n. a rare tumour of the *islets of Langerhans that produces excessive amounts of somatostatin. It is an example of an *apudoma. In severe cases it can cause the somatostatinoma syndrome, consisting of diabetes, gall-bladder disease, and *steatorrhoea due to malabsorption.
n. a tumour that contains *APUD cells and may give rise to symptoms caused by excessive production of the hormones and other peptides that these cells produce. *Carcinoids are a good example of this group of tumours, but there are many others (e.g. *gastrinomas, *somatostatinomas, and *VIPomas).... apudoma
any tumour arising in a cell of the pancreatic *islets of Langerhans. These tumours, which include *insulinomas, *glucagonomas, and *somatostatinomas, form one of the two major subclasses of gastrointestinal neuroendocrine tumours, the other being the *carcinoid tumours.... islet cell tumour
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