A number of co-factors are necessary for AIDS to develop: diet, environment, immoral lifestyle, drugs, etc also dispose to the disease which, when eliminated, suggest that AIDS needs not be fatal. However, there is no known cure. Smoking hastens onset. Causes include needle-sharing and sexual contacts. Also known as the ‘Gay Plague’ it can be transmitted from one member of the family to another non-sexual contact.
The virus kills off cells in the brain by inflammation, thus disposing to dementia.
Symptoms. Onset: brief fever with swollen glands. “Feeling mildly unwell”. This may pass off without incident until recurrence with persistent diarrhoea, night sweats, tender swollen lymph nodes, cough and shortness of breath. There follows weight loss, oral candida. Diagnosis is confirmed by appearance of ugly skin lesions known as Kaposi’s sarcoma – a malignant disease. First indication is the appearance of dark purple spots on the body followed by fungoid growths on mouth and throat.
While some cases of STDs have been effectively treated with phytotherapy, there is evidence to suggest it may be beneficial for a number of reasons. Whatever the treatment, frequent blood counts to monitor T-4 cells (an important part of the immune system) are necessary. While a phytotherapeutic regime may not cure, it is possible for patients to report feeling better emotionally and physically and to avoid some accompanying infections (candida etc).
Treatment. Without a blood test many HIV positives may remain ignorant of their condition for many years. STD clinics offer free testing and confidential counselling.
Modern phytotherapeutic treatment:–
1. Anti-virals. See entry.
2. Enhance immune function.
3. Nutrition: diet, food supplements.
4. Psychological counselling.
To strengthen body defences: Garlic, Echinacea, Lapacho, Sage, Chlorella, Reisha Mushroom, Shiitake Mushroom. Of primary importance is Liquorice: 2-4 grams daily.
Upper respiratory infection: Pleurisy root, Elecampane.
Liver breakdown: Blue Flag root, Milk Thistle, Goldenseal.
Diarrhoea: Bayberry, Mountain Grape, American Cranesbill, Slippery Elm, lactobacillus acidophilus.
Prostatitis: Saw Palmetto, Goldenrod, Echinacea.
Skin lesions: External:– Comfrey, Calendula or Aloe Vera cream.
To help prevent dementia: a common destructive symptom of the disease: agents rich in minerals – Alfalfa, Irish Moss, Ginkgo, St John’s Wort, Calcium supplements.
Nervous collapse: Gotu Kola, Siberian Ginseng, Oats, Damiana.
Ear Inflammation: Echinacea. External – Mullein ear drops.
With candida: Lapacho tea. Garlic inhibits candida.
Anal fissure: Comfrey cream or Aloe Vera gel (external).
Practitioner: Formula. Liquid extract Echinacea 30ml (viral infection) . . . Liquid extract Poke root 10ml (lymphatic system) . . . Liquid extract Blue Flag root 10ml (liver stimulant) . . . Tincture Goldenseal 2ml (inflamed mucous membranes) . . . Liquid extract Guaiacum 1ml (blood enricher) . . . Decoction of Sarsaparilla to 100ml. Sig: 5ml (3i) aq cal pc.
Gargle for sore throat: 5-10 drops Liquid extract or Tincture Echinacea to glass water, as freely as desired.
Abdominal Castor oil packs: claimed to enhance immune system.
Chinese medicine: Huang Qi (astragalus root).
Urethral and vaginal irrigation: 2 drops Tea Tree oil in strong decoction Marshmallow root: 2oz to 2 pints water. Inject warm.
Diet. Vitamin C-rich foods, Lecithin, Egg Yolk, Slippery Elm gruel, Red Beet root, Artichokes. Garlic is particularly indicated as an anti-infective.
Nutrition. Vitamin A is known to increase resistance by strengthening the cell membrane; preferably taken as beta carotene 300,000iu daily as massive doses of Vitamin A can be toxic. Amino acid – Glutathione: Garlic’s L-cysteine relates.
Vitamin C. “The virus is inactivated by this vitamin. Saturating cells infected with the HIV virus with the vitamin results in 99 per cent inactivation of the virus. The vitamin is an anti-viral and immune system modulator without unwanted side-effects. The ascorbate, when added to HIV cells, substantially reduced the virus’s activity without harming the cells at specific concentrations. Patients taking large doses report marked improvement in their condition. Minimum daily oral dose: 10 grams.” (Linus Pauling Institute, Science and Medicine, Palo Alto, California, USA)
Periwinkle. An anti-AIDS compound has been detected in the Madagascan Periwinkle (Catharanthus roseus), at the Chelsea Physic Garden.
Mulberry. The black Mulberry appears to inhibit the AIDS virus.
Hyssop. An AIDS patient improved to a point where ulcers were healed, blood infection eliminated, and Kaposi’s sarcoma started to clear when her mother gave her a traditional Jamaican tea made from Hyssop, Blessed Thistle and Senna. From test-tube research doctors found that Hyssopus officinalis could be effective in treatment of HIV/AIDS. (Medical Journal Antiviral Research, 1990, 14, 323-37) Circumcision. Studies have shown that uncircumcised African men were more than five to eight times more likely to contract AIDS than were circumcised men; life of the virus being short-lived in a dry environment. (Epidemiologist Thomas Quinn, in Science Magazine)
Study. A group of 13 HIV and AIDS patients received 200mg capsules daily of a combination of Chelidonium (Greater Celandine) 175mg; Sanguinaria (Blood root) 5mg; and Slippery Elm (Ulmus fulva) 20mg. More than half the patients enjoyed increased energy and improved immune function with reduction in both size and tenderness of lymph nodes. (D’Adamo P. ‘Chelidonium and Sanguinaria alkaloids as anti-HIV therapy. Journal of Naturopathic Medicine (USA) 3.31-34 1992)
Bastyr College of Naturopathy, Seattle, MA, USA. During 1991 the College carried out a study which claimed that a combination of natural therapies including nutrition, supplements, herbal medicine, hydrotherapy and counselling had successfully inhibited HIV and other viral activity in all patients in controlled trials lasting a year.
Patients chosen for the trial were HIV positive, not on anti-viral drugs and showing symptoms of a compromised immune system, but without frank AIDS (generally taken to be indicated by Karposi’s sarcoma and/or PCP-pneumocystitis carinii pneumonia).
Symptoms included: Lymphadenopathy in at least two sites, oral thrush, chronic diarrhoea, chronic sinusitis, leukoplakia, herpes, night sweats and fatigue.
Assessment was subjective and objective (including T-cell ratio tests). The patients did better than comparable groups in published trials using AZT.
Treatment was naturopathic and herbal. Patients receiving homoeopathy and acupuncture did not do as well as those receiving herbs.
Best results with herbs were: Liquorice (1g powder thrice daily); St John’s Wort (Yerba prima tablets, 3, on two days a week only). Patients reported a great increase in the sense of well-being on St John’s Wort. An equivalent dose of fresh plant tincture would be 10ml. The tincture should be of a good red colour. The College did not use Echinacea, which would stimulate the central immune system and which would therefore be contra-indicated.
Supplements given daily. Calcium ascorbate 3g+ (to bowel tolerance). Beta-carotene 300,000iu. Thymus gland extract tablets 6. Zinc 60mg (with some Copper). B-vitamins and EFAs.
To control specific symptoms: most useful herbs were: Tea Tree oil for fungal infections; Goldenseal and Gentian as bitters. Ephedra and Eyebright for sinusitis. Carob drinks for non-specific enteritis. Vitamin B12 and topical Liquorice for shingles.
Counselling and regular massage were used to maintain a positive spirit. Studies show all long term HIV positive survivors have a positive attitude and constantly work at empowering themselves.
Results showed significant improvements in symptoms suffered by HIV patients despite a slow deterioration in blood status. Methods used in the study had dramatically reduced mortality and morbidity. A conclusion was reached that AIDS may not be curable but it could be manageable. (Reported by Christopher Hedley MNIMH, London NW1 8JD, in Greenfiles Herbal Journal) ... aids
Constituents: Myrrhol (volatile oil).
