A complex systemic reaction that may become evident any time up to 14 days after antivenom or antitoxin use. Symptoms are fever, generalised lymphadenopathy and an urticarial rash. Severe cases of serum sickness may have to be treated with oral steroids. The incidence of serum sickness is often related to the amount of antivenom used.... serum sickness
The ?uid which separates from blood, LYMPH, and other body ?uids when clotting occurs (see COAGULATION; HAEMORRHAGE). PLASMA is the ?uid of the blood, including FIBRIN, which carries the circulating blood cells and PLATELETS.
Serum is a clear, yellowish ?uid containing around 7 per cent proteins and globulins, small quantities of salts, fat, sugar, urea, and uric acid, and even smaller quantities of immunoglobulins, essential in the prevention of disease (see IMMUNITY; IMMUNOLOGY). The serum given in the commonly used vaccines is generally derived from horses’ blood, after they have been subjected to a long course of treatment.... serum
(antilymphocyte globulin, ALS, ALG) an *antiserum, containing antibodies that suppress lymphocytic activity, prepared by injecting an animal with lymphocytes. ALS may be given to a patient to prevent the immune reaction that causes tissue rejection following transplantation of such organs as kidneys or of bone marrow. Administration naturally also impairs other immunity mechanisms, making infection a serious hazard.... antilymphocyte serum
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