegyptiaca Mill.

L. acutangula var. amara Clarke

L. echinata Roxb.

4. Benincasa hispida (Thumb.) Cogn. syn. B. cerifera Savi.

Eng: Ash gourd, White gourd melon; San: Kusmandah;

Hin: Petha, Raksa;

Ben: Kumra

Mal: Kumpalam;

Tam: Pusanikkai;

Kan: Bile Kumbala;

Tel: Bodigummadi

Ash gourd or White gourd melon is a large trailing gourd climbing by means of tendrils which is widely cultivated in tropical Asia. Leaves are large and hispid beneath. Flowers are yellow, unisexual with male peduncle 7.5-10cm long and female peduncle shorter. Fruits are broadly cylindric, 30-45cm long, hairy throughout and ultimately covered with a waxy bloom. The fruits are useful in asthma, cough, diabetes, haemoptysis, hemorrhages from internal organs, epilepsy, fever and vitiated conditions of pitta. The seeds are useful in dry cough, fever, urethrorrhea, syphilis, hyperdipsia and vitiated conditions of pitta (Warrier et al,1993). It is a rejuvenative drug capable of improving intellect and physical strength. In Ayurveda, the fresh juice of the fruit is administered as a specific in haemoptysis and other haemorrhages from internal organs. The fruit is useful in insanity, epilepsy and other nervous diseases, burning sensation, diabetes, piles and dyspepsia. It is a good antidote for many kinds of vegetable, mercurial and alcoholic poisoning. It is also administered in cough, asthma or respiratory diseases, heart diseases and catarrah. Seeds are useful in expelling tapeworms and curing difficult urination and bladder stones. The important formulations using the drug are Kusmandarasayana, Himasagarataila, Dhatryadighrita, Vastyamantakaghrita, Mahaukusmandakaghrita, etc. (Sivarajan et al, 1994).

Fruits contain lupeol, -sitosterol, n-triacontanol, vitamin B, mannitol and amino acids. The fruit is alterative, laxative, diuretic, tonic, aphrodisiac and antiperiodic. Seed and oil from seed is anthelmintic (Husain et al, 1992).

5. Momordica charantia Linn.

Eng: Bitter gourd, Carilla fruit San: Karavellam

Hin: Karela, Kareli

Mal: Kaypa, Paval

Tam: Pavakkai, Paval, Pakar

Tel: Kakara

Bitter gourd or Carilla fruit is a branched climbing annual which is cultivated throughout India. It is a monoecious plant with angled and grooved stems and hairy or villous young parts. Tendrils are simple, slender and elongate. Leaves are simple, orbicular, cordate and deeply divided into 5-7 lobes. Flowers are unisexual, yellow and arranged on 5-10cm long peduncles. Fruits are 5-15cm long with 3-valved capsules, pendulous, fusiform, ribbed and beaked bearing numerous triangular tubercles. Seeds are many or few with shining sculptured surface. The roots are useful in coloptosis and ophthalmopathy. The leaves are useful in vitiated conditions of pita, helminthiasis, constipation, intermittent fever, burning sensation of the sole and nyctalopia. The fruits are useful in skin diseases, leprosy, ulcers, wounds, burning sensation, constipation, anorexia, flatulence, colic, helminthiasis, rheumatalgia, gout, diabetes, asthma, cough, dysmenorrhoea, impurity of breast milk, fever and debility. Seeds are useful in the treatment of ulcers, pharyngodynia, and obstructions of the liver and spleen. The leaves and fruits are used for external application in lumbago, ulceration and bone fractures and internally in leprosy, haemorrhoids and jaundice (Warrier et al, 1995). The drug improves digestion, calms down sexual urge, quells diseases due to pitta and kapha and cures anaemia, anorexia, leprosy, ulcers, jaundice, flatulence and piles. Fruit is useful in gout, rheumatism and complaints of liver and spleen (Nadkarni, 1954; Aiyer and Kolammal, 1966; Mooss, 1976; Kurup et al, 1979). Kaccoradi taila is an important preparation using the drug (Sivarajan et al, 1994).

The seeds give triterpene glycosides, named momordicosides A, B, C, D and E, which are glycosides of cucurbit-5-en-triol, tetraol or pentaol. Leaves and vines give tetracyclic triterpenes-momordicines I, II and III (bitter principles). Immature fruits give several non-bitter and 2 bitter cucurbitacin glycosides. Four of the non-bitter glycosides, momordicosides F1, F2, G and I and the bitter momordicosides; K and L have also been characterized. Fruits, seeds and tissue culture give a polypeptide which contained 17 types of amino acids and showed hypoglycaemic activity. Fruits also give 5-hydroxy tryptamine and a neutral compound charantin (a steroidal glucoside), diosgenin, cholesterol, lanosterol and -sitosterol. Leaf is emetic, purgative and antibilious. Fruit is stomachic, tonic, carminative, febrifuge, antirheumatic and hypoglycaemic. Root is astringent. Fruit and leaf is anti-leprotic. Fruit, leaf and root are abortifacient and anti-diabetic. Leaf and seed is anthelmintic. Seed oil possesses antifeeding and insecticidal properties. Unsaponifiable matter from seed oil exhibited pronounced inhibitory activity against gram negative bacteria. Seed and fruit are hypoglycaemic, cytotoxic and anti-feedant (Husain et al, 1992).

Other important species belonging to the genus Momordica are as follows.

M. dioica Roxb.

M. cochinchinensis Spreng.

M. tuberosa Cogn.

M. balsamina Linn.

6. Cucumis melo Linn. syn. C. melo Linn. var. cultis Kurz., C. pubescens

Willd., C. callosus (Rottl.) Cogn.

Eng: Sweet melon San,

Hin: Kharbuja

Ben: Kharmul

Mal: Mulam

Tam: Chukkari-kai, Thumatti-kai, Mulampazham

Tel: Kharbuja-doshavSweet melon is a creeping annual extensively cultivated throughout India, found wild in India, Baluchistan and tropical Africa. The stem is creeping, angular and scabrous. Leaves are orbicular-reniform in outline, 5-angled or lobed, scabrous on both surfaces and often with soft hairs. Lobes of leaves are not very deep nor acute and with 5cm long petiole. Female peduncle is 5cm. Fruit is spherical, ovoid, elongate or contorted, glabrous or somewhat hairy, not spinous nor tuberculate.

Cucumis melo includes two varieties, namely,

C. melo var. momordica syn. C. momordica Roxb.

C. melo var. utilissimus Duthie & Fuller. syn. C. utilissimus Roxb.

The fruit is eaten raw and cooked. Its pulp forms a nutritive, demulcent, diuretic and cooling drink. It is beneficial as a lotion in chronic and acute eczema as well as tan and freckles and internally in cases of dyspepsia. Pulp mixed with cumin seeds and sugar candy is a cool diet in hot season. Seeds yield sweet edible oil which is nutritive and diuretic, useful in painful discharge and suppression of urine. The whole fruit is useful in chronic eczema (Kirtikar & Basu, 1988).

Seeds contain fatty acids-myristic, palmitic, oleic, linoleic; asparagine, glutamine, citrulline, lysine, histidine, arginine, phenylalanine, valine, tyrosine, leucine, iso-leucine, methionine, proline, threonine, tryptophan and crystine. Seed is tonic, lachrymatory, diuretic and urease inhibitor. Fruit pulp is eczemic. Fruit is tonic, laxative, galactagogue, diuretic and diaphoretic. The rind is vulnerary (Husain et al, 1992).

7. Cucumic sativus Linn.

Eng: Cucumber, Common cucumber; San: Trapusah;

Hin,

Ben: Khira;

Mal: Vellari

Tam: Vellarikkai, Pippinkai;

Kan: Mullusavte;

Tel: Dosekaya

Cucumber is a climbing annual which is cultivated throughout India, found wild in the Himalayas from Kumaon to Sikkim. It is a hispidly hairy trailing or climbing annual. Leaves are simple, alternate, deeply cordate, 3-5 lobed with both surfaces hairy and denticulate margins. Flowers are yellow, males clustered, bearing cohering anthers, connective crusted or elevated above the cells. Females are solitary and thickly covered with very bulbous based hairs. Fruits are cylindrical pepo of varying sizes and forms. Seeds are cream or white with hard and smooth testa. The fruits are useful in vitiated conditions of pitta, hyperdipsia, burning sensation, thermoplegia, fever, insomnia, cephalgia, bronchitis, jaundice, haemorrhages, strangury and general debility. The seeds are useful in burning sensation, pitta, constipation, intermittent fevers, strangury, renal calculus, urodynia and general debility (Warrier et al, 1994). The leaves boiled and mixed with cumin seeds, roasted, powdered and administered in throat affections. Powdered and mixed with sugar, they are powerful diuretic (Nadkarni, 1998). The fruits and seeds are sweet, refrigerant, haemostatic, diuretic and tonic. Other important species belonging to the genus are:

C. trigonus Roxb. syn. C. pseudo-colocynthis

C. prophetarum Linn.

8. Citrullus colocynthis (Linn.) Schrader. syn. Cucumis colocynthis Linn.

Eng: Colocynth, Bitter apple; San: Visala, Mahendravaruni;

Hin: Badi indrayan, Makkal

Ben: Makhal;

Mal: Kattuvellari (Valutu), Valiya pekkummatti;

Tel: Etti-puchcha

Tam: Paitummatti, Petummatti;

Colocynth or Bitter apple is found, cultivated and wild, throughout India in warmer areas. It is an extensively trailing annual herb with bifid tendrils angular branching stems and wooly tender shoots. Leaves are deeply divided, lobes narrow thick, glabrous or somewhat hairy. Flowers are unisexual, yellow, both males and females solitary and with pale-yellow corolla. Fruit is a globose or oblong fleshy indehiscent berry, 5-7.5cm in diameter and variegated with green and white. Seeds are pale brown. The fruits are useful in tumours, ascites, leucoderma, ulcers, asthma, bronchitis, urethrorrhea, jaundice, dyspepsia, constipations, elephantiasis, tubercular glands of the neck and splenomegaly (Warrier et al, 1994). It is useful in abnormal presentations of the foetus and in atrophy of the foetus. In addition to the above properties, the root has a beneficial action in inflammation of the breasts, pain in the joints; externally it is used in ophthalmia and in uterine pains. The fruit and root, with or without is rubbed into a paste with water and applied to boils and pimples. In rheumatism, equal parts of the root and long pepper are given in pill. A paste of the root is applied to the enlarged abdomen of children (Kirtikar and Basu, 1988). The fruit is useful in ascites, biliousness, jaundice, cerebral congestion, colic, constipation dropsy, fever, worms and sciatica. Root is given in cases of abdominal enlargement, cough, asthma, inflammation of the breast, ulcers, urinary diseases and rheumatism. Oil from seeds is used for poisonous bites, bowel complaints, epilepsy and also for blackening the hair (Nadkarni, 1954; Dey, 1980). The important formulations using the root and fruit are Abhayarista, Mahatiktakam kasaya, Manasamitravatakam, Cavikasava, Madhuyastyadi taila, etc. (Sivarajan et al, 1994). The powder is often used as an insecticide. The extract should never be given without some aromatic to correct its griping tendency (Nadkarni, 1998).

Fruit contains a glycoside- colocynthin, its aglycone- -elaterin, citrulluin, citrullene and citrullic acid. Unripe fruit contains p-hydroxy benzyl methyl ester. Roots contain - elaterin and hentriacontane (Husain et al, 1992). Colocynth is, in moderate doses, drastic, hydrogogue, cathartic and diuretic. In large doses, it is emetic and gastro-intestinal irritant and in small doses, it is expectorant and alterative. Colocynthin is a cathartic and intensely bitter principle. It has a purgative action. All parts of the plant are very bitter. The fruit has been described as cathartic (Nadkarni, 1982).

9. Citrullus vulgaris Schrad. syn. C. lanatus (Thunb.) Mats. & Nakai.

Eng: Water melon; San: Tarambuja;

Hin: Tarbuj;

Ben: Tarbuz

Mal: Thannimathan;

Tam: Pitcha, Dharbusini

Watermelon is an extensively climbing annual which is largely cultivated throughout India and in all warm countries. It has thick angular branching stems. Tendrils are bifid, stout and pubescent. Leaves are long, deeply divided or moderately lobed, glabrous or somewhat hairy and hardly scabrous. Petiole is a little shorter than the limb and villous. Calyx-lobes are narrowly lanceolate, equalling the tube. Corolla is yellow within, greenish outside and villous. Lobes are ovate-oblong, obtuse and prominently 5-nerved. Fruit is sub-globose or ellipsoid, smooth, greenish or clouded, often with a glaucous waxy coating. Flesh is juicy, red or yellowish white. Seeds are usually margined. C. vulgaris var. fistulosus Duthie & Fuller. syn. C. fistulosus has its fruit about the size of small turnip, the seeds of which are used medicinally. The fruit is tasteless when unripe and sweet when ripe. The unripe fruit is used to cure jaundice. Ripe fruit cures kapha and vata and causes biliousness. It is good for sore eyes, scabies and itching. The seeds are tonic to the brain and used as a cooling medicine. An emulsion of the seeds is made into a poultice with the pounded leaves and applied hot in cases of intestinal inflammations (Kirtikar and Basu, 1988). Fruit juice is good in quenching thirst and it is used as an antiseptic in typhus fever with cumin and sugar. It is used as a cooling drink in strangury and affections of urinary organs such as gonorrhoea; in hepatic congestion and intestinal catarrh. The bitter watermelon of Sind is known as “Kirbut” and is used as a purgative.

Seeds yield a fixed oil and proteids; citrullin. Seeds are cooling, demulcent, diuretic, vermifuge and nutritive. Pulp is cooling and diuretic. Fruit-juice is cooling and refreshing (Nadkarni, 1982).

10. Curcurbita pepo Linn. syn. Pepo vulgaris et P. verrucosus Moench

Meth.

Eng: Pompion, Pumpkin, Vegetable Marrow; San: Karkaru, Kurkaru, Kushmandi

Hin,

Ben: Kadimah, Konda, Kumra, Safedkkadu;

Mal: Mathan, Matha

Tel: Budadegummadi, Pottigummadi

Pompion or Pumpkin is a climbing herb which is considered to be a native of America and cultivated in many parts of India. The stem and leaves are with a harsh prickly armature. Foliage is stiff, more or less rigid and erect. Leaves are with a broad triangular pointed outline and often with deep lobes. Corolla is mostly with erect or spreading (not drooping) pointed lobes, the tube narrowing towards the base. Peduncle is strongly 5-angled and little or much expanding near the fruit. The fruit is cooling and astringent to the bowels, increases appetite, cures leprosy, ‘kapha and vata’, thirst, fatigue and purifies the blood. The leaves are used to remove biliousness. Fruit is good for teeth, throat and eyes and allays thirst. Seeds cure sore chests, haemoptysis, bronchitis and fever. It is good for the kidney and brain. The leaves are used as an external application for burns. The seeds are considered anthelmintic. The seeds are largely used for flavouring certain preparations of Indian hemp, and the root for a nefarious purpose, viz., to make the preparation more potent. The seeds are taeniacide, diuretic and demulcent. The fruit is cooling, laxative and astringent. The leaves are digestible, haematinic and analgesic.

The other important species belonging to the genus Cucurbita is C. maxima Duchena, the seeds of which are a popular remedy for tape-worm and oil as a nervine tonic (Kirtikar & Basu, 1988).

11. Corallocarpus epigaeus Benth. ex Hook. f. syn. Bryonia epigaea Wight.

San: Katunahi;

Hin: Akasgaddah;

Mal: Kadamba, Kollankova

Tam: Akashagarudan, Gollankovai;

Tel: Murudonda, Nagadonda

Corallocarpus is a prostrate or climbing herb distributed in Punjab, Sind, Gujarat, Deccan, Karnataka and Sri Lanka. It is monoecious with large root which is turnip-shaped and slender stem which is grooved, zigzag and glabrous. Tendrils are simple, slender and glabrous. Leaves are sub-orbicular in outline, light green above and pale beneath, deeply cordate at the base, angled or more or less deeply 3-5 lobed. Petiole is long and glabrous. Male flowers are small and arranged at the tip of a straight stiff glabrous peduncle. Calyx is slightly hairy, long and rounded at the base. Corolla is long and greenish yellow. Female flowers are usually solitary with short, stout and glabrous peduncles. Fruit is stalked, long, ellipsoid or ovoid. Seeds are pyriform, turgid, brown and with a whitish corded margin. It is prescribed in later stages of dysentery and old veneral complaints. For external use in chronic rheumatism, it is made into a liniment with cumin seed, onion and castor oil. It is used in case of snakebite where it is administered internally and applied to the bitten part. The root is given in syphilitic rheumatism and later stages of dysentery. The plant is bitter, sweet, alexipharmic and emetic. The root is said to possess alterative and laxative properties (Kirtikar and Basu, 1988). Root contains a bitter principle like Breyonin (Chopra et al, 1980).

Agrotechnology: Cucurbits can be successfully grown during January-March and September- December. For the rainfed crop, sowing can also be started after the receipt of the first few showers.

Pits of 60cm diameter and 30-45cm depth are to be taken at the desired spacing. Well rotten FYM or vegetable mixture is to be mixed with topsoil in the pit and seeds are to be sown at 4-5/pit. Unhealthy plants are to be removed after 2 weeks and retained 2-3 plants/pit. FYM is to be applied at 20-25t/ha as basal dose along with half dose of N (35kg/ha) and full dose of P (25kg) and K (25kg). The remaining dose of N (35kg) can be applied in 2 equal split doses at fortnightly intervals. During the initial stages of growth, irrigation is to be given at an interval of 3-4 days and at alternate days during flowering and fruiting periods. For trailing cucumber, pumpkin and melon, dried twigs are to be spread on the ground. Bitter gourd, bottle gourd, snake gourd and ash gourd are to be trailed on Pandals. Weeding and raking of the soil are to be conducted at the time of fertilizer application. Earthing up may be done during rainy season. The most dreaded pest of cucurbits is fruit flies which can be controlled by using fruit traps, covering the fruits with polythene, cloth or paper bags, removal and destruction of affected fruits and lastly spraying with Carbaryl or Malathion 0. 2% suspension containing sugar or jaggery at 10g/l at fortnightly intervals after fruit set initiation. During rainy season, downy mildew and mosaic diseases are severe in cucurbits. The former can be checked by spraying Mancozeb 0.2%. The spread of mosaic can be checked by controlling the vectors using Dimethoate or Phosphamidon 0.05% and destruction of affected plants and collateral hosts. Harvesting to be done at least 10 days after insecticide or fungicide application (KAU,1996).... cucurbits

Holostemma

Holostemma ada-kodien

Asclepiadaceae

San: Jivanti;

Hin: Chirvel, Charivel;

Mal: Atapathiyan, Atapotiyan, Atakotiyan;

Tam: Palaikkirai;

Tel: Palagurugu; Mar: Dudurli, Shidodi;

Guj: Kharner, Khiravel

Importance: Holostemma is a twining shrub with large flowers. The roots of Holostemma are useful in ophthalmopathy, orchitis, cough, burning sensation, stomachalgia, constipation, fever and tridoshas. The leaves, flowers and fruits are eaten as vegetable. The root is also used in spermatorrhoea. It is used in preparations of Vidaryadiganam, Dhanwandharam thaila, Manasamithravatakam, Balarishta and Anuthaila. It is also useful in eye diseases and it imparts resistance to diseases.

Distribution: The plant occurs in tropical countries. In India, it is found in Himalayas, Dehradun, Konkan, Bombay, Deccan, Karnataka, Kerala and Tamilnadu. It grows over hedges and in open forests especially on the lower slopes of the hills. It is also distributed in Sri Lanka, Burma and W. China.

Botany: Holostemma ada-kodien Schult. syn. Holostemma annulare (Roxb.) K. Schum.

Holostemma rheedii Wall. belongs to the family Asclepiadaceae. It is a laticiferous twining shrub with large conspicuous flowers. Leaves are simple, opposite and cordate. Flowers are purple, arranged in axillary umbellate cymes. Fruits are thick follicles, 9 cm long, cylindrical and bluntly pointed. The roots are long upto 1 m or more, irregularly twisted, thick and cylindrical. When dry it is yellowish brown to brown black in colour with nearly smooth surface bearing white scars and small depressions. A mature root is about 1-2 cm thick when extracted for use (Warrier et al, 1995).

Agrotechnology: Holostemma prefers a tropical climate. The plant is propagated vegetatively by stem cuttings, but mainly by seeds. The seeds are collected from the plant in November-December before being dispersed. Seeds are cleaned, dried and stored for sowing. The stored seeds after soaking in water for 4-5 hours are sown in the seedbeds. About one month old seedlings are then planted in polybags of size 14x10cm which are filled with soil, sand and dried cowdung in 1:1:1 ratio, respectively. Polybags should be kept in shade and irrigated. About 1-1.5 month old seedlings are ready for transplanting. Pits of 30cm cube size are taken at 1-1.2m distance and filled with 10kg dried cowdung and sand. This is covered with surface soil and formed into a mound. Seedlings are transplanted on to the mounds from the polybags carefully. Regular irrigation is to be given till flowering. To aid in trailing, staking is given one month after planting. Flowering and fruiting occurs in November-December. Harvesting can be done at the end of second year when the vines start drying up. Harvesting is done by digging up the tubers. The tubers are cut into pieces of 10cm length and dried in sun before sale (Prasad et al, 1997).

Properties and activity: Holostemma tubers give -amyrin, lupeol and -sitosterol. Alanine, aspartic acid, glycine, serine, threonine and valine were detected chromatographically (Hussain et al, 1992). The root is antidiabetic, antigonorrhoeic, bechic, alterative, tonic, lactative, ophthalmic, emollient, stimulant, aphrodisiac, expectorant and galactagogue.

BLACH MUSALE Curculigo orchioides Amaryllidaceae

San: Musali;

Hin: Kalimusali, Mushali;

Ben: Talamuli;

Mal: Nilappana;

Guj: Musalikand

Tam: Nilapanai;

Tel: Nelatadi Kelangu;

Kan: Neladali

Importance: Musali is a small, geophilous herb, the tuberous rootstock of which is used as a rejuvenating and aphrodisiac drug. It cures morbid vata and pitta, improves complexion and is useful in general debility, deafness, cough, asthma, piles, skin diseases, impotence, jaundice, urinary disorders, leucorrhoea and menorrhagia (Nadkarni, 1954; Aiyer and Kolammal, 1963; Mooss, 1978). Rootstock is the officinal part and it enters into the Ayurvedic formulations like Vidaryadighrta, Vidaryadi lehya, Marmagulika, Musalyadi churna etc. The Pharmacognosy of C. orchioides has been discussed by Aiyer, Kolamma l (1963), Raghunathan, and Mitra (1982). A bibliographical study on C. orchioides has been done by Pandey et al (1983).

Distribution: The plant is found in all districts of India from near sea level to 2300m altitude, especially in rock crevices and laterite soil. It has been recorded to occur in the sub tropical Himalayas from Kumaon eastwards ascending to 1800m, the Khasia hills, Bengal, Asssam, Konkan, Kanara, the western peninsula and Madras extending south as far as a Cape Comerin. It is also distributed in Sri Lanka, Japan, Malaysia and Australia.

Botany: Curculigo orchioides Gaertn. syn. C. malabarica Wight, C. brevifolia Dryand, Hypoxis dulcis Stand belongs to the family Amaryllidaceae. Musali is a small herbaceous plant with cylindrical rootstock. Leaves are simple, sessile, crowded on the short stem with sheathing leaf bases. Flowers are bright yellow. Seeds are black, deeply grooved in wavy lines.

A detailed description of the plant is as follows (Victoria, 1998). Rootstock is straight, cylindrical, tuberous, 5-22cm long, 0.5-0.8 cm thick, brownish surfaces marked with closely spaced prominent transverse wrinkles in the upper or basal half. It bears a few stout lateral roots of 5 or more cm long. Lateral roots are dull white in colour and spongy externally. The fresh cut surfaces of the rootstock has a starch white colour and mucilaginous. A few fibrous roots also occur. Leaves are sessile or short petiolate with sheathing bases, 15-45x1.2-2.5 cm size, linear or linear lanceolate, membranous, glabrouus or sparsely sofly hairy and plicate in bud. The leaf tips when contacts the soil, develops roots and produce adventitious buds. Inflorescence is axillary, scapose racemose, the scape very short and hidden among the bases of leaves underground, clavte, flattened with the pedicels, bracts and the ovary concealed in the leaf sheaths. The lower big flowers on the scape are mostly bisexual and the upper small ones staminate. Flowers are epigynous bright yellow, bisexual or unisxual with lanceolate, memb ranous bract.. Perianth gamophyllous, rotate & six lobed, locate at the top of a slender sterile long extension of the ovary by means of which the perianth is exposed above the ground. Perianth lobes similar, elliptic oblong 1.2-1.6 cm long, 0.2-0.3 cm broad, outer lobes hairy on the back, inner ones sparsely hairy along nerves. Stamens 6 in number, filamentous filiform, short 2mm long, adnate to the base of the perianth lobes, Anthers linear or linear lanceolate, basifixed and sagittate,.Ovary inferior, hidden among the leaves usually below the ground, tricarpellary syncarpous, lanceolate and trilocular with a fairly long slender beak or extension -the stipe. Ovules many in each cell attached by a distinct long funicle. Style short columnar, 2mm with a 3 lobed stigma. Lobes elongate, erect and appressed. Fruit is a capsule about 1.5-2cm long, 8mm broad, oblong, glabrescent with a slender beak and spongy septa. Seeds 1-many, oblong, black, shiny with crustaceous testa grooved deeply in wavy lines.

