Valeriana dubia Health Dictionary

Valeriana Dubia: From 1 Different Sources


Bunge.

Synonym: V. officinalis auct. non Linn.

Family: Valerianacea.

Habitat: Western Himalayas, Kashmir at Sonamarg at 2,4002,700 m.

English: Common Valerian.

Action: Rhizome and roots— sedative, hypotensive, cardiotonic; depressant on CNS, antispasmodic; used for hysteria, neurosis, nervousness, hypochondriasis.

The roots and rhizomes yielded alkaloids—dipyridylmethylketone, ac- tinidine, iso-valeramide and valerian- ine; sesquiterpene ketone-valeranone. Bornyl acetate is the major constituent of the root oil, 31.5%, whereas it is only 6.6% in leaf oil. Bornyl isovalerate is reported from the root oil.

Baalaka is a confusing synonym of Tagara. It should be equated with Pavo- nia odorata Willd. (Malvaceae).

Baalaka (syns: Ambu, Baala, Barhi- shtha, Hrivera, Jala, Kacha, Muurd- haja, Udichi, Udichya) is known as Sugandhabaalaa in Northern markets. In South India Coleus vettiveroides K. C. Jacob (Labiateae) is preferred as Baalaka. Delphinium brunonianum Royle (Ranunculaceae), with synonyms Kutila, Nata, Vakra, is also used as Tagara.

Valeriana leschenaultii DC. var. brunoniana C. B. Clarke.

Family: Valerianaceae.

Habitat: The temperate Himalayas from Kashmir to Bhutan at altitudes of 1,200-3,60 m and in the Khasi and Jaintia hills between 1,500 and 1,800 m.

Folk: Sugandhabaalaa, Tagger, Taggar-ganthodaa. Asaarun (Ku- maon).

Action: Used as V. jatamansi and V officinalis.

Valeriana hardwickii is known as Taggar-ganthodaa in Mumbai and Asaarun in Kumaon. In Unani medicine, Asaarun is equated with Asarum europaeum Linn. (Aristolochiaceae). It is known as Subul-e-barri, Naardin- barri and Persian Tagar; Wild Nard, Hazel Wort and Asarabacca in English. Though sedative and brain tonic, Asaarun should not be equated with Tagara.

Family: Valerianaceae.

Habitat: Karnakata and the Nilgiris.

Ayurvedic: Tagara (related species).

Folk: Sugandhabaalaa, Taggar, Baalaka.

Action: Used as a substitute for valerian.

Health Source: Indian Medicinal Plants
Author: Health Dictionary

Valeriana Officinalis

Linn.

Family: Valerianaceae.

Habitat: Native to Eurasia. (V officinalis auct. non Linn. is found in Kashmir at Sonamarg at 2,4002,700 m)

English: Valerian, Garden Heliotrope, Common Valerian.

Ayurvedic: Tagara, Nata. Baalaka (syn. Udichya, Jala, Barhishtha) is also equated with Valeriana sp.

Folk: Sugandhabaalaa, taggar.

Action: Tranquillizer, hypnotic, a natural relaxant to higher nerve centres. Used for nervous tension, sleeplessness, restlessness, palpitation, tension, headache, migraine, menstrual pain, intestinal cramps, bronchial spasm.

Key application: Internally for restlessness and sleeping disorders based on nervous conditions (German Commission E). (See Expanded Commission E, ESCOP and WHO monographs.)

Constituents of the root include val- trates, didrovaltrates and isovalerates. Other constituents include 0.4-1.4% monoterpenes and sesquiterpenes, caf- feic, gamma-aminobutyric (GABA) and chlorogenic acids, beta-sitosterol, methyl, 2-pyrrolketone, choline, tannins, gums alkaloids and resin. (Expanded Commission E Monographs.)

The volatile oil (0.5-2%) contains bornyl acetate and bornyl isovalerate as the principal components. Other constituents include beta-caryophyllene, valeranone, valerenal, valerenic acid and other sesquiterpenoids and mono- terpenes.

The co-occurrence of three cyclo- pentane-sesquiterpenoids (valerenic acid, acetoxyvalerenic acid and valere- nal) is confined to Valeriana officinalis L. and permits its distinction from V edulis and V. Wallichii. (WHO.)

The important active compounds of valerian are the valepotriates (iridoid molecules) and valeric acid. Originally it was thought that valepotriates were responsible for the herbs sedative effect, but, later on, an aqueous extract of the root has also been shown to have a sedative effect. Since valepotriates are not soluble in water, it was concluded that valerenic acid is also the chemical factor responsible for the sedative effect of the herb. Most commercial extracts in Western herbal are water-soluble extracts standardized for valerenic acids.

Large doses ofvalepotriates from the herb decreased benzodiazepines and diazepam withdrawl symptoms in rats. At low doses valerian enhances binding of flunitrazepam, but at high doses it inhibits binding of the drug. Valerenic acid inhibits breakdown of GABA, and hydroxypinoresinol binds to benzodi- azepine receptor. (Sharon M. Herr.)

The safety of valepotriates has been questioned.

Currently valerian is an approved over-the-counter medicine in Germany, Belgium, France, Switzerland and Italy. (The British Herbal Compendium.)

See Valeriana dubia Bunge, syn. V. officinalis auct. non Linn., known as Common Valerian.... valeriana officinalis

Valeriana Pyrolaefolia

Decne.

Family: Valerianaceae.

Habitat: The temperate Himalayas from Kashmir to Bhutan.

Ayurvedic: Dhyaamaka (including among aromatic drugs of Jatamansi group.)

Folk: Sugandhabaalaa.

Action: Used as V. jatamansi.... valeriana pyrolaefolia

Valeriana Wallichii

DC.

Synonym: V. jatamansi Jones. Nardostachys jatamansi (Jones) DC.

Family: Valerianaceae.

Habitat: Temperate Himalayas from Kashmir to Bhutan, above 3,000 m, and Khasia Hills.

English: Indian Valerian.

Ayurvedic: Tagara, Sugandhabaalaa, Kaalaanusaari, Kaalaanusaarikaa, Nata. (Delphinum brunonianum Royle, Ranunculaceae, syn. Kutila, Nata, Vakra, is also used as Tagara.)

Unani: Asaarun, Tagar Reshewaalaa.

Siddha: Tagarai.

Folk: Taggar, Baalaka, Mushkbaalaa, Asaarun, Tagar-ganthodaa.

Action: Rhizomes and roots— used as a substitute for Valeriana officinalis; prescribed as a remedy for hysteria, nervous unrest and emotional troubles, and as a sedative.

Rhizomes and roots contain cyclop entapyrans, acacetin-7-O-rutino- sides, valtrate, didrovaltrate, linarin iso-valerinate, valepotriates and an iri- doid ester glycoside, valerosidatum. Cyclopentapyrans exhibit sedative, tranquilizing and bacteriocidal properties.

Valtrate and didrovaltrate were cy- totoxic to hepatoma cells in culture and inhibited synthesis of DNA and protein in tumor cells.

Root—spasmolytic. Essential oil— antibacterial. (Indian Valerian oils are considered poor as compared to those of V. officinalis oils.) The essential oil from roots contains calarene, beta- bargamotene, valeranone, ar-curcu- mene, maalioxide and maalitol. Main acids present are isovaleric acid and (+)-beta-methyl valeric acid.

Valeriana jatamansi auct. non Jones, synonyms Nardostachys grandiflora DC. and N. jatamansi DC. is equated with Indian Spikenard, Musk-Root and Jataamaansi.

Dosage: Rhizome—1-3 g powder. (API, Vol. I.)... valeriana wallichii



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