A leuco-cytogenic agent – increases number of white cells in the blood. “From the days of Moses to the time of Christ and since then to the 20th century, Myrrh has proven over and over again to be one of the finest antibacterial and antiviral agents placed on earth.” (John Heinerman, in Science of Herbal
Medicine)
Action: bacteriostatic against staphylococcus aureus and other gram-positive bacteria. Perhaps the most widely used herbal antiseptic. Bitter, astringent, anti-inflammatory, carminative, vulnerary, antifungal, expectorant, diaphoretic, deodorant, emmenagogue, anti-thrush.
Uses: The whole body feels its influence. Internal and external ulceration; especially of mouth, throat, pharynx, spongy gums, pyrrhoea, etc (mouth wash and gargle). Candida – 5-10 drops emulsified in yoghurt. Suppurating wounds that refuse to heal, boils, abscesses. Fungal infections. Myrrh is effective in lowering blood fats and therefore useful for reducing deposits of cholesterol and triglycerides in coronary heart disease. Powerful antiseptic combination: equal parts powders or tinctures: Echinacea, Goldenseal and Myrrh.
Capsicum and Myrrh. Capsicum enhances its action. The two are synergistic and capillary stimulants. Both may be used with impressive effect for chronic conditions along the alimentary canal.
Preparations: Thrice daily.
Tincture Myrrh BPC 1973: 1:5, 90 per cent alcohol. Dose: 5 to 15 drops.
Thomson’s Tincture of Myrrh Co (as once used by members of the National Institute of Medical Herbalists). 1 part Tincture Capsicum BPC to 4 parts Tincture Myrrh. Dose: 1 to 2 and a half ml. Powders: Fill number 00 capsules. 1 capsule thrice daily. May be used as a dusting powder on wounds. Enema. Add 20-30 drops Tincture Myrrh to 2 pints boiling water; allow to cool, inject warm. Contra- indications: pregnancy. ... myrrh
Both HIV-1 and HIV-2 are predominantly sexually transmitted and both are associated with secondary opportunistic infections. However, HIV-2 seems to result in slower damage to the immune system. HIV-1 is known to mutate rapidly and has given rise to other subtypes.
HIV is thought to have occurred in humans in the 1950s, but whether or not it infected humans from another primate species is uncertain. It became widespread in the 1970s but its latency in causing symptoms meant that the epidemic was not noticed until the following decade. Although it is a sexually transmitted disease, it can also be transmitted by intravenous drug use (through sharing an infected needle), blood transfusions with infected blood (hence the importance of e?ective national blood-screening programmes), organ donation, and occupationally (see health-care workers, below). Babies born of HIV-positive mothers can be infected before or during birth, or through breast feeding.
Although HIV is most likely to occur in blood, semen or vaginal ?uid, it has been found in saliva and tears (but not sweat); however, there is no evidence that the virus can be transmitted from these two body ?uids. There is also no evidence that HIV can be transmitted by biting insects (such as mosquitoes). HIV does not survive well in the environment and is rapidly destroyed through drying.
Prevalence At the end of 2003 an estimated 42 million people globally were infected with HIV – up from 40 million two years earlier. About one-third of those with HIV/AIDS are aged 15–24 and most are unaware that they are carrying the virus. During 2003 it is estimated that 5 million adults and children worldwide were newly infected with HIV, and that 3 million adults and children died. In Africa in 2003,
3.4 million people were newly infected and 2.3 million died, with more than 28 million carrying the virus. HIV/AIDS was the leading cause of death in sub-Saharan Africa where over half of the infections were in women and 90 per cent of cases resulted from heterosexual sex. In some southern African countries, one in three pregnant women had HIV.
In Asia and the Paci?c there were 1.2 million new infections and 435,000 deaths. The area with the fastest-growing epidemic is Eastern Europe, especially the Russian Federation where in 2002 around a million people had HIV and there were an estimated 250,000 new infections, with intravenous drug use a key contributor to this ?gure. Seventy-?ve per cent of cases occurred in men, with male-to-male sexual transmission an important cause of infection, though heterosexual activity is a rising cause of infection.
At the end of 2002 the UK had an estimated 55,900 HIV-infected adults aged between 15 and 59. More than 3,600 individuals were newly diagnosed with the infection in 2000, the highest annual ?gure since the epidemic started
– in 1998 the ?gure was 2,817 and in 1999 just over 3,000 (Department of Health and Communicable Disease Surveillance Centre). The incidence of AIDS in the UK has declined sharply since the introduction of highly active antiretroviral therapy (HAART) and HIV-related deaths have also fallen: in 2002 there were 777 reported new AIDS cases and 395 deaths, compared with 1,769 and 1,719 respectively in 1995. (Sources: UNAIDS and WHO, AIDS Epidemic Update, December 2001; Public Health Laboratory Services AIDS and STD Centre Communicable Disease Surveillance and Scottish Centre for Infection and Environmental Health, Quarterly Surveillance Tables.)
Poverty is strongly linked to the spread of AIDS, for various reasons including lack of health education; lack of e?ective public-health awareness; women having little control over sexual behaviour and contraception; and, by comparison with the developed world, little or no access to antiretroviral drugs.
Pathogenesis The cellular target of HIV infection is a subset of white blood cells called T-lymphocytes (see LYMPHOCYTE) which carry the CD4 surface receptor. These so-called ‘helper T-cells’ are vital to the function of cell-mediated immunity. Infection of these cells leads to their destruction (HIV replicates at an enormous rate – 109) and over the course of several years the body is unable to generate suf?cient new cells to keep pace. This leads to progressive destruction of the body’s immune capabilities, evidenced clinically by the development of opportunistic infection and unusual tumours.
Monitoring of clinical progression It is possible to measure the number of viral particles present in the plasma. This gives an accurate guide to the likely progression rate, which will be slow in those individuals with fewer than 10,000 particles per ml of plasma but progressively more rapid above this ?gure. The main clinical monitoring of the immune system is through the numbers of CD4 lymphocytes in the blood. The normal count is around 850 cells per ml and, without treatment, eventual progression to AIDS is likely in those individuals whose CD4 count falls below 500 per ml. Opportunistic infections occur most frequently when the count falls below 200 per ml: most such infections are treatable, and death is only likely when the CD4 count falls below 50 cells per ml when infection is developed with organisms that are di?cult to treat because of their low intrinsic virulence.
Simple, cheap and highly accurate tests are available to detect HIV antibodies in the serum. These normally occur within three months of infection and remain the cornerstone of the diagnosis.
Clinical features Most infected individuals have a viral illness some three weeks after contact with HIV. The clinical features are often non-speci?c and remain undiagnosed but include a ?ne red rash, large lymph nodes, an in?uenza-like illness, cerebral involvement and sometimes the development of opportunistic infections. The antibody test may be negative at this stage but there are usually high levels of virus particles in the blood. The antibody test is virtually always positive within three months of infection. HIV infection is often subsequently asymptomatic for a period of ten years or more, although in most patients progressive immune destruction is occurring during this time and a variety of minor opportunistic infections such as HERPES ZOSTER or oral thrush (see CANDIDA) do occur. In addition, generalised LYMPHADENOPATHY is present in a third of patients and some suffer from severe malaise, weight loss, night sweats, mild fever, ANAEMIA or easy bruising due to THROMBOCYTOPENIA.
The presentation of opportunistic infection is highly variable but usually involves either the CENTRAL NERVOUS SYSTEM, the gastrointestinal tract or the LUNGS. Patients may present with a sudden onset of a neurological de?cit or EPILEPSY due to a sudden onset of a STROKE-like syndrome, or epilepsy due to a space-occupying lesion in the brain – most commonly TOXOPLASMOSIS. In late disease, HIV infection of the central nervous system itself may produce progressive memory loss, impaired concentration and mental slowness called AIDS DEMENTIA. A wide variety of opportunistic PROTOZOA or viruses produces DYSPHAGIA, DIARRHOEA and wasting. In the respiratory system the commonest opportunistic infection associated with AIDS, pneumonia, produces severe shortness of breath and sometimes CYANOSIS, usually with a striking lack of clinical signs in the chest.