Properties and activity: Rao and Beri (1951) have identified glucose, mannose, xylose and glucuronic acid from the rootstock of C. orchioides. The rootstock is also reported to contain glycoside, polysaccharides (hemicellulose and other polysaccharides), starch, resin, tannin, mucilage, fat and calcium oxalate. The hexane extract contains an alkaloid-lycorine, sterols including -sitosterols and sapogenin identified as yuccagenin (Rao et al, 1978). The flavone glycoside from the rootstock has been identified as 5,7- dimethoxy glucopyranoside (Yadav et al, 1974; Sharma et al 1975). Mehta et al (1980) have isolated a number of fatty acids from C. orchioides root oil by GLC techniques. They are palmitic, oleic, linolenic linoleic, arachidic and behenic acid. Kubo et al (1983) isolated a new phenolic glycoside namely, curculigoside from the rhizomes and its structure has been elucidated as 5- hydroxy-2-0- -d-glucopyranosyl benzl 1,2,6-dimethoxy benzoate. Yamasaki et al (1994) developed HPLC method for estimating the curculigoside content in curculigo rhizome.

Two new aliphatic hydroxy ketone 27-hydroxy tricontan-6-one (M. P. 84-85o C) and 23- hydroxy tricontan-2-one (M. P. 109-110 o C) were isolated from the rhizome by Misra et al (1984). They also isolated 21-hydroxy tetracontan-20-one and 4-methyl heptade canoic acid from the root stock. Porwal et al (1988) have isolated and identified three new compounds from the rhizome as N- acetyl-N-hydroxy-2-carbamic acid methyl ester, 3-acetyl-5-carbomethoxy-2H-3,4,5,6-tetrahydro-1,2,3,5,6-oxatetrazine and N, N, N’, N’-tetra methyl succinamide. The rhizomes of C. orchioides yielded a new phenolic glycoside corchioside a, characterised as orcinol-3- -D-xylopyranosyl- (1 6)- -D-glucopyranoside and hentriacontanol (Garg et al, 1989).

A new aliphatic compound has been isolated from the rhizomes and characterised as 25- dihydroxy-33-methyl pentatricontan-one (Mehta et al, 1990). Misra et al (1990) isolated a new natural triterpene alcohol-Curculigol charactrised as 24-methy cycloart-7-en-3-beta-20-diol. A novel pentacyclic triterpene has been isolated from the rhizomes of C.orchioides and characterised as 31- methyl-3-oxo-20-ursen-28-oic acid (Metha and Gawarikar,1991). Xu and Xu (1992) and Xu et al (1992 a, b) have isolated 13 cycloartane type. Triterpene glycosides from C. orchioides rhizome and characterised them as curculigo saponin A-M.

The root stock are mucilaginous, sweet, cooling, bitter, emollient, diuretic, aphrodisiac, depurative, alternative, appetiser, carminative, viriligenic, antipyretic and tonic (Sivarajan and Indira, 1994; Warrier et al, 1994).

The uterine stimulant activity of the flavone glycoside extracted from C. orchioides has been studied by Dhawan and Saxena (1958), Sharma et al (1975) and Dhar et al (1979).

The plant extract of C. orchioides showed hypoglycaemic, spasmolytic and anticancer properties (Dhar et al,1968). Phagocytic activity (Kubo et al, 1983) and immunoadjuvant activity (Oru et al, 1982) of phenolic glycosides, curculigoside isolated from the rhizome of the plant have been reported. Porwal and Mehta (1985) discussed the medicinal importance of the plant and its use in indigenous system of medicine as a tonic. Sharma et al (1991) reported the influence of MAK an ayurvedic food supplement constituting C. orchioides against Dimethyl benz anthracene induced mammary tumours in rats. Samanta (1992) reported the modulation of male infertility by Ayurvedic drug, which constitutes C. orchioides. Immunostimulant activity of C. orchioides has been demonstrated by Saxena (1992). Immunological activites of curculigo saponin G were assayed in mice and the results showed that it promoted proliferation of spleen lymphocyctes very significantly and increased the weight of the thymus in vivo in mice (Xu et al,1992).

Pharmacological studies in China, on the alcoholic extract obtained from the plant showed several active effects such as adaptogenic, anti-inflammatory, anticonvulsant, sedative, androgenic and immunopromoting activities (Xu et al, 1992).

Curculigo orchioides is distributed widely throughout the country. The demand of the raw materials and derivatives of the plant for the indigenous drug industries are satisfied mainly from the wild source, depleting the natural population and thus the species have become extinct or endangered. Ansari (1993) have reported C. orchioides as a threatened plant from Madhulia forest of Garakhpur. Augustin and Souza (1995) also considered the plant as an endangered species. As the information on the cultivation of C.orchioides is scanty, it is very necessary to develop suitable agrotechniques for the domestication and large-scale cultivation of the plant.... holostemma

Kedrostis Foetidissima

(Jacq.) Cogn.

Synonym: K. rostrata (Rottl.) Cogn. Bryonia rostrata Rottl. Rhynghocarpa foetida Clarke

Family: Cucurbitacease.

Habitat: Gujarat, Madhya Pradesh, Maharashtra, Andhra Pradesh and Tamil Nadu.

Folk: Appakovay (Tamil Nadu). Kukumadona, Nagadonda (Andhra Pradesh) Nurakvel (Maharashtra).

Action: Root and fruit—demulcent; used in asthma and piles.... kedrostis foetidissima

Albizia Lebbeck

(Linn.) Willd.

Family: Mimosaceae.

Habitat: All over India, from the plains up to 900 m in the Himalayas; also in the Andamans.

English: Siris tree, East Indian walnut.

Ayurvedic: Shirisha, Bhandi, Bhandila, Shitapushpa, Mridu- pushpa, Kapitana (bark—dusty black).

Unani: Siras.

Siddha/Tamil: Vaagei.

Action: Antiseptic, antibacterial, antiallergic, antidermatosis, antidysenteric. Bark—used in bronchitis; bark and seeds in piles; root in hemicrania; flowers in cough, bronchitis, tropical pulmonary eosinophilia, and asthma. Pod— antiprotozoal.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of stembark in rhinitis, sinusitis and migraine.

Analysis of the plant revealed the presence of flavonoids, triterpenoids and triterpenoid saponins; oleano- lic acid, albigenic acid, albigenin and acacic acid. The bark contains 7-11% condensed tannin; also d-catechin and d-leucocyanidin.

Aqueous extract of the bark decreased histamine-induced broncho- spasm in guinea pigs.

Alcoholic extract of stembark contains cardenolide glycosides of digitox- in nature. It showed antidermatophyt- ic activity. Anthraquinone glycosides and its aglycone exhibited antibacterial activity.

A saponin from seeds exhibited spermicidal activity in animals. EtOH (50%) extract of pods was found to be spermicidal against rat and human spermatozoa at 2% concentration.

The therapeutic properties of Albizia julibrissin Durazz, Pink Siris, found in the outer Himalayas from the Indus eastwards to Sikkim, are the same as those of A. lebbeck.

Dosage: Stembark—3-6 g powder.

20-50 g for decoction. (API

Vol. III.)... albizia lebbeck

Alhagi Pseudalhagi

(Bieb.) Desv.

Synonym: A. camelorum Fisch. ex DC.

A. maurorum Medic.

Family: Papilionaceae; Fabaceae.

Habitat: The drier parts of Rajasthan, Gujarat, Punjab and Uttar Pradesh.

English: Camel Thorn, Persian Manna Plant.

Ayurvedic: Yavaasaka, Yavaasa, Yaasa, Duhsparshaa, Duraalab- haa, Kunaashak. Substitute for Dhanvayaasa. Yaasa-sharkaraa (Alhagi-manna).

Unani: Jawaansaa. Turanjabeen (Alhagi-manna).

Siddha/Tamil: Punaikanjuri, Kan- chori.

Action: Laxative, antibilious, diuretic, diaphoretic, expectorant. Leaves—used for fever, headache, rheumatism. Flowers—blood coagulant, used for piles. Alhagi- manna—expectorant, antiemetic, laxative.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of dried whole plant in gout and haemorrhagic disorders.

The aerial parts contain flavonoids, tannins, sterols, triterpenes, saponins and anthroquinones.

The proanthocyanidins derived from the plant possess hypolipidemic and antiatherosclerotic properties. The compounds prevented an increase in rat serum cholesterol and triglycerides, and they decreased the manifestation of atherosclerosis.

A polymeric proanthocyanidin, extracted from the plant, improved energy metabolism and increased the work capacity in rats.

Ethanolic extract of the aerial parts produced positive inotropic effect on rabbit heart.

Dosage: Whole plant—20-50 g for decoction. (API Vol. II.) Decoction—50-100 ml. (CCRAS.)... alhagi pseudalhagi

Amaranthus Caudatus

Linn.

Family: Amaranthaceae.

Habitat: Grown as vegetable in northern India.

English: Love-Lies-Bleeding, Tassel Flower.

Ayurvedic: Raam-daanaa (grain).

Siddha/Tamil: Pungikeerai, Siru- keerai.

Folk: Chuko.

Action: Blood-purifier, diuretic; used in piles, strangury, dropsy and anasarca; tea has been used for relieving pulmonary conditions; also given in scrofula and applied to scrofulous sores. Antimicrobial peptides have been isolated from seeds.

In Western herbal medicine, LoveLies-Bleeding is equated with Amaranthus hypochondriacus, and is used for ulcers, diarrhoea, as well as inflammation of the mouth and throat.

Preliminary evidence suggests that Amaranth seed can reduce total cholesterol and LDL, while increasing HDL, but Amaranth muffins failed to reduce cholesterol levels in hypercholes- terolemic adults beyond the reduction achieved by low-fat diet. (Natural Medicines Comprehensive Database, 2007.)... amaranthus caudatus

Long Pepper

Piper longum

Piperaceae: San: Pippali;

Hin, Ben, Pun: Piplamul; Kan, Mal:Thippali ;

Tam: Thippili; Mar: Pimpli;

Tel: Pipppaloo; Ass: Piplu.

Introduction: Long pepper is a slender aromatic climber whose spike is widely used in ayurvedic and unani systems of medicine particularly for diseases of respiratory tract. Pipalarishta, Pippalyasava, Panchakola, Pippalayadilauha, and Lavana bhaskar churan are common ayurvedic preparations made out of the dry spikes of female types. Ittrifal fauladi, Angaruya-i-kabir and Majun khadar are well known unani preparations of long pepper. Its roots also have several medicinal uses. The root is useful in bronchitis, stomach ache, diseases of spleen and tumours. Fruit is useful in vata and kapha, asthma, bronchitis, abdominal complaints, fever, leucoderma, urinary discharges, tumours, piles, insomnia and tuberculosis. Root and fruit are used in gout and lumbago. The infusion of root is prescribed after parturition to induce the expulsion of placenta. The root and fruit decoction are used in acute and chronic bronchitis and cough. It contains the alkaloid piperine which has diverse pharmacological activities, including nerve depressant and antagonistic effect on electro- shock and chemo -shock seizures as well as muscular incoordination.

Distribution: The plant is a native of Indo-Malaya region. It was very early introduced to Europe and was highly regarded as a flavour ingredient by the Romans. The Greek name “Peperi”, the Latin “Piper” and the English “Pepper” were derived from the Sanskrit name “Pippali”. It grows wild in the tropical rain forests of India, Nepal, Indonesia, Malaysia, Sri lanka, Rhio, Timor and the Philippines. In India, it is seen in Assam, West Bengal, Uttar Pradesh, Madhya Pradesh, Maharashtra, Kerala, Karnataka.and Tamil Nadu. It is also cultivated in Bengal, Chirapunchi area of Assam, Akola-Amravati region of Maharashtra, Anamalai hills of Tamil Nadu, Orissa, Uduppi and Mangalore regions of Karnataka. Bulk of Indian long pepper comes from its wild growth in Assam, Shillong and West Bengal, supplemented by imports from Sri Lanka and Indonesia (Viswanathan,1995)

Botany: Piper longum Linn. is a member of Piperaceae family. The plant is a glabrous perennial under-shrub with erect or sub-scandent nodose stem and slender branches, the latter are often creeping or trailing and rooting below or rarely scandent reaching a few metres height. Leaves are simple, alternate, stipulate, and petiolate or nearly sessile; lower ones broadly ovate, cordate; upper ones oblong, oval, all entire, smooth, thin with reticulate venation; veins raised beneath. It flowers nearly throughout the year. Inflorescence is spike with unisexual small achlamydeous densely packed flowers and form very close clusters of small greyish green or darker grey berries. Female spikes with short thick stalk varying from 1.5 to2.5 cm in length and 0.5 to 0.7 cm in thickness.

A number of geographical races are available in different agroclimatic regions of India; the most popular being Assam, West Bengal and Nepal races. Piper officinarum DC; syn. Chavica officinarum Miquel, Piper pepuloides and Piper chaba Hunter are the other related species of importance.

Agrotechnology: Long pepper is a tropical plant adapted to high rainfall areas with high humidity. An elevation of 100-1000 m is ideal. It needs partial shade to the tune of 20-30% for best growth. The natural habitat of the plant is on the borders of streams. It is successfully cultivated in well drained forest soils rich in organic matter. Laterite soils with high organic matter content and moisture holding capacity are also suitable for cultivation.

Long pepper is propagated by suckers or rooted vine cuttings.15-20 cm long 3-5 nodded rooted vine cuttings establishes very well in polybags. The best time for raising nursery is March-April. Normal irrigation is given on alternate days. The rooted cuttings will be ready for transplanting in 2 months time. With the onset of monsoon in June the field is ploughed well and brought to good tilth. 15-20 cm raised beds of convenient length and breadth are taken. On these beds, pits are dug at 60 x 60 cm spacing and well decomposed organic manure at 100 g/pit is applied and mixed with the soil. Rooted vine cuttings from polybags are transplanted to these pits. Gap filling can be done after one month of planting.The crop needs heavy manuring at the rate of 20 t FYM/ha every year. Application of heavy dose organic matter and mulching increase water retention in the soil and control weeds. Small doses of chemical fertilisers can also be used. The crop needs irrigation once a week. Sprinkler irrigation is ideal. With irrigation the crop continues to produce spikes and off-season produce will be available. However, it is reported that unirrigated crop after the onset of monsoon grows vigorously and shows much hardiness than the irrigated crop.

Crop losses can be heavy due to pests and diseases. Mealy bugs and root grubs, attack the plant particularly during summer. Infested plants show yellowing and stunted growth. Application of systemic insecticides like nuvacron or dimecron will control the pests. Adults and nymphs of Helopeltis theivora severely feeds on the foliage which can be controlled by 0.25% neem kernel suspension. Rotting of leaves and vines during monsoon season is caused by Colletotrichum glorosporiodes and necrotic lesions and blights on the leaves during summer is caused by Colletotrichum and Cercospora spp. These diseases can be controlled by spraying of 1% Bordeaux mixture repeatedly. A virus like disease characterised by yellowing and crinkling of leaves, stunted growth and production of spikes of smaller size and inferior quality was also recently reported.

The vines start flowering six months after planting and flowers are produced almost throughout the year. The spikes mature in 2 months time. The optimum stage of harvest is when the spikes are blackish green. The pungency is highest at this stage. Spikes are hand picked when they become mature and then dried. The yield of dry spike is 400 kg /ha during first year, increases to 1000kg during third year and thereafter it decreases. Therefore, after 3 years the whole plant is harvested. The stem is cut close to the ground and roots are dug up. Average yield is 500 kg dry roots/ha (Viswanathan,1995).

Piper longum can also be cultivated as an intercrop in plantations of coconut, subabul and eucalyptus.

Post harvest technology: The harvested spikes are dried in sun for 4-5 days until they are perfectly dry. The green to dry spike ratio is 10:1.5 by weight. The dried spikes have to be stored in moisture proof containers. Stem and roots are cleaned, cut into pieces of 2.5-5 cm length, dried in shade and marketed as piplamool. There are three grades of piplamool, based on the thickness. The commercial drug consists 0.5-2.5 cm long ,0.5-2.5 mm thick, cylindrical pieces dirty light brown in colour and peculiar odour with a pungent bitter taste, producing numbness to the tongue.

Properties and activity: The spike of long pepper contains 4-5% piperine, piplartin, piperolactam, N-isobutyl deca trans-2-trans-4-dienamide and piporadione alkaloides, besides 0.7 % essential oil. Roots gave the alkaloids piperine, piperlongumine (piplartine) and piperlonguminine; sesamine, methyl 3, 4, 5-trimethoxy cinnamate. Stem gave triacoutane 22, 23 - dihydrostigmasterol. Fruit essential oil contains piperidine, caryophyllene and sesquiterpene alcohol (Atal et al, 1975).

The root is plungent, hot, stomachic, laxative, anthelmintic and carminative. The fruit is sweetish, pungent, hot, stomachic, aphrodisiac, alterative, laxative, antidysenteric, emmenagogue, abortifacient, diuretic and tonic. The essential oil is antimicrobial and anthelmintic.

N-isobutyl-deca-trans-2-trans-4-dienamide is antitubercular.

Piperine is hypotensive, antipyretic, analeptic, and nerve stimulant (Warrier et al, 1995).... long pepper

Rivea Ornate

(Roxb.) Choisy.

Family: Convolvulaceae.

Habitat: South India.

Ayurvedic: Phanji (var.).

Siddha/Tamil: Machuttai.

Folk: Baravat, Phaang.

Action: Juice of the plant—used topically in haemorrhagic diseases and piles.... rivea ornate

Tenesmus

A symptom of disease affecting the lower part of the large INTESTINE, such as DYSENTERY, piles (HAEMORRHOIDS) or tumour. It consists of a constant sense of heavy discomfort about the lower bowel and desire to defaecate, coupled with straining when doing so, with the passage of mucus and often blood.... tenesmus

Terminalia

Terminalia spp.

Combretaceae

The genus Terminalia includes a large group of medicinally valuable trees. They belong to the family Combretaceae.

The most important medicinal species of the genus Terminalia are the following.

1) T. arjuna (Roxb.ex DC) Wight & Arn.

San: Arjunah, Kakubhah;

Hin: Arjun, Kahu, Kahua;

Mal: Marutu, Nirmarutu, Venmarutu, Attumarutu, Pulamatti;

Tam: Attumarutu, Nirmarutu, Vellaimarutu, Marutu;

Kan: Maddi.

It is a large evergreen tree commonly found in Madhya Pradesh, Bihar and Peninsular and India. It has buttressed trunk and spreading crown with drooping branches. Bark is smooth, grey outside and flesh coloured inside, flaking off in large flat pieces. Leaves are simple, sub-opposite, oblong or elliptic, coriaceous, crenulate, pale dull green above, pale brown beneath, often unequal sided, nerves 10-15 pairs and reticulate. Flowers are white, arranged in panicles of spikes with linear bracteoles. Fruits are ovoid or oblong with 5-7 short, hard angles or wings, the lines on the wings oblique and curving upward (Warrier et al 1996).

The bark is useful in fractures, ulcers, urethrorrhoea, leucorrhoea, diabetes, vitiated conditions of pitta, anaemia, cardiopathy, fatigue, asthma, bronchitis, tumours, internal and external haemorrhages, cirrhosis of the lever and hypertension. It is used in fractures and the powdered bark is taken with milk. The bark powder is diuretic and has a general tonic effect in cases of cirrhosis of liver. The bark has been considered by the ayurvedic physicians as well as by modern practitioners as a cardiac tonic. It is given as a decoction with milk (NRF, 1998). In Ayurveda, “Arjunaghrita” and “Arjunarishta” are two important cardiotonic preparations of this drug.

Fruits contain flavanones - arjunone and 5,7,2’, 4’ - tetramethoxy flavone and a chalcone - cerasidin. Other constituents are -sitosterol, friedelin, methyloleanolate, gallic acid, ellagic acid and arjunic acid. Bark gave a triterpene arjungenin, triterpene glucosides I, II and III. Stem bark gave flavones - baicalein and arjunolone characterised as 6,4’ - dihydraxy - 7-methoxy flavone. Stem bark yields oxalic acid and tannins besides complex glycosides (Bhatra et al, 1980). Bark is alexertic, styptic, antidysenteric, astringent, antiasthmatic, febrifuge, expectorant, cardiotonic aphrodisiac and diuretic. Fruit is deobstruent. Stem-bark is CVS and CNS active, diuretic and abortifacient. Aerial part is CNS depressant and semen coagulant.

2) T. alata Heyne ex Roth. Syn. T. tomentosa (Roxb. Ex. Dc.) W & A.

San: Dharaphala, Saradru, Sajada;

Hin. Ain;

Ben: Asan, Paishal;

Mal: Tehmbara;

Tam: Karramarda, Karu Murutha, Marudam, Pudavam.

This tree is distributed in Himalaya from Kangra eastwords to Goalpara in Assam and southwards throughout the Peninsular India, upto 1200 m. The bark of the tree is widely used in ulcers, fractures, bronchitis and diarrhoea. Hydrolysis of the gum gives oligosaccharides, disaccharides and monosaccharides. Leaves and fruits give -sitosterol. Bark is diuretic, antihaemorrhagic, styptic, cardiotonic and semen coagulant.

3) T. bellirica (Craertn.) Roxb.

San: Aksha, Anilaghanaka, Baheduka, Harya, Kalinda;

Hin: Bulla, Sagona;

Ben: Bahera, Baheri;

Tam: Akkam, Kalanduri, Tani;

Tel: Bhutavasamu Tadi, Tandra, Vibhutakamu.

Belliric Myrobalan is distributed throughout India, upto 900 m. Its bark is used in anaemia and leucoderma. The fruit is used in bronchitis, strangury, sore throat, diseases of eye, nose, heart and bladder, hoarseness and piles. It forms an important constituent of the ayurvedic drug ‘triphala’. Furits contain -sitosterol, gallic and ellagic acids, ethyl gallate, galloyl glucose, chebulagic acid and a cardiac glucoside bellaricanin. Alcoholic extract of the fruit possesses bile-stimulating activity. Alcoholic extract, 30 mg/kg does not affect blood pressure and respiration, but a higher dose of 60 mg/kg produces a fall in blood pressure. Furit has anticancerous and flower has spermicidal activity. Bark is mild diuretic. Fruit is astringent, antidropsical, antileprotic, antiinflammatory, antidiarrhoeal, antibilious, stomachic, antiasthmatic, tonic, anticephalgic, bechic, anthelmintic and attenuant. Kernel is narcotic. Semi -ripe fruit is purgative. Gum is demulcent (Husain et al, 1992)

4) T. bialata steud.

White Chugalam or silver grey wood is a common tree of Andaman Islands. Its bark is used as a cardiac stimulant.

5) T. Catappa Linn.

San: Grahadruma;

Hin: Badam;

Ben: Bangla Badam:

Tam: Natuvdom, Vadhamkottai;

Tel: Vedam, Voda Movettilla; Mar: Jangli Badama, Nat Badam.

Indian Almond or Tropical Almond is a popular tree cultivated throughout the warmer parts of India including Andaman Islands and other adjacent island. Oil from the kernel is a substitute for almond oil. The leaf is used in scabies and colic. Husk and endocarp contain tannins and pentosans. Oil from kernel contains oleic, linoleic, palmitic and stearic acids. Heart wood and stem bark contains -sitosterol and its palmitate. Heartwood in addition contains terminolic acid and triterpenic methyl esters. The aerial part of the plant is diuretic. The bark is astringent, mild diuretic, cardiotonic and antidysenteric. Leaf is sudorific, antirheumatic, antileprotic and anticephalalgic.

6) T. Coriacea (Roxb.) syn. T. tomentosa (Roxb. ex. DC.) W. & A. var. coriacea (Roxb.) C. B. Clarke

Tam: Anaimikkuvam, Sadagam;

Kan: Banapu;

Tel: Tani.

Leathery Murdah is a tree commonly used as a cardiac stimulant. It is widely distributed in the drier and warmer parts of Andhra Pradesh and Tamil Nadu upto 1350 m and in Central India. Its bark is mainly used as a cardiac stimulant and in atonic diarrhoea and callous ulcer. It is also CVS active.

7) T. myriocarpa Heurck. & Muell. Arg.

Ben: Panisaj; Ass: Hollock, Jhalna.

