Risk–benefit Analysis: From 2 Different Sources
The process of analysing and comparing, on a single scale, the expected positive (benefits) and negative (risks, costs) results of an action, or lack of an action.
an analytical process used to weigh up the probability of foreseeable risks and benefits of an action or policy. In medical ethics, it provides a means of reconciling the principles of *beneficence and *nonmaleficence where a particular intervention has dangers as well as benefits. Compare cost–benefit analysis. See also consequentialism.
An aspect of personal behaviour or lifestyle, an environmental exposure, or an inborn or inherited characteristic, which, on the basis of scientific evidence, is known to be associated with health-related condition(s) considered important to prevent.... risk factor
A statistical procedure to combine results from different studies on a similar topic. The combination of results from multiple studies may produce a stronger conclusion than can be provided by any singular study. Meta-analysis is generally most appropriate when there are no definitive studies on a topic and non-definitive studies are in some disagreement.... meta-analysis
The function of identifying and assessing problems that could occur and bring about losses legally, clinically or financially.... risk management
Analysis means a separation into component parts by determination of the chemical constituents of a substance. The process of analysis is carried out by various means, for example: chromatographic analysis by means of the adsorption column; colorimetric analysis by means of various colour tests; densimetric analysis by estimation of the speci?c gravity; gasometric analysis by estimation of the di?erent gases given o? in some process; polariscope analysis by means of the polariscope; and volumetric analysis by measuring volumes of liquids. Analysis is also sometimes used as an abbreviation for PSYCHOANALYSIS.... analysis
See RISK REGISTER.... at-risk register
The systematic comparison, in monetary terms, of all the costs and benefits of proposed alternative schemes with a view to determining: which scheme or combination of schemes will contribute most to the achievement of predetermined objectives at a fixed level of investment; or the magnitude of the benefit that can result from schemes requiring the minimum investment. The resources required per unit of benefit must be determined, account being taken of the fact that costs and benefits accrue with time. For example, the cost of establishing a home and community care programme might be compared with the total cost of building residential facilities. Cost-benefit analysis can also be applied to specific medical tests and treatments.... cost-benefit analysis
The additional benefit (e.g. in units of health outcome) produced by an additional resource use (e.g. another health care intervention).... marginal benefit
A set of techniques used when the variation in several variables has to be studied simultaneously. In statistics, any analytic method that allows the simultaneous study of two or more independent variables.... multivariate analysis
The probability that an event will occur.... risk
The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences.... risk assessment
The probability of an event in a population as contrasted with relative risk. See “relative risk”.... absolute risk
A measure of treatment effect that compares the probability (or mean) of a type of outcome in the control group with that of a treatment group.... absolute risk reduction
A risk that has minimal detrimental effects or for which the benefits outweigh the potential hazards.... acceptable risk
In a total population, the proportion of disease incidence, or risk of the disease, that can be attributed to exposure to a specific risk factor; the difference between the risk in the total population and the risk in the unexposed group.... attributable risk
Non-cash forms of payment or assistance.... benefit in kind
Initially driven by anxiety about the possibility of medical negligence cases, clinical risk management has evolved into the study of IATROGENIC DISEASE. The ?rst priority of risk managers is to ensure that all therapies in medicine are as safe as possible. Allied to this is a recognition that errors may occur even when error-prevention strategies are in place. Lastly, any accidents that occur are analysed, allowing a broader understanding of their cause. Risk management is generally centred on single adverse events. The threat of litigation is taken as an opportunity to expose unsafe conditions of practice and to put pressure on those with the authority to implement change. These might include senior clinicians, hospital management, the purchasing authorities, and even the Secretary of State for Health. Attention is focused on organisational factors rather than on the individuals involved in a speci?c case.... clinical risk management
A systematic analysis of the content rather than the structure of a communication, such as a written work, speech or film, including the study of thematic and symbolic elements to determine the objective or meaning of the communication.... content analysis
A determination of the least costly among alternative interventions that are assumed to produce equivalent outcomes.... cost minimization analysis