In very late HIV infection, when the CD4 count has fallen below 50 cells per ml, infection with CYTOMEGALOVIRUS may produce progressive retinal necrosis (see EYE, DISORDERS OF) which will lead to blindness if untreated, as well as a variety of gastrointestinal symptoms. At this stage, infection with atypical mycobacteria is also common, producing severe anaemia, wasting and fevers. The commonest tumour associated with HIV is Kaposi’s sarcoma which produces purplish skin lesions. This and nonHodgkin’s lymphoma (see LYMPHOMA), which is a hundred times more frequent among HIV-positive individuals than in the general population, are likely to be associated with or caused by opportunistic viral infections.
Prevention There is, as yet, no vaccine to prevent HIV infection. Vaccine development has been hampered
by the large number of new HIV strains generated through frequent mutation and recombination.
because HIV can be transmitted as free virus and in infected cells.
because HIV infects helper T-cells – the very cells involved in the immune response. There are, however, numerous research pro
grammes underway to develop vaccines that are either prophylactic or therapeutic. Vaccine-development strategies have included: recombinant-vector vaccines, in which a live bacterium or virus is genetically modi?ed to carry one or more of the HIV genes; subunit vaccines, consisting of small regions of the HIV genome designed to induce an immune response without infection; modi?ed live HIV, which has had its disease-promoting genes removed; and DNA vaccines – small loops of DNA (plasmids) containing viral genes – that make the host cells produce non-infectious viral proteins which, in turn, trigger an immune response and prime the immune system against future infection with real virus.
In the absence of an e?ective vaccine, preventing exposure remains the chief strategy in reducing the spread of HIV. Used properly, condoms are an extremely e?ective method of preventing exposure to HIV during sexual intercourse and remain the most important public-health approach to countering the further acceleration of the AIDS epidemic. The spermicide nonoxynol-9, which is often included with condoms, is known to kill HIV in vitro; however, its e?ectiveness in preventing HIV infection during intercourse is not known.
Public-health strategies must be focused on avoiding high-risk behaviour and, particularly in developing countries, empowering women to have more control over their lives, both economically and socially. In many of the poorer regions of the world, women are economically dependent on men and refusing sex, or insisting on condom use, even when they know their partners are HIV positive, is not a straightforward option. Poverty also forces many women into the sex industry where they are at greater risk of infection.
Cultural problems in gaining acceptance for universal condom-use by men in some developing countries suggests that other preventive strategies should also be considered. Microbicides used as vaginal sprays or ‘chemical condoms’ have the potential to give women more direct control over their exposure risk, and research is underway to develop suitable products.
Epidemiological studies suggest that male circumcision may o?er some protection against HIV infection, although more research is needed before this can be an established public-health strategy. Globally, about 70 per cent of infected men have acquired the virus through unprotected vaginal sex; in these men, infection is likely to have occurred through the penis with the mucosal epithelia of the inner surface of the foreskin and the frenulum considered the most likely sites for infection. It is suggested that in circumcised men, the glans may become keratinised and thus less likely to facilitate infection. Circumcision may also reduce the risk of lesions caused by other sexually transmitted disease.
Treatment AIDS/HIV treatment can be categorised as speci?c therapies for the individual opportunistic infections – which ultimately cause death – and highly active antiretroviral therapy (HAART) designed to reduce viral load and replication. HAART is also the most e?ective way of preventing opportunistic infections, and has had a signi?cant impact in delaying the onset of AIDS in HIV-positive individuals in developed countries.
Four classes of drugs are currently in use. Nucleoside analogues, including ZIDOVUDINE and DIDANOSINE, interfere with the activity of the unique enzyme of the retrovirus reverse transcriptase which is essential for replication. Nucleotide analogues, such as tenofovir, act in the same way but require no intracellular activation. Non-nucleoside reverse transcriptase inhibitors, such as nevirapine and EFAVIRENZ, act by a di?erent mechanism on the same enzyme. The most potent single agents against HIV are the protease inhibitors, such as lopinavir, which render a unique viral enzyme ineffective. These drugs are used in a variety of combinations in an attempt to reduce the plasma HIV viral load to below detectable limits, which is achieved in approximately 90 per cent of patients who have not previously received therapy. This usually also produces a profound rise in CD4 count. It is likely, however, that such treatments need to be lifelong – and since they are associated with toxicities, long-term adherence is di?cult. Thus the optimum time for treatment intervention remains controversial, with some clinicians believing that this should be governed by the viral load rising above 10,000 copies, and others that it should primarily be designed to prevent the development of opportunistic infections – thus, that initiation of therapy should be guided more by the CD4 count.
It should be noted that the drug regimens have been devised for infection with HIV-1; it is not known how e?ective they are at treating infection with HIV-2.
HIV and pregnancy An HIV-positive woman can transmit the virus to her fetus, with the risk of infection being particularly high during parturition; however, the risk of perinatal HIV transmission can be reduced by antiviral drug therapy. In the UK, HIV testing is available to all women as part of antenatal care. The bene?ts of antenatal HIV testing in countries where antiviral drugs are not available are questionable. An HIV-positive woman might be advised not to breast feed because of the risks of transmitting HIV via breastmilk, but there may be a greater risk associated with not breast feeding at all. Babies in many poor communities are thought to be at high risk of infectious diseases and malnutrition if they are not breast fed and may thus be at greater overall risk of death during infancy.
Counselling Con?dential counselling is an essential part of AIDS management, both in terms of supporting the psychological wellbeing of the individual and in dealing with issues such as family relations, sexual partners and implications for employment (e.g. for health-care workers). Counsellors must be particularly sensitive to culture and lifestyle issues. Counselling is essential both before an HIV test is taken and when the results are revealed.
Health-care workers Health-care workers may be at risk of occupational exposure to HIV, either through undertaking invasive procedures or through accidental exposure to infected blood from a contaminated needle (needlestick injury). Needlestick injuries are frequent in health care – as many as 600,000 to 800,000 are thought to occur annually in the United States. Transmission is much more likely where the worker has been exposed to HIV through a needlestick injury or deep cut with a contaminated instrument than through exposure of mucous membranes to contaminated blood or body ?uids. However, even where exposure occurs through a needlestick injury, the risk of seroconversion is much lower than with a similar exposure to hepatitis C or hepatitis B. A percutaneous exposure to HIV-infected blood in a health-care setting is thought to carry a risk of about one infection per 300 injuries (one in 1,000 for mucous-membrane exposure), compared with one in 30 for hepatitis C, and one in three for hepatitis B (when the source patient is e-antigen positive).
In the event of an injury, health-care workers are advised to report the incident immediately where, depending on a risk assessment, they may be o?ered post-exposure prophylaxis (PEP). They should also wash the contaminated area with soap and water (but without scrubbing) and, if appropriate, encourage bleeding at the site of injury. PEP, using a combination of antiretroviral drugs (in a similar regimen to HAART – see above), is thought to greatly reduce the chances of seroconversion; it should be commenced as soon as possible, preferably within one or two hours of the injury. Although PEP is available, safe systems of work are considered to o?er the greatest protection. Double-gloving (latex gloves remove much of the blood from the surface of the needle during a needlestick), correct use of sharps containers (for used needles and instruments), avoiding the resheathing of used needles, reduction in the number of blood samples taken from a patient, safer-needle devices (such as needles that self-blunt after use) and needleless drug administration are all thought to reduce the risk of exposure to HIV and other blood-borne viruses. Although there have been numerous cases of health-care workers developing HIV through occupational exposure, there is little evidence of health-care workers passing HIV to their patients through normal medical procedures.... aids/hiv
Habitat: Wild in the warm valleys of the outer Himalayas. Cultivated in the plains.
English: Acid or Sour Lime, Country Lime.Ayurvedic: Nimbuka.Unani: Limu Kaghzi.Siddha/Tamil: Elummichhai, Thurinjippazham.Folk: Kaagazi Nimbu.Action: Antiscorbutic, stomachic, appetizer, refrigerant. Used in bilious vomiting. Leaves—an infusion is given for fever in jaundice, for sore throat, thrush. Root—an infusion is given for colic and dysentery, also as febrifuge.