Hollock is a tree of the Himalayas widely distributed from Nepal to Arunachal Pradesh and in Assam at 1000 m. The bark is cardiac stimulant and mild diuretic. Bark give -sitosterol, fructose and 4,4’,5,5’,6,6’ - hexadydroxy diphenic acid dilactone. Bark also contains tannis - ellagic, gallic, chebulinic and chebulagic acids.

8) T. Pallida Brandis.

Tam: Vellai Kadukkay;

Tel: Tella Karaka, Velama Karka.

The plant is distributed throughout south India, upto 600m. Its bark is a mild diuretic.

9) T. Paniculata Roth.

Mal: Marutu, Pe Marutu, Ven Marutu;

Tam: Pei Kadukai, Ven Maruthu, Ilai Kadukkay, Marudu, Pullatti;

Tel: Nimiri, Pulamaddi, Putamanu, Pulanallamanu;

Kan: Maruva, Matti.

Flowering Murdah is a tree which is widely used in opium poisoning. It is distributed in the Western and Eastern Ghats, upto 1200m. The bark is used in parotitis and flowers in opium poisioning. Heart wood give 3, 3’-0-di-methylellagic acid and 3,4,3’0-trimethyl flavellagic acid, -sitosterol, an uncharacterized triterpene carboxylic acid; a glycoside -3,3’ di-0 - methyl ellagic acid - 4 - monoglucoside and 0 - penta methyl flavellogic acid. The stem bark is anticancerous, diuretic, cardiotonic CVS active and shows antagonism of amphetamine hyperactivity. Flower is anticholerin (Husain et al, 1992)

10) Terminalia chebula Retz. Syn. Myrobalanus chebula (Retz.) Gaertner

Eng: Chebulic myrobalan;

San,

Ben: Haritaki;

Hindi:Harara, Harir,

Har; Mal:Kadukka; Ass:Hilikha; Kan:Alale;

Mar:Habra,

Hirada;

Ori:Harida;

Guj: Hirdo;

Pun:Helela;

Tam:Amagola;

Tel: Karaka

Chebulic myrobalan is a medium deciduous tree, the fruit of which is a common constituent of “Triphala” capable of imparting youthful vitality and receptivity of mind and sense. It is a major constituent in the ayurvedic preparations like Abhayarishta, Abhaya modak, Haritaki khand, Triphaladi churnam and Agastya rasayanam. In allopathy it is used in astringent ointments. In unani system, it is used as a blood purifier. The pulp of the fruit is given in piles, chronic diarrhoea, dysentery, costiveness, flatulence, asthma, urinary disorders, vomiting, hiccup, intestinal worms, ascites and enlarged spleen and liver. Powder of the fruit is used in chronic ulcers and wounds, carious teeth and bleeding ulceration of the gums. The bark is a good cardiac tonic. The fruit is valuable for its tannins and dyes. The wood is used for building purposes, agricultural implements, plywood and match box industries. It is also grown as a shade tree.

The plant is found throughout India chiefly in deciduous forests, on dry slopes upto 900m especially in Bengal, Tamil Nadu, West coast and Western Ghats. The plant is also reported in Sri Lanka, Nepal and Burma.

Terminalia chebula Retz. syn. Myrobalanus chebula (Retz.) Gaertner comes under family Combretaceae. It is a medium sized deciduous tree with a cylindrical bole, rounded crown, spreading branches with dark brown bark and brownish gray heartwood. Leaves are simple, alternate or subopposite, ovate or elliptic ovate with short petioles bearing 2 glands below the blades. Flowers pale yellow or white in 4-10cm long axillary spikes. Calyx tube hairy pale yellow and 5 lobed; no petals. Stamens consist of 10 filaments subulate, anthers small; ovary inferior, 1-celled with 2-3 pendulous ovule. Fruit is a drupe, ovoid glossy, glabrous, faintly angled and yellow to orange brown in colour. Seeds are hard and pale yellow.

Kernel oil of Chebulic myrobalan contains 6 fatty acids viz. Palmitic, stearic, oleic, linoleic, arachidic and behenic acid. The fruits contain chebulinic acid, tannic acid, gallic acid, chebulin and tannin. Leaves contain terpenes and saponins and -sitosterol is present in the bark (Beri, 1970; Khalique and Nizamuddin, 1972; Miglani and Chawla, 1974). Fruits are astringent, purgative, tonic, carminative, alternative and antispasmodic. Flowers and fruits are antiviral and hypoglycaemic. Wood is oxytocic and hypothermic (Husain et al, 1992).

Agrotechnology: Terminalia species are, in general, subtropical trees. Young plants prefer shade while the matured plants tolerate light frost and drought. It grows well in hilly areas. This is propagated by seeds. Natural multiplication happens rarely due to the poor seeds germination. Seeds soaked in water for 48 hours before sowing in seedbeds which should be covered with straw after sowing. It is watered immediately. Usually it takes 3-5 months to germinate. It can be transferred to polybags at two-leaf stage. One-year-old seedlings are ready for transplanting. For transplanting, pits are made of 50cm cube at a spacing of 4m. Organic manure, added regularly, promotes growth. Irrigation is required during first year. Weeds should be removed regularly. This plant grows slowly. It fruits within 6-7 years. This is continued for many years. It is coppiced well. Fruits are collected immediately after falling down or covered with soil to protect it from pests. Fruits dried well in sun and used or stored. The hard seed coat is removed before sowing.... terminalia

Witch-hazel

A preparation of the bark, twigs, and dried leaves from Hamamelis virginiana, a plant found in the United States. It has strong astringent properties and is used to check haemorrhages and excessive mucous discharges, and also for piles (see HAEMORRHOIDS).... witch-hazel

Amorphophallus Campanulatus

(Roxb.) Blume ex Decne.

Family: Araceae.

Habitat: Native to tropical Asia; cultivated throughout India.

English: Elephant-foot Yam.

Ayurvedic: Suurana, Kanduula, Arshoghna, Kand-ayak, Kandala.

Unani: Zamin-qand, Zamikand.

Siddha/Tamil: Chenaikkizhangu. Kaathukarunai (wild var.)

Action: Corm is prescribed in bronchitis, asthma, abdominal pain, emesis, dysentery, enlargement of spleen, piles, elephantiasis, diseases due to vitiated blood, rheumatic swellings.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of corm in prostatic hyperplasia.

(The corm is irritant due to the presence of calcium oxalate. It can be con- sumedafterit iswashedwell andboiled in tamarind water or butter milk.)

The corm contains an active di- astatic enzyme amylase, betulinic acid, tricontane, lupeol, stigmasterol, beta- sitosterol and its palmitate and glucose, galactose, rhamnose and xylose.

Intake of 3.6-7.2 g of konjac (Amor- phophallus konjac tuber) mannan for 90 days reduced the dose of insulin or hypoglycaemic drugs (in human clinical study). (Francis Brinker.)

Amorphophallus sylvatius Kunth. is equated with the wild var. of Suu- rana, used especially in the treatment of piles.

Dosage: Dried corm—2-10 g powder. (API Vol. III.) 3-5 g powder. (CCRAS.)... amorphophallus campanulatus

Anogeissus Latifolia

Wall. ex Bedd.

Family: Combretaceae.

Habitat: Central and southern India.

English: Axle-wood, Button tree, Ghatti tree.

Ayurvedic: Dhava, Dhurand- hara, Shakataahya. Indravrksha (A. acuminata Wall. ex Bedd. is a related sp. of Dhava).

Unani: Dhaawaa.

Siddha/Tamil: Vellaynaga.

Folk: Ghatti (Gum).

Action: Astringent, cooling, used in diarrhoea, dysentery, ulcers, piles, urinary disorders and dysuria. Gum—used as a tonic after delivery.

The leaves, bark and heartwood yield quinic and shikmik acids; leaves contain gallotannin (90-95% of the tannins). The young leaves and shoots contain 50% tannins (dry basis). The bark contains 12-18% tannins. Heart- wood contains gallic acid, ellagic acid, its derivatives, quercetin and myricetin.

The gum is mainly the calcium salt of a complex, high molecular weight polysaccharic acid (ghattic acid). The gum is a substitute for Gum arabic.... anogeissus latifolia

Asclepias Curassavica

Linn.

Family: Aristolochiaceae.

Habitat: Indigenous to the northern parts of southern Europe, Central and East-Central Europe; cultivated in the United States. A related sp., Asarum himalaicum, synonym A. canadense, is reported from the eastern Himalayas.

English: Asarbacca, Hazelwort, Wild Nard.

Unani: Asaaroon, Subul-e-Barri, Naardeen-Barri.

Folk: Tagar Ganthodaa.

Action: Brain and nervine tonic, diuretic, deobstructant and anti- inflammatory; used in bronchial spasm and in preparations of cephalic snuffs.

The volatile oil (0.7-4%) consists of asarone up to 50%, asaraldehyde 2-3%, methyleugenol 15-20%, with bornyl acetate, terpenes and sesquiterpenes. Asarone and its beta-isomer is found to be carcinogenic in animals. The rhizome, in addition, contains caffeic acid derivatives and flavonoids.

A related sp., Asarum canadense L., indigenous to North America and China, contains a volatile oil (3.5-

Family: Asclepiadaceae.

Habitat: Naturalized in many parts of India as an ornamental.

English: Curassavian Swallow- Wort, West Indian Ipecacuanha, Blood-Flower.

Ayurvedic: Kaakanaasikaa (substitute).

Folk: Kaakatundi (Kashmir).

Action: Spasmogenic, cardiotonic, cytotoxic, antihaemorrhagic, styptic, antibacterial. Various plant parts, as also plant latex, are used against warts and cancer. Root—used as an astringent in piles. Leaves—juice, antidysenteric, also used against haemorrhages. Flowers—juice, styptic. Alcoholic extract of the plant—cardiotonic.

An alcoholic extract of the Indian plant has been reported to contain a number of cardenolides, including calactin, calotropin, calotropagenin, coroglaucigenin, uzarigenin, asclepin, its glucosides and uzarin. Asclepin, the chief active principle, is spasmogenic and a cardiac tonic, having longer duration of action than digoxin (96 h in cat, as opposed to the 72 h of digoxin). Calotropin exhibits cytotoxic activity.

Pleurisy root of the U.S. is equated with Asclepias tuberosa. It is used for cold, flu and bronchitis in Western herbal medicine.

Toxic principles of the herb include galitoxin and similar resins, and glu- cofrugoside (cardenolide). Toxicity is reduced by drying.... asclepias curassavica

Burnet, Greater

Garden Burnet. Salad Burnet. Sanguisorba officinalis L. Herb.

Action: astringent tonic, anti-haemorrhagic. Mild antibacterial.

Uses: Irritable bowel, ulcerative colitis, excessive menstruation, gargle for throat infections.

Traditional: tea used as a wash for piles and anal irritation, or as a poultice for sores and wounds. Widely used in Chinese medicine.

Preparations: Thrice daily.

Tea: 2 teaspoons to each cup boiling water; infuse 5 minutes. Half-1 cup. Liquid extract: half-1 teaspoon in water.

Tincture BHP (1983) 1:5 in 45 per cent alcohol. Dose 2-8ml. ... burnet, greater

Butcher’s Broom

Ruscus aculeatus, L. Rhizome.

Action: diuretic, diaphoretic, laxative, deobstruent, anti-inflammatory, veinous tonic. Action similar to Wild Yam: used in synthesis of steroid hormones. Antispasmodic. Haemostatic.

Uses: Varicose veins, piles, jaundice, obstructed menstruation, sluggish circulation, oedema. To arrest haemorrhage.

Decoction: half an ounce fine-cut herb to 1 pint water simmered gently 20 minutes. Dose: half-1 cup thrice daily.

Powder, capsules: 270mg. 3 capsules twice daily during meals. (Arkocaps)

Endopharm capsules for piles. ... butcher’s broom

Averrhoa Carambola

Linn.

Family: Oxalidaceae; Averrhoaceae.

Habitat: Native to Malaysia; cultivated throughout the warmer parts of India, especially in Kerala.

English: Carambola, Star Fruit, Chinese Gooseberry.

Ayurvedic: Karmaranga.

Unani: Khamraq, Karmal.

Siddha/Tamil: Tamarattai.

Folk: Kamarakh.

Action: Root—antidote in poisoning. Leaf and shoot—applied externally in ringworm, scabies, chickenpox. Flower—vermicidal. Fruit—laxative, antidysenteric, antiphlogistic, febrifuge, anti- inflammatory, antispasmodic (used in hepatic colic, bleeding piles). Seeds—galactogenic; in large doses act as an emmenagogue and cause abortion.

The fruits are a fairly good source of iron but deficient in calcium. They also contain oxalic acid and potassium oxalate. The presence of fluorine is also reported. A wide variation of vitamin-C content (0.3-23.0 mg/100 g) is recorded from different places in India. Sugar (3.19%) consists mainly of glucose (1.63%).... averrhoa carambola

Bassia Longifolia

Koen.

Synonym: Madhuca longifolia (Linn.) Macbride.

Family: Sapotaceae.

Habitat: South India; common in the monsoon forests of Western Ghats.

English: Mowra Butter tree, South Indian Mahua.

Siddha/Tamil: Illupei, Elupa, Naatu, Iluppei, Iruppei.

Action: Flowers—laxative, bechic (used in coughs, colds and bronchitis), stimulant and nervine tonic. Seed oil—galactogenic, anticephalalgic, laxative in cases of habitual constipation and piles; used externally in rheumatism and skin affections. Bark, seed oil and gum—antirheumatic.

The herb contains 17% tannins and is used for bleeding and spongy gums, tonsillitis, ulcers, rheumatism and diabetes mellitus. Roots are applied to ulcers.

Seed kernel gave protobassic acid (a sapogenol) and two major saponins— Mi-saponins A and B. Mi-saponins (bisdesmosides of protobassic acid) exhibit anti-inflammatory activity in rheumatism.

The carollas are a rich source of sugars and contain an appreciable amount of vitamins and calcium (total sugars 72.9%, calcium 140 mg/100 g). Sugars are identified as sucrose, maltose, glucose, fructose, arabinose and rham- nose. Flowers are largely used in the preparation of distilled liquors. They constitute the most important raw material for fermentative production of alcohol.... bassia longifolia

Bauhinia Racemosa

Lamk

Family: Caesalpiniaceae.

Habitat: Sub-Himalayan tracts from Ravi eastwards, ascending to 1,000 m. in the Uttar Pradesh, West Bengal and Central and South India.

Ayurvedic: Ashmantaka, Kanchini.

Unani: Kachnaar.

Folk: Aapataa (Maharashtra), Kachnaala.

Action: Bark—highly astringent, anti-inflammatory (used in glandular inflammations, skin diseases, ulcers), cholagogue. Leaves—anthelmintic; with onion for diarrhoea. Flowers—used in haemorrhages, piles; also in cough. Seed—antibacterial.

Octacosane, beta-amyrin and beta- sitosterol have been isolated from the bark. EtOH (50%) extract of seeds exhibited anticancer activity.... bauhinia racemosa

Bauhinia Variegata

Linn.

Synonym: B. candida Roxb.

Family: Caesalpiniaceae.

Habitat: Punjab, Western Peninsula and Assam. Also cultivated in gardens.

English: Mountain Ebony, Buddhist Bauhinia.

Ayurvedic: Kaanchanaara, Kaan- chanaaraka, Kanchanak, Kaan- chana, Gandhaari, Sonapushpaka, Ashmantaka.

Siddha/Tamil: Sivappumanchori.

Action: Buds—a decoction is given in piles (also used against tumours), haematuria, menorrhagia. Dried buds are used in diarrhoea, dysentery, worm infestation, piles and tumours. Root— carminative, used in dyspepsia and flatulence (a decoction is reported to prevent obesity). Bark—astringent, anthelmintic; used externally in scrofula and skin diseases. Seeds—possess human blood agglutinating activity. Leaf— antifungal.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicated the use of the stem bark in lymphadenitis and goitre. (Ka- anchnaar Guggulu is prescribed for glandular swellings and goitre.)

Water-soluble portion of alcoholic extract of the plant showed preventive effect against goitre in rats.

Flowers gave flavonoids, kaempfe- rol-3-galactoside and kaempferol-3- rhamnoglucoside. The stem bark yields hentriacontane, octacosanol and stigmasterol. Stem contains beta-sitos- terol, lupeol and a flavanone glyco- side.

Dosage: Stem bark—20-30 g for decoction. (API Vol. I.)... bauhinia variegata

Hemlock

Conium maculatum L. French: Cigue?. German: Schierling. Spanish: Cicuta. Italian: Cleuta. Indian: Kirda?man. Iranian: Bikhi-i-Tafti. Arabian: Banj-e-rumi. Parts used: leaves, fruit. Constituents: alkaloids, volatile oil.

Poisonous, taken internally but has been used with success as a poultice or ointment topically for malignant glands. Continued use has had a shrinking effect reducing the gland from stony hardness. Schedule 1. Poultice for use by a medical practitioner only. Other external uses: itching anus, piles.

Pharmacy only medicine ... hemlock

Krameria Root

Rhatany root. Krameria triandra. Dried root.

Action: anti-tubercle, haemostatic, powerful astringent, anti-microbial.

Uses: Basis of treatment for tuberculosis with Umckaloabo in the 1920s. See: UMCKALOABO. Spongy bleeding gums, bleeding piles, nasal polyps (powder used as snuff), haemoptysis, incontinence of urine. Preparations. Average dose, half-2g. Thrice daily.

Decoction. Half-l teaspoon to each large cup water gently simmered 20 minutes. Dose: one-third to half a cup.

Tincture Krameria BPC (1949). Dose 30-60 drops (2-4ml).

Liquid extract BPC 1923. Dose: 2-4ml. ... krameria root

Bauhinia

Bauhinia variegata

Caesalpiniaceae

San: Kancanarah, Kovidarah;

Hin: Kancanar;

Ben: Rakta Kanchan;

Tam: Sigappu-mandarai

Mal: Mandaram, Chuvannamandaram, Malayakatti, Kongu, Kongumandaram;

Tel: Daeva Kanchanamu, Mandara;

Kan: Ullipe, Kanchavala, Kempu Mandara

Importance: In traditional medicine, Bauhinia is extensively used in glandular diseases and as an antidote to poison. The drug is also reported to be useful in dysentery, diarrhoea, piles and worms (Kurup et al, 1979; Sharma et al, 1983). They are useful in vitiated conditions of kapha and pitta, diarrhoea, dysentery, skin diseases, leprosy, intestinal worms, tumours, wounds, ulcers, inflammations, scrofula, protoptosis, haemorrhoids, haemoptysis, cough, menorrhagia and diabetics. Usirasavam and Candanasavam are some of the preparations using the drug. An important Ayurvedic preparation, “Kanchnar Guggal” contains bark of this plant. In Unani system, the flowers are used in “Hab Mussafi Khun”, for skin diseases, the bark is used in “Sufuf Kalan”-an aphrodisiac.

Distribution: The plant is distributed in the Sub-Himalayan tracts from the Indus eastwards and throughout the dry forests of India, ascending to 1300m. It is also cultivated throughout the plains.

Botany: Bauhinia variegata Linn. syn. B.

candida Roxb. belonging to the family Caesalpiniaceae is a moderate sized deciduous tree with vertically cracked grey bark, wood moderately hard, greyish brown with irregular darker patches. Leaves are of 2 leaflets, connate for about two-thirds up. Leaflets are ovate with rounded apex, 10-15cm long, pubescent beneath when young and coriaceous. Flowers are white or pink, the uppermost petal darker and variegated usually appearing before the leaves in short axillary or terminal racemes. Stamens are 5 and stamenodes absent. Fruits are flat dehiscent pods with 10-15 seeds (Warrier et al, 1993).

Other important species of the genus Bauhinia are as follows.

1. B. tomentosa Linn.

It is the yellow or golden flowered one, commonly known as Manja Mandaram. It is found in Africa and Asia. In India it is found wild in dry deciduous forests and often cultivated. The plant is antidysenteric, antidote for snakebite and scorpion sting and also used in liver complaints. The bark is astringent. Root bark is vermifuge. Fruit is diuretic. Seed is tonic, wound healing and aphrodisiac.

2. B. purpurea Linn.

Pink Bauhinia or Camel’s Foot tree is found in South and S. E. Asia. In India, it is found in deciduous forests. Root is carminative and tonic. Bark is astringent and antidiarrhoeal and is used in ulcer and goitre. Flowers are laxative. The experimental studies conducted by Sijoria and Prasad (1979) on animals indicate that B. purpurea is very effective in normalising the thyroid gland.

3. B. racemosa Lam.

The plant is found in Sub-Himalayan tracts, in U.P, West Bengal, Central and South India. The leaf is anticephalalgic and antimalarial. Bark is astringent, antidiarrhoeal. The seeds are antibacterial. Stem-bark is CVS and CNS active, hypothermic and anticancerous.

4. B. malabarica Roxb.

Malabar Mountain Ebony is found in Sub-Himalayan tracts, from Kumaon to West Bengal, ascending to 1350m, Assam, Bihar and South India. The flowers of this plant are antidysenteric.

5. B. retusa Roxb.

The plant is distributed in north-western Himalayas from the Beas eastwards, Himachal Pradesh, U.P., Orissa, M.P. and A.P. The gum of the plant is emmenagogue, diuretic and can be used externally in sores. The seed is hypoglycaemic and hypocholesterolaemic. The aerial part is CVS active and has effect on respiration.

6. B. vahlii W.&A.

Camel’s Foot climber is found in Punjab, Bihar, Assam, Madhy Pradesh, Andra Pradesh and Tamil Nadu. Leaf is demulcent. Seed is tonic and aphrodisiac. Stem is CVS active, antiarrhythmic and spasmolytic.

Agrotechnology: Well drained hilly areas are ideal for the cultivation of Bauhinia. The plant is seed propagated. Seeds are formed in February-March. Seeds are to be collected from the dried pods, soaked in water for 12 hours before sowing in seedbeds. At four-leaved stage they are to be transferred to polybags. Two month old seedlings from polybags are used for field planting. Pits of size 60cm cube are to be taken and filled with 10kg dried cowdung mixed with topsoil and formed into a mound. On these seedlings are to be planted at a distance of 6-7.5m. Irrigation is to be given in the first year. Two weedings and application of organic manure once is required in a year. The plant is not attacked by any serious pests and diseases. The plant flowers on the third year. At the end of tenth year the tree can be cut and wood used for medicinal purposes (Prasad et al, 1997).

Properties and activity: Flowers contain flavanoids-kaempferol-3-galactoside and kaempferol-3- rhamnoglucoside. Stem bark yields hentriacontane, octacosanol and stigmasterol. Stem yields -sitisterol, lupiol and a flavanone glycoside-5, 7-dimethoxy flavanone 4-O- -L- rhamnopyranoside- -D-glucopyranoside. Seeds possess human blood agglutinating activity. Stem bark is hypothermic, CNS active and depressant. Bud, flower, leaf and stembark are antibacterial. Stem possesses juvenoid activity. Bark is alterative, tonic, antileprotic and antirheumatic. Bud is antidysenteric. Root is carminative and antidote for snakebite. Bark, flower and root promote suppuration. Bark and bud are astringent and vermifuge (Husain et al, 1992).... bauhinia

Boswellia Serrata

Roxb.

Family: Burseraceae.

Habitat: The drier parts of Peninsular India.

English: Indian Frankincense, Indian Olibanum.

Ayurvedic: Shallaki, Susravaa, Gajabhakshyaa, Salai. Gum— Kunduru.

Unani: Kundur (gum).

Siddha/Tamil: Parangisambirani, Kungli.

Folk: Salai Guggul.

Action: Gum-resin—antiseptic, anti-inflammatory, antiatheroscle- rotic, emmenagogue, analgesic, sedative, hypotensive. Also used in obesity, diarrhoea, dysentery, piles, urinary disorders, scrofulous affections. Oil—used topically in chronic ulcers, ringworm.

Nonphenolic fraction of gum-resin exhibited marked sedative and analgesic effect in rats. It produced a marked and long-lasting hypotension in anaesthetized dogs.

Many derivatives of 3-keto-methyl- beta-boswellic ester, isolated from the gum-resin., have been prepared; a py- razoline derivative exhibited maximum anti-inflammatory activity. (Gum-resin is used in osteoarthri- tis, juvenile rheumatoid arthritis, soft tissue fibrositis and spondylitis, also for cough, bronchitis, asthma, mouth sores.)

Essential oil from gum-resin—anti- fungal.

Gum-resin contains triterpenes of oleanane, ursane and euphane series. Stem and fruit—hypoglycaemic.

Dosage: Gum-resin—1-3 g (API Vol. IV.)... boswellia serrata

Brunella Vulgaris

Linn.

Synonym: Prunella vulgaris Linn.

Family: Labiatae; Lamiaceae.

Habitat: The Himalayas from Kashmir to Bhutan at altitudes of 1,400-4,000 m, in Khasi Hills and hills of South India.

English: Self-heal.

Unani: Substitute for Ustukhudduus. (Lavandula stoechas Linn.)

Folk: Dhaaru.

