a gene that is expressed (i.e. manifests its effects) 60–100 times more in cancerous prostate tissue than in benign prostate tissue. A test for PCA3 can be performed on urine passed just after a digital rectal examination of the prostate; uPM3 – the first such test to be developed – is a far more specific indicator of the presence of prostate cancer than tests for *prostate specific antigen (PSA), increased amounts of which are produced in both malignant and nonmalignant prostate tissue. However, the test is not as sensitive as PSA in detecting the presence of prostate cancer.... pca3
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