Restenosis Health Dictionary

Restenosis: From 1 Different Sources


Brachytherapy

n. radiotherapy administered by implanting a radioactive source into or close to a tumour. This technique is used in the treatment of many accessible tumours (e.g. gynaecological cancers) and is increasingly used in the treatment of localized prostate cancer. Intravascular brachytherapy has been used to prevent *restenosis in stented coronary arteries but this technique has been obviated by the introduction of drug-eluting *stents.... brachytherapy

Neointimal Hyperplasia

a pathological process involved in *atherosclerosis of arteries and vein grafts, and in *restenosis, that may be in response to angioplasty and stent placement. Damage to the endothelium of the artery exposes the underlying smooth muscle cells in the *media to cytokines, growth factors, and other plasma components in the circulation, which results in loss of their contractile characteristics. These abnormal muscle cells migrate to the *intima, where they proliferate and eventually form a thick layer of tissue (neointima), which occludes the artery.... neointimal hyperplasia



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