Prurigo Health Dictionary

(Linn.) Diels.

Synonym: C. villosus (Lam.) DC.

Family: Menispermaceae.

Habitat: Throughout tropical and sub-tropical tracts of India.

English: Broom-Creeper, Ink-Berry.

Ayurvedic: Chhilihinta, Paataala- garuda, Mahaamuulaa, Dirghavalli, Jalajamani.

Siddha/Tamil: Kattukodi.

Action: Root—laxative, sudorific, alterative, antirheumatic. Leaf— used externally for eczema, prurigo and inpetigo. A decoction of leaves is taken in eczema, leucorrhoea and gonorrhoea.

Aqueous extract of stem and root— sedative, anticonvulsant, hypotensive, bradycardiac, cardiotonic and sapas- molytic. Roots are used as a substitute for Sarsaparilla in chronic rheumatism gout, and syphilitic cachexia.

The stem contains cyclopeptide alkaloids. The plant contains coclaurine, magnoflorine, beta-sitosterol, ginnol and a monomethyl ether of inositol.

C.pendulus (Forsk.) Diels, synonym C. leaeba (Del.) DC. (Punjab, Gujarat and South India) is known as Parwati (Gujarat, Sindh) and Ullar-billar (Punjab).

Ethanolic extract of the leaves and stem showed anticancer and hypoten- sive activities associated with the al- kaloidal fraction which contains bis- benzylisoquinoline alkaloids (including pendulin and cocsulin). Presence of quercitol is reported from non- alkaloidal fraction.

Dosage: Root—50-100 ml decoction. (CCRAS.)... cocculus hirsutus

Linn.

Family: Lythraceae.

Habitat: Native to Arabia and Persia; now cultivated mainly in Haryana and Gujarat; to a small extent in Madhya Pradesh and Rajasthan.

English: Henna.

Ayurvedic: Madayanti, Madayan- tikaa, Mendika, Ranjaka.

Unani: Hinaa, Mehndi.

Siddha/Tamil: Marudum.

Action: Leaves—astringent, antihaemorrhagic, antispasmodic, oxytocic, antifertility, antifungal, antibacterial. Used externally to treat skin infections (tinea); also as a hair conditioner.

The Ayurvedic Pharmacopoeia ofIn- dia indicated the use of the leaves in dysuria, jaundice, bleeding disorders, ulcers, prurigo and other obstinate skin diseases. The leaf is also recommended in giddiness and vertigo.

The leaves contain naphthoqui- nones, in particular lawsone; couma- rins (laxanthone, I, II and III); flavono- ids, luteolin and its 7-O-glucoside, acacetin-7-O-glucoside; beta-sitoste- rol-3-O-glucoside; all parts contain tannins.

Chloroform and ethanol extracts of leaves exhibit promising antibacterial activity against Shigella and Vibrio cholerae. Leaf extract shows antifun- gal activity against several pathogenic bacteria and fungi.

Henna paint is used as a medicament for treatment of hands and feet for mycosis. The antimycotic activity is due to lawsone, a naphthoquinone.

The ethanol-water (1 : 1) extract of the stem bark shows hepatoprotective activity CCl4-induced liver toxicity. Stembarkand root, probably due to the presence of isoplumbagin and lawsar- itol, exhibit anti-inflammatory activity experimentally.

Evidence shows Henna leaf might be able to decrease the formation of sickled cells in individuals with sickle cell anaemia. (Natural Medicines Comprehensive Database, 2007.)

Dosage: Leaves—5-10 ml juice. (API, Vol. IV.)... lawsonia inermis

Batsch var. amara (bitter); var. sativa (sweet).

Family: Rosaceae.

Habitat: Cultivated in Kashmir at elevation of 760-2,400 m, also in Himachal Pradesh and Uttar Pradesh.

English: Almond.

Ayurvedic: Vaataama, Vaataada.

Unani: Baadaam Shireen, Loz.

Siddha/Tamil: Vaadumai.

Action: Kernels—nutritious, demulcent and stimulant nervine tonic; valuable in diets for peptic ulcer. Unripe fruits— astringent, applied to gums. Oil—nutritive, demulcent, slightly laxative.

Almond flour made from the residue left after expressing almond oil, and almond butter, is used for the preparation of starch-free diabetic food.

The chief protein of almond is a globulin, amandin, an albumin is also reported. Amandin has a high arginine content (11.9%). The primary chemical difference between the sweet and bitter kernel lies in the high content (2.5-3.5%) of amygdalin in bitter kernel; the ripe sweet almond being free of this cyanogenetic glucoside. Owing to the presence of amygdalin, which on enzymatic hydrolysis yields hydrocyanic acid, the bitter almond is not fit for human consumption.

The oil yield from bitter kernels is usually 38 to 45% and from sweet almond 44 to 55%. The bitter almond oil containing hydrocyanic acid finds limited use in medicine as an antispas- modic and sedative. Dissolved in 50 times water, it is applied externally in prurigo senilis. Hydrocyanic acid-free oil is used for flavouring purposes.

Partial replacement of saturated fatty acids with almonds lowers total plasma cholesterol and low-density lipoprotein cholesterol.... prunus amygdalus

(Decne) Sch.-Bip.

Synonym: S. costus (Falc.) Lipsch.

Family: Compositae; Asteraceae.

Habitat: Kashmir, Himachal Pradesh and Garhwal at 25003,000 m; cultivated in Kashmir and neighbouring regions.

