one of the lobes of the *liver.
Habitat: North America ; cultivated in Salt Lake City.
Features ? A biennial herb, in height from twelve to eighteen inches, the stem is angular and slightly hairy. One to three inches long, the leaves are alternate, sessile, and ovate-lanceolate, with small, whitish glands on the edge. The fruit is in the form of a flat, oval capsule, which contains ovate-oblong seeds about one eighth of an inch long, brown in colour, with a reticulated, pitted surface. The root is fibrous, and the plant bears a small blue, pointed flower. The taste is burning and acrid like tobacco, the odour slight. Part used ? Herb and seeds are used.Action: Emetic, stimulant, antispasmodic, expectorant, and diaphoretic.
Lobelia inflata has for many years been one of the most widely discussed and hotly debated articles used in medicine. While many herbalists contend that it is the most valuable of all botanic remedies, official medicine in England classifies it as a poison. Herbalists who use Lobelia insist that it is most certainly not a poison, and that it can be administered by them in large doses with perfect safety. They use it chiefly as an emetic, and, as its administration brings about the prompt removal of accumulations of mucus, the action in bronchial complaints is speedy and beneficial. Coffin's comments in this connection are enthusiastic ? "Lobelia is decidedly the most certain and efficient emetic known, and is at the same time safe in its operations. Unlike most emetics from the mineral kingdom, it produces its specific effect without corroding the stomach or producing morbid irritation and inflammation of the mucous membrane of this organ, which are so common in the use of antimony, zinc, and the sulphate of copper. Lobelia may emphatically be said to 'operate in unison with the laws of life'."In view of the controversy surrounding its use, the history of Lobelia is interesting. North American Indians had apparently long been acquaintedwith its properties, but its first introduction to general use was due to the efforts of the famous American, Samuel Thomson. His disciple, Dr. Coffin, brought the herb to this country and used it extensively in his practice for over forty years, apparently with great success "in almost every form of disease, and from the tender infant to the aged," to quote Coffin himself. In both America and Britain herbalists have been tried on charges of causing death by administering Lobelia, but in no instance has a verdict been obtained against them.... lobeliaHabitat: Nepal, Chota Nagpur and Khasi hills at altitudes of 9001,500 m.
Action: Plant—used in China for fevers and asthma. Root—considered depurative and antirheumatic in Indo-China. The plant is one of the constituent of a tincture formulation used for the treatment of scars.
The rhizomes of the plant are reported to contain the polyfructosan, lobelinin.... lobelia chinensisHabitat: Native to eastern United States; imported into India.
English: Indian Tabacco, Pukeweed.Ayurvedic: Devanala (var.).Action: Antiasthmatic, antispasmodic, broncho-dilator, expectorant, mild sedative and relaxant. Used as a tabacco deterrent (as a major ingredient in many antismoking mixtures).
Key application: In the treatment of asthma, bronchitis. (German Commission E.) As respiratory stimulant. (The British Herbal Pharmacopoeia.)Lobelia contains piperidine alkaloids, mainly lobeline, with lobelanine, lobelanidine, norlobelanine, isolobi- nine. Lobeline stimulates respiration in animals by stimulating respiratory centre and at high doses stimulates the vomiting centre.Lobeline has similar but less potent pharmacological properties to nicotine but 1/20-1/5 as potent.Lobeline (0.5%) has also been used as an active ingredient in skin-lightening preparations.Clinical research could not demonstrate lobeline efficacy greater than placebo in smoking cessation. It was disallowed as an ingredient in antismoking products in the US in 1993. (Natural Medicines Comprehensive Database, 2007.)The leaves contain beta-amyrin pal- mitate which possesses sedative and antidepressant properties comparable to the antidepressant drug mianserin. Methanolic extract of leaves exhibited antidepressant activity.The leaf powder is toxic at 0.6-1.0 , (Francis Brinker.)... lobelia inflataHabitat: Hills of South India at altitudes above 1,800 m.
Ayurvedic: Nala (var.).Folk: Devanala (var.) (Maharashtra.)Action: Leaves—filtered solution is used in the control of aphids, tingids and mites on vegetable and other crops. Plant—poisonous to man and livestock. The leaves are cured and smoked as tabacco.... lobelia leschenaultina
Habitat: Deccan, Konkan and Western Ghats, at altitudes of 9002,100 m.
English: Wild Tobacco.Ayurvedic: Devanala, Nala (var.).Siddha/Tamil: Kattuppugaiyilai, Upperichedi.Action: Used as a substitute for Lobelia inflata.
An analysis of Lobelia nicotianae- folia, grown in Maharashtra, shows that the plant contains appreciable quantities of nor-lobelanine and small amounts of lobinine and minor bases.Lobelia cardinalis Linn., Cardinal Flower, is cultivated in Indian gardens. It contains lobinaline as main alkaloid. Lobinaline depresses blood pressure but has no influence on respiration. L. erinus Linn. and L. succulenta Blume, synonym L. affinis Wall. also contain alkaloids with lobinaline 0.445%.Lobelia cordigera Cav., synonym L. fulgens Willd., an ornamental Lobelia sp., grown in Indian gardens, contains inulin.Lobelia pyramidalis Wall. (Himalayas from Kumaon eastwards to Sikkim and Assam at altitudes of900-2,700 m) contains 0.29-0.38% alkaloids as lobeline, and may be used as a substitute for Lobelia inflata.... lobelia nicotianaefolia
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