Unresponsive or resistant to treatment.
Resistant to ordinary treatment or infection.
adj. unresponsive: applied to a condition that fails to respond satisfactorily to a given treatment.
(in neurology) the time of recovery needed for a nerve cell that has just transmitted a nerve impulse or for a muscle fibre that has just contracted. During the refractory period a normal stimulus will not bring about excitation of the cell, which is undergoing *repolarization.... refractory period
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