Vallaris solanacea Health Dictionary

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Vallaris Solanacea: From 1 Different Sources

Kuntze

Synonym: V. heynei Spreng. V. dichotoma (Roxb.) Wall. ex G. Don.

Family: Apocynaceae.

Habitat: Throughout India; cultivated in gardens.

Ayurvedic: Aasphotaa, Asphuka, Bhadravalli, Saarivaa-utpala (white var.).

Folk: Haapharamaali var. Dudhi-bel (Garhwal).

Action: Latex—applied to old wounds and sores (mildly irritant). Bark—astringent. Seeds—cardiac tonic.

Seeds are rich in cardiac glyco- sides; contain acoschimperoside P, mono-O-acetylvallaroside, mono-O- acetylsolanoside, mono-O-acetylaco- schimperoside P, vallaroside, valla- rosolanoside, solanoside and 16-deace- tyl-16-anhydroacoschimperoside P. O- acetylsolanoside is a potent cardioton- ic.

The seed oil contains palmitic, oleic and linoleic acids. The leaves gave beta-sitosterol, beta-amyrin and urso- lic acid.

Vallaris glabra Kuntze (West Bengal) is also equated with Aasphotaa.

Health Source: Indian Medicinal Plants
Author: Health Dictionary

Atropa Acuminata Royle Ex

Lindl.

Synonym: A. belladonna auct. non L.

Family: Solanaceae.

Habitat: Kashmir and Himachal Pradesh up to 2,500 m.

English: Indian Belladonna, Indian Atropa.

Ayurvedic: Suuchi.

Unani: Luffaah, Luffaah-Barri, Yabaruj, Shaabiraj.

Action: Highly poisonous; sedative, narcotic, anodyne, nervine, antispasmodic (used in paralysis); parkinsonism; encephalitis; carcinoma; spastic dysmenorrhoea; whooping cough, spasmodic asthma; colic of intestines, gall bladder or kidney, spasm of bladder and ureters; contraindicated in enlarged prostate.

Key application: In spasm and colic-like pain in the areas of the gastrointestinal tract and bile ducts. (German Commission E, The British Herbal Pharmacopoeia.) It is contraindicated in tachycardiac arrhythmias, prostate adenoma, glaucoma, acute oedema of lungs.

A. belladonna L. (European sp. Belladonna, Deadly Nightshade) is cultivated in Kashmir and Himachal Pradesh.

The herb contains tropane (tropine) or solanaceous alkaloids (up to 0.6%), including hyoscamine and atropine; flavonoids; coumarins; volatile bases (nicotine).

Tropane alkaloids inhibit the para- sympathetic nervous system, which controls involuntary bodily activities; reduces saliva, gastric, intestinal and bronchial secretions, and also the activity of urinary tubules. Tropane alkaloids also increase the heart rate and dilate the pupils. These alkaloids are used as an additive to compound formulations for bronchitis, asthma, whooping cough, gastrointestinal hy- permotility, dysmenorrhoea, nocturnal enuresis and fatigue syndrome.

Atropine provides relief in parkin- sonism and neurovegetative dystonia.

The root is the most poisonous, the leaves and flowers less, and the berries the least. (Francis Brinker.)

Dosage: Leaf, root—30-60 mg powder. (CCRAS.)... atropa acuminata royle ex

Capsicum Annuum

Linn.

Family: Solanaceae.

Habitat: Native to the West Indies and tropical America; now cultivated throughout tropical regions of India.

English: Chilli, Red Pepper.

Ayurvedic: Raktamaricha, Lankaa, Katuviraa.

Unani: Mirch, Filfil-e-Ahmar, Filfl-e-Surkh, Surkh Mirch.

Siddha/Tamil: Milagay.

Action: Stimulant, accelerates oxygenation of cells, encourages adrenal glands to produce corticos- teroids, increases gastrointestinal secretion. Carminative, antispas- modic, antiseptic. Used externally for rheumatism, backache, lumbago, neuralgia, painful muscle spasm.

Red chilli contains capsaicin (0.11.5%), carotenoids, flavonoids, volatile oil; steroidal saponins (capsicidins, only in seeds).

Capsaicin stimulates the circulation and alters temperature regulation; topically desensitizes nerve endings and acts as a local analgesic.

Capsaicin produces a protective effect in rat lung and liver by strengthening the pulmonary antioxidant enzyme defence system. Acute capsaicin treatment causes release of substance desensitization of the respiratory tract mucosa to a variety of lung irritants.

Red pepper or an equivalent amount of capsaicin, when fed along with cholesterol-containing diets to female albino rats, prevented significantly the rise of liver cholesterol levels.

Vitamin P has been isolated from the chillies. Vitamin C gradually increases during maturation and reaches maximum at the semi-ripe or pink coloured stage and decreases thereafter.

Capsaicin exhibited a hypoglycae- mic effect in dogs; insulin release was increased. (Phytother Res, 2001, Aug 15(5), 391-4.)

Dosage: Fruit—30-60 mg powder. (CCRAS.)... capsicum annuum

Capsicum Frutescens

Linn.

Family: Solanaceae.

Habitat: Cultivated as a condiment crop.

English: Bird Chilli.

Ayurvedic: Katuviraa.

Unani: Surkh Mirch.

Siddha/Tamil: Musi Milagay.

Action: See Capsicum annuum.

Key application: Externally, in painful muscle spasms in areas of shoulder, arm and spine; for treating arthritis, rheumatism, neuralgia, lumbago and chilbains. (German Commission E.) The British Pharmacopoeia reported rubefacient and vasostimulant action.

