(videokeratography) an imaging technique used to study the shape and refractive power of the cornea in detail. An image projected onto the cornea is analysed by a computer to produce a representation of the shape and refractive power of the corneal surface. Corneal topography has an important role in the management of corneal disease and refractive surgery.... corneal topography
n. the study of the different regions of the body, including the description of its parts in relation to the surrounding structures. —topographical adj.... topography
any one of a class of *cytotoxic drugs that work by blocking the action of topoisomerase enzymes, which promote the uncoiling of the DNA double helix, a necessary preliminary to replication. Topoisomerase I inhibitors include irinotecan, used for treating advanced colorectal cancer (especially in combination with *fluorouracil); and topotecan, given for treating advanced ovarian cancer, relapsed small-cell lung cancer, and recurrent cervical cancer. Side-effects include delayed but severe diarrhoea and reduction in blood-cell production by the bone marrow. Topoisomerase II inhibitors include *etoposide and *doxorubicin.... topoisomerase inhibitor
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