Pilocarpus microphyllus Health Dictionary

Pilocarpus Microphyllus: From 1 Different Sources


Stapf.

Family: Rutaceae.

Habitat: Native to tropical America; cultivated in Indian gardens.

Family: Umbelliferae; Apiaceae.

Habitat: Native to the Mediterranean region; cultivated in Uttar Pradesh., Punjab, Assam and Orissa.

English: Anise, Aniseed.

Unani: Anisoon, Baadiyaan-roomi.

Action: Carminative, diuretic, anticholerin, antispasmodic, expectorant. Used for flatulence, dry coughs, whooping cough, bronchitis.

Key application: Internally in dyspeptic complaints; internally and externally in catarrhs of the respiratory tract. (German Commission E, ESCOP, WHO, The British Herbal Pharmacopoeia.)

The fruit gave volatile oil consisting mainly of trans-anethole (70-90%), with estragole, anise ketone, anisic acid, beta-caryophyllene, anisaldehyde, linalool. The fruit contained traces of furocoumarins; seeds gave benzoic acid, caffeic acid, containing protein and myristicin. Roots afforded sterols, coumarins and flavone glyco- sides. Aniseed has been demonstrated to increase the mucociliary transport in vitro and to significantly increase liver-regeneration in rats.

Aniseed is also used as a galacta- gogue. This property is thought due to the presence of polymers of anethole, dianethole and photoanethole.

Aqueous extract of roasted aniseed is reported to show cholinomimetic effect on rat blood pressure, rat jejunum and frog rectus abdominis preparations.

Alcoholic extract of aniseeds possesses antimicrobial and fungicidal activity.

Anethole has a structure similar to catecholamines including adrenaline, noradrenaline and dopamine and to the hallucinogenic compound myris- ticin as well. (Natural Medicines Comprehensive Database, 2007.)
Health Source: Indian Medicinal Plants
Author: Health Dictionary

Pilocarpine

A plant alkaloid and the primary bioactive substance reducible from Pilocarpus spp. (Jaborandi leaves). It is an almost pure parasympathomimetic (cholinergic), inducing lowered blood pressure and stimulating glandular secretions...EVERYWHERE. It stimulates sweating as well, a sympathetic cholinergic response. Anyway, it is used in eye drops these days to contract the pupil, lower ocular fluid pressure and take some of the stress off glaucoma. The refined alkaloid is better in the eyes, but the dried leaves are the usual complex agents of herb use and have some therapeutic values in low doses. Good Lobelia or Asclepias will work similarly and are both safer, fresher and more predictable as botanicals.... pilocarpine

Convolvulus Pluricaulis

Choisy.

Synonym: C. Microphyllus Sieb. C. Prostratus Forsk

Family: Convolvulaceae.

Habitat: Throughout India, Ascending To 2,000 M In The Himalayas.

Ayurvedic: Shankhapushpi, Shankhaahvaa, Kshirapushpi, Maangalya Kusuma (White- Flowered). Blue-Flowered Var., Vishnukraanti, Vishnukraantaa, Vishnugandhi Is Equated With Evolvulus Alsinoides Linn.

Unani: Sankhaahuli (Blue-Flowered)

Siddha/Tamil: Sivakraandi (White- Flowered), Vishnukraandi (Blue- Flowered).

Action: Plant—Brain Tonic, Tranquilizer Used In Nervine Disorders, Mental Aberration, Anxiety Neurosis, Internal Haemorrhages, Spermatorrhoea. Also Astringent, Antidysenteric, Antispasmodic, Antiphlogistic, Febrifuge, Alterative. Flowers—Styptic, Used For Uterine Bleeding. Leaf—Antiasthmatic, Used In Chronic Bronchitis. Root— Used In Gastric And Duodenal Ulcers, Uterine Affections And For Promoting Fertility.

The Ayurvedic Pharmacopoeia Of India Recommends The Plant For Epilepsy. The Plant Contains Sankhpushpine Alkaloids.

The Alcoholic (50%) Extract Of The Plant, When Administered To Rats (Through Gastric Intubation At Different Intervals), Has Shown Enhanced Neuropeptide Synthesis Of The Brain. It Induces An Increase In Brain Protein Content And Increases Acquisition Efficiency.

Evolvulus Alsinoides Contains Pen- Tatriacontane, Triacontane And Beta- Sitosterol.

Shankhapushpi Syrup (A Compound Containing C. Pluricaulis, Centella Asiatica, Nardostachys Jatamansi, Nepeta Hindostana, Nepeta Elliptica And Onos- Ma Bracteatum), When Administered With Phenytoin, A Modern Antiepilep- Tic Drug, Reduced Not Only Antiepileptic Activity Of Phenytoin But Also Lowered Plasma Phenytoin Levels.

Dosage: Whole Plant—3-6 G Powder. (Api Vol. III.)... convolvulus pluricaulis

Jaborandi

Pilocarpus jaborandi

FAMILY: Rutaceae

SYNONYMS: Pernambuco jaborandi, P. pennatifolius, iaborandi, jamborandi, arrudo do mato, arruda brava, jamguaraddi, juarandi.

GENERAL DESCRIPTION: A woody shrub up to 2 metres high with a smooth, greyish bark, large brownish-green leathery leaves containing big oil glands and reddish-purple flowers.

DISTRIBUTION: Native to Brazil; other species are found in Paraguay, Cuba, the West Indies and Central America.

OTHER SPECIES: There are many members of the Rutaceae and Piperaceae family known simply as jaborandi, such as Piper jaborandi. Others include maranham jaborandi (P. microphyllus), ceara jaborandi (P. trachylophus) and aracti jaborandi (P. spicatus).There is consequently some confusion about the exact botanical source of the oil.

HERBAL/FOLK TRADITION: Jaborandi induces salivation and most gland secretions; it was also used at one time to promote hair growth. ‘Useful in psoriasis, prurigo, deafness ... chronic catarrh, tonsillitis and particularly dropsy.’ .

ACTIONS: Antiseptic, diaphoretic, emmenagogue, galactagogue, stimulant (nerve).

EXTRACTION: Essential oil by steam distillation from the dried leaflets.

CHARACTERISTICS: An orange or yellow liquid with a sweet-herbaceous fruity odour.

PRINCIPAL CONSTITUENTS: Pilocarpine is the main active constituent; also isopilocarpine, pilocarpidine, methyl nonyl ketone, dipentene and other hydrocarbons.

SAFETY DATA: Oral toxin, skin irritant, abortifacient.

AROMATHERAPY/HOME: USE None.

OTHER USES: Various hypodermic solutions are prepared from pilocarpine: the crude oil is rarely used. Little used in perfumery or flavour work due to toxicity.... jaborandi




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