Proerythroblast Health Dictionary

Proerythroblast: From 1 Different Sources


n. the earliest recognizable precursor of the red blood cell (erythrocyte). It is found in the bone marrow and has a large nucleus and a cytoplasm that stains deep blue with *Romanowsky stains. See also erythroblast; erythropoiesis.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Erythropoeisis

The process by which ERYTHROCYTES or red blood cells are produced. The initiating cell is the haemopoietic stem cell from which an identi?able proerythroblast develops. This goes through several stages as a normoblast before losing its nucleus to become an erythrocyte. This process takes place in the blood-forming bone-marrow tissue.... erythropoeisis

Erythroblast

n. any of a series of nucleated cells (see normoblast; proerythroblast) that pass through a succession of stages of maturation to form red blood cells (*erythrocytes). Erythroblasts are normally present in the blood-forming tissue of the bone marrow, but they may appear in the circulation in a variety of diseases (see erythroblastosis). See also erythropoiesis.... erythroblast

Erythropoiesis

n. the process of red blood cell (*erythrocyte) production, which normally occurs in the blood-forming tissue of the *bone marrow. The ultimate precursor of the red cell is the *haemopoietic stem cell, but the earliest precursor that can be identified microscopically is the *proerythroblast. This divides and passes through a series of stages of maturation termed respectively early, intermediate, and late *normoblasts, the latter finally losing its nucleus to become a mature red cell. See also haemopoiesis.... erythropoiesis



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