Pyridoxal Phosphate: From 1 Different Sources
a derivative of vitamin B6 that is an important *coenzyme in certain reactions of amino-acid metabolism. See transamination.
Salts of phosphoric acid. As this substance is contained in many articles of food as well as in bone, the nuclei of cells, and the nervous system, phosphates are constantly excreted in the URINE. The continued use of an excess of food containing alkalis, such as green vegetables, and still more the presence in the urine of bacteria which lead to its decomposition, produce the necessary change from the natural mild acidity to alkalinity, and lead to the deposit of phosphates and to their collection into stones.... phosphates
An ENZYME that performs an essential function in the metabolism of CARBOHYDRATE. A de?ciency in this enzyme – acronym G6PD – results in the breakdown of ERYTHROCYTES (HAEMOLYSIS), usually in the presence of oxidants (see OXIDANT) such as infections or drugs. The de?ciency disorder is a hereditary condition in which the enzyme is absent. The condition, characterised by pallor, rigors and pain in the loin, is divided into African, European (including FAVISM) and Oriental types. Sufferers should avoid substances that trigger haemolysis. Acute episodes are best treated symptomatically.... glucose-6-phosphate dehydrogenase
A deficiency in the enzyme G6PD resulting in a haemolytic anaemia. This haemoglobinopathy contraindicates the use of the 4-aminoquinolines such as primaquine for the radical treatment of benign tertian and ovale tertian malaria.... glucose-6-phosphate-dehydrogenase (g6pd) deficiency
a hereditary disorder – an X-linked condition (see sex-linked) – in which the absence of the enzyme glucose-6-phosphate dehydrogenase (G6PD), which functions in carbohydrate metabolism, results in the breakdown of the red blood cells (*haemolysis), usually after exposure to *oxidants, such as drugs, or infections. The breakdown causes acute attacks that are characterized by pallor, loin pain, and rigors. There are several varieties of G6PD deficiency, which is most common in people of African, Middle Eastern, and Mediterranean descent. Treatment involves identifying and avoiding agents that trigger the haemolysis and treating acute attacks symptomatically. See also favism.... glucose-6-phosphate dehydrogenase deficiency
a derivative of *histamine that was formerly used to test for acid secretion in the stomach in conditions involving abnormal gastric acid secretion, such as *Zollinger-Ellison syndrome.... histamine acid phosphate
Health Encyclopedia