Sympathomimetic Health Dictionary

Sympathomimetic: From 2 Different Sources


A substance that mimics at least part of adrenalin or catecholamine responses. The term is a little biased towards the minority of sympathetic functions that are adrenergic. A better name might be adrenalomimetic, epinephromimetic, catecholamimetic...or speedomimetic. Examples: coffee, ephedrine, amphetamines.
Health Source: Herbal Medical
Author: Health Dictionary
adj. having the effect of stimulating the *sympathetic nervous system. The actions of sympathomimetic drugs are adrenergic: they act on alpha or beta *adrenoceptors. Alpha-adrenergic stimulants (alpha agonists) stimulate alpha receptors. They include *vasoconstrictors (e.g. *ephedrine, *phenylephrine, *metaraminol), used to treat nasal congestion and severe hypotension, and the selective ?2 agonists *apraclonidine and *brimonidine, which are used in the treatment of glaucoma. Beta-adrenergic stimulants (beta agonists) stimulate ?1 and/or ?2 adrenoceptors. ?2 agonists such as *salbutamol, *salmeterol, and *terbutaline relax bronchial smooth muscle and are used as *bronchodilators. Some ?2 agonists, including salbutamol, relax uterine muscle and are sometimes used in the treatment of premature labour (see tocolytic). ?1 agonists (e.g. *dobutamine) stimulate ?1 receptors in the heart and are therefore used for their *inotropic effects.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Sympathomimetic Drugs

These drugs stimulate the activity of the SYMPATHETIC NERVOUS SYSTEM. There are three groups: inotropic and vasoconstrictor sympathomimetics, and those used for cardiopulmonary resuscitation. The properties of these drugs vary according to whether they act on alpha or beta adrenergic receptors.

Inotropics act on beta receptors in heart muscle (see HEART), increasing its contractility and sometimes the heart rate. DOBUTAMINE and DOPAMINE are cardiac stimulants, while dopexamine acts on heart muscle and, via peripheral dopamine receptors, increases the excretion of URINE. ISOPRENALINE is used only as emergency treatment of heart block (interruption of the heart’s conduction) or severe slowing of the heart rate (bradycardia).... sympathomimetic drugs

Vasoconstrictor Sympathomimetics

These drugs temporarily raise the BLOOD PRESSURE by constricting peripheral blood vessels. Sometimes they are used as a speedy way of raising blood pressure when other treatment has failed. EPHEDRINE and methoxamine hydrochloride are examples of this type of sympathomimetic.

Cardiopulmonary resuscitation ADRENALINE (epinephrine) is given intravenously in cardiac arrest, and other drugs used include ATROPINE and CALCIUM.... vasoconstrictor sympathomimetics




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