Abnormal ERYTHROCYTES which are large and ‘?oppy’ and have a ringed appearance, similar to that of a target, when stained and viewed under the microscope. This change from normal may occur with iron-de?ciency ANAEMIA, liver disease, a small SPLEEN, haemoglobinopathies (disorders of HAEMOGLOBIN), and THALASSAEMIA.
A target cell is also a cell that is the focus of attack by macrophages (killer cells – see MACROPHAGE) or ANTIBODIES; it may also be the site of action of a speci?c hormone (see HORMONES).... target cell
The speci?c organ (or tissue) at which a hormone (see HORMONES), drug or other agent is aimed to bring about its physiological or pharmacological e?ect.... target organ
The group of persons for whom an intervention is planned. For example, the targeting of services to particular user groups.... targeting / target population / target group
red spots on the palm of the hands caused by a bacterial infection of the heart (see endocarditis). [E. G. Janeway (1841–1911), US physician]... janeway lesions