Limes are rich in vitamins, minerals and alkaline salts, but not in fruit sugars. Lime peel contains ergosterol. An enzyme, 1,3-beta-glucan hydrolase has been reported from the bark and leaf extract. See C. limon.... citrus aurantifoliaHabitat: Mishmi Hills in Arunachal Pradesh. Cultivated commercially in China.
Ayurvedic: Mamira, Maamiraa, Tiktamuulaa. (Pita-muulikaa and Hem-tantu are provisional synonyms.)Unani: Maamisaa, Maamiraa.Folk: Titaa (Bengal and Assam).Action: Stomachic, antiperiodic, antibacterial, antifungal. Prescribed in debility, convalescence, intermittent fevers, dyspepsia, dysentery and intestinal catarrh. Used as a local application in thrush.
The rhizomes contains berberine (9%) as the major alkaloid; other alkaloids present are: coptin (0.08%), cop- tisin 0.02%) and jatrorrhizine (0.01%). Samples from China contained 9.2612.23% berberine, 2.39-3.25% coptisin and 3.20-4.46% jatrorrhizine. In China, the herb is used as an antidiabetic; the ethanolic (50%) extract exhibited hypoglycaemic and hypotensive activity.The drug due to berberine and its related alkaloids promoted reticuloen- dothelium to increased phagocytosis of leucocytes in dog blood in vitro and in vivo.Coptis chinensis (Huang Lian) inhibited erythrocyte haemolysis, decreased lipid peroxidation in brain and kidney, decreased generation of superoxide peroxidation and decreased hy- droxyl radicals in rats. (Life Sci, 2000, 66(8), 725-735.)Dosage: Root—1-3 g powder. (CCRAS.)... coptis teetaAdministration of anti-fungals should be accompanied by a sugarless diet. ... anti-fungals
Many modi?cations have been devised of the basic steroid molecule in an attempt to keep useful therapeutic effects and minimise unwanted side-effects. The main corticosteroid hormones currently available are CORTISONE, HYDROCORTISONE, PREDNISONE, PREDNISOLONE, methyl prednisolone, triamcinolone, dexamethasone, betamethasone, paramethasone and de?azacort.
They are used clinically in three quite distinct circumstances. First they constitute replacement therapy where a patient is unable to produce their own steroids – for example, in adrenocortical insu?ciency or hypopituitarism. In this situation the dose is physiological – namely, the equivalent of the normal adrenal output under similar circumstances – and is not associated with any side-effects. Secondly, steroids are used to depress activity of the adrenal cortex in conditions where this is abnormally high or where the adrenal cortex is producing abnormal hormones, as occurs in some hirsute women.
The third application for corticosteroids is in suppressing the manifestations of disease in a wide variety of in?ammatory and allergic conditions, and in reducing antibody production in a number of AUTOIMMUNE DISORDERS. The in?ammatory reaction is normally part of the body’s defence mechanism and is to be encouraged rather than inhibited. However, in the case of those diseases in which the body’s reaction is disproportionate to the o?ending agent, such that it causes unpleasant symptoms or frank illness, the steroid hormones can inhibit this undesirable response. Although the underlying condition is not cured as a result, it may resolve spontaneously. When corticosteroids are used for their anti-in?ammatory properties, the dose is pharmacological; that is, higher – often much higher – than the normal physiological requirement. Indeed, the necessary dose may exceed the normal maximum output of the healthy adrenal gland, which is about 250–300 mg cortisol per day. When doses of this order are used there are inevitable risks and side-effects: a drug-induced CUSHING’S SYNDROME will result.
Corticosteroid treatment of short duration, as in angioneurotic OEDEMA of the larynx or other allergic crises, may at the same time be life-saving and without signi?cant risk (see URTICARIA). Prolonged therapy of such connective-tissue disorders, such as POLYARTERITIS NODOSA with its attendant hazards, is generally accepted because there are no other agents of therapeutic value. Similarly the absence of alternative medical treatment for such conditions as autoimmune haemolytic ANAEMIA establishes steroid therapy as the treatment of choice which few would dispute. The use of steroids in such chronic conditions as RHEUMATOID ARTHRITIS, ASTHMA and DERMATITIS needs careful assessment and monitoring.
Although there is a risk of ill-effects, these should be set against the misery and danger of unrelieved chronic asthma or the incapacity, frustration and psychological trauma of rheumatoid arthritis. Patients should carry cards giving details of their dosage and possible complications.
The incidence and severity of side-effects are related to the dose and duration of treatment. Prolonged daily treatment with 15 mg of prednisolone, or more, will cause hypercortisonism; less than 10 mg prednisolone a day may be tolerated by most patients inde?nitely. Inhaled steroids rarely produce any ill-e?ect apart from a propensity to oral thrush (CANDIDA infection) unless given in excessive doses.
General side-effects may include weight gain, fat distribution of the cushingoid type, ACNE and HIRSUTISM, AMENORRHOEA, striae and increased bruising tendency. The more serious complications which can occur during long-term treatment include HYPERTENSION, oedema, DIABETES MELLITUS, psychosis, infection, DYSPEPSIA and peptic ulceration, gastrointestinal haemorrhage, adrenal suppression, osteoporosis (see BONE, DISORDERS OF), myopathy (see MUSCLES, DISORDERS OF), sodium retention and potassium depletion.... corticosteroids
Diagnosis and treatment Any person with isolated, itching, dry and scaling lesions of the skin with no obvious cause – for example, no history of eczema (see DERMATITIS) – should be suspected of having a fungal infection. Such lesions are usually asymmetrical. Skin scrapings or nail clippings should be sent for laboratory analysis. If the lesions have been treated with topical steroids they may appear untypical. Ultraviolet light ?ltered through glass (Wood’s light) will show up microsporum infections, which produce a green-blue ?uorescence.
Fungal infections used to be treated quite e?ectively with benzoic-acid compound ointment; it has now been superseded by new IMIDAZOLES preparations, such as CLOTRIMAZOLE, MICONAZOLE and terbina?ne creams. The POLYENES, NYSTATIN and AMPHOTERICIN B, are e?ective against yeast infections. If the skin is macerated it can be treated with magenta (Castellani’s) paint or dusting powder to dry it out.
Refractory fungal infection can be treated systematically provided that the diagnosis of the infection has been con?rmed. Terbina?ne, imidazoles and GRISEOFULVIN can all be taken by mouth and are e?ective for yeast infections. (Griseofulvin should not be taken in pregnancy or by people with liver failure or porphyria.) (See also FUNGUS; MICROBIOLOGY.)... fungal and yeast infections
Antifungal preparations are available in various forms including tablets, injection, creams, and pessaries. Prolonged treatment of serious fungal infections can result in side effects that include liver or kidney damage.... antifungal drugs
It is also used as a shampoo to treat dandruff.
Adverse effects include nausea and rash.... ketoconazole
Thrush is characterised by the presence of white patches on the mucous membrane which bleeds if the patch is gently removed. It is caused by the growth of a parasitic mould known as Candida albicans. Antifungal agents usually suppress the growth of candida. Candidal in?ltration of the mucosa is often found in cancerous lesions.
Leukoplakia literally means a white patch. In the mouth it is often due to an area of thickened cells from the horny layer of the epithelium. It appears as a white patch of varying density and is often grooved by dense ?ssures. There are many causes, most of them of minor importance. It may be associated with smoking, SYPHILIS, chronic SEPSIS or trauma from a sharp tooth. Cancer must be excluded.
Stomatitis (in?ammation of the mouth) arises from the same causes as in?ammation elsewhere, but among the main causes are the cutting of teeth in children, sharp or broken teeth, excess alcohol, tobacco smoking and general ill-health. The mucous membrane becomes red, swollen and tender and ulcers may appear. Treatment consists mainly of preventing secondary infection supervening before the stomatitis has resolved. Antiseptic mouthwashes are usually su?cient.
Gingivitis (see TEETH, DISEASES OF) is in?ammation of the gum where it touches the tooth. It is caused by poor oral hygiene and is often associated with the production of calculus or tartar on the teeth. If it is neglected it will proceed to periodontal disease.
