Grapefruit (Citrus • paradisi).Plant Part Used: Fruit.Dominican Medicinal Uses: Fruit: juice, orally, for diabetes, constipation, indigestion and intestinal obstruction.Safety: Fruit and juice are widely consumed and generally considered safe.Drug Interactions: Cytochrome P450-metabolized drugs (may inhibit potency or potentiate activity).Laboratory & Preclinical Data: In vivo: anticancer, chemopreventive (essential oil); anti-ulcer, gatroprotective (seed extract).In vitro: inhibition of acetylcholinesterase activity (essential oil), inhibition of cytochrome P450 enzymes (fruit juice).* See entry for Toronja in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.
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