Thyro: From 1 Different Sources
combining form denoting the thyroid gland. Example: thyroglossal (relating to the thyroid gland and tongue).
A pathologic thyroid hyperfunction. It is sometimes referred to as exophthalmic goiter. An overt disease, sometimes life-threatening, it is very different from the moderately elevated basal metabolism some constitutional types manifest under stress.... thyrotoxicosis
A rare disease that accounts for around 1 per cent of all cancers, cancer of the THYROID GLAND usually presents as an isolated hard nodule in the neck. The rate at which the nodule grows depends upon the patient’s age and type of cancer cell. Pain is not usually a feature, but the increasing size may result in the tumour pressing on vital structures in the neck – for example, the nerves controlling the LARYNX (resulting in hoarseness) and the PHARYNX (causing di?culty in swallowing). If more than one nodule is present, they are likely to be benign, not malignant. Treatment is by surgical removal after which the patient will need to take THYROXINE for the rest of his or her life. Radioactive iodine is usually given after surgery to destroy any residual cancerous cells. If treated early, the outlook is good.... thyroid cancer
Surgical removal of the THYROID GLAND. Partial thyroidectomy – removal of part of the gland – is sometimes done in patients with hyperthyroidism (see under THYROID GLAND, DISEASES OF) when drug treatment has failed to control the disorder.... thyroidectomy
See under THYROID GLAND, DISEASES OF.... thyroiditis
The iodine-containing protein that is stored in the thyroid gland. It is converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary (in turn stimulated by the hypothalamus, where thyroxine levels are actually monitored). See: T4... thyroglobulin
The largest cartilage in the LARYNX and forms the prominence of the Adam’s apple in front of the neck.... thyroid cartilage
... thyroid gland, diseases of
A hormone (see HORMONES) produced and released by the HYPOTHALAMUS which stimulates the release of THYROTROPHINSTIMULATING HORMONE (TSH) by the PITUITARY GLAND.... thyrotrophin-releasing hormone (trh)
A hormone (see HORMONES) manufactured and released by the anterior part of the PITUITARY GLAND which stimulates the THYROID GLAND to manufacture and release thyroid hormones (THYROXINE and TRI-IODOTHYRONINE).... thyrotrophin-stimulating hormone (tsh)
A set of congenital defects caused by failure of the thyroglossal duct to disappear during embryonic development. In embryos, this duct runs from the base of the tongue to the thyroid gland. Abnormal development may cause the duct to persist in its entirety or partly as a cyst. A cyst usually becomes infected and swollen, which may lead to formation of a fistula. The cyst and any remaining parts of the duct are removed.... thyroglossal disorders
A group of blood tests used to evaluate the function of the thyroid gland and to detect or confirm any thyroid disorder. The thyroid hormones T3 and T4 are measured, as well as thyroid-stimulating hormone (TSH), the pituitary gland hormone that stimulates the thyroid gland.... thyroid-function tests
Techniques, such as radionuclide scanning and ultrasound scanning, that are used to provide information about the location, anatomy, and function of the thyroid gland.... thyroid scanning
n. see calcitonin.... thyrocalcitonin
n. a swelling of the thyroid gland. See goitre.... thyrocele
adj. relating to the thyroid cartilage and hyoid bone. The thyrohyoid ligaments form part of the *larynx; contraction of the thyrohyoid muscle raises the larynx.... thyrohyoid
a rarely seen but well-documented alteration in the shape of the nails resembling *clubbing but unique to Graves’ disease (see thyrotoxicosis). It is often associated with formation of new bone seen on X-rays of the hands and wrists, which is said to resemble bubbles along the surface of the bones.... thyroid acropachy
autoantibodies directed against the cells of the thyroid gland, which serve as a marker of autoimmune thyroid disease. There are two main types: antibodies directed against the thyroid peroxidise (TPO) enzyme; and anti-thyroglobulin, directed against the thyroid colloid (see thyroid gland). The highest level of thyroid antibodies is found in *Hashimoto’s disease.... thyroid antibodies
(thyroid storm) a life-threatening condition due to an acute and severe exacerbation of previously undiagnosed or inadequately treated *thyrotoxicosis. It often follows infections, childbirth, nonthyroid surgery, or trauma but can occur without an obvious cause. The presenting features are a fever, severe agitation, nausea and vomiting, diarrhoea, and abdominal pains. An accelerated heart rate and irregularity of the heart rhythm can cause heart failure, and psychotic episodes or coma can result. Blood tests will reveal hyperthyroidism and may also show altered liver function, high blood sugar, high calcium levels, a high white blood cell count, and often anaemia. Treatment is with intravenous fluids, oxygen, antithyroid drugs (such as *carbimazole or *propylthiouracil), high-dose iodide solution (see Lugol’s solution), high-dose steroids, and beta blockers. The patient must be cooled and given antipyretics, such as paracetamol. Any underlying cause must also be treated.... thyroid crisis
an iodine-containing substance, synthesized and secreted by the thyroid gland, that is essential for normal metabolic processes and mental and physical development. There are two thyroid hormones, *triiodothyronine and *thyroxine, which are formed from *thyroglobulin. Lack of these hormones gives rise to *cretinism in infants and *myxoedema in adults. Excessive production of thyroid hormones gives rise to *thyrotoxicosis.... thyroid hormone
(TSH, thyrotrophin) a hormone, synthesized and secreted by the anterior pituitary gland under the control of *thyrotrophin-releasing hormone, that stimulates activity of the thyroid gland. Raised levels of TSH are found in primary *hypothyroidism. Normal or low TSH levels in the presence of a low serum thyroxine are found in secondary hypothyroidism and the *euthyroid sick syndrome.... thyroid-stimulating hormone
see thyroid crisis.... thyroid storm
n. a surgical procedure performed on the thyroid cartilage of the larynx to alter the characteristics of the voice.... thyroplasty
n. surgical incision of either the thyroid cartilage in the neck or of the thyroid gland itself.... thyrotomy
a condition in which attacks of sudden weakness and flaccidity occur in patients with *thyrotoxicosis, seen most often in males of Asian descent. The attacks last from hours to days; they can be prevented by potassium supplements and subsequent treatment of the thyrotoxicosis.... thyrotoxic periodic paralysis
n. see thyroid-stimulating hormone.... thyrotrophin
(TRH) a hormone from the hypothalamus (in the brain) that acts on the anterior pituitary gland to stimulate the release of *thyroid-stimulating hormone. A preparation of TRH (protirelin) may be given by intravenous injection to test thyroid gland function and to estimate reserves of thyroid-stimulating hormone in the pituitary.... thyrotrophin-releasing hormone
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