Ulcers of the mouth These are usually small and arise from a variety of causes. Aphthous ulcers are the most common; they last about ten days and usually heal without scarring. They may be associated with STRESS or DYSPEPSIA. There is no ideal treatment.
Herpetic ulcers (see HERPES SIMPLEX) are similar but usually there are many ulcers and the patient appears feverish and unwell. This condition is more common in children.
Calculus (a) Salivary: a calculus (stone) may develop in one of the major salivary-gland ducts. This may result in a blockage which will cause the gland to swell and be painful. It usually swells before a meal and then slowly subsides. The stone may be passed but often has to be removed in a minor operation. If the gland behind the calculus becomes infected, then an ABSCESS forms and, if this persists, the removal of the gland may be indicated. (b) Dental, also called TARTAR: this is a calci?ed material which adheres to the teeth; it often starts as the soft debris found on teeth which have not been well cleaned and is called plaque. If not removed, it will gradually destroy the periodontal membrane and result in the loss of the tooth. (See TEETH, DISORDERS OF.)
Ranula This is a cyst-like swelling found in the ?oor of the mouth. It is often caused by mild trauma to the salivary glands with the result that saliva collects in the cyst instead of discharging into the mouth. Surgery may be required.
Mumps is an acute infective disorder of the major salivary glands. It causes painful enlargement of the glands which lasts for about two weeks. (See also main entry for MUMPS.)
Tumours may occur in all parts of the mouth, and may be BENIGN or MALIGNANT. Benign tumours are common and may follow mild trauma or be an exaggerated response to irritation. Polyps are found in the cheeks and on the tongue and become a nuisance as they may be bitten frequently. They are easily excised.
A MUCOCOELE is found mainly in the lower lip.
An exostosis or bone outgrowth is often found in the mid line of the palate and on the inside of the mandible (bone of the lower jaw). This only requires removal if it becomes unduly large or pointed and easily ulcerated.
Malignant tumours within the mouth are often large before they are noticed, whereas those on the lips are usually seen early and are more easily treated. The cancer may arise from any of the tissues found in the mouth including epithelium, bone, salivary tissue and tooth-forming tissue remnants. Oral cancers represent about 5 per cent of all reported malignancies, and in England and Wales around 3,300 people are diagnosed annually as having cancer of the mouth and PHARYNX.
Cancer of the mouth is less common below the age of 40 years and is more common in men. It is often associated with chronic irritation from a broken tooth or ill-?tting denture. It is also more common in those who smoke and those who chew betel leaves. Leukoplakia (see above) may be a precursor of cancer. Spread of the cancer is by way of the lymph nodes in the neck. Early treatment by surgery, radiotherapy or chemotherapy will often be e?ective, except for the posterior of the tongue where the prognosis is very poor. Although surgery may be extensive and potentially mutilating, recent advances in repairing defects and grafting tissues from elsewhere have made treatment more acceptable to the patient.... mouth, diseases of
Miconazole in the form of a cream or vaginal suppository may, in rare cases, cause a burning sensation or a rash.... miconazole
Beams of radiation may be directed at the tumour from a distance, or radioactive material
– in the form of needles, wires or pellets – may be implanted in the body. Sometimes germ-cell tumours (see SEMINOMA; TERATOMA) and lymphomas (see LYMPHOMA) are particularly sensitive to irradiation which therefore forms a major part of management, particularly for localised disease. Many head and neck tumours, gynaecological cancers, and localised prostate and bladder cancers are curable with radiotherapy. Radiotherapy is also valuable in PALLIATIVE CARE, chie?y the reduction of pain from bone metastases (see METASTASIS). Side-effects are potentially hazardous and these have to be balanced against the substantial potential bene?ts. Depending upon the type of therapy and doses used, generalised effects include lethargy and loss of appetite, while localised effects – depending on the area treated – include dry, itchy skin; oral infection (e.g. thrush – see CANDIDA); bowel problems; and DYSURIA.... radiotherapy
Habitat: Native to the Mediterranean region; grown as an ornamental.
English: Sage.Folk: Salvia Sefakuss.Action: Plant—astringent, anti- inflammatory, carminative, anti- spasmodic, antiseptic. Leaf and flower—cholagogue, hypogly- caemic, antiasthmatic (used for respiratory allergy), cholagogue, emmenagogue, antisudoriferous, antiseptic. Leaf—diaphoretic, antipyretic. Used for sore throat, laryngitis, tonsillitis, stomatitis.
Key application: Leaf—internally, for dyspeptic symptoms and excessive perspiration; externally for inflammations of the mucous membranes of nose and throat. (German Commission E.) ESCOP indicates its use for inflammations and infections such as stomatitis, gingivitis, pharyngitis, and hyperhidrosis.The leaves contain a volatile oil; diterpene bitters including carnosolic acid; flavonoids including salvigenin, genkwanin, hispidulin, luteolin and its derivatives; phenolic acids including rosmarinic, caffeic, labiatic; a condensed catechin, salvia tannin.The roots contain diterpene quino- nesroyleanone and its derivatives. Volatile oil contains alpha-and beta-thu- jone, 1,8-cineole and camphor. Thu- jone is strongly antiseptic and carminative, also has an oestrogenic action that is partly responsible for the herb's hormonal activity in reducing breast milk production. The volatile oil also relieves muscle spasms. Ros- marinic acid, a phenol, allays inflammations.Cirsiliol, linalool and alpha-terpine- ol, constituents of the volatile oil, exhibit CNS depressant activities.In a double blind, randomized and placebo controlled trial, extracts of Salvia officinalis showed improvement in patients with mild to moderate Alzheimer disease. (Natural Medicines Comprehensive Database, 2007.)Sage oil is used in perfumes as a deodorant and for the treatment of thrush and gingivitis. The herb is used in tooth powders, mouth washes, gargles, poultices, hair tonics and hair dressings.... salvia officinalisHabitat: The temperate Himalayas from Kashmir eastwards and in Khasi Hills, up to 3,000 m.
English: European Goldenrod, Woundwort.Action: Anticatarrhal, diaphoretic, anti-inflammatory, antiseptic to mucous membranes.
Key application: In irrigation therapy for inflammatory diseases of the lower urinary tract, urinary calculi and kidney gravel. (German Commission E.) ESCOP also indicates its use as an adjuvant in the treatment of bacterial infections of the urinary tract.Anti-inflammatory activity is due to phenolic glycosides; antifungal activity is due to saponins based on polygalic acid (acts specifically against the candida fungus, the cause of vaginal and oral thrush). As a diuretic, aerial parts are used for nephritis and cystitis and to flush out kidney and bladder stones; urine volume is increased but not sodium excretion.The plant contains quercitrin, rutin, iso-quercitrin, astragalin, kaempfer- ol, rhamnoglucoside, quercetin, caffeic acid and chlorogenic acid. Aerial parts contain diterpenoids of cis-clerodane lactone group.... solidago virga-aureaHabitat: Cultivated in Bengal and South India, chiefly in gardens.
English: Malay Apple, Mountain Apple.Action: Leaves—dried and powdered, used against stomatitis. Bark—astringent; used for making a mouthwash for thrush.
The extracts of seeds, fruits, leaves, stem and bark show varying degree of antibiotic activity against Micrococcus pyogenes var. aureus. An extract of fruits (without seeds) is moderately effective against E. coli and those of bark and leaves against Shigella paradys.The extracts of the plant, excluding root, affect the rate and amplitude of respiration and also blood pressure.... syzygium malaccenseL.A. is available in tablets and capsules. As a vaginal douche the powder can be used for thrush. It is necessary to follow the use of antibiotics of orthodox pharmacy. Of value for Candida albicans, allergies, depression and some forms of menstrual disorders. ... acidophilus
Dried or fresh leaves and flowers.
Constituents: phenolic glycosides, saponins, rutin.
Action: anticatarrhal, anti-inflammatory, antiseptic to mucous membranes, diuretic, diaphoretic.
Uses: Weak stomach, nausea, vomiting, hiccups, persistent catarrh of nose and throat. Thrush and sore throat (gargle). Irritable bowel in children. Bronchitis, with purulent phlegm. Blood in the urine. Tonsilitis, with pus. Reduces mass in kidney stone and gravel (anecdotal). Prostatis. Kidney and bladder conditions where urine is dark, scanty and reddish brown.