The relationship between the cost of an activity and the benefit that accrues from it.... cost-benefit
A form of analysis that seeks to determine the costs and effectiveness of a health intervention compared with similar alternative interventions to determine the relative degree to which they will obtain the desired health outcome(s).... cost-effectiveness analysis
A determination of the economic impact of a disease or health condition, including treatment costs.... cost-of-illness analysis
A form of cost-effectiveness analysis of alternative interventions in which costs are measured in monetary units and outcomes are measured in terms of their utility, usually to the individual, e.g. using QALYs.... cross-utility analysis
An approach to decision-making that involves modelling the sequences or pathways of multiple possible strategies (e.g. of diagnosis and treatment for a particular clinical problem) to determine which is optimal. It is based upon available estimates (drawn from the literature or from experts) of the probabilities that certain events and outcomes will occur and the values of the outcomes that would result from each strategy.... decision analysis
The process of gathering, analysing and comparing an individual’s prognostic health characteristics with a standard age group, thereby predicting the likelihood that a person may develop a health problem.... health risk appraisal
A chemical, psychological, physiological, social, environmental or genetic factor or conditions that predisposes an individual to the development of a disease or injury.... health risk factor
A school of ‘analytical psychology’, ?rst described by Carl Gustav Jung in 1913. It introduced the concepts of ‘introvert’ and ‘extrovert’ personalities, and developed the theory of the ‘collective unconscious’ with its archetypes of man’s basic psychic nature. In contrast with Freudian analysis (see FREUDIAN THEORY), in Jungian analysis the relationship between therapist and patient is less one-sided because the therapist is more willing to be active and to reveal information about him or herself. (See also PSYCHOANALYSIS.)... jungian analysis
The Industrial Injuries Scheme provides money for people who have suffered injury or illness because of their work. Bene?ts for employment-related disability (selfemployment is excluded) have been altered many times since they were introduced in 1948. There is now a mix of bene?ts, eligibility for which depends on several factors: the date, onset and type of disability are among the most important. ‘Industrial’ includes almost all forms of employment. In addition to accidents, there is a long list of prescribed industrial diseases ranging from BURSITIS, hearing loss, ASTHMA and viral HEPATITIS to unusual ones such as ORF. Psychological as well as physical disablement may attract bene?t, which is calculated on a percentage basis according to the extent of disability. The onus is on the individual to claim, and trade unions and representative organisations can advise on procedures. Injured employees should always report details of an accident to their employer and record it in the accident book promptly: even seemingly minor injuries may subsequently lead to some disability. Relevant information lea?ets are available – for example, from local bene?t agencies, local-authority advice centres and public libraries.... industrial injuries benefit
More than one risk factor for the development of a disease or other outcome is present and their combined presence results in an increased risk. The increased risk may be due to the additive effects of the risks associated with the separate risk factors, or to synergism.... multiple risk / causation
Review and analysis of practice profiles to identify and assess patterns of health care services.... profile analysis or profiling
A tool to estimate the relationships among a dependent variable Y and one (or many) independent variable(s) X. The purpose of regression analysis is to find the “best fit” data points from a straight line drawn on an XY graph.... regression analysis
The ratio of the risk of disease or death among the exposed to the risk among the unexposed; this usage is synonymous with risk ratio.... relative risk
An approach consisting of identifying and devoting more care to individuals or groups who, for biological, environmental or socioeconomic reasons, are at special risk of having their health impaired, contracting a specific disease, or having inadequate attention paid to their health problems.... risk approach
The practice of bringing several risks together for insurance purposes in order to balance the consequences of the realization of each individual risk.... risk pooling
Risk rating means that high-risk individuals will pay more than the average premium price.... risk rating
The practice of singling out or disaggregating a particular risk from a pool of insured risks.... risk selection
The distribution of financial risk among parties furnishing a service. For example, if a hospital and a group of medical practitioners form a corporation to provide health care at a fixed price, a risk-sharing arrangement would entail both the hospital and the group being held liable if expenses were to exceed revenues.... risk sharing
