Proton Pump: From 2 Different Sources
A key enzyme system in the parietal cells of the mucosal lining of the stomach: hydrogen ions are produced which acidify the stomach’s secretions and convert pepsinogen to PEPSIN, an active participant in the digestion of food.
the enzyme system in the *parietal cells of the stomach that stimulates acid secretion into the stomach by exchanging hydrogen ions for potassium ions. See proton-pump inhibitor.
These are drugs that inhibit the production of acid in the stomach by blocking a key enzyme system, known as the PROTON PUMP, of the parietal cells of the stomach. The drugs include omeprazole, lansoprazole and pantoprazole, and they are the treatment of choice for oesophagitis (erosion and stricture – see under OESOPHAGUS, DISEASES OF); for the short-term treatment for gastric ulcer (see under STOMACH, DISEASES OF) and DUODENAL ULCER; and, in combination with ANTIBIOTICS, for the eradication of Helicobacter pylori.... proton-pump inhibitors
See HEART, ARTIFICIAL.... cardiac pump
The contraction and relaxation of the limb muscles that helps pump the low pressure venous blood from the extremities back to the central collecting system.... muscle pump
A device used to draw milk from the breasts in order to relieve overfull breasts during lactation, to express milk for future use, or to feed a baby who is unable to suckle.... breast pump
A machine that is used for the administration of a continuous, controlled amount of a drug or other fluid. The fluid is delivered through a needle that is inserted into a vein or under the skin.... pump, infusion
See lavage, gastric.... stomach pump
*coronary artery bypass grafting (CABG) performed on a beating heart, i.e. without using *cardiopulmonary bypass (the pump refers to a *heart-lung machine).... off-pump cabg
a drug that reduces gastric acid secretion by blocking the *proton pump. Proton-pump inhibitors include esomeprazole, lansoprazole, *omeprazole, pantoprazole, and rabeprazole sodium; they are used for treating gastro-oesophageal reflux disease, peptic ulcer, and acid hypersecretion associated with *gastrinoma.... proton-pump inhibitor
a type of radiotherapy that uses a beam of protons. These charged particles are produced by a *cyclotron and penetrate only a predictable distance into the body depending on the proton energy. This is the radiotherapy treatment of choice for many childhood cancers, particularly brain and spinal tumours, as it can avoid more normal tissue and reduce the risk of long-term complications (including secondary malignancy) compared with photon (X-ray) beams.... proton therapy
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