Dr Gallavardin cured her husband of kidney trouble after he was compelled to use a catheter for over a year, by giving him tea made from the dried leaves and flowers, morning and evening.
Preparations: Standard dose: half-2 grams. Thrice daily.
Tea. Half-1 teaspoon to each cup boiling water; infuse 15 minutes. Dose: 1 cup.
Liquid Extract. Dose, half-2ml.
Tincture BHP (1983) 1:5 in 45 per cent alcohol. Dose: 0.5 to 1ml. Compress (cold), for wounds and ulcers. ... goldenrod
Symptoms: redness, soreness, itching followed by blisters on the penis or vulva. Blisters ulcerate before crusting over. Lesions on anus of homosexual men.
Treatment by general medical practitioner or hospital specialist.
Alternatives. Sarsaparilla, Echinacea, Chaparral and St John’s Wort often give dramatic relief to itching rash. See entry: ECHINACEA.
Tea. Formula. Equal parts: Clivers, Gotu Kola, Valerian. One heaped teaspoon to each cup boiling water; infuse 5-10 minutes. Dose: 1 cup thrice daily.
Decoction. Combine: Echinacea 2; Valerian 1; Jamaican Dogwood 1. One heaped teaspoon to each cup water gently simmered 20 minutes. Half-1 cup thrice daily.
Tablets/capsules. Poke root. Valerian. Passion flower. St John’s Wort. Echinacea. Chaparral. Pulsatilla. Red Clover.
Powders. Formula. Echinacea 2; Valerian 1; Jamaica Dogwood 1. Dose: 500mg (two 00 capsules or one- third teaspoon) thrice daily.
Tinctures. Formula. Echinacea 2; Sarsaparilla 1; Thuja quarter; Liquorice quarter. Dose: 1-2 teaspoons thrice daily.
Topical. Apply any of the following 3, 4 or more times daily. Pulp or gel of Aloe Vera, Houseleek, Echinacea lotion. Garlic – apply slice of fresh corm as an antihistamine. Yoghurt compresses (improved by pinch of Goldenseal powder). Zinc and Castor oil (impressive record). Apply direct or on tampons. Diet. Porridge oats, or muesli oats.
Supplementation: same as for Shingles.
Prevention. Women should be advised to submit for an annual cytosmear. Information. Herpes Association, 41 North Road, London N7 9DP, UK. Send SAE. ... herpes, genital
Most of the commonly used antibiotic drugs belong to one of the following classes: penicillins, quinolones, aminoglycosides, cephalosporins, macrolides, and tetracyclines. Some antibiotics are effective against only certain types of bacteria; others, which are known as broad-spectrum antibiotics, are effective against a wide range.
Some bacteria develop resistance to a previously effective antibiotic drug. This is most likely to occur during long-term treatment. Some alternative antibiotics are available to treat bacteria that have become resistant to the more commonly prescribed drugs.
Most antibiotic drugs can cause nausea, diarrhoea, or a rash. Antibiotics may disturb the normal balance between certain types of bacteria and fungi in the body, leading to proliferation of the fungi that cause candidiasis (thrush). Some people experience a severe allergic reaction to the drugs, resulting in facial swelling, itching, or breathing difficulty.... antibiotic drugs
Fungal infections are therefore more common and serious in people taking long-term antibiotic drugs (which destroy the bacterial competition) and in those whose immune systems are suppressed by immunosuppressant drugs, corticosteroid drugs, or by a disorder such as AIDS. Such serious fungal infections are described as opportunistic infections. Some fungal infections are more common in people with diabetes mellitus.
Fungal infections can be classified into superficial (affecting skin, hair, nails, inside of the mouth, and genital organs); subcutaneous (beneath the skin); and deep (affecting internal organs).
The main superficial infections are tinea (including ringworm and athlete’s foot) and candidiasis (thrush), both of which are common. Subcutaneous infections, which are rare, include sporotrichosis and mycetoma. Deep infections are uncommon but can be serious and include aspergillosis, histoplasmosis, cryptococcosis, and blastomycosis. The fungal spores enter the body by inhalation.
Treatment of fungal infections is with antifungal drugs, either used topically on the infected area or given by mouth for generalized infections.... fungal infections
Congenital or inherited deficiencies can occur in either of the 2 prongs of the adaptive immune system: humoral or cellular. Deficiencies of the humoral system include hypogammaglobulinaemia and agammaglobulinaemia. The former may cause few or no symptoms, depending on the severity of the deficiency, but agammaglobulinaemia can be fatal if not treated with immunoglobulin. Congenital deficiencies of T-lymphocytes may lead to problems such as persistent and widespread candidiasis (thrush). A combined deficiency of both humoral and cellular components of the immune system, called severe combined immunodeficiency (SCID), is usually fatal in the 1st year of life unless treatment can be given by bone marrow transplant.
Acquired immunodeficiency may be due either to disease processes (such as infection with HIV, which leads to AIDS) or damage to the immune system as a result of its suppression by drugs. Severe malnutrition and many cancers can also cause immunodeficiency. Mild immunodeficiency arises through a natural decline in immune defences with age.... immunodeficiency disorders
oat cell carcinoma A form of lung cancer, also known as small cell carcinoma. obesity A condition in which excess fat has accumulated in the body. A person 20 per cent above the recommended weight for his or her height (see weight) is obese rather than overweight. About 2 in 5 people in the are overweight and a further 1 in 5 obese.
Obesity is usually caused by consuming more food than is needed for energy. Energy requirements are determined by metabolic rate (see metabolism) and level of physical activity. Family history is sometimes a factor. Obesity is associated with some hormonal disorders, but these are not generally the cause.
Obesity increases the risk of hypertension, stroke, and diabetes mellitus type 2. Coronary artery disease is more common, particularly in obese men under 40. Obesity in men is also associated with increased risk of cancer of the colon, rectum, and prostate, and, in women, of the breast, uterus, and cervix. Extra weight may aggravate osteoarthritis.
The first line of treatment is a slimming diet (see weight reduction) plus regular exercise.
Drugs such as appetite suppressants are rarely used due to their side effects.
Wiring of the jaws, stapling of the stomach, and intestinal bypass operations are attempted only if obesity is endangering a person’s health.... nystatin
Keynote: injuries. Not the same plant as French Marigold (Tagetes patula).
Constituents: volatile oil, flavonoids, triterpenes.
Action: immune stimulant, anti-protazoal, anti-inflammatory, anti-fungal, anti-spasmodic, anti- haemorrhage, anti-histamine, anti-bacterial effect particularly against staphylococcus and streptococcus, anti-emetic, anti-cancer, antiseptic, styptic, haemostatic, diaphoretic, anthelmintic, oestrogenic activity (extract from fresh flowers), menstrual regulator.
Uses: Internal. A remedy which should follow all surgical operations. Enlarged and inflamed lymphatic glands, gastric and duodenal ulcer, jaundice, gall bladder inflammation, absent or painful menstruation, balanitis, rectum – inflammation of, gum disease, nose-bleeds, sebaceous cysts, measles (cup of tea drunk freely), pneumonia – a cooling drink which is anti-inflammatory. Vaginal thrush.
Uses: External. Rapid epithelisation process in damaged skin tissue, especially alcoholic extract; rapid wound adhesion and granulation without suppuration. (Weleda)
Wounds where the skin has been broken: laceration with bleeding (Arnica for unbroken skin). Sores, leg ulcers, abscess etc. Sore nipples in nursing mothers, varicose veins, nosebleeds, grazed knees in schoolchildren. Bee, wasp and other insect stings. Chilblains, fistula, inflamed nails, whitlow, dry chapped skin and lips, wind burn, air pollution.
Dentistry: Tooth extractions: rinse mouth with infusion of the florets or much-diluted tincture – 5-10 drops in water.
Malignancy: strong tea, 1-2oz to 1 pint boiling water; use as a wash to cleanse exudations.
STD purulent discharge: inject douche of strong infusion as above.