English: Kuth, Costus.

Ayurvedic: Kushtha, Kusht, Vaapya, Kaashmira, Gada, Rug, Ruk, Aamaya, Paalaka. (Substitute: Pushkara Muula, Inula racemosa.)

Unani: Qust.

Siddha/Tamil: Kostum, Kottam.

Folk: Sugandha-Kuutth.

Action: Root—antispasmodic, expectorant, carminative, astringent, antiseptic. An ingredient of prescriptions for dyspepsia, asthma, cough, chronic rheumatism, skin diseases. Applied locally to wounds and ulcerations. Powdered root, mixed with mustard oil, is applied to scalp in prurigo.

The Ayurvedic Pharmacopoeia of India recommends the root in cough, bronchitis, dyspnoea; erysipelas and gout.

The root (containing both the essential oil and alkaloid, saussurine) is used for asthma, particularly of vagotonic type. It produces a definite relaxtion of the bronchioles. The relief obtained is comparable to that of conventional bronchodilators without side effects, like a rise in blood pressure, sweating or headache even on repeated administration.

Saussurine depresses parasympa- thetic nervous system. The aminoacid- sesquiterpene adducts, saussureami- nes A, B and C show antiulcer effect. The aqueous extract of the root exhibits antianginal activity.

Essential oil inhibits peristalic movement of the gut. It is absorbed from the gastro-intestinal tract and partly excreted by lungs producing an expectorant action and partly by the kidneys producing diuretic effect. (In Western herbal, Kuth essential oil is not prescribed internally.)

Kuth roots contain resinoids (6%), and essential oil (1.5%), alkaloid (0.05%) inulin (18%), saussurea lactone (20-25%), a fixed oil and minor constituents like tannin and sugars. Roots obtained from Kashmir are, in general, richer in essential oil content than roots obtained from Garhwal and Nepal. The roots of Punjab variety gave cos- tunolide, dehydrocostuslactone, costic acid, palmitic and linoleic acids, beta- sitosterol and alpha-cyclocostunolide. The Kashmir variety, in addition, gave alantolactone, beta-cyclocostunolide and iso-alantolactone.

The essential oil of the roots exhibit strong antiseptic and disinfectant activity against Streptococcus and Staphy- lococcus.

Costus speciosus Sm. synonym Banksea speciosa, also known as Kush- tha, is a different herb of Zingiberaceae family. Rhizomes and stems yield dios- genin.

Dosage: Root—0.2-1.0 g powder. (API, Vol. I.)... saussurea lappa

n. itching. Mediated by histamine and other vasoactive chemicals, it is the predominant symptom of atopic *eczema, *lichen planus, and many other skin diseases. It also occurs in the elderly and may be a manifestation of psychological illness or infection (such as scabies). Perineal itching is common: itching of the vulva in women is termed pruritus vulvae; itching of the perianal region (pruritus ani) is more common in men. Causes of perineal itching include poor hygiene, *candidiasis, *threadworms, and itchy skin diseases (such as eczema). Pruritus also occurs as a symptom of dry skin and of certain systemic disorders, such as chronic renal failure, *cholestasis, and iron deficiency. Pruritus gravidarum is generalized itching during pregnancy that starts in the first trimester. It is associated with *obstetric cholestasis and requires monitoring of liver function and bile acids, high levels of which endanger the fetus. Other conditions marked by pregnancy-related pruritus include *polymorphic eruption of pregnancy, *prurigo of pregnancy, pruritic folliculitis of pregnancy, and *pemphigoid gestationalis; all of these are associated with a rash. Treatment of pruritus is determined by the cause.... pruritus

Pilocarpus jaborandi

FAMILY: Rutaceae

SYNONYMS: Pernambuco jaborandi, P. pennatifolius, iaborandi, jamborandi, arrudo do mato, arruda brava, jamguaraddi, juarandi.

GENERAL DESCRIPTION: A woody shrub up to 2 metres high with a smooth, greyish bark, large brownish-green leathery leaves containing big oil glands and reddish-purple flowers.

DISTRIBUTION: Native to Brazil; other species are found in Paraguay, Cuba, the West Indies and Central America.

OTHER SPECIES: There are many members of the Rutaceae and Piperaceae family known simply as jaborandi, such as Piper jaborandi. Others include maranham jaborandi (P. microphyllus), ceara jaborandi (P. trachylophus) and aracti jaborandi (P. spicatus).There is consequently some confusion about the exact botanical source of the oil.

HERBAL/FOLK TRADITION: Jaborandi induces salivation and most gland secretions; it was also used at one time to promote hair growth. ‘Useful in psoriasis, prurigo, deafness ... chronic catarrh, tonsillitis and particularly dropsy.’ .

ACTIONS: Antiseptic, diaphoretic, emmenagogue, galactagogue, stimulant (nerve).

EXTRACTION: Essential oil by steam distillation from the dried leaflets.

CHARACTERISTICS: An orange or yellow liquid with a sweet-herbaceous fruity odour.

PRINCIPAL CONSTITUENTS: Pilocarpine is the main active constituent; also isopilocarpine, pilocarpidine, methyl nonyl ketone, dipentene and other hydrocarbons.

SAFETY DATA: Oral toxin, skin irritant, abortifacient.

AROMATHERAPY/HOME: USE None.

OTHER USES: Various hypodermic solutions are prepared from pilocarpine: the crude oil is rarely used. Little used in perfumery or flavour work due to toxicity.... jaborandi