the formation of thrombi in arterioles and capillaries, leading to haemolytic anaemia and *thrombocytopenia. The term encompasses primary *haemolytic uraemic syndrome and *thrombotic thrombocytopenic purpura, as well as the microangiopathies that can complicate pregnancy (pregnancy-related haemolytic uraemic syndrome, *HELLP syndrome), *malignant hypertension, *scleroderma, *antiphospholipid antibody syndrome, organ transplantation, and cancer.
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