Wm M. Gregory MD, Berea, Ohio, USA. “I have never seen one drop of pus develop in any wound, however dirty.”
Preparations: For internal or external use. Average dose, 1-4 grams, or equivalent. Thrice daily.
Tea: dried petals/florets. 1-2 teaspoons to each cup boiling water; infuse 15 minutes. Drink freely.
Home tincture. 1 handful petals/florets (approximately 50g) to 1 pint (500ml) 70 per cent alcohol (Vodka); stand 14 days in a warm place, shake daily. Filter. Dose: 5-20 drops in water.
Poultice. Handful petals/florets to 1 pint boiling water; infuse 15 minutes. Apply on suitable material to injuries where skin is broken; replenish when dry.
Herbalist’s Friend. 1 part Tincture Calendula to 4 parts Witch Hazel, for phlebitis and painful varicose veins.
Weleda. Calendula lotion locally, or as a mouth wash and gargle. ... marigold
Infections of the oesophagus are rare but may occur in immunosuppressed patients. The most common are herpes simplex and candidiasis (thrush). Oesophagitis is usually due to reflux of stomach contents, causing heartburn. Corrosive oesophagitis can occur as a result of swallowing caustic chemicals. Both may cause an oesophageal stricture.
Congenital defects include oesophageal atresia, which requires surgery soon after birth. Tumours of the oesophagus are quite common; about 90 per cent are cancerous (see oesophagus, cancer of). Injury to the oesophagus is most commonly caused by a tear or rupture due to severe vomiting and retching. (See also swallowing difficulty.)... oesophagus, disorders of
The most common cause, especially in women, is cystitis. Other causes include a bladder tumour, bladder stone (see calculus, urinary tract), urethritis, balanitis, prostatitis, vaginal candidiasis (thrush), or allergy to vaginal deodorants. Strangury is usually caused by spasm of an inflamed bladder wall, but it may be due to bladder stones. Mild discomfort when passing urine may be caused by highly concentrated urine.
Dysuria may be investigated by physical examination, urinalysis, urography, or cystoscopy. (See also urethral syndrome, acute.)... urination, painful
FAMILY: Myrtaceae
SYNONYMS: Narrow-leaved paperbark tea tree, ti-tree, ti-trol, melasol.
GENERAL DESCRIPTION: A small tree or shrub (smallest of the tea tree family), with needle-like leaves similar to cypress, with heads of sessile yellow or purplish flowers.
DISTRIBUTION: Native to Australia. Other varieties have been cultivated elsewhere, but M. alternifolia is not produced outside Australia, mainly in New South Wales.
OTHER SPECIES: Tea tree is a general name for members of the Melaleuca family which exists in many physiological forms including cajeput (M. cajeputi) and niaouli (M. viridiflora), and many others such as M. bracteata and M. linariifolia – see Botanical Classification section.
HERBAL/FOLK TRADITION: The name derives from its local usage as a type of herbal tea, prepared from the leaves. Our present knowledge of the properties and uses of tea tree is based on a very long history of use by the aboriginal people of Australia. It has been extensively researched recently by scientific methods with the following results: ‘1. This oil is unusual in that it is active against all three varieties of infectious organisms: bacteria, fungi and viruses. 2. It is a very powerful immuno-stimulant, so when the body is threatened by any of these organisms ti-tree increases its ability to respond.’ .
ACTIONS: Anti-infectious, anti-inflammatory, antiseptic, antiviral, bactericidal, balsamic, cicatrisant, diaphoretic, expectorant, fungicidal, immuno-stimulant, parasiticide, vulnerary.
EXTRACTION: Essential oil by steam or water distillation from the leaves and twigs.
CHARACTERISTICS: A pale yellowy-green or water-white mobile liquid with a warm, fresh, spicy-camphoraceous odour. It blends well with lavandin, lavender, clary sage, rosemary, oakmoss, pine, cananga, geranium, marjoram, and spice oils, especially clove and nutmeg.
PRINCIPAL CONSTITUENTS: Terpinene-4-ol (up to 30 per cent), cineol, pinene, terpinenes, cymene, sesquiterpenes, sesquiterpene alcohols, among others.
SAFETY DATA: Non-toxic, non-irritant, possible sensitization in some individuals.
AROMATHERAPY/HOME: USE
Skin care: Abscess, acne, athlete’s foot, blisters, burns, cold sores, dandruff, herpes, insect bites, oily skin, rashes (nappy rash), spots, verrucae, warts, wounds (infected).
Respiratory system: Asthma, bronchitis, catarrh, coughs, sinusitis, tuberculosis, whooping cough.
Genito-urinary system: Thrush, vaginitis, cystitis, pruritis.
Immune system: Colds, fever, ’flu, infectious illnesses such as chickenpox.
OTHER USES: Employed in soaps, toothpastes, deodorants, disinfectants, gargles, germicides and, increasingly, in aftershaves and spicy colognes.... tea tree
FAMILY: Rutaceae
SYNONYM: Citrus aurantium subsp. bergamia.
GENERAL DESCRIPTION: A small tree, about 4.5 metres high with smooth oval leaves, bearing small round fruit which ripen from green to yellow, much like a miniature orange in appearance.
DISTRIBUTION: Native to tropical Asia. Extensively cultivated in Calabria in southern Italy and also grown commercially on the Ivory Coast.
OTHER SPECIES: Not to be confused with the herb bergamot or bee balm (Monarda didyma).
HERBAL/FOLK TRADITION: Named after the Italian city of Bergamo in Lombardy, where the oil was first sold. The oil has been used in Italian folk medicine for many years, primarily for fever (including malaria) and worms; it does not feature in the folk tradition of any other countries. However, due to recent research in Italy, bergamot oil is now known to have a wide spectrum of applications, being particularly useful for mouth, skin, respiratory and urinary tract infections.
ACTIONS: Analgesic, anthelmintic, antidepressant, antiseptic (pulmonary, genito-urinary), antispasmodic, antitoxic, carminative, digestive, diuretic, deodorant, febrifuge, laxative, parasiticide, rubefacient, stimulant, stomachic, tonic, vermifuge, vulnerary.
EXTRACTION: Essential oil by cold expression of the peel of the nearly ripe fruit. (A rectified or terpeneless oil is produced by vacuum distillation or solvent extraction.)
CHARACTERISTICS: A light greenish-yellow liquid with a fresh sweet-fruity, slightly spicy-balsamic undertone. On ageing it turns a brownish-olive colour. It blends well with lavender, neroli, jasmine, cypress, geranium, lemon, chamomile, juniper, coriander and violet.
PRINCIPAL CONSTTTUENTS Known to have about 300 compounds present in the expressed oil: mainly linalyl acetate (30–60 per cent), linalol (11–22 per cent) and other alcohols, sesquiterpenes, terpenes, alkanes and furocoumarins (including bergapten, 0.30–0.39 per cent).
SAFETY DATA: Certain furocoumarins, notably bergapten, have been found to be phototoxic on human skin; that is, they cause sensitization and skin pigmentation when exposed to direct sunlight (in concentration and in dilution even after some time!). Extreme care must be taken when using the oil in dermal applications – otherwise a rectified or ‘bergapten-free’ oil should be substituted. Available information indicates it to be otherwise non-toxic and relatively non-irritant.
AROMATHERAPY/HOME: USE
Skin Care: Acne, boils, cold sores, eczema, insect repellent and insect bites, oily complexion, psoriasis, scabies, spots, varicose ulcers, wounds.
Respiratory System: Halitosis, mouth infections, sore throat, tonsillitis.
Digestive System: Flatulence, loss of appetite.
Genito-URINARY SYSTEM: Cystitis, leucorrhoea, pruritis, thrush.
Immune System: Colds, fever, ’flu, infectious diseases.
Nervous System: Anxiety, depression and stress-related conditions, having a refreshing and uplifting quality.
OTHER USES: Extensively used as a fragrance and, to a degree, a fixative in cosmetics, toiletries, suntan lotions and perfumes – it is a classic ingredient of eau-de-cologne. Widely used in most major food categories and beverages, notably Earl Grey tea.... bergamot
FAMILY: Myrtaceae
SYNONYMS: Taxandria fragrans, coarse tea-tree.