A process for identifying the basic or causal factor(s) that underlie variations in performance, including the occurrence or possible occurrence of an error.... root-cause analysis
This type of analysis utilizes existing data sources either through synthesis or integration; meta-analysis is an example of secondary data analysis.... secondary data analysis
The unit to which a performance measure is applied (e.g. subjects, patients, clinicians, group of professionals).... unit (of analysis)
Hair is believed to be a “time capsule” of a person’s metabolic activity. Believed to be a useful means of acquiring information regarding the concentration of mineral nutrients and toxins. Alone, it does not provide sufficient evidence for purposes of diagnosis, but helpful in building a picture of the nutritional state of the patient. ... hair analysis
Determination of the identity of a substance or of the individual chemical constituents of a mixture. Analysis may be qualitative, as in determining whether a particular substance is present, or it may be quantitative, that is, measuring the amount or concentration of one or more constituents. (See also assay.)... analysis, chemical
See psychoanalysis.... analysis, psychological
an assessment tool that predicts a ten-year risk of developing cardiovascular disease based on gender, age, total and HDL cholesterol, blood pressure, and smoking, thereby enabling preventative treatment. It does not incorporate the presence of diabetes or familial history of cardiovascular disease into the scoring.... framingham risk score
a state benefit payable to a person disabled by injury or a prescribed industrial disease sustained or contracted in the course of employment (see occupational disease; prescribed disease). The benefit is payable as a weekly amount. The amount of the benefit depends on the degree of disablement as determined following assessment by a specialist. To be entitled to benefit, the disablement must be assessed as being at least 20% of total disability (1% in the case of pneumoconiosis, byssinosis, and diffuse mesothelioma). The benefit is payable if the claimant is still suffering disability two months or more after the date of the accident or onset of the disease. It is payable for a period assessed as the time for which the claimant is likely to suffer the disability. The assessment can be reviewed if the claimant’s condition deteriorates or if he or she is still disabled at the end of the period of assessment.... industrial injuries disablement benefit
a research process in which results are reported according to the treatment arm to which a research subject was assigned, rather than the treatment eventually received. Intention to treat analysis is very widely used in clinical research as a method of avoiding *bias resulting from nonrandom withdrawal from the trial or crossover between treatment arms.... intention to treat analysis
a technique for identifying a specific form of messenger RNA in cells. It uses a gene *probe known to match the RNA being sought. Compare Southern blot analysis; Western blot analysis.... northern blot analysis
(RMI) a scoring system that combines ultrasound findings, menopausal status and age, and serum CA125 levels to give an estimate of the risk of malignancy in a woman with a mass in the Fallopian tubes or ovaries. If the total RMI score is <200 the risk of malignancy is considered to be low. If the total RMI score is >200 the chances of malignancy are raised and management should be planned with a gynaecological oncologist.... risk of malignancy index
analysis of a specimen of semen, which should be obtained after five days of abstinence from coitus, in order to assess male fertility. Normal values are as follows: volume of ejaculate: 2–6.5 ml; liquefaction complete in 30 minutes; sperm concentration: 20–200 million spermatozoa per ml (sperm count refers to the total number of spermatozoa in the ejaculate); motility: 60% moving progressively at 30 minutes to 3 hours; abnormal forms: less than 20%. Analysis of three separate specimens is necessary before confirming the presence of an abnormal result.... seminal analysis
a framework for exploring how care is delivered, based on the idea that there are six main styles of interaction (prescriptive, informative, confronting, cathartic, catalytic, and supportive). The analysis is widely used to help health-care professionals develop an understanding of interpersonal relationships, reflect on their own practice, and enhance their interactions with clients.... six-category intervention analysis
a technique for identifying a specific form of DNA in cells. The DNA is extracted from the cells and restriction enzymes used to cut it into small fragments. The fragments are separated and a gene *probe known to match the DNA fragment being sought is used. Compare Northern blot analysis; Western blot analysis. [E. M. Southern (1938– ), US biologist]... southern blot analysis
a technique for the detection of specific proteins. After separation by *electrophoresis, the proteins are bound to radioactively labelled antibodies and identified by X-ray. Compare Northern blot analysis; Southern blot analysis.... western blot analysis
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