Action: Wound healing, expectorant, antiseptic, astringent, haemostatic, antispasmodic. Leaf- used in piles; and as a cooling herb for fevers.

The herb contains vitamins A, B, C and K; flavonoids; rutin. Flower spikes are liver-restorative, hypotensive, an- tioxidant.

Lupeol, stigmasterol and beta-sitos- terol are obtained from the unsapo- nifiable fraction from the leaves, the saponifiable fraction gave lauric,... brunella vulgaris

Butea Monosperma

(Lam.) Taub.

Synonym: B. frondosa Koenig ex Roxb.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout India, up to 1,200 m except in very arid regions.

English: Flame of the Forest, Butea Gum, Bengal Kino.

Ayurvedic: Paalasha, Kimshuka, Raktapushpaka, Kshaarshreshtha, Brahmavriksha, Samidvar.

Unani: Dhaak, Samagh Dhaak, Kamarkas.

Siddha/Tamil: Palasam, Purasus.

Folk: Tesu.

Action: Bark—astringent, styptic (prescribed in bleeding piles, ulcers, haemorrhages, menstrual disorders), anthelmintic. Flowers— astringent, diuretic, emmenagogue (also given for leucorrhoea). A decoction of flowers is given in diarrhoea and haematuria, also to puerperal women. Seeds—clinical use of seeds as an anthelmintic drug is not considered safe in humans.

Leaves—antibacterial. Stem bark— antifungal.

An aqueous extract of flowers has shown hepatoprotective activity against CCl4-induced liver injury in albino rats.

Extracts of flowers have exhibited significant anti-oestrogenic activity in mice. The seed suspension, on oral administration to albino rats (175 and 350 mg/kg body weight), showed 38.46 and 68.75% cases, respectively, where pregnancy was not interrupted but foetus was malformed.

Alcoholic extract of the whole plant produced persistent vasodepression in cats.

The plant contains flavonoids and glucosides—butin, butrin, isobutrin and palastrin. Flowers contain butrin, coreopsin, monospermoside and their derivatives and sulphurein; also chal- cones.

Dosage: Stem bark—5-10 g powder (API Vol. II); flower—3-6 g powder; seed—3 g powder; gum—0.5-1.5 g (API Vol. IV.)... butea monosperma

Butea Superba

Roxb.

Family: Papilionaceae; Fabaceae.

Habitat: Central and Southern India.

Ayurvedic: Lataa-Palaash (orange or orange scarlet-flowered var.).

Action: Seeds—sedative and anthelmintic; decoction emollient and used topically for piles. Seed oil—anthelmintic and hypotensive. Seeds exhibit haemagglutinating activity against human ABO red cells. Roots—hypotensive. Watery sap from stems is used for drinking purposes. Bark is used in tonics and elixirs.

White-flowered var. is equated with Butea parviflora Roxb.... butea superba

Caesalpinia Coriaria

(Jacq.) Willd.

Family: Caesalpiniaceae.

Habitat: Grows abundantly in South India, also cultivated in North-western India and West Bengal.

English: American Sumac, Divi-divi Plant.

Siddha/Tamil: Kodivelam.

Folk: Libi-dibi; Divi-divi.

Action: Bark—febrifuge, antiperi- odic. Pod—astringent (in piles). Fruit—semen coagulant.

All parts of the plant contain tannin, the maximum amount occurring in the pods (69.4%). The tannins from pods comprise pyrogallol type of hy- drolysable tannins and consists of gal- lotannin and ellagitannin. Divi-divi closely resembles myrobalans both in nature and contents of tannins. Seeds contain little or no tannin.

The plant is used for treating freckles. Leaves contain ellagic and gallic acids, catechol and tannins.

Ethanolic extract of the leaves showed antifungal activity.... caesalpinia coriaria

Calamus Rotang

Linn.

Synonym: C. roxburghii Griff.

Family: Palmae; Arecaceae.

Habitat: Central and South India.

English: Rotang, Rattan, Chair Bottom Cane.

Ayurvedic: Vetra, Abhrapushpa.

Siddha/Tamil: Pirambu.

Action: Astringent, antidiarrhoeal, anti-inflammatory (used in chronic fevers, piles, abdominal tumours, strangury), antibilious, spasmolytic. Wood—vermifuge.

The plant is used in convulsions and cramps. The presence of a saponin in the stem, an alkaloid in the leaves and a flavonoid in the root is reported.... calamus rotang

Capparis Zeylanica

Linn.

Synonym: C. horrida Linn.f.

Family: Cappariadaceae.

Habitat: Common in plains as a hedge plant.

English: Ceylon Caper.

Ayurvedic: Ahimsra (Himsraa and Ahimsra are synonyms). Vyaaghranakhi.

Siddha/Tamil: Aathondai.

Folk: Kareruaa.

Action: Root bark—sedative, stomachic, anticholerin, diuretic febrifuge. Leaves—applied as poultice to piles, swellings, boils.

The plant contains a saponin and p- hydroxybenzoic, syringic, vanillic, fer- ulic and p-coumaric acids. The leaves contain beta-carotene. The leaves and seeds contain glucocapparin, alpha- amyrin, n-triacontane and a fixed oil.

Aerial parts exhibited spasmolytic activity.... capparis zeylanica

Carica Papaya

Linn.

Family: Caricaceae.

Habitat: Native to West Indies and Central America; now cultivated in Uttar Pradesh, Punjab, Rajasthan, Gujarat, Maharashtra and South India.

English: Papaya, Papaw.

Ayurvedic: Erand-karkati, Papitaa.

Unani: Papitaa Desi.

Siddha/Tamil: Pappaali, Pappayi.

Action: Ripe fruit—stomachic, digestive, carminative, diuretic, galactagogue. Useful in bleeding piles, haemoptysis, dysentery and chronic diarrhoea. Seeds— emmengagogue, abortifacient, vermifuge. Juice of seeds is administered in enlarged liver and spleen, and in bleeding piles.

Key application: Papain, the enzyme mixture extracted from raw papain (latex of Carica papaya), has been included among unapproved herbs by German Commission E. Experiment-based as well as clinical research indicate that papain may be effective (in the treatment of inflammations) in high doses (daily dose 1500 mg corresponding to 2520 FIP units).

Unripe fruit—emmengagogue and abortifacient. Latex—applied topically on eczema, ringworm, psoriasis, corns, warts, sloughing wounds, carbuncles and eschar of burns.

Green parts of the plant and seed contain an alkaloid carpaine. Seeds also contain carpasemine.

Latex contain enzymes—papain and chymopapain and alkaloids carpaine and pseudocarpaine. A proteinaceous material from latex showed anticoagulant activity; in higher doses it is heart depressant and as a spasmogen on smooth muscle of guinea pig ileum. An alkaloid solution showed depressant action on heart, blood pressure and intestine.

The anthelmintic action of seeds against Ascaris lumbricoides is due to carpasemine.

Papain, an enzyme mixture prepared from the fruit, seeds and leaf, hydrolyses polypeptides, amides and esters, particularly when used in an alkaline environment, and is used in digestive disorders.

Papain inhibits platelet aggregation, which may further increase the risk of bleeding in patients also taking anticoagulants. Concurrent administration of cyclophosphamide with papain caused sever damage to lung tissues in rats. (Sharon M. Herr.)

Chymopapin C is an immunosup- pressive enzyme from plant extract. Carpaine, extracted from the plant, exhibited anti-tubercular activity, also antitumour in vitro, and hypotensive.

Dosage: Leaf—40-80 ml infusion; latex—3-6 g (CCRAS.)... carica papaya

Cassia Sophera

Linn.

Family: Calsalpiniaceae.

Habitat: In gardens as hedge throughout India.

English: Sophera Senna.

Ayurvedic: Kaasamarda.

Unani: Kasondi.

Siddha/Tamil: Ponnaavaarai.

Action: Leaves, seeds, bark— cathartic; considered specific for ringworm and other skin diseases (bark may cause dermatitis); used for bronchitis and asthma.

A paste of leaves is used for treating piles. An infusion of fresh leaves, with sugar, is given in jaundice. Plant is spasmolytic. Alcoholic extract of leaves is intestinal and bronchial muscle relaxant.

The leaves contain a flavone glyco- side and sennoside. Root bark contains anthraquinones, chrysophanol, physcion and beta-sitosterol. Heart- wood gave isomeric derivatives, 1,2, 7-trihydroxy-3-methylanthraquinone, along with sopheranin, beta-sitosterol, chrysophanol, physcion, emodin, 1- octadecanol and quercetin.... cassia sophera

Cissampelos Pareira

Linn.

Family: Menispermaceae.

Habitat: The tropical and subtropical parts of India.

English: Velvet-Leaf Pareira, Pareira Brava.

Ayurvedic: Paathaa, Ambashthaa, Varatiktaaa, Vriki, Aviddhakarni, Piluphalaa, Shreyashi.Bigger var., Raaja Paathaa, is equated with Stephania hernandifolia Walp.)

Unani: Paathaa.

Siddha/Tamil: Paadakkizhangu, Appatta.

Action: Root astringent, an- tispasmodic (used for cramps, painful menstruation), analgesic, antipyretic, diuretic, antilithic and emmenagogue. Prescribed for diarrhoea, dysentery, piles, urogenital affections (cystitis, nephritis, menorrhagia) Root paste is applied topically on scabies and eruptions on the body. Also used for preventing miscarriage.

The Ayurvedic Pharmacopoeia ofIn- dia attributed blood purifying properties to the root and indicated it in lactal disorders.

Hayatine (dl-beberine) is the principal alkaloid of the root. Its derivatives, methiodide and methochloride are reported to be potent neuromus- cular-blocking agents.

Not to be confused with Abuta grandiflora, a South American medicinal plant.

Dosage: Root—3-6 g powder. (API Vol. I.) the plant hastens fracture-healing by reducing the total convalescent period by 33% in experimental rats and dogs; it aids in recovery of the strength of the bones up to 90% in 6 weeks.

Dosage: Stem—10-20 ml juice. (API Vol. III.)... cissampelos pareira

Citrullus Colocynthis

Schrad.

Family: Cucurbitaceae.

Habitat: Throughout India.

English: Colocynth Bitter Apple.

Ayurvedic: Indravaaruni, Indraval- li, Indravaarunikaa, Gavaakshi, Chitraa, Chitraphalaa, Indraasuri, Mrigaani, Mrigairvaaru, Vishaalaa, Vishaalyka, Indraayana. Ain- dri (also equated with Bacopa monnieri).

Unani: Hanzal.

Siddha/Tamil: Kumatti.

Action: Dried pulp of ripe fruit— cathartic, drastic purgative, irritant and toxic. The pulp is used for varicose veins and piles. A paste of root is applied to various inflammations and swellings. The cataplasm of leaves is applied in migraine and neuralgia.

The Ayurvedic Pharmacopoeia of India indicated the use of the fruit in jaundice; the root in diseases of the liver and spleen and the leaf in cutaneous affections and alopecia.

Colocynth contains up to 3% cucur- bitacin. The drug and its preparations cause drastic irritation of the gastrointestinal mucosa and haemorrhages.

Cucurbitacins include cucurbitacin E-, J-, L-glucosides. In addition, the pulp contains caffeic acid derivatives (chlorogenic acid).

Roots contain aliphatic compounds. Ethanolic extract (50%) shows significant anti-inflammatory activity in albino rats.

Leaves and flowers contain querce- tin and kaempferol. The ethanolic extract of leaves and flowers exhibits antibacterial activity against a number of Gram-positive and Gram-negative bacteria.

The powder is toxic at 0.6-1.0 g. The fruit exhibited carcinogenic activity in animal studies.

Dosage: Dried fruit—125-500 mg powder. (API Vol. III.) Root—1- 3 g. powder. (CCRAS.) Dried leaf— for external use. (API Vol. II.)... citrullus colocynthis

Common Indigo

Indigofera tinctoria

Papilionaceae

San:Nilini, Ranjani, Nilika, Neelam, Aklika, Asita, Bhadra; Ben, Guj:Nil;

Hin:Gouli;

Mal: Neelamari;

Tam: Averi;

Tel: Aviri, Nili;

Kan: Nili; Mar: Nali; Ori: Neli

Importance: Common indigo or Indian indigo is a branching shrub which grows upto 2m high. Nili is a reputed drug produced from this plant which is used in ayurveda for the promotion of hair growth and it forms a major ingredient of preparations like nilibhringadi oil. This is the original source of natural indigo. Due to antitoxic property it is also a good remedy for poisons. According to Bhavaprakasa, nili is purgative in action, bitter, hot, cures giddiness, abdominal enlargement, vatarakta, gout and intestinal obstruction. The decoction or powder of the plant is used in whooping cough, bronchitis, palpitation of the heart, enlargement of the liver and spleen, dropsy, diseases of lungs and kidney, epilepsy and nervous disorders. A poultice of the leaves is recommended in skin diseases, piles, ulcer and haemorrhoids. A wine glass full juice of the leaves is administered in the morning with or without milk for three days to those who have been bitten by mad dogs. Root decoction is given in calculous diseases and used as an antidote to arsenic poisoning. The seed of the plant is powered and steeped in arrack or rum, yield a tincture, which is used to distroy lice. Indigo, the dye extracted from the leaves, is a soothing balm for burns and scalds, insect stings and animal bites. The synonyms visaghni and sodhani indicate the antitoxic and laxative properties of the drug nili, respectively (Aiyer and Kolammal, 1960).

Distribution: This plant is distributed in South and South East Asia, tropical Africa and is introduced in tropical America. In India, it is found almost throughout and cultivated in many parts.

Botany: Indigofera tinctoria Linn. syn. I. summatrana Gaertn, Pigmentum indicum belongs to Papilionaceae family. This is a branching shrub which grows upto 2m high. Stems and branches are green; branchlets silvery pubescent. Leaves are alternate, stipulate, imparipinnate and got 7-13 leaflets which are elliptic-oblong, membraneous,1.7x0.9cm, shortly mucronate, pale green or bluish. Flowers are small, rose-coloured in axillary racemes. Calyx 5-cleft, gamosepalous; corolla papilionaceous; stamens diadelphous; ovary sessile with a short incurved style ending in a capitate stigma. Pods are linear, cylindrical, 2-5cm long, deflexed having 8-12 seeds.

Agrotechnology: The Indian indigo requires good sunlight and grows well in hilly areas. This is usually propagated by seeds. Seeds are very small and the seed rate is 3kg/ha. Seeds require pretreatment for good germination as the seed coat is hard. Seeds are mixed with sand and ground gently to break the seed coat. An alternate method for enhancing germination is dipping the seeds in boiling water for a second. After pretreatment seeds are broadcasted. Broadcast the seeds preferably mixed with sand 2 or 3 times its volume to ensure uniform coverage. The seedbeds should be covered with straw and irrigated. Seeds germinate within 15 days. Seedlings are ready for transplanting after one month. For the land preparation, the soil is brought to fine tilth by ploughing 2 or 3 time s. Cattle manure should be applied at the rate of 10t/ha as basal dressing and incorporated into soil along with last ploughing. The best time for sowing is September-October. Weeding has to be done two times; 3 weeks after sowing and 6 weeks after sowing. Plants start flowering 2-3 months after sowing. Harvesting is done by cutting the plants at this time, at a height of about 10cm from ground level. Irrigate plants after harvest. Subsequent harvests can be made at 1.5-2 months interval. Four to five cuttings can be taken in an year depending on the growth. A few plants per plot are left without cutting to set seeds. Ripe pods are to be harvested in the early morning to prevent loss of seeds by shattering during harvest.

Properties and activity: A blue dyestuff is obtained from the indigofera which does not exist ready formed, but is produced during fermentation from another agent existing in the plant, known as indocan. Indocan is yellow amorphous of a nauseous bitter taste with an acid reaction, readily soluble in water, alcohol and ether. An artificial product indigotine is manufactured chemically and used as a substitute. Indirubin is another component of the plant.

The plant is deobstruent, alterative, antitoxic, antiasthmatic and antiepileptic. Aerial part is hypoglycaemic, CNS depressant and antitoxic. The leaves, flowers and tender shoots are considered to be cooling, demulcent and alterative. Leaf is antiinflammatory. Root and stem is laxative, expectorant, antitumourous, febrifuge, anticephalalgic, antidote for snake bite, anthelmintic and promotes growth of hair. Root is divertic. Indirubin is antineoplastic and has toxicity. Nili is antitoxic, purgative and laxative. Indigo is said to produce nausea and vomiting.... common indigo

Coomb Teak

Gmelina arborea

Verbenaceae

San: Gumbhari;

Hin:Gamari, Jugani-chukar;

Mal: Kumizhu, Kumpil;

Guj: Shewan; Pun:Gumbar; Mar: Shivanasal;

Kan: Kummuda;

Tam: Uni, Gumadi;

Tel: Gummadi;

Importance: Coomb teak, Candahar tree or Kashmeeri tree is a moderate sized, unarmed, deciduous tree which is a vital ingredient of the ”dasamula” (group of ten roots). The whole plant is medicinally very important. It promotes digestive power, improves memory, overcomes giddiness and is also used as an antidote for snake bite and scorpion sting. Roots are useful in hallucination, fever, dyspepsia, hyperdipsia, haemorrhoids, stomachalgia, heart diseases, nervous disorders, piles and burning sensation. Bark is used in fever and dyspepsia. Leaf paste is good for cephalagia and leaf juice is a good wash for foul ulcers and is also used in the treatment of gonorrhoea and cough. Flowers are recommended for leprosy, skin and blood diseases. The fruits are used for promoting the growth of hair and in anaemia, leprosy, ulcers, constipation, strangury, leucorrhoea, colpitis and lung disease.

Wood is one of the best and most reliable timber of India. It is used for making furniture, planks, carriages, printing boxes, musical instruments, shafts, axles, picture frames, jute bobbins, calipers, ship buildings, artificial limbs and stethoscopes.

In south India the bark of the tree is used by arrack manufacturers to regulate the fermentation of toddy. The plant is also grown in garden or avenues (Dey, 1988; Sivarajan and Indira, 1994).

Distribution: The plant is found wild throughout India from the foot of Himalayas to Kerala and Anadamans, in moist, semideciduous and open forests upto an altitude of 1500 m. It is also distributed in Sri Lanka and Philippines.

Botany: Gmelina arborea Roxb. Syn. Premna arborea Roth. belongs to Family Verbenaceae. It is an unarmed deciduous tree growing up to 20m height with whitish grey corky lenticellate bark, exfloliating in thin flakes. Branchlets and young parts are clothed with fine white mealy pubescence. Leaves are simple, opposite, broadly ovate, cordate, glandular, glabrous above when mature and fulvous-tomentose beneath. Flowers brownish yellow in terminal panicle. Calyx campanulate, pubescent outside and with 5 lobes. Corolla showy brownish yellow with short tube and oblique limbs. Stamens 4, didynamous and included. Ovary is 4 chambered with one ovule each; style slender ending in a bifid stigma. Fruits are fleshy ovoid drupes, orange yellow when ripe. Seeds 1 or 2, hard and oblong.

Agrotechnology: Coomb teak is a sun loving plant. It does not tolerate drought. But it grows in light frost. Rainfall higher than 2000mm and loose soil are ideal. The best method of propagation is by seeds but rarely propagated vegitatevely by stem cuttings also. Seed formation occurs in May-June. Seeds are dried well before use. They are soaked in water for 12 hours before sowing. Seed rate is 3kg/ha. Seeds are sown in nursery beds shortly before rains. Seeds germinate within one month. Seedlings are transplanted in the first rainy season when they are 7-10cm tall. Pits of size 50cm cube are made at a spacing of 3-4m and filled with sand, dried cowdung and surface soil, over which the seedlings are transplanted. 20kg organic manure is given once a year. Irrigation and weeding should be done on a regular basis. The common disease reported is sooty mould caused by Corticium salmonicolor which can be controlled by applying a suitable fungicide. The tree grows fast and may be ready for harvesting after 4 or 5 years. This plant is coppiced and traded. The roots are also used for medicinal purposes. The tree may stand up to 25 years.

Properties and activity: Roots and heart wood of Coomb teak are reported to contain gmelinol, hentriacontanol, n-octacosanol and -sitosterol. The roots contain sesquiterpenoid and apiosylskimmin, a coumarin characterised as umbelliferone-7-apiosyl glucoside and gmelofuran. The heart wood gives ceryl alcohol, cluytyl ferulate, lignans, arboreol, gmelonone, 6”-bromo isoarboreol, lignan hemiacetal and gummidiol. Leaves yield luteolin, apigenin, quercetin, hentriacontanol, -sitosterol, quercetogenin and other flavons. Fruits contain butyric acid, tartaric acid, and saccharine substances (Asolkar et al, 1992; Dey, 1988).

The roots are acrid, bitter, tonic, stomachic, laxative, galactogogue, demulcent, antibilious, febrifuge and anthelmintic. Bark is bitter, hypoglycaemic, antiviral, anticephalalgic and tonic. The leaves are demulcent, antigonorrhoeic and bechic. Flowers are sweet, refrigerant, astringent and acrid. Fruits are acrid, refrigerant, diuretic, astringent, aphrodisiac, trichogenous, alterant and tonic (Warrier et al; 1995).... coomb teak

Coriandrum Sativum

Linn.

Family: Umbelliferae; Apiaceae.

Habitat: Cultivated chiefly in Madhya Pradesh, Maharashtra, Rajasthan, Andhra Pradesh, Tamil Nadu, Karnataka and Bihar.

English: Coriander.

Ayurvedic: Dhaanyaka, Kustum- buru, Dhaanyeyaka, Dhanika, Dhanikaa, Dhaanaa, Dhaanya, Dhaniyaa, Kunati, Chhatraa, Vitunnaka.

Unani: Kishneez.

Siddha/Tamil: Kotthamalli.

Action: Stimulant, stomachic, carminative, antispasmodic, diuretic; also hypoglycaemic and anti-inflammatory. Oil—bactericidal and larvicidal. Used in China as a remedy for measles, diabetes, aerophagy and gastroenteritis.

Key application: In dyspeptic complaints, loss of appetite. (German Commission E, British Herbal Pharmacopoeia, Indian Herbal Pharmacopoeia.)

Coriander contains 0.5-1% volatile oil, consisting mainly of delta-linalool (55-74%), alpha-pinene and terpinine. It also contains flavonoids, coumarins, phthalides and phenolic acids (including caffeic and chlorogenic).

Aqueous extract of the roasted seeds contains large amounts of acetylcho- line and its precursor choline. (Choline is found useful in preventing and curing certain liver disorders.) The extract shows cholinomimetic effects experimentally.

Coriandrin, an antiviral agent, has been synthesized from the aerial parts. The plant forms an ingredient of a Pakistani herbal drug (Intellan) which is considered to be a neuro-energizer.

In Unani medicine, an infusion of fruits is also used in bleeding piles, neuralgia, cephalalgia and spermatorrhoea.

Dosage: Fruit—1-3 g powder. (API Vol. I.)... coriandrum sativum

Crinum Latifolium

Linn.

Family: Amaryllidaceae.

Habitat: Wild as well as cultivated as an ornamental.

English: Wide-leaved Crinum.

Ayurvedic: Sudarshana, Sukhadar- shana, Chakraangi, Somvalli, Madhuparnikaa.

Siddha/Tamil: Vishamoongil.

Action: Bulb—rubefacient, an- tirheumatic. Also used for piles and tubercular fistula.

The alkaloids, crinafoline and crina- folidine, have been isolated from the plant. These along with crinafoline methochloride exhibited significant tumour-inhibiting activity in vivo. The plant extract in also used in allergic condition. This activity is attributed to the presence of glucan A and phos- phatidyllycorine.

A related species, C. zeylanicum, is known as Milk-and-Wine Lily.

Dosage: Leaf, root—5-10 g paste. (CCRAS.)... crinum latifolium

Cupressus Sempervirens

Linn.

Family: Cupressaceae.

Habitat: Native to Asia Minor, Syria and North Persia. The tree is a variety only known in the cultivated state in North-West India. (Chopra RN.)

English: Mediterranean Cypress.

Ayurvedic: Suraahva.

Unani: Saro.

Siddha/Tamil: Suram, Churam.

Action: Tincture—vasoconstrictor, antiseptic, sedative, antispasmodic, diuretic. Used for cough, cold, bronchitis, varicose veins, piles, menopausal cramps, leg-cramps. Essential oil—used only externally. Used in aromatherapy for massage (10 drops in 2 teaspoonful of almond oil).

The essential oil from the plant gave 73 compounds; major compound was alpha-pinene (47.00-52.76%); among others—D-camphane, D-silvestren, p- cymene, L-cadinenes, cedrol, terpine- ol, acetyl-and isovalerianyl monoter- pene ester.

No longer taken internally as a diluted essential oil. Medicinal parts are cones, branches and oil.... cupressus sempervirens

Cynodon Dactylon

Pers.

Family: Gramineae; Poaceae.

Habitat: Throughout India up to 3,000 m.

English: Bermuda Grass, Bahama Grass, Couch Grass.

