Polypharmacy Health Dictionary

Polypharmacy: From 4 Different Sources


The practice of prescribing several drugs to 1 person at the same time.
Health Source: BMA Medical Dictionary
Author: The British Medical Association
1 The administration of many drugs at the same time. 2 The administration of an excessive number of drugs.
Health Source: Community Health
Author: Health Dictionary
A term applied to the administration of too many drugs to one person. Sometimes combinations of drugs are an e?ective means of treatment, reducing the risk of drug resistance. Polypharmacy, however, worsens the risk of drug interactions and of adverse effects, especially in the elderly.
Health Source: Medical Dictionary
Author: Health Dictionary

Medicine Of Ageing

Diseases developing during a person’s lifetime may be the result of his or her lifestyle, environment, genetic factors and natural AGEING factors.

Lifestyle While this may change as people grow older – for instance, physical activity is commonly reduced – some lifestyle factors are unchanged: for example, cigarette smoking, commonly started in adolescence, may be continued as an adult, resulting in smoker’s cough and eventually chronic BRONCHITIS and EMPHYSEMA; widespread ATHEROSCLEROSIS causing heart attacks and STROKE; osteoporosis (see BONE, DISORDERS OF) producing bony fractures; and cancer affecting the lungs and bladder.

Genetic factors can cause sickle cell disease (see ANAEMIA), HUNTINGTON’S CHOREA and polycystic disease of the kidney.

Ageing process This is associated with the MENOPAUSE in women and, in both sexes, with a reduction in the body’s tissue elasticity and often a deterioration in mental and physical capabilities. When compared with illnesses described in much younger people, similar illnesses in old age present in an atypical manner

– for example, confusion and changed behaviour due to otherwise asymptomatic heart failure, causing a reduced supply of oxygen to the brain. Social adversity in old age may result from the combined effects of reduced body reserve, atypical presentation of illness, multiple disorders and POLYPHARMACY.

Age-related change in the presentation of illnesses This was ?rst recognised by the specialty of geriatric medicine (also called the medicine of ageing) which is concerned with the medical and social management of advanced age. The aim is to assess, treat and rehabilitate such patients. The number of institutional beds has been steadily cut, while availability of day-treatment centres and respite facilities has been boosted – although still inadequate to cope with the growing number of people over 65.

These developments, along with day social centres, provide relatives and carers with a break from the often demanding task of looking after the frail or ill elderly. As the proportion of elderly people in the population rises, along with the cost of hospital inpatient care, close cooperation between hospitals, COMMUNITY CARE services and primary care trusts (see under GENERAL PRACTITIONER (GP)) becomes increasingly important if senior citizens are not to suffer from the consequences of the tight operating budgets of the various medical and social agencies with responsibilities for the care of the elderly. Private or voluntary nursing and residential homes have expanded in the past 15 years and now care for many elderly people who previously would have been occupying NHS facilities. This trend has been accelerated by a tightening of the bene?t rules for funding such care. Local authorities are now responsible for assessing the needs of elderly people in the community and deciding whether they are eligible for ?nancial support (in full or in part) for nursing-home care.

With a substantial proportion of hospital inpatients in the United Kingdom being over 60, it is sometimes argued that all health professionals should be skilled in the care of the elderly; thus the need for doctors and nurses trained in the specialty of geriatrics is diminishing. Even so, as more people are reaching their 80s, there seems to be a reasonable case for training sta? in the type of care these individuals need and to facilitate research into illness at this stage of life.... medicine of ageing

Combinations, Formulae

 In the evolution of herbal medicine it was discovered that some remedies have affinities and assist others in therapeutic action. An older generation of herbalists learnt how to ‘blend’ herbs according to their properties. Although empiric, such intelligent observation over centuries has developed into lore handed down as traditional medicine.

Use of herbs in combination enhances activity of the mild ones and modifies effects of the strong. Volatile properties of one may be kept in balance by opposing alkaloids, glycosides, etc.

Present practice views with disfavour the combination of several remedies, approval being given to a maximum of no more than four plant substances.

Herbs may be combined in equal parts or in specific proportions; i.e. Elder 4, Ladies’ Mantle 3 and Pulsatilla 1: represent Elder 4 parts, Ladies’ Mantle 3 parts and Pulsatilla 1 part.

The object of combining medicines is (a) to augment, correct or modify the action of a remedy, (b) to obtain a joint operation of two or more remedies, (c) to obtain a new medicine and (d) to afford a suitable form for administration.

“A combination of similar remedies will produce a more certain, speedy and considerable effect than an equivalent dose of any single one.” (Fordyce) Some herbs used singly may be of little use, their true value lying in a correct combination. Referred to as polypharmacy where a number of remedies are used in one prescription. ... combinations, formulae




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