Tamarind (Tamarindus indica).Plant Part Used: Fruit pulp, leaf, root, branch.Dominican Medicinal Uses: Fruit pulp: aqueous extract, orally, for insomnia, hormonal imbalance, hot flashes and nightsweats. Leaf, bark, branch: decoction, orally, liver, kidney and prostate disorders and hepatitis.Safety: Fruit pulp: widely consumed and generally considered safe; fruit or seed pods may contain an irritating, hypoglycemic alkaloid. Bark/leaves: insufficient information available.Drug Interactions: Ibuprofen (fruit extract increases bioavailability).Laboratory & Preclinical Data: In vivo: antidiabetic (seed extract), anti-inflammatory (plant extracts), colonic cell proliferation effects (fruit pulp).In vitro: antioxidant (plant extract).* See entry for Tamarindo in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.