Ayurvedic: Duurvaa, Bhaargavi, Shatvalli, Shatparvaa, Tiktaparvaa, Shatviryaa, Sahastravirya, Shitaa, Anantaa, Golomi.

Unani: Duub.

Siddha/Tamil: Arugampallu.

Action: The grass is a reputed as a remedy in epitaxis, haematuria, inflammed tumours, whitlows fleshy excrescences, cuts, wounds, bleeding piles, cystitis, nephritis and in scabies and other skin diseases. It is credited with astringent, diuretic, antidiarrhoeal, anticatarrhal, styptic and antiseptic properties. The Ayurvedic Pharmacopoeia ofIn- dia recommended the dried fibrous root in menorrhagia, metrorrhagia and burning micturation.

Phenolic phytotoxins—ferulic, sy- ringic, p-coumaric, vanillic, p-hydro- xybenzoic and O-hydroxyphenyl acetic acids, are reported from the plant. The leaves contain tricin, flavone C- glycosides and a flavonoid sulphate.

Dosage: Whole plant—10-20 ml juice (API Vol. IV.); root—5-10 ml juice (API Vol. III.)... cynodon dactylon

Delphinium Denudatum

Wall.

Synonym: D. pauciflorum Royle.

Family: Ranunculaceae.

Habitat: The temperate Himalayas from Kashmir to Kumaon at altitudes of 2,400-3,600 m.

English: Larkspur. Ayurvedic: Nirvishaa, Nirvishi. (Kyllinga triceps Rottb. is used as a substitute for Nirvishaa.)

Unani: Jadwaar Khataai, Maatiryaaq.

Folk: Root—astringent, vulnerary, deobstruent, alterative. Used for painful piles, muscular atrophy, gout and as a nervine tonic. Also used as an adulterant for aconite.

Oral administration of the aqueous extract of the plant to rats with CCl4- induced hepatotoxicity revealed hepa- toprotective property of the plant.

The roots contain campesterol, stig- masterol, sitosterol, cholesterol, delta- avenasterol and alkaloids including de- nudatine, denudatidine, condelphine, talatizidine and iso-talatizidine.... delphinium denudatum

Derris Uliginosa

Benth. Derris indica (Lamk.) Bennet.

Synonym: Pongamia pinnata Pierre.

Family: Fabaceae.

Habitat: Native to the Western Ghats. Found all over India on the banks of rivers and streams.

English: Indian Beech. Pongamia oil tree.

Ayurvedic: Naktmaal, Guchpush- pak, Ghritpuur, Udkirya, Karanja.

Siddha/Tamil: Pungu.

Action: Used for skin diseases— eczema, scabies, leprosy, and for ulcers, tumours, piles, enlargement of spleen, vaginal and urinary discharges. Juice of root—used for closing fistulous sores and cleaning foul ulcers. Flowers— used in diabetes. Powder of seeds— used for whooping and irritating coughs of children. Seed oil—used in cutaneous affections, herpes and scabies.

The tree is rich in flavonoids and related compounds. These include simple flavones, furanoflavonoids, chro- menoflavones, chromenochalcones, coumarones, flavone glucosides, sterols, triterpenes and a modified pheny- lalanine dipeptide.

Synonym: D. trifoliate Lour.

Family: Fabaceae.

Habitat: Costal forests of India and the Andamans.

Folk: Paan-lataa (Bengal), Kitani (Maharashtra).

Action: Stimulant, antispasmodic, counter-irritant. Bark—alterative in rheumatism. An oil prepared from the plant is used externally as an embrocation.

The roots contain dehydrorotenone, lupeol and a ketone. Bark contains 9.3% tannic acid. Stems contain tan- nic acid, hexoic, arachidic and stearic acids, ceryl alcohol, isomerides of cholesterol, potassium nitrate, gums and resins.... derris uliginosa

Dioscorea Bulbifera

Linn.

Synonym: D. sativa Thumb auct. non L.D. versicolor Buch.-Ham ex Wall.

Family: Dioscoreaceae.

Habitat: Throughout tropical India, at 1,500-2,100 m.

English: Patoto Yam, Bulb-bearing Yam, Air Potato, Dog Yam.

Ayurvedic: Vaaraahi, Vaaraahikan- da, Grshti, Banaaalu, Suraalu, Raktaalu. Substitute for Vriddhi.

Unani: Baraahikand.

Siddha/Tamil: Kodi-kilangu, Pannu-kilangu.

Action: Dried and pounded tubers are used as an application for swellings, boils and ulcers; roasted tubers are used in dysentery, piles, venereal sores. Leaf—febrifuge.

The raw tubers are bitter due to the presence of furanoid norditerpenes (they lose their bitterness on roasting and are then eaten). The wild tubers contain nearly 83% starch and possess hunger-suppressing property. They contain certain poisonous alkaloids.

The rhizomes afforded D-sorbitol, furanoid norditerpenes—diosbulbins A-D, 2,4,6,7-tetrahydroxy-9,10-dihy- drophenanthrene and 2,4,5,6,-tetra- hydroxyphenanthrene, diosgenin, lucein, neoxanthine, violaxanthin, zeax- anthin, auroxanthin and cyrptoxan- thin.... dioscorea bulbifera

Eleocharis Dulcis

Trin.

Synonym: E. plantaginea R. Br. E. tuberosa Schult.

Family: Cyperaceae.

Habitat: Widely cultivated in China. Sold in Kolkata under the name Singapuri Keysur.

English: Chinese Water Chestnut.

Ayurvedic: Shringaataka (substitute), Kasheruka (substitute).

Action: Tuber—antidysenteric, antileucorrhoeic, antibacterial.

The juice expressed from the tuber shows antibiotic activity against Staphylococcus aureus, E. coli and Aer- obacter aerogenes. The antibiotic principle has been designated as puchiin.

In ethanolic extract, hexacosanoic acid, 5 alpha-stigmastane-3, 6-dione, betulin and tricin were present. It also contained beta-sitosterol and stigmas- terol. applied to ulcers and eczema. Roots—given to patients with heart and liver affections; topically in rheumatism. Root and leaf— used in dysuria and other urethral complaints. An infusion of the whole plant is used to stimulate diuresis, reduce fever and to eliminate bladder stones. The decoction is also used in peptic ulcers, swelling or pain in stomach. Plant is also used in piles and scabies.

The plant contains germacranolide dilactones. Hydroxylated germacano- lides, molephantin and molephantinin, exhibited cytotoxic and antitumour properties.

The plant also gave epifriedelanol, lupeol, stigmasterol, triacontan-l-ol and dotriacontan-l-ol.... eleocharis dulcis

Erigeron Canadensis

Linn.

Family: Compositae; Asteraceae.

Habitat: Punjab, Upper Gangetic Plain, Assam, Western Ghats and Western Himalayas.

English: Canadian Fleabane.

Ayurvedic: Jaraayupriya, Makshikaa-visha, Palit (non- classical).

Action: Astringent, haemostatic, antirheumatic, diuretic. Used for diarrhoea, kidney disorders, bronchitis and for bleeding piles, wounds, bruises. Essential oil— used in bronchial catarrh and cystitis.

The extracts of the plant gave ses- quiterpenes, beta-santalen, beta-hima- chalene, cuparene, alpha-curcumene, gamma-cadinene.

The petroleum ether and ethanolic extracts of aerial parts exhibit significant anti-inflammatory activity.

Aqueous extract of powdered plant produces fall in blood pressure, depresses the heart and increases respiration in animals.

The essential oil, obtained from aerial parts in Japan, is found to contain 47 volatile compounds of which 91.0% are terpenoids. The leaves contain cumu- lene derivatives.

For preparing plant extract as a drug, the volatile oil is removed from a hot aqueous extract and the residue is filtered and concentrated to 24% or 60% of dry matter content. The 6% dry matter extract contains flavones 0.83, tannins 0.52, reducing sugars 6.37 and total sugars 12.6%. The extract is anti- inflammatory, analgesic, bactericidal and fungicidal.... erigeron canadensis

Ficus Religiosa

Linn.

Family: Moraceae.

Habitat: Sub-Himalayan tracts, West Bengal, Central and South India; planted throughout India as an avenue tree.

English: Peepal, Bot-tree.

Ayurvedic: Ashvattha, Bodhidru, Bodhivrkisha, Sebya, Chalapa- tra, Gajabhaksha, Kshiradruma, Peeppal.

Unani: Peepal.

Siddha/Tamil: Arasu, Ashvatham.

Action: Bark—astringent, antiseptic, alterative, laxative, haemostatic, vaginal disinfectant (used in diabetes, diarrhoea, leucorrhoea, menorrhagia, nervous disorders; also in skin diseases.) Applied externally on unhealthy ulcers and wounds. Leaves and twigs— laxative.

The bark contains beta-sitosteryl-D- glucoside. Vitamin K, n-octacosanol, methyl oleanolate, lanosterol, stigmas- terol, lupen-3-one are reported from the stem bark.

A hypoglycaemic response is reported for beta-sitosterol-D-glucoside obtained from the bark.

Aerial roots are given to women, also used in prescriptions, for inducing conception. The dried fruits are used as a uterine tonic.

The fruits contain 4.9% protein having the essential amino acids, isoleu- cine and phenylalanine. The chloroform extract of fruits exhibited anti- tumour and antibacterial activities in bioassays.

Various plant parts are included in formulations used for menorrha- gia, metrorrhagia, blood dysentery, bleeding piles, haematuria and haemorrhages.

Dosage: Bark, fruit—50-100 ml decoction. (CCRAS.)... ficus religiosa

Glinus Lotoides

Linn.

Synonym: Mollugo lotoides (L.) O. Kuntze. M hirta Thumb.

Family: Molluginaceae; Aizoaceae.

Habitat: Throughout the plains and lower ghats of India in river beds.

Siddha/Tamil: Siru seruppadai. Folk: Gandhi-buuti.

Action: Plant—antidiarrhoeal, antibilious, diuretic. Decoction is given in piles.

The plant gave pentacyclic triterpe- noid sapogenins; a mixture ofbeta-and gamma-sitosterol, oleanolic acid, mol- lugogenol and its constituents. Aerial parts gave vitexin and vicenin.... glinus lotoides

Gloriosa Superba

Linn.

Habitat: Throughout tropical India, up to 2,350 m on the hills.

English: Glory Lily, Super Lily, Tiger's Claws.

Ayurvedic: Laangali, Laangaliki, Laangalaki, Laanglaahva, Indra- pushpi, Agnishikhaa, Anantaa, Vishaalyaa, Halini, Sirikramaa, Shukrapushpikaa, Vahnimukhi, Garbhanut, Garbhapaatani. Kali- haari (Costus specious Koen., is also used as Kalihaari), Kalikaari.

Siddha/Tamil: Kalappankizhangu.

Action: Tuberous root—anti- inflammatory, alterative, an- thelmintic, antileprotic. Used for piles, swollen joints, parasitical affections of skin. Fresh juice of plant—uterine stimulant.

The root contain colchicine 0.230.3%. Colchicine and its derivatives are present in tubers, seeds and flowers.

The seeds are used as raw material for preparing drugs for gout. They are considered a rich source of colchicine and gloriosine.

The herb is a gastrointestinal irritant.

Dosage: Detoxified tuberous root— 125-250 mg. (API Vol. III.)... gloriosa superba

Gymnema

Gymnema sylvestre

Asclepiadaceae

San: Mesasrngi, Madhunasini;

Hin: Gudmar, Merasimgi;

Ben: Merasingi;

Mal: Chakkarakolli, Madhunasini;

Tam: Sirukurumkay, Sakkaraikkolli;

Kan: Kadhasige;

Tel: Podapatra; Mar: Kavali

Importance: Gymnema, Australian Cowplant, Small Indian Ipecacuanha or Periploca of the woods is a woody climber. It is reported to cure cough, dyspnoea, ulcers, pitta, kapha and pain in the eyes. The plant is useful in inflammations, hepatosplenomegaly, dyspepsia, constipation, jaundice, haemorrhoids, strangury, renal and vesical calculi, helminthiasis, cardiopathy, cough, asthma, bronchitis, intermittent fever, amenorrhoea, conjuctivitis and leucoderma. The fresh leaves when chewed have the remarkable property of paralysing the sense of taste for sweet and bitter substance for some time (Warrier et al, 1995). The drug is described as a destroyer of madhumeha (glycosuria) and other urinary disorders. Root has long been reputed as a remedy for snakebite. Leaves triturated and mixed with castor oil are applied to swollen glands and enlargement of internal viscera as the liver and spleen (Nadkarni, 1954). The drug is used to strengthen the function of heart, cure jaundice, piles, urinary calculi, difficult micturition and intermittent fevers (Sharma,1983). The drug enters into the composition of preparations like Ayaskrti, Varunadi kasaya, Varunadighrtam, Mahakalyanakaghrtam, etc. They suppress the activity of taste of tongue for sweet taste and for this reason it was considered that it destroys sugar, hence the name Madhunashini or Gurmar and has been prescribed as an anti-diabetic. The crude drug as well as its dried aqueous extract is mainly used in bronchial troubles.

Distribution: It is a tropical climber. It mainly grows in Western Ghats, Konkan, Tamil Nadu and some parts of Bihar. The plant is cultivated in plains of India but the drug is mainly important from Afghanistan and Iran.

Botany: Gymnema sylvestre (Retz.)R. Br. syn. Asclepias germinata Roxb. belonging to the family Asclepiadaceae is a large, woody much branched climber with pubescent young parts. Leaves are simple, opposite, elliptic or ovate, more or less pubescent on both sides, base rounded or cordate. Flowers are small, yellow and arranged in umbellate cymes. Fruits are slender and follicles are upto 7.5cm long (Warrier et al, 1995).

Two allied species, G. hirsutum found in Bundelkh and Bihar and Western Ghats and G. montanum growing wild in Eastern Ghats and Konkan are also used for the same purpose and are also called “Gurmar” (Thakur et al, 1989).

Agrotechnology: The plant can be propagated both by seeds and stem cuttings. Seedlings are to be raised in polybags. Pits of size 50cm cube are to be taken, filled with 10kg dried cowdung or FYM and covered with topsoil. On these pits about 3-4 months old seedlings are to be transplanted from polybags. Trailing can be facilitated by erecting poles and tying the plants to the poles. The plant will attain good spread within one year. Regular weeding, irrigation and organic manure application are beneficial. The plant is not attacked by any serious pests or diseases. Leaves can be collected from the first year onwards at an internal of one week. This can be continued for 10-12 years. Fresh or dried leaves can be marketed (Prasad et al, 1997).

Properties and activity: Nonacosane and hentriacontane were isolated from the hexane extract of leaves. An attempt to isolate nitrogenous compounds led to the isolation of amino acids such as leucine, iso-leucine, valine, allanine and - amynobutyric acid. Isolation of trimethyl amine oxide was of particular interest. An alkaloid gynamine which is a trace constituent was isolated and identified (Sinsheimer et al, 1967). Antisweet constituent of the leaves has been found to be a mixture of triterpene saponins. These have been designated as gymnemic acids A,B,C and D which have the gymnemagenin and gymnestrogenins as the aglycones of gymnemic acid A and B and gymnemic acid C and D respectively. These are hexahydroxy triterpenes the latter being partially acylated. The sugar residues are glucuronic acid and galacturonic acid while ferulic and angelic acids have been attached as the carboxylic acid.

Chewing of leaves reduces sensitivity to sweet substances. Effects of gymnema extracts had been variable. While verifying the effect of G. sylvestre leaves on detoxification of snake venom, it has been reported that a toxic component of venom ATP and gymnemate bind at the same site inhibiting venom ATP-ase. The active principles which have been identified as glycosides (7 gymnemic acids) suggest that the topical and selective anaesthetic effect of the plant might result from the competition of the receptor sites between glycosides and the sweet substances (Warren et al, 1969). The leaves are antidiabetic and insulinotropic. Gymnemic acid is antiviral. The plant is bitter, astringent, acrid, thermogenic, antiinflammatory, anodyne, digestive, liver tonic, emetic, diuretic, stomachic, stimulant, anthelmintic, alexipharmic, laxative, cardiotonic, expectorant, antipyretic and uterine tonic.... gymnema

Hemidesmus Indicus

(L.) R. Br.

Synonym: Periploca indica Linn.

Family: Asclepiadaceae, Periplo- caceae.

Habitat: Throughout India; common in Bengal, Maharashtra and extending to Travancore.

English: Indian Sarsaparilla (white var.). Sarsaparilla root is equated with Smilax sp. in Western herbal.

Ayurvedic: Shveta Saarivaa, Anant- muula, Gopi, Gopaa, Gopakanyaa, Gopavalli, Gopasutaa, Krishodari, Sphotaa, Utpalsaarivaa, Kapuuri, Dugdhgarbhaa.

Unani: Ushbaa Hindi.

Siddha/Tamil: Nannaari, Sugan- thipala.

Action: Blood purifier, antisyphilitic, antileucorrhoeic, galactogenic, antidiarrhoeal, antirheumatic, febrifuge, alterative. Roots used against gonorrhoea, leucoderma, bleeding piles, jaundice and dysentery.

Key application: Smilax sp.—in skin diseases and urinary infections. (German Commission E included Smilax sp. among unapproved herbs.)

Hemidesmus indicus does not contain the same saponins or other principal constituents which are found in sarsaparilla. (Tyler's Honest Herbal.)

The root contains coumarino-lig- noids, hemidesmine, hemidesmin-1, 2. The stem contains pregnane glyco- sides, hemidine, hemidescine, emidine and indicine, a triterpene lactone, a lu- panone, besides lupeol acetate, sitos- terol and hexadecanoic acid and several hydroxy- methoxybenzaldehydes.

Aqueous extract of the root is bacteriostatic against Mycobacterium leprae.

Dosage: Root—20-30 g for decoction. (API Vol. I.) palmitoleic, stearic, oleic, linoleic and arachidic. Pyrocatechol, tannins, fla- vonoids and amino acids were also present.... hemidesmus indicus

Holarrhena Antidysenterica

(Linn.) Wall.

Synonym: H. pubescens (Buch.- Ham.) Wall. ex G. Don.

Family: Apocynaceae.

Habitat: The tropical Himalayas, going up to an altitude of 1,100 m. Also found throughout many forests of India, in Travancore, Assam and Uttar Pradesh.

English: Easter tree, Ivory tree, Tellicherry Bark.

Ayurvedic: Kutaja, Girimallikaa, Kaalinga, Kalingaka, Indravrik- sha, Shakra, Vatsa, Vatsaka, Shakraahvya. Indrayava, Indrabija, Vatsabija (seed). Kurchi (bark).

Unani: Inderjo talkh, Teewaaj-e- Khataai.

Siddha/Tamil: Kudasappaalai-pattai, -vidai (bark, seed).

Action: Root and bark—used in amoebic dysentery. Bark—astringent, anthelmintic, amoebicidal, diuretic. Used in colic, dyspepsia, piles, diseases of the skin and spleen. Seed—antibilious. Used for promoting conception, also for toning up vaginal tissues after delivery.

The bark contains the alkaloids, regholarrhenine-A, -B, -C, -D, -E and -F; pubescine, norholadiene, pubes- cimine, kurchinin, kurchinine, kur- chinidine, holarrifine, holadiene, kurchilidine, kurchamide, kurcholes- sine, kurchessine, conessine, cones- simine and isoconessimine, and the steroidal compounds kurchinicin and holadyson.

The alkaloid conessine is used as a therapeutic drug for the treatment of dysentery and helminthic disorders. Conessine and conimine inhibited the growth of Shigella sonnei, S. flexneri and Salmonella enteritidis strains in vitro. In chronic amoebiasis, Bi-iodide compound of total alkaloids, given orally, compare favourably with emetine Bi-iodide.

The plant possesses potent immuno- stimulant property.

The Kurchi seeds are sold as a substitute for Strophanthus sp. seeds in Indian market. (Seeds of Strophanthus sp. contain a toxic glucoside, strophan- thin, and are poisonous.)

Dosage: Stem bark—20-30 g for decoction. (API Vol. I); seed—3- 6 g powder; 20-30 g for decoction. (API Vol. III.)... holarrhena antidysenterica

Indigofera Tinctoria

Linn.

Family: Fabaceae.

Habitat: Cultivated in many parts of India.

English: Indigo.

Ayurvedic: Nilikaa, Nilaa, Nila, Nili, Nilini, Nilapushpa, Ranjani, Shaaradi, Tutthaa.

Unani: Habb-ul-Neel.

Siddha/Tamil: Nili, Averi, Asidai, Attipurashadam.

Action: Plant—antiseptic, hepato- protective, hypoglycaemic, nervine tonic. Used in enlargement of liver and spleen, skin diseases, leucoder- ma, burns, ulcers, piles, nervous disorders, epilepsy, asthma, lumbago, gout. Leaf—anti-inflammatory. Used in blennorrhagia. Root— diuretic. Used in hepatitis. Root and stem—laxative, expectorant, febrifuge, anticephalalgic, anti- tumour, anthelmintic, promote growth of hair.

The Ayurvedic Pharmacopoeia of India recommends the use of dried whole plant in phobia, delusion and disturbed mental state.

Indicine (5-15 mg/g, dry basis) and the flavonoids, apigenin, kaempferol, luteolin and quercetin are present in various plant parts, maximum in the leaves and minimum in the roots (however quercetin was minimum in leaves). The presence of coumarins, cardiac glycosides, saponins and tannins is also reported.

Alcoholic extract of the aerial parts showed hepatoprotective activity in experimental animals against CCl4- induced hepatic injury. The extract increased bile flow and liver weight in rats. The alcoholic extract also exhibited hypoglycaemic activity in rats.

The plant is used in the treatment of endogenous depression. It contains appreciable amounts of conjugated in- doxyl (indican). The use of indigo and its constituents, indirubin and indigotin, prevents allergic contact dermatitis. The 8 weeks old tissues in culture contain maximum histamine content (5.0 mg/g dry weight).

Dosage: Dried leaf—50-100 g for decoction; root—48 g for decoction (API Vol. II); whole plant—10-20 g for decoction. (API Vol. III.)... indigofera tinctoria

Inadequate Intake Of Iron

The daily requirement of iron for an adult is 12 mg, and 15–20 mg for an adult woman during pregnancy. This is well covered by an ordinary diet, so that by itself it is not a common cause. But if there is a steady loss of blood, as a result of heavy menstrual loss or ‘bleeding piles’, the intake of iron in the diet may not be su?cient to maintain adequate formation of haemoglobin.

Symptoms These depend upon whether the anaemia is sudden in onset, as in severe haemorrhage, or gradual. In all cases, however, the striking sign is pallor, the depth of which depends upon the severity of the anaemia. The colour of the skin may be misleading, except in cases due to severe haemorrhage, as the skin of many Caucasian people is normally pale. The best guide is the colour of the internal lining of the eyelid. When the onset of the anaemia is sudden, the patient complains of weakness and giddiness, and loses consciousness if he or she tries to stand or sit up. The breathing is rapid and distressed, the pulse is rapid and the blood pressure is low. In chronic cases the tongue is often sore (GLOSSITIS), and the nails of the ?ngers may be brittle and concave instead of convex (koilonychia). In some cases, particularly in women, the Plummer-Vinson syndrome is present: this consists of di?culty in swallowing and may be accompanied by huskiness; in these cases glossitis is also present. There may be slight enlargement of the SPLEEN, and there is usually some diminution in gastric acidity.

CHANGES IN THE BLOOD The characteristic change is a diminution in both the haemoglobin and the red cell content of the blood. There is a relatively greater fall in the haemoglobin than in the red cell count. If the blood is examined under a microscope, the red cells are seen to be paler and smaller than normal. These small red cells are known as microcytes.

Treatment consists primarily of giving suf?cient iron by mouth to restore, and then maintain, a normal blood picture. The main iron preparation now used is ferrous sulphate, 200 mg, thrice daily after meals. When the blood picture has become normal, the dosage is gradually reduced. A preparation of iron is available which can be given intravenously, but this is only used in cases which do not respond to iron given by mouth, or in cases in which it is essential to obtain a quick response.

If, of course, there is haemorrhage, this must be arrested, and if the loss of blood has been severe it may be necessary to give a blood transfusion (see TRANSFUSION – Transfusion of blood). Care must be taken to ensure that the patient is having an adequate diet. If there is any underlying metabolic, oncological, toxic or infective condition, this, of course, must be adequately treated after appropriate investigations.

Megaloblastic hyperchromic anaemia There are various forms of anaemia of this type, such as those due to nutritional de?ciencies, but the most important is that known as pernicious anaemia.

PERNICIOUS ANAEMIA An autoimmune disease in which sensitised lymphocytes (see LYMPHOCYTE) destroy the PARIETAL cells of the stomach. These cells normally produce INTRINSIC FACTOR, the carrier protein for vitamin B12 (see APPENDIX 5: VITAMINS) that permits its absorption in the terminal part of the ILEUM. Lack of the factor prevents vitamin B12 absorption and this causes macrocytic (or megaloblastic) anaemia. The disorder can affect men and women, usually those over the age of 40; onset is insidious so it may be well advanced before medical advice is sought. The skin and MUCOSA become pale, the tongue is smooth and atrophic and is accompanied by CHEILOSIS. Peripheral NEUROPATHY is often present, resulting in PARAESTHESIA and numbness and sometimes ATAXIA. A rare complication is subacute combined degeneration of the SPINAL CORD.

