Potassium-channel Activators: From 1 Different Sources
Drugs that have the ability to dilate ARTERIES and VEINS and are used to relieve pain in ANGINA of the HEART. Nicorandil is the main example.
A metal which, on account of its great a?nity for other substances, is not found in a pure state in nature. Its salts are widely used in medicine but, as their action depends in general not on their metallic radical but upon the acid with which it is combined, their uses vary greatly and are described elsewhere. All salts of potassium depress the heart’s action as a result of action by the potassium ion.... potassium
A salt of the metallic element POTASSIUM. It is used as a skin antiseptic (see ANTISEPTICS) and for cleaning wounds; its astringent e?ect is useful in the treatment of DERMATITIS. It should not be taken internally because the compound is poisonous.... potassium permanganate
A substance used to relieve discomfort in mild urinary tract infections by making the urine less acid.... potassium citrate
an artificial sweetener (E950) 200 times sweeter than sugar. It is often used in combination with other sweeteners to produce a superior flavour. Not metabolized by the body, it is suitable for use in diabetic foods and can be used in cooking.... acesulfame potassium
(calcium antagonist) a drug that inhibits the influx of calcium ions into cardiac and smooth-muscle cells; it therefore reduces the strength of heart-muscle contraction, reduces conduction of impulses in the heart, and causes *vasodilatation. Calcium-channel blockers, which include *amlodipine, *diltiazem, *nicardipine, *nifedipine, and *verapamil, are used to treat angina and high blood pressure.... calcium-channel blocker
a protein that spans a cell membrane to form a water-filled pore through which ions (e.g. calcium [Ca2+], sodium [Na+], potassium [K+]) can pass into or out of the cell.... ion channel
enzymes that convert the inactive substance *plasminogen to the active enzyme *plasmin, which digests blood clots (see fibrinolysis). There are two types of plasminogen activators, *tissue-type plasminogen activator (tPA) and urokinase-like plasminogen activator (uPA). See blood coagulation.... plasminogen activators
any one of a class of drugs that enhance the movement of potassium ions through the *ion channels in cell membranes. In the case of smooth muscle cells, such as those in the walls of arteries, their sensitivity to the normal stimuli to contract is reduced. The result is relaxation of the muscle fibres and widening of the arteries. Potassium-channel activators are used for improving the blood supply to the heart muscle in angina pectoris. Possible side-effects include headache, flushing, vomiting, dizziness, and weakness. A currently available member of the class is nicorandil.... potassium-channel activator
a salt of potassium used to prevent and treat potassium deficiency, especially during treatment with digoxin or anti-arrhythmic drugs. Some irritation in the digestive system may occur. Severe potassium deficiency may be treated by intravenous infusion.... potassium chloride
see ion channel.... sodium channel
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