Tiabendazole Health Dictionary

See tiabendazole.... thiabendazole

A tropical disease caused by a female parasitic worm more than 1 m long. Infection is the result of drinking water containing the water flea cyclops, which harbours larvae of the worm. The larvae pass through the intestine and mature in body tissues. After about a year, the adult female worm, now pregnant, approaches the skin surface and creates an inflamed blister that bursts, exposing the end of the worm. Urticaria, nausea, and diarrhoea often develop while the blister is forming. The disease occurs in Africa, South America, the Caribbean, Middle East, and India.

The traditional remedy is to wind the worm from the skin on to a small stick. Once the worm is out, the condition usually clears up. The drugs tiabendazole and niridazole are given to reduce inflammation, antibiotics are given to control secondary infection, and the patient is immunized against tetanus.... guinea worm disease

An infestation of the intestines by the parasitic worm STRONGYLOIDES STERCORALIS. It is widespread in the tropics. Strongyloidiasis is contracted in affected areas by walking barefoot on soil contaminated with faeces. Larvae penetrate the soles, migrating via the lungs and throat to the intestine. Here they develop into adults and produce larvae. Most larvae are passed in the faeces, but some enter the skin around the anus to begin a new cycle. A person may be infested for more than 40 years.

The larvae cause itching and red weals where they enter the skin. In the lungs they may cause asthma or pneumonia. Heavy intestinal infestation may cause swelling of the abdomen and diarrhoea. Occasionally, an infected person with reduced immunity dies of complications, such as septicaemia or meningitis.

Treatment with an anthelmintic drug, usually tiabendazole, kills the worms.... strongyloidiasis

An infestation of humans, usually children, with the larvae of TOXOCARA CANIS: a small, threadlike worm that lives in the intestines of dogs. Children who play with an infested dog or soil contaminated with dog faeces, and who then put their fingers in their mouths, may swallow some of the worm eggs. The eggs hatch in the intestines, and the released larvae migrate to organs such as the liver, lungs, brain, and eyes. Usually, infestation causes mild fever and malaise, which soon clears up; but heavy infestation may lead to pneumonia and seizures. Loss of vision may occur if larvae enter the eye and die there.

A diagnosis is made from sputum analysis, and by a liver biopsy. Severe cases require treatment in hospital with tiabendazole and an anticonvulsant drug.... toxocariasis

(larva migrans) a skin disease caused either by larvae of certain nematode worms (e.g. Ancylostoma braziliense) normally parasitic in dogs and cats or by the maggots of certain flies (see Hypoderma; Gasterophilus). The larvae burrow within the skin tissues, their movements marked by long thin red lines that cause the patient intense irritation. The nematode infections are treated with albendazole, ivermectin, or tiabendazole; maggots can be surgically removed.... creeping eruption

n. one of a group of chemically related antifungal drugs that are also effective against a wide range of bacteria; some (e.g. *tiabendazole and *mebendazole) are also used as anthelmintics. The group includes *econazole, *clotrimazole, *ketoconazole, and *miconazole.... imidazole