Rapidly developing TOLERANCE to a drug.
n. a falling-off in the effects produced by a drug during continuous use or constantly repeated administration, common in drugs that act on the nervous system.
n. the reduction or loss of the normal response to a drug or other substance that usually provokes a reaction in the body. Drug tolerance 1. may develop after taking a particular drug over a long period of time. In such cases increased doses are necessary to produce the desired effect. Some drugs that cause tolerance also cause *dependence. See also glucose tolerance test; immunological tolerance; tachyphylaxis. 2. acceptance of others whose beliefs, customs, behaviour, or lifestyle are different from one’s own or from accepted social norms. Tolerance is an indispensable virtue in all medical staff and may be of clinical importance when a patient displays unusual behaviour during initial assessment.... tolerance
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