GENERAL DESCRIPTION: Agonis is a genus comprising four species, all of which are native to Western Australia. The species generally have fibrous, brown bark, dull green leaves and inflorescences of small, white flowers. They are best known and most readily identified by the powerful peppermint or eucalyptus-like odour emitted when the leaves are crushed or torn. A. fragrans is a small shrub which grows up to 2.5 metres high, with narrow leaves and clusters of small white flowers, characteristic of the genus.
DISTRIBUTION: As a wild native species, fragonia (A. fragrans) has limited distribution in Western Australia, growing near the coast in the south-west region and being reliant on its winter rains and drier summers. For commercial purposes, A. fragrans is grown in large plantations in south-western Australia.
OTHER SPECIES: The Myrtaceae is a large family of plants with over 3,000 species. It is one of the most important families from an aromatherapy perspective, as it includes not only members of the Agonis genus (which includes trees such as A. flexuosa, the Western Australian peppermint) but also hundreds of aromatic plants from the Eucalyptus, Leptospermum, Melaleuca, Myrtus and Pimenta genera. There are several varying chemotypes of A. fragrans, but fragonia essential oil has a unique balance of primary constituents, which imparts its particular therapeutic qualities.
HERBAL/FOLK TRADITION: The name Agonis derives from the Greek agon, meaning ‘gathering’ or ‘collection’, in reference to the tightly clustered flowers. Traditional knowledge on A. fragrans has never been recorded, and there is no known use of the plant by early settlers. The species only came to the forefront at around the turn of the century when a husband-and-wife team heard about the local plant and began to explore its potential. Having selected superior genetic varieties, they established a small plantation of these shrubs on their property in south-west Western Australia in 2001. The essential oil distilled from this specific plant and chemotype is thus relatively new to the aromatherapy industry. Indeed it has only recently been given its common name ‘fragonia’ by its discoverer Chris Robinson, and has since been trademarked as FragoniaTM. In a series of tests, the University of Western Australia demonstrated that fragonia oil has anti-inflammatory properties and significant anti-microbial activity, similar to tea tree oil.
ACTIONS: Analgesic (mild), antibacterial, anti-inflammatory, antifungal, antimicrobial, anti-infectious, antiseptic, expectorant, immuno-tonic, nervine, regulating.
EXTRACTION: An essential oil by steam distillation from the stems, twigs and leaves.
CHARACTERISTICS: A pale, watery liquid with a pleasant slightly citrus, fresh-clean and faintly medicinal top note, mixed with a slight spicy, earthy and balsamic undertone: more pleasing than tea tree. It blends well with niaouli, eucalyptus, myrtle, lemon myrtle, rosemary and tea tree.
PRINCIPAL CONSTITUENTS: Primary constituents are 1,8-cineole, alpha-pinene and linalool. From a chemical perspective, it is an extremely well-balanced oil, with the oxides (1,8-cineole), monoterpenes (alpha-pinene) and monoterpenols (linalool, geraniol, terpineol and others) in a near perfect 1:1:1 ratio.
SAFETY DATA: Fragonia essential oil is non-toxic, non-irritant and non-sensitizing: an extremely mild oil when applied to the skin and safe for children.
AROMATHERAPY/HOME: USE:
Skin Care: Cuts, bites, stings and general skin care.
Circulation Muscles And Joints: Aching muscles and joints, arthritis, rheumatism.
Respiratory System: Asthma, bronchitis, coughs, colds, influenza, sinusitis, tonsillitis.
Genito-Urinary System: Candida (thrush), menstrual pain and breast tenderness, vaginitis.
Immune System: Powerful immune-system tonic and restorative.
Nervous System: Anxiety, depression, emotional blockages, grief, insomnia, nervous debility and tension, mood swings, stress.
OTHER USES: Many Agonis species are used as decorative garden plants while sprigs of the white flowers of A. fragrans are cut and used in the florist industry. Fragonia oil is now being used in the phyto-cosmetic industry, e.g. for soaps and skin care products. The oil can also be used as a natural, fresh-smelling disinfectant around the home, e.g. as a room fragrance, in the laundry and for cleaning bathroom and kitchen surfaces.... fragonia
Amenorrhoea/lack of menstruation (M,B):
French basil, carrot seed, celery seed, cinnamon leaf, dill, sweet fennel, hops, hyssop, juniper, laurel, lovage, sweet marjoram, myrrh, parsley, rose (cabbage & damask), sage (clary & Spanish), tarragon, yarrow.
Dysmenorrhoea/cramp, painful or difficult menstruation (M,C,B):
Melissa, French basil, carrot seed, chamomile (German & Roman), cypress, frankincense, hops, jasmine, juniper, lavandin, lavender (spike & true), lovage, sweet marjoram, rose (cabbage & damask), rosemary, sage (clary & Spanish), tarragon, yarrow.
Cystitis (C,B,D):
Canadian balsam, copaiba balsam, bergamot, cedarwood (Atlas, Texas & Virginian), celery seed, chamomile (German & Roman), cubebs, eucalyptus blue gum, frankincense, juniper, lavandin, lavender (spike & true), lovage, mastic, niaouli, parsley, Scotch pine, sandalwood, tea tree, thyme, turpentine, yarrow.
Frigidity (M,S,B,V):
Cassie, cinnamon leaf, jasmine, neroli, nutmeg, parsley, patchouli, black pepper, cabbage rose, rosewood, clary sage, sandalwood, ylang ylang.
Lack of nursing milk (M):
Celery seed, dill, sweet fennel, hops.
Labour pain & childbirth aid (M,C,B):
Cinnamon leaf, jasmine, true lavender, nutmeg, parsley, rose (cabbage & damask), clary sage.
Leucorrhoea/white discharge from the vagina (B,D):
Bergamot, cedarwood (Atlas, Texas & Virginian), cinnamon leaf, cubebs, eucalyptus blue gum, frankincense, hyssop, lavandin, lavender (spike & true), sweet marjoram, mastic, myrrh, rosemary, clary sage, sandalwood, tea tree, turpentine.
Menopausal problems (M,B,V):
Cypress, sweet fennel, geranium, jasmine, rose (cabbage & damask).
Menorrhagia/excessive menstruation (M,B):
Chamomile (German & Roman), cypress, rose (cabbage & damask).
Premenstrual tension/PMT (M,B,V):
Carrot seed, chamomile (German & Roman), geranium, true lavender, sweet marjoram, neroli, tarragon.
Pruritis/itching (D):
Bergamot, Atlas cedarwood, juniper, lavender, myrrh, tea tree.
Sexual overactivity (M,B):
Hops, sweet marjoram.
Thrush/candida (B,D):
Bergamot, geranium, myrrh, tea tree.
Urethritis (B,D):
Bergamot, cubebs, mastic, tea tree, turpentine.
Immune System
Chickenpox (C,S,B):
Bergamot, chamomile (German & Roman), eucalyptus (blue gum & lemon), true lavender, tea tree.
Colds/’flu (M,B,V,I):
Angelica, star anise, aniseed, copaiba balsam, Peru balsam, French basil, West Indian bay, bergamot, borneol, cabreuva, cajeput, camphor (white), caraway, cinnamon leaf, citronella, clove bud, coriander, eucalyptus (blue gum, lemon & peppermint), silver fir, frankincense, ginger, grapefruit, immortelle, juniper, laurel, lemon, lime, sweet marjoram, mastic, mint (peppermint & spearmint), myrtle, niaouli, orange (bitter & sweet), pine (longleaf & Scotch), rosemary, rosewood, Spanish sage, hemlock spruce, tea tree, thyme, turpentine, yarrow.
Fever (C,B):
French basil, bergamot, borneol, camphor (white), eucalyptus (blue gum, lemon & peppermint), silver fir, ginger, immortelle, juniper, lemon, lemongrass, lime, mint (peppermint & spearmint), myrtle, niaouli, rosemary, rosewood, Spanish sage, hemlock spruce, tea tree, thyme, yarrow.
Measles (S,B,I,V):
Bergamot, eucalyptus blue gum, lavender (spike & true), tea tree.... genito-urinary and endocrine systems