n. a tiny fibre occurring in bundles in the cytoplasm of cells that lie in contact, as in epithelial tissue. Tonofibrils are concerned with maintaining contact between adjacent cells. See desmosome.
n. an area of contact between two adjacent cells, occurring particularly in epithelia. The cell membranes at a desmosome are thickened and fine fibres (tonofibrils) extend from the desmosome into the cytoplasm.... desmosome