In 1926 two Americans, G R Minot and W P Murphy, discovered that pernicious anaemia, a previously fatal condition, responded to treatment with liver which provides the absent intrinsic factor. Normal development requires a substance known as extrinsic factor, and this depends on the presence of intrinsic factor for its absorption from the gut. The disease is characterised in the blood by abnormally large red cells (macrocytes) which vary in shape and size, while the number of white cells (LEUCOCYTES) diminishes. A key diagnostic ?nd is the presence of cells in the BONE MARROW.

Treatment consists of injections of vitamin B12 in the form of hydroxocobalamin which must be continued for life.

Aplastic anaemia is a disease in which the red blood corpuscles are very greatly reduced, and in which no attempt appears to be made in the bone marrow towards their regeneration. It is more accurately called hypoplastic anaemia as the degree of impairment of bone-marrow function is rarely complete. The cause in many cases is not known, but in rather less than half the cases the condition is due to some toxic substance, such as benzol or certain drugs, or ionising radiations. The patient becomes very pale, with a tendency to haemorrhages under the skin and mucous membranes, and the temperature may at times be raised. The red blood corpuscles diminish steadily in numbers. Treatment consists primarily of regular blood transfusions. Although the disease is often fatal, the outlook has improved in recent years: around 25 per cent of patients recover when adequately treated, and others survive for several years. In severe cases promising results are being reported from the use of bone-marrow transplantation.

Haemolytic anaemia results from the excessive destruction, or HAEMOLYSIS, of the red blood cells. This may be the result of undue fragility of the red blood cells, when the condition is known as congenital haemolytic anaemia, or of acholuric JAUNDICE.

Sickle-cell anaemia A form of anaemia characteristically found in people of African descent, so-called because of the sickle shape of the red blood cells. It is caused by the presence of the abnormal HAEMOGLOBIN, haemoglobin S, due to AMINO ACID substitutions in their polypeptide chains, re?ecting a genetic mutation. Deoxygenation of haemoglobin S leads to sickling, which increases the blood viscosity and tends to obstruct ?ow, thereby increasing the sickling of other cells. THROMBOSIS and areas of tissue INFARCTION may follow, causing severe pain, swelling and tenderness. The resulting sickle cells are more fragile than normal red blood cells, and have a shorter life span, hence the anaemia. Advice is obtainable from the Sickle Cell Society.... inadequate intake of iron

Indian Beech

Pongamia pinnata

Papilionaceae

San: Karanj;

Hin: Karanja, Dittouri;

Ben: Dehar karanja;

Mal: Ungu, Pongu; Guj, Mar, Pun: Karanj;

Kan: Hongae;

Tel: Kangu;

Tam: Puggam; Ass: Karchaw; Ori: Koranjo

Importance: Indian beech, Pongam oil tree or Hongay oil tree is a handsome flowering tree with drooping branches, having shining green leaves laden with lilac or pinkish white flowers. The whole plant and the seed oil are used in ayurvedic formulations as effective remedy for all skin diseases like scabies, eczema, leprosy and ulcers. The roots are good for cleaning teeth, strengthening gums and in gonorrhoea and scrofulous enlargement. The bark is useful in haemorhoids, beriberi, ophthalmopathy and vaginopathy. Leaves are good for flatulence, dyspepsia, diarrhoea, leprosy, gonorrhoea, cough, rheumatalgia, piles and oedema. Flowers are given in diabetes. Fruits overcomes urinary disease and piles. The seeds are used in inflammations, otalgia, lumbago, pectoral diseases, chronic fevers, hydrocele, haemorrhoids and anaemia. The seed oil is recommended for ophthalmia, haemorrhoids, herpes and lumbagoThe seed oil is also valued for its industrial uses. The seed cake is suggested as a cheap cattle feed. The plant enters into the composition of ayurvedic preparations like nagaradi tailam, varanadi kasayam, varanadi ghrtam and karanjadi churna.

It is a host plant for the lac insect. It is grown as a shade tree. The wood is moderately hard and used as fuel and also for making agricultural implements and cart- wheels.

Distribution: The plant is distributed throughout India from the central or eastern Himalaya to Kanyakumari, especially along the banks of streams and rivers or beach forests and is often grown as an avenue tree. It is distributed in Sri Lanka, Burma, Malaya, Australia and Polynesia.

Botany: Pongamia pinnata (Linn.) Pierre syn. P. glabra Vent., Derris indica (Lam.) Bennet, Cystisus pinnatus Lam. comes under family Papilionaceae. P. pinnata is a moderate sized, semi -evergreen tree growing upto 18m or more high, with a short bole, spreading crown and greyish green or brown bark. Leaves imparipinnate, alternate, leaflets 5-7, ovate and opposite. Flowers lilac or pinkish white and fragrant in axillary recemes. Calyx cup-shaped, shortly 4-5 toothed, corolla papilionaceous. Stamens 10 and monadelphous, ovary subsessile, 2-ovuled with incurved, glabrous style ending in a capitate stigma. Pod compressed, woody, indehiscent, yellowish grey when ripe varying in size and shape, elliptic to obliquely oblong, 4.0-7.5cm long and 1.7-3.2cm broad with a short curved beak. Seeds usually 1, elliptic or reniform, wrinkled with reddish brown, leathery testa.

Agrotechnology: The plant comes up well in tropical areas with warm humid climate and well distributed rainfall. Though it grows in almost all types of soils, silty soils on river banks are most ideal. It is tolerant to drought and salinity. The tree is used for afforestation, especially in watersheds in the drier parts of the country. It is propagated by seeds and vegetatively by rootsuckers. Seed setting is usually in November. Seeds are soaked in water for few hours before sowing. Raised seed beds of convenient size are prepared, well rotten cattle manure is applied at 1kg/m2 and seeds are uniformly broadcasted. The seeds are covered with a thin layer of sand and irrigated. One month old seedlings can be transplanted into polybags, which after one month can be planted in the field. Pits of size 50cm cube are dug at a spacing of 4-5m, filled with top soil and manure and planted. Organic manure are applied annually. Regular weeding and irrigation are required for initial establishment. The trees flower and set fruits in 5 years. The harvest season extends from November- June. Pods are collected and seeds are removed by hand. Seed, leaves, bark and root are used for medicinal purposes. Bark can be collected after 10 years. No serious pests and diseases are reported in this crop.

Properties and activity: The plant is rich in flavonoids and related compounds. Seeds and seed oil, flowers and stem bark yield karanjin, pongapin, pongaglabrone, kanugin, desmethoxykanugin and pinnatin. Seed and its oil also contain kanjone, isolonchocarpin, karanjachromene, isopongachromene, glabrin, glabrachalcone, glabrachromene, isopongaflavone, pongol, 2’- methoxy-furano 2”,3”:7,8 -flavone and phospholipids. Stem-bark gives pongachromene, pongaflavone, tetra-O-methylfisetin, glabra I and II, lanceolatin B, gamatin, 5-methoxy- furano 2”,3”:7,8 -flavone, 5-methoxy-3’,4’-methelenedioxyfurano 2”,3”:7,8 -flavone and - sitosterol. Heartwood yields chromenochalcones and flavones. Flowers are reported to contain kanjone, gamatin, glabra saponin, kaempferol, -sitosterol, quercetin glycocides, pongaglabol, isopongaglabol, 6-methoxy isopongaglabol, lanceolatin B, 5-methoxy-3’,4’- methelenedioxyfurano 8,7:4”,5” -flavone, fisetin tetramethyl ether, isolonchocarpin, ovalichromene B, pongamol, ovalitenon, two triterpenes- cycloart-23-ene,3 ,25 diol and friedelin and a dipeptide aurantinamide acetate.

Roots and leaves give kanugin, desmethoxykanugin and pinnatin. Roots also yield a flavonol methyl ether-tetra-O-methyl fisetin. The leaves contain triterpenoids, glabrachromenes I and II, 3’-methoxypongapin and 4’-methoxyfurano 2”,3”:7,8 -flavone also. The gum reported to yield polysaccharides (Thakur et al, 1989; Husain et al, 1992).

Seeds, seed oil and leaves are carminative, antiseptic, anthelmintic and antirheumatic. Leaves are digestive, laxative, antidiarrhoeal, bechic, antigonorrheic and antileprotic. Seeds are haematinic, bitter and acrid. Seed oil is styptic and depurative. Karanjin is the principle responsible for the curative properties of the oil. Bark is sweet, anthelmintic and elexteric.... indian beech

Ipomoea Quamoclit

Linn.

Synonym: Quamoclitpinnata Bojer.

Family: Convolvulaceae.

Habitat: Native to tropical America; grown as an ornamental.

English: Cypress Vine, Indian Pink.

Ayurvedic: Kaamalataa.

Siddha/Tamil: Kembumalligai, Mayirmanikkam.

Folk: Sitaakesh.

Action: Powdered root is given as a sternutatory. Pounded leaves are applied to bleeding piles.

The leaves and stems are reported to contain small amounts of alkaloids. Traces of hydrocyanic acid are present also in roots, stems and flowers.... ipomoea quamoclit

Lamium Album

Linn.

Family: Labiatae; Lamiaceae.

Habitat: West Himalayas from Kashmir to Kumaon.

English: White Dead Nettle, Archangel.

Action: Haemostatic (particularly on the uterus), astringent, diuretic, anti-inflammatory, antispasmodic, expectorant. Used for menorrhagia, leucorrhoea, cystitis, prostatitis, bleeding piles, diarrhoea, irritable bowel and respiratory catarrh.

Key application: Internally, for catarrh of the upper respiratory passages; externally, for mild, superficial inflammation of the skin. (German Commission E.) Flowers have been recommended for teas and other galenical preparations for internal applications, rinses, baths and moist compresses. As astringent. (The British Herbal Pharmacopoeia.)

The herb contains iridoid monoterpenes; triterpene saponins; caffeic acid derivatives; flavonoids based on kaem- pferol; tannins (mainly catechins). The plant also gave a carbocyclic iridoid, caryoptoside; besides lambalbide, al- bosides A and B (iridoid monoter- penes).... lamium album

Lepidium Sativum

Linn.

Family: Curciferace, Brassicaceae.

Habitat: Native to West Asia; cultivated throughout India as a salad plant.

English: Garden Cress, Water Cress.

Ayurvedic: Chandrashuura, Chan- drikaa, Vaas-pushpaa, Pashume- hankaarikaa, Nandini, Suvaasaraa, Aashaalim.

Unani: Habb-ul-rashaad, Tukh-e- Taratezak, Haalim, Sipandaan.

Siddha/Tamil: Alivirai.

Action: Used in asthma, bronchial affections and bleeding piles. Seeds—lactagogue, diuretic, and emmenagogue. Used for treating skin disorders, fever, amoebic dysentery and asthma. Leaf— stimulant, antiscorbutic, diuretic. Roots—used in secondary syphilis and in tenesmus.

The Ayurvedic Pharmacopoeia of India recommends the use of dried seeds, in powder form, in gout.

The seeds are a good source of iron, but its bioavailability is poor (5.4% of total iron). They are used for rapid healing ofbone fractures. The ethano- lic extract of seeds significantly increased collagen synthesis and its deposition at bone fracture portion in the treated rats. The tensile strength of the broken tibiae also increased.

The seeds contain an alkaloid (0.19%), glucotropaeolin, sinapin (cho- line ester of sinapic acid), sinapic acid, mucilaginous matter (5%) and uric acid (0.108 g/kg). The seed oil exhibits pronounced oestrogenic activity.

The seed mucilage allays the irritation of the mucous membrane of intestines in dysentery and diarrhoea. It consists of a mixture of cellulose (18.3%) and uronic acid-containing polysaccharides; acid hydrolysis yield L-arabinose, D-galactose, L-rhamnose, D-glacturonic acid and D-glucose.

The plant contains pantothenic acid, pyridoxin and rutin. Ethanolic extract of the plant showed antiviral activity against rinderpest virus.

Dosage: Seed—3-6 g powder. (API, Vol. I.)... lepidium sativum

Leucas Cephalotes

(Roth.) Spreng.

Family: Labiatae; Lamiaceae.

Habitat: Throughout the greater part of India, as a weed, ascending up to 1,800 m in the Himalayas.

Ayurvedic: Dronpushpi, Katumbaa. Siddha/Tamil: Tumbai. Folk: Guumaa, Dhurpi saaga, Halkusa (bigger var.), Tumbaa.

Action: Plant—stimulant, diaphoretic, antiseptic (fresh juice is used in scabies), insecticidal. Flowers— a syrup is used as a domestic remedy for coughs and colds. Dry leaves along with tobacco (1: 3) are smoked to treat bleeding as well as itching piles.

The Ayurvedic Pharmacopoeia ofIn- dia indicated the use of the dried whole plant in jaundice, inflammations, cough, bronchial asthma and intermittent fever.

The plant contains beta-sitosterol glycoside and traces of an alkaloid.

Dosage: Whole plant—5-10 ml juice; 1-3 g powder. (API, Vol. II.)... leucas cephalotes

Leadwort

Plumbago spp.

Plumbaginaceae

The genus Plumbago belonging to the family Plumbaginaceae is a popular and medicinally very important group of medicinal plants. Three species, namely P. rosea, P. zeylanica and P. auriculata have been identified. Among these P. rosea and P. zeylanica are important ones.

Plumbago, in general is an esteemed remedy for leucoderma and other skin diseases. The synonyms of fire like agnih, vahnih, etc. are attributed to this drug to indicate the very burning action of the root, causing blisters on the skin (daranah). The drug is used only after adequate curing and purification. Root is the officinal part and it enters into the composition of preparations like Citrakasavam, Dasamularista, Gulgulutiktaka kasaya, Yogarajachurna, etc.

1. P. rosea Linn. syn. P. indica Linn.

Eng: Rosy-flowered Leadwort; San: Citrakah, Dhahanah;

Hin: Lalcitra, Raktacitra;

Ben: Lalchita;

Mal: Kotuveli, Chettikkoduveli, Chuvannakotuveli;

Tam: Chenkotuveli, Cittiramulam;

Kan: Kempacitramula;

Tel: Yerracitramulam

Rosy-flowered leadwort or Fire plant is a native of Coromandel Coast. It is found throughout India, in moist situations as well as cultivated. The roots are useful in dyspepsia, colic, inflammations, cough, bronchitis, helmenthiasis, haemorrhoids, elephantiasis, chronic and intermittent fever, leprosy, leucoderma, ringworm, scabies, hepatosplenomegaly, amenorrhoea, odontalgia, vitiated conditions of vata, kapha and anaemia. It is a pretty subscandent perennial shrub with semi -woody striate stems and flexible branches. Leaves are simple, alternate oblong, short cuneate at the base passing into a very short amplexicaul, exauriculate, and reddish petiole. Flowers are bright red, arranged in long terminal spikes. The calyx ribs are covered with stipitate, bifarious and subsessile gland. Corolla tube is slender and four times as long as the calyx. The stout roots are cylindrical, irregularly bent, light yellowish brown with smooth surface having short transverse shallow fissures at the regions of the bents. A light yellowish juice excudes from the cut surface. A healthy plant may produce 18-20 stout roots (Warrier et al, 1995).

The chemical constituents include plumbagin and sitosterol glucoside. Clinical trials have demonstrated that plumbagin oil from P. indica is useful in common wart (Satyavati et al, 1987). The roots are acrid, astringent, thermogenic, anthelmintic, constipating, expectorant, antiinflammmatory, abortifacient, alterant, anti-periodic, carminative, digestive, sudorific, narcotic, gastric, nervous stimulant and rejuvenating. Root is a powerful sialogogue and vesicant.

2. P. zeylanica Linn.

Eng:White flowered Leadwort; San:Chitraka;

Hin, Ben:Chitarak, Chitra; Mal:Vellakotuveli

Tam: Sittragam, Chittiramoolam;

Kan: Vahini; Mar: Chitraka;

Tel: Chitramulam

White flowered Leadwort or Chitarak is found wild in peninsular India and mostly in West Bengal. Root is used externally in leprosy and other skin diseases or obstinate character, aphthae, abscesses, influenza, piles and anasarca. Juice is used externally in scabies and ulcers. One of the important preparations of Chitrak is “Yograjguggal”, prescribed for arthritis, rheumatism, etc. The other well known preparations are “Chitrak Adivati” and “ Chitraka Haritaki”. In Unani system it is an ingredient of “Aqaruva-i- Kabir”, “Hab Ashkhar”, “Ma’jun Baladur”, “Ma’jun Raig Mahi”, etc. It is a branched undershrub. Roots are long and tuberous. Stem is striate. Leaves are simple, alternate, short petioled, ovate or ovate-oblong, acute with entire or wavy margin, 7x3.8cm and glabrous. Flowers are white, arranged in terminal spikes. Calyx is tubular, glandular-hairy. Corolla tube is slender; limb rotate and 5 lobbed. Stamens are 5 on a disc. Style is slender with 5 stigmatic branches. Fruit is membranous capsule enclosed within the persistent calyx.

The roots of P. zeylanica have been exhaustively studied and naphthaquinones have been isolated, namely, plumbagin, 3-chlroplumbagin, droserone (Sidhu et al, 1971; Padhye et al, 1973), 3,3’-biplumbagin(Chitranone), zeylanone and iso-zeylanone and a coumarin, elliptinone (Sankaram et al, 1976, 1979). It also contains 1,2(3)-tetrahydro-3,3’-biplumbagin and plumbazeylanone. The leaf is antirheumatic. Root is appetiser, sudorific, relieves pain, vasicant, diuretic, caustic, antidiarrhoeal and expellent of phlegmatic tumours. Root is uterine stimulant. Root and fruits have antiimplantation activity. Plumbagin induces antiimplantation, has abortifacient and antiovulatory activity and causes selective testicular lesions in dogs. It is also a mitotic inhibitor. In lower concentration it behaves like a spindle, poison but in higher concentration it exhibits radiomimetic, nucleotoxic and cyclotoxic effects. It also has antibacterial, antifungal and anticoagulant activities and shows antagonism to amphetamine hyperactivity in mice.

3. P. auriculata Lam. syn. P. capensis

Eng: Blue flowered Leadwort;

Mal: Neelakotuveli

The blue flowered Leadwort is often grown in gardens throughout India (Moos, 1976; Chunekar, 1982; Sharma, 1983). It is a native of Cape Province in South Africa. It is a constituent of many Ayurvedic drugs (KAU, 1991). The plant is a subshrub growing to a height of 1-1.5m. Leaves are elliptic to obovate, 3-4 x 1.5-2cm. Inflorescence is a raceme of length 3-4cm. Corolla is blue to violet. Stamens are 5 in number. Flowers and fruits may be upto 12 in number (Matthew, 1995).

Agrotechnology: The plant is grown in tropical to subtropical ecosystems. Warm humid tropical climate is most suited. They come up well in almost all types of deep and well drained soils. It is propagated vegetatively by stem cuttings. Three stem cuttings of size 15cm long are planted in polybags of size 14x10cm. IAA and IBA treatments will improve rooting of cuttings. The land is to be ploughed well. About 4 tonnes of FYM are to be applied, mixed thoroughly and seed bed of size 50cm breadth, 1.5cm height and convenient length are to be prepared. On these beds pits are taken at a distance of 25cm and the rooted plants are transplanted from the polybags. Regular irrigation and weeding are to be carried out. In the second year with the onset of monsoon, seedbeds are again refreshed after adding about 4 tonnes of FYM. At the end of second year tubers are collected. Care should be taken to wear gloves, else the chemical plumbagin present in the roots will cause burning sensation. The collected tubers are washed, tied into bundles and marketed. Plumbago yields about 7-10t tubers/ha with good management (Prasad et al, 1997).... leadwort

Loss Of Blood

As a result of trauma. This is perhaps the simplest example of all, when, as a result of an accident involving a large artery, there is severe haemorrhage.

Menstruation. The regular monthly loss of blood which women sustain as a result of menstruation always puts a strain on the blood-forming organs. If this loss is excessive, then over a period of time it may lead to quite severe anaemia.

Childbirth. A considerable amount of blood is always lost at childbirth; if this is severe, or if the woman was anaemic during pregnancy, a severe degree of anaemia may develop.

Bleeding from the gastrointestinal tract. The best example here is anaemia due to ‘bleeding piles’ (see HAEMORRHOIDS). Such bleeding, even though slight, is a common cause of anaemia in both men and women if maintained over a long period of time. The haemorrhage may be more acute and occur from a DUODENAL ULCER or gastric ulcer (see STOMACH, DISEASES OF), when it is known as haematemesis.

Certain blood diseases, such as PURPURA and HAEMOPHILIA, which are characterised by bleeding.... loss of blood

Madhuca Indica

J. F. Gmel.

Madhuca butyracea Macr.

Synonym: Aisandra butyracea (Roxb.) Baehni.

Family: Sapotaceae.

Habitat: Found in sub-Himalayan tract from Kumaon to Bhutan.

Ayurvedic: Madhuuka (related species).

Synonym: M. longifolia (Koen.) Macb. var. latifolia (Roxb.) Cheval. Bassia latifolia Roxb.

Family: Sapotaceae.

Habitat: A large tree, cultivated mainly in Uttar Pradesh, Bihar.

English: Mahua tree, Moha.

Ayurvedic: Madhuuka, Madhu- pushpa, Madhusrav, Gudapushpa.

Unani: Mahuaa.

Siddha/Tamil: Ieluppai.

Action: Flowers—stimulant, demulcent, laxative, anthelmintic, bechic. Seed oil—galactogenic, anticephalgic, emetic. Used in pneumonia, skin diseases, piles. Bark—astringent, emollient. Used for tonsilitis, gum troubles, diabetes, ulcers. Bark, seed oil and gum— antirheumatic.

The Ayurvedic Pharmacopoeia of India recommends the flower without stalk or calyx in asthma and pthisis.

The fruit pulp yielded a number of triterpenoids (including alpha- and beta-amyrin acetate); also n-hexaco- sanol, beta-D-glucoside of beta-sitos- terol and free sitosterol.

Nut shell gave beta-sitosterol gluco- side, quercetin and dihydroquercetin.

The carollas are rich source of sugars, vitamins, phosphorus, calcium and iron; magnesium and copper are also present. The sugars identified are sucrose, maltose, glucose, fructose, ara- binose and rhamnose.

The seeds yielded saponins—2,3- di-O-glucopyranoside of bassic acid (saponin A and saponin B). Mixture of saponins from seeds exhibits spermi- cidal activity.

Trunkbarkcontainedlupeol acetate, beta-amyrin acetate, alpha-spinasterol, erythrodiol monocaprylate, betulinic acid and oleanolic acid caprylates.

Dosage: Flower—10-15 g (API, Vol. II.); flower-juice—10-20 ml; bark— 50-100 ml decoction. (CCRAS.)... madhuca indica

Maerua Arenaria

Hook. f. & Thoms.

Synonym: M. oblongifolia (Forsk.) A. Rich.

Family: Capparidaceae.

Habitat: Punjab, Sind, Gujarat, Central and Southern India.

Ayurvedic: Morata, Piluparni, Madhusravaa.

Siddha/Tamil: Bhumichakkarai.

Folk: Murhari.

Action: Root—used for bleeding piles, as alterative in fevers; as a tonic in muscular debility.

(The root resembles liquorice root in appearance and taste.)... maerua arenaria

Merremia Tridentata

(Linn.) Hallier. f.

Synonym: Convolvulus tridentatus Linn.

Ipomoea tridentata (L.) Roth.

Family: Convolvulaceae.

Habitat: Upper Gangetic Plain, Bihar, Orissa, West Bengal, South India and Gujarat.

Ayurvedic: Prasaarini (Kerala and Karnataka), Tala-nili.

Siddha/Tamil: Mudiyaakunthal.

Action: Laxative, astringent, anti-inflammatory. Used in piles, swellings, rheumatic affections, stiffness of the joints, hemiplegia and urinary affections.

