Serotonin agonists Health Dictionary

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Serotonin Agonists: From 1 Different Sources

A group of drugs, also known as 5HT1 agonists, used to treat acute attacks of migraine.

They work on the same receptors in the brain as 5 hydroxytryptamine (5HT), a neurotransmitter and vasodilator.

Common serotonin agonists include naratriptan and sumatriptan.

These drugs can cause chest pain, particularly in people with heart disease.

They should be used with caution in those at increased risk of coronary artery disease.

Other side effects include flushing, tingling, and nausea.

Health Source: BMA Medical Dictionary
Author: The British Medical Association

Serotonin

Also known as 5-hydroxytryptamine, this is a substance widely distributed in the body tissue, but especially in the PLATELETS in the blood, the lining of the gastrointestinal tract, and the BRAIN. Serotonin is believed to have a similar function to that of HISTAMINE in INFLAMMATION. In the gut it inhibits gastric secretion and stimulates smooth (involuntary) muscle in the walls of the INTESTINE. Serotonin participates in the transmission of nerve impulses and may have a function in controlling mood and states of consciousness. (See also SELECTIVE SEROTONIN-REUPTAKE INHIBITORS (SSRIS).)... serotonin

Selective Serotonin-reuptake Inhibitors (ssris)

These ANTIDEPRESSANT DRUGS have few antimuscarinic effects (see ANTIMUSCARINE), but do have adverse effects of their own – predominantly gastrointestinal. They are, however, much safer in overdose than the tricyclic antidepressants, which is a major advantage in patients who are potentially suicidal. Examples are citalopram, used to treat panic disorders, as well as depressive illness; FLUOXETINE; and PAROXETINE. (See also MENTAL ILLNESS.)... selective serotonin-reuptake inhibitors (ssris)

Selective Serotonin Reuptake Inhibitors

(SSRIs) A relatively new class of drugs that are used to treat depression.

They work by blocking the reabsorption of the neurotransmitter serotonin following its release in the brain.

The increased serotonin levels that result are associated with improved mood.

Common drugs in this group include fluoxetine and sertraline.

SSRIs are usually taken orally once a day; it may take 1–3 weeks for any noticeable improvement in symptoms.

SSRIs usually produce fewer side effects than other types of antidepressant drug.

However, they may cause diarrhoea, nausea, restlessness, and anxiety.... selective serotonin reuptake inhibitors

Serotonin Antagonists

A group of drugs used to treat the nausea and vomiting caused by radiotherapy and anticancer drugs. They are also used to control nausea and vomiting following surgery. Common serotonin antagonists include granisetron and ondansetron.... serotonin antagonists

Glp-1 Receptor Agonists

a group of drugs used in the treatment of type 2 diabetes. They mimic the actions of *glucagon-like peptide-1 in regulating the rise in blood glucose levels after eating and they also enhance satiety (see incretin). As these drugs respond to a falling blood glucose level there is a reduced tendency to *hypoglycaemia compared with *sulphonylurea drugs and insulin therapy itself. They are given by subcutaneous injection and three of them are licensed for use in the UK: exenatide (Byetta; twice daily dosing), liraglutide (Victoza; once daily dosing), and lixisenatide (Lyxumia; once daily dosing).... glp-1 receptor agonists

Selective Serotonin And Noradrenaline Reuptake Inhibitor

see SNRI.... selective serotonin and noradrenaline reuptake inhibitor

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