The aerial parts contain the flavo- noids, diometin, luteolin and their 7- O-beta-D-glucosides.... merremia tridentata

Mesua

Mesua nagassarium

Clusiaceae

San: Nagapuspah, Nagakesarah;

Hin: Nagakesar;

Ben: Nagkesar, Nagesar;

Mal: Nagappuvu,

Nagachempakam, Nanku, Vayanavu, Churuli, Eliponku;

Tam: Nagappu, Nanku;

Kan: Nagasampige;

Tel: Nagakesaramu, Gajapuspam; Mar,

Guj: Nagchampa

Importance: Mesua or Ironwood tree, commonly known as Nagapushpam is an important medicinal plant which finds varied uses in Ayurveda, Siddha and Unani. Leaves are used in the form of poultice which is applied to head in severe colds. Bark and roots in decoction or infusion or tincture is a better tonic and are useful in gastritis and bronchitis. Fixed oil expressed from seeds is used as an application for cutaneous affections, sores, scabies, wounds, etc. and as an embrocation in rheumatism. Dried flowers powdered and mixed with ghee, or a paste made of flowers with addition of butter and sugar, are given in bleeding piles as well as dysentery with mucus. They are also useful in thirst, irritability of the stomach, excessive perspiration, cough with much expectoration, dyspepsia, etc. Leaves and flowers are used in scorpion stings. Syrup of the flower buds is given for the cure of dysentery (Nadkarni et al, 1976). In Ayurveda, it is an ingredient of “Nagakeshara-adi-Churna”, used for bacillary dysentery and in “Naga Keshara Yoga”, for piles. In Unani system, the drug is an ingredient of large number of recipes like, “Jawarish Shehryaran” a stomach and liver tonic, “Hab Pachaluna”, an appetiser, “Halwa-i-supari pack” a general tonic, etc. (Thakur et al, 1989).

Distribution: The plant occurs in sub-tropical to tropical areas of East India, Andaman Islands and Western Ghats, upto an altitude of 1500m.

Botany: Mesua nagassarium (Burm.f.) Kosterm. syn. M. ferrea auct. non Linn. belongs to the family Clusiaceae. It is a medium sized to large evergreen tree, 18-30m in height and with reddish brown bark which peels off in thin flakes. Leaves are simple, opposite, thick, lanceolate, coriaceous, covered with waxy bloom underneath, and red when young, acute or acuminate and with inconspicuous nerves. Flowers are white, very fragrant, axillary or terminal, solitary or in pairs. Stamens are numerous, golden yellow, much shorter than the petals. Fruits are ovoid with a conical point surrounded by the enlarged sepals. Seeds are 1-4 in number, angular, dark brown and smooth (Warrier et al, 1995).

The flowers of Ochrocarpus longifolius are also sometimes referred to as Nagakesara. This tree is found in the West Coast of India (Thakur et al, 1989).

Agrotechnology: The plant prefers plains, riverbanks or places which do not experiences moisture stress for its luxuriant growth. Silty loam soil is suitable for its cultivation. The plant is propagated by seeds. Seed formation occurs in November-March. Seeds are to be collected and sown in seedbeds or polybags. 3-4 months old seedlings are used for transplanting. Pits of size 45cm cube are to be taken at a distance of 3-3.5m and filled with a mixture of 10kg FYM, sand and top soil and made into a mound. Seedlings are to be transplanted into small handpits taken on these mounds. FYM is to be applied twice a year. Regular irrigation and weeding are to be done. The tree flowers in the fourth year. Flowers can be collected, dried in the sun and marketed (Prasad et al,1997).

Properties and activity: Seed oil gives 4-phenyl coumarin analogues-mesuol, mammeigin, mesuagin, mammeisin and mesuone. Bark gives ferruols A and B. Heartwood gives xanthones- euxanthone, mesuaxanthones A and B and a tetroxygenated xanthone named ferraxanthone. Stamens give and -amyrin, -sitosterol, biflavonoids- mesuaferrones A and B, and mesuanic acid. Bark yields a lupeol-type triterpenoid also named guttiferol. Seed oil is rich in oleic, stearic and palmitic acids. Linoleic, arachidic and linolenic acids are also present.

Mesuaxanthones A and B and euxanthone are antiinflammatory, CNS depressant and antimicrobial. The essential oil from the stamens is antibacterial, antifungal, anthelmintic and that from fruit is antifungal. Oral administration of a compound preparation containing Mesua ferrea (flowers), Foeniculum vulgare (seeds), Curcuma zeodaria (tubers), Nigella sativa (seeds), Terminalia chebula (seeds) and T. arjuna (stem-bark) exhibited antiimplantation activity in rats. An Ayurvedic preparations containing M. ferrea has haemostatic and astringent properties and is particularly useful in uterine bleeding. Aerial part is CVS active, spasmolytic and diuretic. Phenol containing fraction of seed oil is antiasthmatic and antianaphylaxis. Bark is used as tonic after childbirth. Bark and unripe fruit is sudorific. Leaf and flower is an antidote for snakebite and scorpion sting. Flower bud is antidysenteric. Flower is stomachic and expectorant. Seed oil is antirheumatic. Unripe fruit and flower is astringent (Husain et al,1992).... mesua

Mesua Ferrea

Linn.

Synonym: M. nagassarium (Burm. f.) Kosterm.

Family: Guttiferae; Clusiaceae.

Habitat: Eastern Himalayas, Assam, West Bengal, Western Ghats, Travancore and the Andaman Islands.

English: Iron-wood, Mesu.

Ayurvedic: Naagakeshara, Naa- gapushpa, Chaampeya, Naaga, Naagakinjalika, Ahipushpa. (In Ayurvedic Formulary of India Part I, revised edn 2003, Keshara and Kesara are equated with Mesua ferrea, while Kumkuma is equated with Crocus sativus.)

Unani: Naarmushk.

Siddha/Tamil: Sirunagappo, Nagakesaram. Sirunagappo also consists of the tender fruits of Cinamonum wighti Meissn. Malabar Naagakeshar consists of the fruits of Dillenia pentagyna Roxb.

Action: Flower bud—antidysenteric. Flowers—astringent, haemostatic, anti-inflammatory, stomachic. Used in cough, bleeding piles, metrorrhagia. Essential oil from stamens—antibacterial, antifungal.

The Ayurvedic Pharmacopoeia of India recommends the use of dry stamens in gout, haemorrhagic disorders and diseases of the urinary bladder.

The heartwood gave xanthones— euxanthone, mesuaxanthones A and B, which exhibit anti-inflammatory, CNS depressant and antimicrobial activities.

Theseedoil gave4-phenylcoumarin analogues—mesuol, mammeigin, me- suagin, mammeisin and mesuone. Phenol-containing fraction of seed oil is antiasthmatic and antianaphylaxis.

Stamens gave alpha- and beta-amy- rin, beta-sitosterol, biflavonoids, me- suaferrones A and B, and mesuanic acid. Stamens constitute the drug Naa- gakeshar of Indian medicine, used as an astringent, haemostatic, particularly in uterine bleeding and renal diseases.

Ethanolic extract of the plant showed diuretic and hypotensive activity.

Dosage: Dried stamens—1-3 g powder. (API, Vol. II.)... mesua ferrea

Mimusops Elengi

Linn.

Family: Mimosaceae.

Habitat: Native to tropical America; naturalized in tropical and subtropical regions of India.

English: Sensitive-plant, Humble- Plant.

Ayurvedic: Lajjaalu, Laajavanti, Namaskaari, Samangaa, Sankochini, Shamipatraa, Khadirkaa, Raktapaadi.

Unani: Chhuimui, Sharmili, Laajwanti.

Siddha/Tamil: Thottalsurungi.

Action: Leaf—astringent, alterative, antiseptic, styptic, blood purifier. Used for diarrhoea, dysentery, haemophilic conditions, leuc- orrhoea, morbid conditions of vagina, piles, fistula, hydrocele and glandular swellings. Root—used in gravel and urinary complaints. A decoction is taken to relieve asthma.

The plant contains mimosine and turgorin. The periodic leaf movements exhibited by the plant are due to presence of derivatives of 4-O- (beta-D-glucopyranosyl-6'-sulphate)

Family: Sapotaceae.

Habitat: Cultivated in North India, Western Peninsula and South India.

English: Spanish-Cherry, West Indian Medlar, Bullet Wood.

Ayurvedic: Bakula, Keshara, Simhakeshara, Sthiraa, Sthira- pushpa, Vishaarada, Dhanvi, Madhupushpa, Madhugandha, Chirpushpa, Maulsiri.

Unani: Molsari.

Siddha: Magilam.

Action: Pulp of ripe fruit—astringent; used in chronic dysentery Flowers, fruit and bark—astringent. Bark—given for promoting fertility in women. Seeds—purgative. The leaves contain sterols, reducing sugars and tannins; roots, a steroidal saponin; stem bark, spinasterol and taraxerol; flowers, D-mannitol, beta-sitosterol and beta-sitosterol- D-glycoside; seeds, pentacyclic triterpene acids, mimusopic and mimusopsic acids.

Essential oil obtained from the plant is reported to be mycotoxic. Antimicrobial activity of the root extract has been reported. Saponins isolated from the seeds have been found to effect the cardiovascular activity in dogs and haemolytic activity in human beings. Spasmolytic activity in isolated ileum of guinea-pigs has also been recorded. Saponins from seeds also showed spermicidal activity.

Dosage: Seed, bark—10-20 g paste; 50-100 ml decoction. (CCRAS.)... mimusops elengi

Momordica Dioica

Roxb. Ex Willd.

Family: Cucurbitaceae.

Habitat: Throughout India, up to 1,500 m in the Himalaya.

English: Small Bitter Gourd, Bur Cucumber.

Ayurvedic: Karkotikaa, Karkotikaa- vandhyaa, Karkotaka, Karkota.

Siddha/Tamil: Tholoo-pavai, Paluppakai, Kaattupaagala.

Folk: Jangali Karelaa, Ban-Karelaa, Bhat-Karelaa, Dhar-Karelaa.

Action: Tuberous root—astringent, febrifuge, antiseptic, anthelmintic, spermicidal. Used in bleeding piles, urinary affections; smeared over body in high fever with delirium (as a sedative). A paste, prepared with the root of male plant, is applied externally for pain in the breast.

The root extract exhibited significant anti-allergic activity comparable with standard drugs used against allergy and bronchial asthma (in experimental animals).... momordica dioica

Moringa Pterygosperma

Gaertn.

Synonym: M. oleifera Lam.

Family: Moringaceae.

English: Drumstick, Horse-Radish.

Ayurvedic: Shigru (white var.), Madhu Shigru, Sigra, Shobhaan- jana, Haritashaaka. Raktaka, Murangi, Mochaka, Akshiva, Tikshnagandhaa.

Unani: Sahajan.

Siddha/Tamil: Murungai.

Action: All parts of the tree are reported to be used as cardiac and circulatory stimulant. Pods—antipyretic, anthelmintic; fried pods are used by diabetics. Flowers—cholagogue, stimulant, diuretic. Root juice—cardiac tonic, antiepileptic. Used for nervous debility, asthma, enlarged liver and spleen, deep-seated inflammation and as diuretic in calculus affection. Decoction is used as a gargle in hoarseness and sore throat. Root and fruit—antiparalytic. Leaf—juice is used in hiccough (emetic in high doses); cooked leaves are given in influenza and catarrhal affections. Root-bark—antiviral, anti-inflammatory, analgesic. Bark—antifungal, antibacterial. Stem-bark and flower—hypo- glycaemic. Seeds—an infusion, anti-inflammatory, antispasmodic and diuretic; given in venereal diseases.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicated the use of the dried root bark in goitre, glycosuria and lipid disorders (also dried seeds), and leaf, seed, root bark and stem bark in internal abscess, piles and fistula-in-ano.

The plant contains antibacterial principles, spirochin and pterygosper- min which are effective against both Gram-Positive and Gram-Negative bacteria.

The leaves contain nitrile glycosides, niazirin and niazirinin and mustard oil glycosides. The mustard oil glycosides showed hypotensive, bradycardiac effects and spasmolytic activity, justifying the use of leaves for gastrointestinal motility disorders.

The roots possess antibacterial, anti- choleric and antiviral properties due to the presence of pterygospermin, Spiro chin and benzylisothiocyanate. The root extract exhibited significant anti- inflammatory activity in carrageenan- induced paw-oedema in rats.

The leaves exhibited hypoglycaemic activity, although the plasma insulin level did not alter much.

The root and bark showed antifer- tility activity through biphasic action on the duration of the estrous cycle of female rats.

Dosage: Leaf—10-20 ml. juice. (API, Vol. III); root bark—2-5 g powder; stem bark—2-5 g powder; seed—5-10 g powder (API, Vol. IV). Leaf, flower, fruit, seed, bark, root— 1-3 g powder; 50-100 ml decoction. (CCRAS.)... moringa pterygosperma

Nelumbo Nucifera

Gaertn.

Nelumbium speciosum

Family: Nymphaeaceae.

Habitat: Throughout warmer parts of India, up to 1,800 m.

English: East Indian Lotus, Sacred Lotus.

Ayurvedic: Kamala, Padma, Nalina, Aravinda, Jalaja, Raajeeva, Pushkara, Ambuja, Abja, Pankaja. Pundarika (whitish), kokanada (red), Indivara (Bluish).

Unani: Used as a substitute for Nilofar.

Siddha/Tamil: Thaamarai, Ambel.

Action: Filament—astringent and haemostatic. Prescribed for bleeding piles and menorrhagia. Flowers—a decoction is given in cholera, fever, strangury, palpitation of heart. Rhizomes—given in piles, chronic dyspepsia and dysentery; applied externally to cutaneous eruptions, scabies and ringworm. Rhizome-arrowroot— given to children in diarrhoea and dysentery. Root—astringent, diuretic, antiemetic, cooling. Used for dysentery, dyspepsia, piles, skin affections and for its anticoagulant properties.

The Ayurvedic Pharmacopoeia ofIn- dia recommends dried rhizomes, with roots attached at nodes, in syncope and vertigo.

Flowers yielded quercetin, luteolin and their glycosides and kaempferol glycosides. Leaves gave quercetin, iso- quercitrin and leucoanthocyanidin.

Isoquinoline alkaloid, nuciferin, is neuroleptic. Active agents in the leaves are the alkaloids, nelumbin and roe- merin.

Dosage: Dried flower—12-24 g for decoction (API, Vol. II); rhizomes— 5-10 m powder; 10-20 ml juice (API, Vol. III). Seed—3-6 g powder; flower—10-20 ml juice. (CCRAS.)... nelumbo nucifera

Nyctanthes Arbor-tristis

Linn.

Family: Oleaceae; Nyctanthaceae.

Habitat: Outer Himalaya, Assam, West Bengal; cultivated in many parts of India.

English: Tree of Sorrow, Night Jasmine, Coral Jasmine.

Ayurvedic: Paarijaata, Shephaali, Shephaalikaa, Mandaara.

Unani: Harasingaar.

Siddha: Pavazha mattigai.

Action: Leaves—bitter tonic, chola- gogue, febrifuge, anti-inflammatory, antispasmodic, hypotensive, respiratory stimulant. Used for fevers, rheumatism, obstinate sciatica.

The leaves and seeds contain iri- doid glycosides; other constituents reported from the leaves are mannitol, beta-amyrin, beta-sitosterol, hentria- contane, benzoic acid, astragalin, nico- tiflorin, oleanolic acid, nyctanthic acid, friedelin and lupeol. The seeds contain a polysaccharide glucomannan.

All parts of the plant are used for allergic disorders. Alcoholic extract of the plant was found to inhibit passive cutaneous anaphylaxis (PCA) in experimental animals. The inhibition was comparable to standard drugs used for allergy and bronchial asthma.

Ethanolic extract of the leaves, flowers and seeds demonstrated strong stimulation of antigen specific and non-specific immunity in mice.

The 50% ethanolic extracts of the leaves, flowers, seeds and roots were found effective in treating caecal amoe- biasis caused by Entamoeba histolytica in rats. But the extracts did not exhibit direct amoebicidal activity in vitro against trophozoites of the parasite.

The iridoid glucosides showed an- tileishmanial activity both in vivo and in vitro.

Dosage: Leaf—10-20 ml juice. (CCRAS.)

Seeds—used in diabetes, also in cutaneous diseases. Filaments— astringent and cooling; prescribed for bleeding piles and menorrhagia. Plant—toxic on the nervous system.

The flowers contain flavonoids including quercetin, kaempferol, api- genin. Cardiac glucoside, nymphalin, showed sedative action in small doses.

The petroleum ether extract of the plant of Nymphaea species, given at a dose of 300 mg/kg i.p. prevented necrosis of the liver tissue and promoted, to some extent, liver regeneration in CCl4-induced toxicity.

Dosage: Dried flowers—3-6 g (API, Vol. III); seed—3-6 g. powder (CCRAS.).... nyctanthes arbor-tristis

Oxystelma Secamone

(Linn.) Karst.

Synonym: O. esculentum R. Br. Sarcostemma secamone (Linn.) Bennet.

Family: Asclepiadaceae.

Habitat: Throughout the plains and lower hills of India, including paddy fields and hedges rear semi-marshy places.

Ayurvedic: Dugdhikaa, Duudhila- taa, Duudhialataa .

Folk: Usipallai (Tamil Nadu); Dugdhani (Maharashtra); Jala- dudhi (Gujarat).

Action: Herb—antiseptic, depura- tive, galactogogue; decoction used as a gargle in stomatitis and sore throat. Latex—vulnerary. Fresh root—prescribed in jaundice.

A pregnane ester oligoglycoside (oxysine), a pregnane triglycoside (es- culentin), a cardenolide (oxyline), two more cardenolides, oxystelmoside and oxystelmine, have been isolated from the roots.

Dosage: Plant—10-20 ml juice; 50100 ml decoction. (CCRAS.)

Family: Rubiaceae.

Habitat: Central and Eastern Himlayas extending to Assam, West Bengal, Bihar, Orissa.

Ayurvedic: Talanili, Gand- haprasaarini. (Prasaarini is also equated with Raaja-balaa, Sida veronicaefolia.).

Siddha/Tamil: Talanili, Mudiyar Kundal.

Folk: Gandhabhaaduli (Bengali).

Action: Leaf—carminative, antiinflammatory, astringent, spasmolytic, antidiarrhoeal, diuretic, an- tilithic. Root— anti-inflammatory. Used for rheumatic affections, piles, inflammations of the liver, spleen and chest.

Aerial parts contain epi-friedelanol, embelin and beta-sitosterol. Leaves and stems gave iridoid glycosides, si- tosterol, stigmasterol, campesterol, ur- solic acid, hentriacontane, hentriacon- tanol, ceryl alcohol, palmitic acid and methyl mercaptan. The foetid smell is due to methyl mercaptan.

All parts of the plant have been employed for rheumatic affections.

A related species, Paederia scandens (Lour.) Merill, synonym P. tomentosa Blume, is known as Gandha Prasaarini. The iridoid glucosides, paedero- side, paederosidic acid and scandosides have been isolated from the plant.... oxystelma secamone

Pavetta Indica

Linn.

P. tomentosa Roxb. ex

Family: Rubiaceae.

Habitat: Throughout greater part of India, ascending to an altitude of about 1,500 m in the Himalayas, also recorded from the Andamans.

English: White-Pavetta.

Ayurvedic: Papata, Kathachampaa.

Siddha/Tamil: Pavattai.

Folk: Paapadi (Maharashtra).

Action: Root—bitter and aperient. Prescribed in visceral obstructions, renal dropsy and ascites. Leaves— used for fomenting piles and for haemorrhoidal pains. The root bark contains d-mannitol.... pavetta indica

Pilewort

Ranunculus ficaria. N.O. Ranunculaceae.

Synonym: Lesser Celandine, Little Celandine (not to be confused with Chelidonium majus , q.v.).

Habitat: Moist places, both open and shady.

Features ? Flower stem grows up to six inches (slightly longer than leaf stalk) with two or three leaves, and ending in a single bright yellow, buttercup-like flower, of usually eight petals and three sepals. Numerous leaves from the root on long stalks, glossy, heart-shaped, whitish-green blotches, notched margins. Root characteristically bunched into white, fleshy, club-shaped or oblong-rounded knots.

Part used ? Herb.

Action: Astringent.

Used almost entirely (as the common name denotes) in the treatment of piles. The ounce to pint boiling water infusion is taken consistently in wineglass doses, and an ointment is made by macerating the herb in boiling lard for twenty-four hours. Probably the best of all known remedies for this complaint, the combination with Witch Hazel is found to be particularly effective.... pilewort

Plantago Major

Linn.

Family: Plantaginaceae.

Habitat: The temperate and alpine Himalayas from Kashmir to Bhutan at altitudes of 600-3,500 m.

English: Broadleaf Plantain.

Ayurvedic: Ashvagola (var.).

Folk: Isabgol.

Action: Plant—haemostatic, antihistaminic, antibacterial, wound-healing in burns and inflammation of tissues. Leaves— cooling, astringent, diuretic, vulnerary, febrifuge. Used for diarrhoea, bacillary dysentery, hepatitis, urinary diseases, piles, ulcers and skin diseases. Leaves are used for cystitis with blood, haematuria and other bladder disorders.

The aqueous extract of the leaves showed anti-inflammatory activity in mice.

The aerial parts contain an iridoid glucoside, majoroside. The leaves contain a phenylpropanoid glycoside, plantamajoside, exhibiting antibacterial activity against several pathogenic bacteria including E. coli and Staphy- lococcus aureus. (The glycoside is less inhibitory than the free acids, caffeic, ferulic, and rosmarinic and esculetin.)... plantago major

Plantain

Plantago major. N.O. Plantaginaceae.

Synonym: Also called Ripple Grass and Way bread, the herb is known in Scotland as "Soldiers," and in America and New Zealand as "Englishman's Foot"—Plantain being supposed always to follow in his footsteps.

Habitat: Spreads in meadows, along the borders of fields, and in the hedgerows.

Features ? Springing from the root, the large leaves are ovate, blunt, and contract abruptly at the base. When, however, the plant is found in open fields the leaves tend to grow upwards on channelled stalks. The very small, brownish-purple flowers grow close together on a spike about five inches long. The plant is astringent to the taste, and odourless.

Part used ? The leaves are used medicinally.

Action: Alterative and diuretic.

Combined with other agents, they are of some value in piles and diarrhea. The fresh juice will give relief from insect and nettle stings.

John Skelton writes that Plantain "makes one of the best ointments for piles I know of."... plantain

Plumbago Zeylanica

Linn.

Family: Plumbaginaceae.

Habitat: Cultivated in gardens throughout India; also found wild in Peninsular India.

English: Ceylon Leadwort, Leadwort.

Ayurvedic: Chitraka, Agni, Vahni, Jvalanaakhya, Krshaanu, Hutaasha, Dahana, Sikhi.

Unani: Sheetraj Hindi. Siddha/Tamil: Chittramoolam.

Action: Root—intestinal flora normalizer, stimulates digestive processes; used for dyspepsia. Root paste is applied in order to open abscesses; a paste prepared with milk, vinegar or salt and water, is used externally in leprosy and other obstinate skin diseases. A cold infusion is used for influenza and black-water fever.

Key application: In sprue, malabsorption syndrome, piles and inflammatory diseases of ano-rectum. (The Ayurvedic Pharmacopoeia of India.)

The root yielded naphthoquinone derivatives, plumbagin being the most important active principle.

The root extract, after processing for plumbagin enhancement, has been used in a number of drug formulations for liver ailments. Experimentally, plumbagin prevented the accumulation of triglycerides in liver and aorta and regressed atheromatous plaques and abdominal aorta. The chloroform extract of the root showed significant activity against pencillin-resistant (also non-pencillin resistant) strains of Neisseria gonorrhoea. (The root is used for treating sexually transmitted diseases in traditional Indian medicine.)

In Siddha medicine, in Tamil Nadu, the plant is an ingredient in a number of drug formulations for treating cancers of the uterus, breast, lungs and oral cavity, in addition to haemorrhoids.

Plumbagin is abortifacient, antiovu- latory; causes selective testicular lesions in dogs; in lower doses it behaves like a spindle poison, in higher concentration exhibits radiomimetic nu- cleotoxic and cytotoxic effects.

Dosage: Detoxified root—1-2 g powder. (API, Vol. I.)... plumbago zeylanica

Polygonatum Multiflorum

All.

Family: Liliaceae.

Habitat: Western Himalayas from Kashmir to Kumaon and in Manipur.

English: Solomon's Seal.

Ayurvedic: Mahaa-medaa, Medaa (var.). (Substitute: Asparagus racemosus.)

Action: Anti-inflammatory, nervine, astringent. Used as an infusion for pulmonary complaints; as a poultice for piles and bruises.

The root and herb gave diosgenin and its glycosides.

Dosage: Root—3-5 g powder. (CCRAS.)... polygonatum multiflorum

Polygonum Aviculare

Linn.

Family: Polygonaceae.

Habitat: From Kashmir to Kumaon.

English: Knotgrass, Knotweed, Mexican Sanguinaria.

Folk: Machoti, Kesri.

Action: Astringent and haemostatic. Used for excessive menstruation, bleeding piles; bleeding from bowel, stomach, lungs, nose, throat; mucous colitis, children's summer diarrhoea.

Key application: In mild catarrhs of the respiratory tract, inflammatory changes to the oral and pharyngeal mucosa. (German Commission E.)

The plant gave flavonoids including quercetin, avicularin, quercitrin, and derivatives of kaempferol, esculetin and scopoletin. The plant also gave gallic, caffeic, oxalic., silicic, chloro- genic and p-coumaric acids; tannins including catechin.

The methanolic extract of the plant showed high protection against CCl4- induced hepatotoxicity in mice. This activity is attributed to the presence of flavonoid glucosides.

The flavonoids exhibit astringent properties and are found to decrease capillary fragility and have a cortisonelike-effect on gingival tissue. (J Ethno- pharmacol, 74(1), 2001.)... polygonum aviculare

Pongamia Pinnata

Pierre.

Synonym: P. glabra Vent. Derris indica (Lam.) Benett.

Family: Papilionaceae; Fabaceae.

Habitat: Western Ghats, tidal forests up to 1,200 m.

English: Pongam Oil tree, Indian Beech.

Ayurvedic: Karanja.

Siddha/Tamil: Pungam.

Action: Oil—applied in scabies, herpes, leucoderma and other cutaneous diseases; over chest in pneumonia and cold; also used internally as cholagogue in sluggish liver. Leaves—juice is prescribed in flatulence, dyspepsia, diarrhoea and cough. An infusion is given for leprosy and gonorrhoea. Root— a paste is used in scrofulous enlargements; juice is used for cleaning foul ulcers and closing fistulous sores. Stem bark—given internally in bleeding piles. Rind of pod and seed—prescribed in bronchitis and whooping cough. Leaf and seed—antileprotic. Leaf and seed oil—antirheumatic.

The tree is rich in flavonoids and related compounds. These include simple flavones, furanoflavonoids, chro- menoflavones, chromenochalcones, coumarones, flavone glucosides, sterols, triterpenes and a modified phenyl- alanine dipeptide. Seeds and seed oil gave karanjin, pongamol, pongapin and kanjone.

The aqueous extract of stem bark shows significant sedative and antipyretic effects in rats, and antispas- modic effect in vitro on smooth muscles.

In Indonesia, a decoction ofthe bark is drunk after child birth.

The aqueous extract of seeds showed significant antiviral activity against herpes simplex viruses HSV-1 and 2 cell lines experimentally. Albino rats, treated with the aqueous extract of seeds, recovered faster from induced infection and skin-burn than the untreated ones.

Dosage: Seed—250 mg powder; 510 g for decoction. (API, Vol. I.)... pongamia pinnata

Portulaca Tuberosa

Roxb.

Synonym: P. pilosa Linn.

Family: Portulacaceae.

Habitat: Peninsular India, near sea-coasts.

Ayurvedic: Bichhuu-buuti.

Folk: Jangali Gaajar (Gujarat), Sanjivani (Bihar).

Action: Leaves—an infusion is given internally in dysuria; externally applied to erysipelas. The herb shows diuretic, calculolythic, analgesic and antipyretic properties.

The aerial parts contain diterpe- noids, pilosanone A and B. leucorrhoea, dysmenorrhoea, arthritis, cramps, kidney stones, bleeding piles; as a mouth wash in pyrrhoea, gingivitis and sore throat.

Key application: In mild dismenor- rhoeal disorders; as a support for treatment of milder, nonspecific, acute diarrhoea and in light inflammation of the oral and pharyngeal mucosa. (German Commission E.)

The plant gave anthocyanins—cy- anidin and delphinidin. Aerial parts gave tannins (2-10%). The plant also gave choline, betaine, histidine, an essential oil and vitamin E.

The maximum amounts of tannins occur in the root stock (up to 17.5% on dry basis). The ethanolic and aqueous extract of the herb (1 : 5) contain 0.3 to 0.8% of tannin. The tannin fraction exhibited anti-mutagenic effect.

Potentilla fruticosa HK. (temperate Himalaya) is also used like Silverweed.

The flowers and young shoots contain flavonoids, quercetin, terniflorin, tribuloside and (-)-catechin. The plant also contains stigmasterol, beta-sitos- terol and campesterol; (-)-epicatechol gallate, (±)-catechol, (-)-epicatechol, (-)-epigallocatechol and (-)-epigallo- catechol gallate have been isolated from aerial parts.... portulaca tuberosa

Pomegranate

Punica granatum

Punicaceae

San: Dadimah;

Hin: Anar, Dhalim;

Ben: Dalim;

Tam: Madalai, Madalam;

Mal: Urumampazham, Matalam, Talimatala m, Matalanarakam; Kan :Dalimbe;

Tel: Dadima; Mar: Dalimba;

Guj: Dadam; Ass: Dalin

Importance: Pomegranate has long been esteemed as food and medicine and as a diet in convalescence after diarrhoea. The rind of the fruit is highly effective in chronic diarrhoea and dysentery, dyspepsia, colitis, piles and uterine disorders. The powdered drug boiled with buttermilk is an efficacious reme dy for infantile diarrohoea. The root and stem bark are good for tapeworm and for strengthening the gums. The flowers are useful in vomiting, vitiated conditions of pitta, ophthalmodynia, ulcers, pharyngodynia and hydrocele. An extract of the flowers is very specific for epistaxis. The fruits are useful in anaemia, hyperdipsia, pharyngodynia, ophthalmodynia, pectoral diseases, splenopathy, bronchitis and otalgia. The fruit rind is good for dysentery, diarrhoea and gastralgia. Seeds are good for scabies, hepatopathy and splenopathy. The important preparations using the drug are Dadimadighrtam, Dadimastaka churnam, Hinguvacadi churnam, Hingvadi gulika, etc (Sivarajan et al, 1994, Warrier et al, 1995).

Distribution: Pomegranate is a native of Iran, Afghanistan and Baluchistan. It is found growing wild in the warm valleys and outer hills of the Himalaya between 900m and 1800m altitude. It is cultivated throughout India, the largest area being in Maharastra.

Botany: Punica granatum Linn. belongs to the family Punicaceace. It is a large deciduous shrub up to 10m in height with smooth dark grey bark and often spinescent branchlets. Leaves are opposite, glabrous, minutely pellucid-punctuate, shining above and bright green beneath. Flowers are scarlet red or sometime yellow, mostly solitary, sometimes 2-4 held together. Stamens are numerous and inserted on the calyx below the petals at various levels. Fruits are globose, crowned by the persistent calyx. Rind is coriaceous and woody, interior septate with membraneous walls containing numerous seeds. Seeds are angular with red, pink or whitish, fleshy testa (Warrier et al, 1995).

Agrotechnology: Pomegranate is of deciduous nature in areas where winters are cold, but on the plains it is evergreen. A hot dry summer aids in the production of best fruits. Plants are grown from seeds as well as cuttings. Mature wood pieces cut into lengths of about 30cm are planted for rooting. The rooted plants are planted 4.5-6m apart. When planted close, they form a hedge which also yields fruits. Normal cultivation and irrigation practices are satisfactory for the pomegranate. An application of 30-45kg of FYM annually to each tree helps to produce superior quality fruits. The pomegranate may be trained as a tree with a single stem for 30-45cm or as a bush with 3 or 4 main stems. In either case suckers arising from the roots and similar growths from the trunk and main branches are removed once a year. Shortening of long slender branches and occasional thinning of branches should be done. The fruit has a tough rind and hence transportation loss is minimum (ICAR, 1966).

Properties and activity: Pomegranate fruit rind gives an ellagitannin named granatin B, punicalagin, punicalin and ellagic acid. Bark contains the alkaloids such as iso-pelletierine, pseudopelletierine, methyl isopelletierine, methyl pelletierine, pelletierine as well as iso-quercetin, friedelin, D- mannitol and estrone. Flowers give pelargonidin-3, 5-diglucoside apart from sitosterol, ursolic acid, maslinic acid, asiatic acid, sitosterol- -D-glucoside and gallic acid. Seeds give malvidin pentose glycoside. Rind gives pentose glycosides of malvidin and pentunidin. Fluoride, calcium, magnesium, vitamin C and phosphate are also reported from fruits. Leaves give elligatannins-granatins A and B and punicafolin.

Rind of fruit is astringent, fruit is laxative. Bark of stem and root is anthelmintic, and febrifuge. Rind of fruit and bark of stem and root is antidiarrhoeal. Pericarp possesses antifertility effect. Fixed oil from seeds are antibacterial. Bark, fruit pulp, flower and leaf are antifungal. Aerial part is CNS depressant, diuretic and hypothermic. The flower buds of pomegranate in combination with other plants showed excellent response to the patients of Giardiasis (Mayer et al, 1977; Singhal et al, 1983).... pomegranate

Pterospermum Acerifolium

Willd.

Family: Sterculiaceae.

Habitat: Maharashtra, Manipur, North Bengal, Bihar and Assam, Western Ghats and Andaman Islands.

English: Hathipaila.

Ayurvedic: Muchukun- da, Muchakunda, Kshatra- vriksha, Chivuka, Prativishnuka, Muchukunda Champaa. Karnikaara (also equated with Cassia fistula).

Unani: Gul-e-Muchkun.

Siddha/Tamil: Vennangu.

Action: Flower—anti-inflammatory, styptic (used for bleeding piles, haematuria, ulcers). Charred flowers and bark, mixed with the powder of Mallotus philippinensis, are applied to smallpox eruptions.

The fresh flowers yielded kaempfe- rol- 3 - O -beta - D -galactoside, along with luteolin and its 7-O-glucoside. The leaves also contain betulin, lu- peol, bauerenol, friedelin and beta- sitosterol.

Dosage: Flower—3-6 g powder. (CCRAS.)... pterospermum acerifolium

Raphanus Sativus

Linn.

Family: Cruciferae; Brassicaceae.

Habitat: Cultivated in Uttar Pradesh, Punjab, Maharashtra and Gujarat.

English: Radish.

Ayurvedic: Muulaka, Laghu- muulaka, Muulakapotikaa, Visra, Shaaleya, Marusambhava. Pods— Sungraa, Singri, Mungraa.

Unani: Muuli, Turb Fajal.

Siddha/Tamil: Mullangi.

Action: Radish—preparations are used in liver, gallbladder and urinary complaints. Green leaves— diuretic and carminative. Seeds— diuretic, purgative, expectorant.

A decoction of dry radish is given orally in piles. Extract of the dry root is given for hiccough, influenza, dysentery, colic and urinary troubles.

Key application: In peptic disorders, especially those related to dyskinesia of the bile ducts; and in catarrhs of the upper respiratory tract. (German Commission E.)

The Ayurvedic Pharmacopoeia of India recommends the juice of the whole plant in sinusitis; juice of the root in diseases of the throat and sinusitis; and the seed in amenorrhoea, cough and dyspnoea.

The fleshy root and seeds contain trans-4-methyl-thiobutenyl isothio- cyanate glucoside (the pungent principle), cyanidin-5-glucoside-3-sophoro- side, pelargonidin diglycoside, cyani- din diglycoside, 5-methyl-L-cysteine- sulphoxide (methiin), steroidal sa- pogenins and sulphorophene.

The enzymes present in the radish are phosphatase, catalase, sucrase, amylase, alcohol dehydrogenase and pyruvic carboxylase.

Radish contains caffeic acid and fer- ulic acid which exhibit hepatoprotec- tive and choleretic properties. It contains choline which prevents deposition of fat in liver. Amino acids, or- nithine, citrulline, arginine, glutamic acid and asparatic acid remove toxins from the body and urea acumulation.

Radish is a good source of ascorbic acid (15-40 mg/100 g), trace elements include aluminium, barium, lithium, manganese, silicon, titanium, also iodine (upto 18 mcg/100 g) and ascor- bigen.

Roots, leaves, flowers and pods are active against Gram-positive bacteria.

The seeds are reported to contain a broad spectrum antibiotic, machro- lysin, specific against Mycobacterium tuberculosis. Raphanin, extracted from the seeds, is active against Grampositive and Gram-negative bacteria.

A purified basic protein, homologous to nonspecific lipid transfer proteins, from seeds showed antifungal activity.

Raphanus caudatus Linn., synonym R. sativus var. caudatus, is known as Rat-Tail Radish.

A native to Java, it is cultivated in northern and western India. The root is not used; pods, purple or violet in colour, are consumed for properties attributed to Raphanus sp. These are known as Mungraa or Sungraa.

Dosage: Whole plant-20-40 ml juice; root—15-30 ml juice. (API, Vol. II.) Seed—1-3 g powder. (API, Vol. III.)... raphanus sativus

Ricinus Communis

Linn.

Family: Euphorbiaceae.

Habitat: Cultivated chiefly in Andhra Pradesh, Maharashtra, Karnataka, and Orissa.

English: Castor seed.

Ayurvedic: Eranda, Chitra- bija, Triputi; Tribija, Vaataari, Chanchu, Manda, Uruvaka, Gandharva-hastaa, Panchaan- gula, Vardhamaana, Uttaanpatraka, Vyaaghrapuchha, Chitraa.

Unani: Bedanjeer, Arand.

Siddha/Tamil: Ammanakku.

Action: Oil from seeds and young leaf—purgative. Oil is used in dermatosis and eczema. Leaves— used as poultice to extract the worm.

Root—a decoction is administered for lumbago and allied complaints.

Bark—purgative.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the decoction of the dried, mature root in rheumatism, pain in the urinary bladder, lumbago, diseases of the abdomen and inflammations; fresh leaf in helminthiasis, dysu- ria, arthritis, pain in the urinary bladder, dysuria, abscesses; dried seed powder in constipation, rheumatism, diseases of the liver and spleen, piles, lumbago, sciatica.

The root extract exhibited significant anti-inflammatory activity against carrageenan-, bradykinin-, 5-HT-and dextran-induced rat hind paw oedema. N-Demethylricinine showed dose-dependent anticholestatic and hepato- protective activities in rats.

Castor oil, derived from the seeds, is a well-known purgative (dose 520 ml).

Castor seed contains toxic components (2.8-3.0% on whole seed; about 10% in the flour) which are highly poisonous to human beings and animals. The principal toxic substance is the albumin, ricin. Allergens and a feebly toxic alkaloid ricinine is also present. An ulcerative factor in the seed is reported. Like other toxalbumins, ricin agglutinizes the mammalian red bleed corpuscles. (Ricin loses its toxicity and antigenic action on treatment with potassium permanganate.)

Castor oil consists principally of ri- cinoleic acid. Stearic, oleic, linoleic and dihydroxystearic acids are present in small amounts. The strong laxative property of castor oil is reported due to the local irritant action caused in the intestines by ricinoleic acid formed by hydrolysis under the influence of lipolytic enzymes. (The oil should not be used with fat-soluble vermifuge, it may increase its absorption and toxic- ity.)

Dosage: Root—20-30 g for decoction. (API, Vol. I.) Leaf—10- 20 ml juice; 2-5 g powder; seed— 0.5-3 g powder. (API, Vol. III.)... ricinus communis

Rectum, Diseases Of

The following are described under their separate dictionary entries: FAECES; HAEMORRHOIDS; FISTULA; DIARRHOEA; CONSTIPATION.

Imperforate anus, or absence of the anus, may occur in newly born children, and the condition is relieved by operation.

Itching at the anal opening is common and can be troublesome. It may be due to slight abrasions, to piles, to the presence of threadworms (see ENTEROBIASIS), and/or to anal sex. The anal area should be bathed once or twice a day; clothing should be loose and smooth. Local application of soothing preparations containing mild astringents (bismuth subgallate, zinc oxide and hamamelis) and CORTICOSTEROIDS may provide symptomatic relief. Proprietary preparations contain lubricants, VASOCONSTRICTORS and mild ANTISEPTICS.

Pain on defaecation is commonly caused by a small ulcer or ?ssure, or by an engorged haemorrhoid (pile). Haemorrhoids may also cause an aching pain in the rectum. (See also PROCTALGIA.)

Abscess in the cellular tissue at the side of the rectum – known from its position as an ischio-rectal abscess – is fairly common and may produce a ?stula. Treatment is by ANTIBIOTICS and, if necessary, surgery to drain the abscess.

Prolapse or protrusion of the rectum is sometimes found in children, usually between the ages of six months and two years. This is generally a temporary disorder. Straining at defaecation by adults can cause the lining of the rectum to protrude outside the anus, resulting in discomfort, discharge and bleeding. Treatment of the underlying constipation is essential as well as local symptomatic measures (see above). Haemorrhoids sometimes prolapse. If a return to normal bowel habits with the production of soft faeces fails to restore the rectum to normal, surgery to remove the haemorrhoids may be necessary. If prolapse of the rectum recurs, despite a return to normal bowel habits, surgery may be required to rectify it.

Tumours of small size situated on the skin near the opening of the bowel, and consisting of nodules, tags of skin, or cauli?ower-like excrescences, are common, and may give rise to pain, itching and watery discharges. These are easily removed if necessary. Polypi (see POLYPUS) occasionally develop within the rectum, and may give rise to no pain, although they may cause frequent discharges of blood. Like polypi elsewhere, they may often be removed by a minor operation. (See also POLYPOSIS.)

Cancer of the rectum and colon is the commonest malignancy in the gastrointestinal tract: around 17,000 people a year die from these conditions in the United Kingdom. Rectal cancer is more common in men than in women; colonic cancer is more common in women. Rectal cancer is a disease of later life, seldom affecting young people, and its appearance is generally insidious. The tumour begins commonly in the mucous membrane, its structure resembling that of the glands with which the membrane is furnished, and it quickly in?ltrates the other coats of the intestine and then invades neighbouring organs. Secondary growths in most cases occur soon in the lymphatic glands within the abdomen and in the liver. The symptoms appear gradually and consist of diarrhoea, alternating with attacks of constipation, and, later on, discharges of blood or blood-stained ?uid from the bowels, together with weight loss and weakness. A growth can be well advanced before it causes much disturbance. Treatment is surgical and usually this consists of removal of the whole of the rectum and the distal two-thirds of the sigmoid colon, and the establishment of a COLOSTOMY. Depending upon the extent of the tumour, approximately 50 per cent of the patients who have this operation are alive and well after ?ve years. In some cases in which the growth occurs in the upper part of the rectum, it is now possible to remove the growth and preserve the anus so that the patient is saved the discomfort of having a colostomy. RADIOTHERAPY and CHEMOTHERAPY may also be necessary.... rectum, diseases of

Rubia Cordifolia

Linn.

Synonym: R. munjesta Roxb.

Family: Rubiaceae.

Habitat: Throughout India, ascending to an altitude of 3,700 m.

English: Indian Madder, Bengal Madder.

Ayurvedic: Manjishthaa, Vikasaa, Samangaa, Yojanavalli, Kaalameshi- ka, Raktaangi, Raktayashtikaa, Arunaa, Gandira, Jingi.

Unani: Manjeeth.

Siddha/Tamil: Manjitti.

Action: Roots and dried stem— blood purifier, astringent, diuretic, emmenagogue, deobstruent, antidysenteric, antiseptic, alterative.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the use of the dried stem in blood, skin and urinogenital disorders; dysentery; piles, ulcers, inflammations; erysipelas, skin diseases and rheumatism. (Roots, leaves and seeds of R. cordifolia, R. tinctorum and allied species are used in amenorrhoea, liver diseases, gall and spleen complaints.) (Mutagenic and carcinogenic aspects of the drug are under investigation.)

It is reported that after oral administration of the root decoction, the urine and bones of the patient show a red tinge.

The roots are rich in anthraquinones and their glycosides (around 20), the important ones include purpurin (tri- hydroxy anthraquinone), munjistin (xanthopurpurin-2-carboxylic acid); besides xanthopurpurin, peudopur- purin (purpurin-3-carboxylic acid), free alizarin as well as its glucoside.

Whole plant yielded pentacylic tri- terpenic acids—rubicoumaric and ru- bifolic acids.

Antitumour cyclic hexapeptides have been isolated from the root (while lucidin is thought to be carcinogenic).

The root extracts of R. sikkimensis Kurz, known as Naaga-Madder (Nepal eastwards to Assam, Nagaland and Ma- nipur); are very similar to those of R. cordifolia.

Dosage: Stem—2-4 g. (API, Vol. III.)... rubia cordifolia

Rumex Crispus

Linn.

Family: Polygonaceae.

Habitat: Native to Europe; found in Mt. Abu.

English: Yellow Dock, Curled Dock.

Ayurvedic: Chukra, Chukrikaa, Patraamla, Rochani, Shatvedhani.

Action: Root—used as a laxative in rheumatism, bilious disorders, and as an astringent in piles and haemorrhagic affections; also used for skin eruptions, chronic skin diseases, scrofula, scurvy, congested liver and jaundice. Acts like Sarsaparilla when used for scrofulous skin affections and glandular swellings. Seeds— astringent. Used for dysentery.

The root contains anthraquinones (about 2.17-4%) including nepodin, and other glycosides based on chryso- phanol, physcion and emodin; also tannins, rumicin and oxalates. Large doses should be avoided. Disturbances caused by the plant are attributed to rumicin. The root and rhizome are reported to stimulate bile production. (Natural Medicines Comprehensive Database, 2007.)

The leaves contain 30 mg/100 g ascorbic acid.

R. crispus is pharmacologically more active than rhubarb, because the extracts of the roots of the former contain more quantity of anthraquinones (2.17%) than the extracts of the latter (1.42%).

It has been suggested that Amlavetas should be equated with R. crispus.... rumex crispus

Saccharum Munja

Roxb.

Synonym: S. sara Roxb. S. bengalense Retz. Erianthus munja Jesw.

Family: Gramineae; Poaceae.

Habitat: Throughout the plains and low hills of India.

Ayurvedic: Munja, Bhadramuja, Vaana, Shara, Sara, Raamshara.

Siddha/Tamil: Munjipul, Munjap- pullu.

Folk: Sarpata.

Action: Refrigerant. Useful in burning sensation, thirst, dyscrasia, erysipelas and urinary complaints.

The Ayurvedic Pharmacopoeia of India recommends the use of the root in dysuria, giddiness and vertigo.

The stem is a good source of furfural (yield 5.67%, dry basis). It yields 19.5% (on dry weight) of reducing sugars when digested with sulphuric acid; glucose, xylose, galactose and rhamnose have been identified in the hydrolysate which contains 34.5% fermentable sugars. (It can be used as a potential source of alcohol.)

In Kerala, Saccharum arundinaceum Retz. is used as Shara for dysuria, diseases due to vitiated blood, erysipelas, leucorrhoea and piles. The grass is known as Raamshara in North India. It can also be used for the production of furfural (yield 5.1% dry basis) and yields 24.1% of reducing sugars when digested with sulphuric acid. The hy- drolysate contains 65% of fermentable sugars, viz. glucose, xylose, galactose and rhamnose.

Dosage: Root—20-50 g for decoction; 6-10 g powder. (API, Vol. III.)... saccharum munja

Saccharum Spontaneum

Linn.

Family: Gramineae; Poaceae.

Habitat: Throughout India. English: Thatch Grass.

Ayurvedic: Kaasha, Kandekshu, Shvetachaamara.

Siddha/Tamil: Naanal, Pai Karumbu.

Action: Plant—cooling, astringent, diuretic, galactagogue. Used in the treatment of burning sensation, dysuria, dyscrasia, kidney and bladder stones, dysentery, bleeding piles. Root—diuretic, galactagogue.

Ayurvedic Pharmacopoeia of India recommends the root in calculus, dy- suria and haemorrhagic diseases.

Dosage: Root—3-6 g powder. (API, Vol. III.)

The Five-Grassroots (Tripanchmuu- la) of Ayurvedic medicine contain extracts of S. munja, S. officinarum and S. spontaneum. The compound is prescribed as a diuretic.... saccharum spontaneum

Salix Caprea

Linn.

Family: Salicaceae.

Habitat: Kashmir, Punjab, Himachal Pradesh and Uttar Pradesh.

English: Sallow, Goat Willow, Common Willow.

Ayurvedic: Vetasa, Vaanira, Vidula, Vanjula, Vaanjulaa. In Kerala Homonoia riparia Lour., Euphorbiaceae, is used as Vetasa or Jalavetasa.

Unani: Bed Mushk.

Action: Distilled water from flowers—cordial, stimulant; externally applied to headache. Stem and leaves—astringent. Leaves—decoction used as febrifuge. Bark and twigs—astringent, applied to piles. Ash of wood—used in haemoptysis; mixed with vinegar, applied to piles.

Alkaloids, glycosides and saponins of male racemes increase the amplitude and slow the heartbeat and act more rapidly than digitalis on isolated frog heart.

Flavonoids present in the male racemes are: diometin, isorhamnetin, cap- reoside and salicapreoside.

Phenol glycosides present in the bark are: delphinidin, cyanidin, pipe- colic acid, fragilin, picein, salicin, sal- icortin, salireproside, triandrin and vimalin. Tannin content is reported to be 8-13%.

Salix daphnoides Vill. and Salix ele- gans Wall. (The Himalayas from Kash mir to Nepal) are also known as Jalave- tasa.

Dosage: Leaf, bark, root—50- 100 ml decoction. (CCRAS.)... salix caprea

Salix Tetrasperma

Roxb.

Family: Salicaceae.

Habitat: Throughout the greater part of India, along the banks of rivers and streams.

English: Indian Willow.

Ayurvedic: Jalavetasa, Naadeya, Niketan, Baishi.

Siddha/Tamil: Attupalai.

Folk: Vaanira, Vaalunja.

Action: Dried leaves—antiinflammatory, given in rheumatism, swellings, piles. Bark—febrifuge.

The bark is reported to contain 6.5% tannin, also salicin A.... salix tetrasperma



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