The plant contains hydroxybenzoic acid, hydroxycinnamic acid and ascorbic acid. Fruits contain up to 1% of capsaicin.... capsicum frutescens

Datura

Datura metel

Solanaceae

San: Dhustura Hin.: Kaladhatura

Ben: Dhatura Mal: Ummam Kan; Dattura

Tam: Vellummattai

Tel: Tellavummetta

Importance: Downy datura or thorn apple is an erect branched under shrub whose intoxicating and narcotic properties have been made use of by man from ancient time. The plant and fruit are spasmolytic, anticancerous and anthelmintic. Leaves and seeds are inhaled in whooping cough, asthma and other respiratory diseases. Root, leaf and seed are febrifuge, antidiarrhoeal, anticatarrhal and are used in insanity, cerebral complications and skin diseases. Leaf is antitumour, antirheumatic and vermicide. Flower is antiasthamatic, anaesthetic and is employed in swellings and eruptions on face. Fruit juice is used in earache and seed decoction in ophthalmia. For the rheumatic swellings of joints, lumbago, sciatica and neuralgia, warm leaf smeared with an oil is used as a bandage or sometimes the leaf is made into a poultice and applied. The root boiled with milk is used in insanity. It is also an ingredient in the ayurvedic preparation Kanakasva used in bronchial troubles, and the Unani formulations “Roghan dhatura” used as a massage oil for the paralysed part. The alkaloids of pharmaceutical interest present in the plant are hyoscyamine, hyoscine and meteloidine. Datura is the chief commercial source of hyoscine available from natural source. Hyoscine, in the form of hyoscine hydrobromide, is used as a pre-anaesthetic in surgery, child birth, ophthalmology and prevention of motion sickness. It is also employed in the relief of withdrawal symptoms in morphine and alcoholic addiction, paralysis agitans, post- encephaletic parkinsonianism and to allay sexual excitement. Hyoscyamine and its salt hyoscyamine sulphate and hyoscyamine hydrobromide are used in delerium, tremour, menia and parkinsonianism (Kaul and Singh, (1995).

Distribution: Datura is distributed throughout the world, particularly the warmer regions. Datura stramonium is indigenous to India. Out of 15 species reported from different parts of the world, only 10 are known to occur in India. They are found commonly in wastelands, gardens and roadsides. They are distributed in rich localities under semi -arid and arid regions of Punjab, Haryana, Rajastan, and Gujarat; the Central Plateau of Andhra Pradesh and Maharastra and the southern peninsular region of Tamil Nadu. Datura innoxia is indigenous to Mexico and is distributed in Latin American countries. A wealth of genetic stock on genotypes and varieties are maintained in several research institutes in Germany, Bulgaria, USSR and Poland.

Botany: The genus Datura, belonging to the family solanaceae, consists of annual and perennial herbs, shrubs and trees. Three species,viz, Datura metel Linn., D. stramonium Linn. and D. innoxia Mill. are medicinally important. D. innoxia mill. and D. metel Linn. (var. alba, and var, fastuosa) are the choice drug plants, rich in hyoscine. D. metel Linn. is the most common in India. The names, D. metel Linn., D. fastuosa Linn., D. alba Nees., D. fastuosa Linn. var. alba (Nees) C.B. Clarke and D. metel Linn. var. fastuosa (Linn.) Safford are synonymously used by many workers. Two varieties are often noted in D. metel Linn., namely the white flowered var. alba and purple flowered var. fastuosa. D. metel Linn. is an erect succulent branched undershrub divaricate often purplish branches and ovate pubescent leaves which are oblique at the base of lamina. Flowers are large, solitary, short pedicelled, purplish outside and white inside. Fruits are sub-globose capsules covered all over with numerous, fleshy prickles, irregularly breaking when mature. Seeds are numerous, smooth, yellowish brown. (warrier et al, 1994).

Agrotechnology: Datura grows well in a wide range of climate from tropical to temperate conditions.

The plant thrives best in areas of low rainfall where winter and monsoon rains are followed by long dry periods. Areas with annual rainfall below 1000mm with mean temperature of 10-15oC in winter and 27 - 28oC in May-June are ideal. The crop cannot stand frost, high rainfall or high temperature in the plains in May-June. It grows on majority of soils, however, alkaline or neutral clay loam soil or those tending to saline-alkaline reaction rich in organic matter are ideal for vigorous growth. The clayey, acidic, water-logged or moisture deficient soils do not suit this crop.

The plant is propagated by seeds but it is characterised by poor and often erratic seed germination which can be improved either by leaching out the inhibitor from the seeds or by alternate freezing and thawing of seeds. The optimum season for raising the crop is Rabi in tropical and subtropical areas while Kharif in temperate areas. The seeds can be broadcast - sown or seedlings can be raised in nursery and then transplanted. Seed rate is 7-8 kg/ha for broadcasting and 2-3 kg/ha. for transplanting. The field is ploughed and disced adequately to produce fine seed bed. In the case of direct seeding, seeds are drilled in rows taken 45-60 cm apart. The plants are thinned to keep a spacing of 30-45 cm at the time of first weeding. In the case of transplanting 4-6 weeks old seedlings are planted at 45-60 x 30-45 cm spacing. The field should be irrigated immediately after sowing or planting if soil moisture is inadequate. Thereafter 3-4 irrigations may be given if sufficient rainfall is not received. Application of organic manure at 10-15 t/ha and fertilisers at 60:40:40 kg N, P2O5 and K2O/ha is recommended for the crop for better growth and yield N may be applied in 3-4 equal split doses at planting and after each weeding which is required 2-3 times during the growing season. Application of micronutrients is reported to improve the alkaloid contents. No major insect pest is known to attack this crop. However, leaf spot, wilt and mosaic diseases cause damage to this crop. Leaf spot is caused by Alternaria tennuissima (Nees) Wiltshire and characterised by brown round to oval spots, becoming necrotic at later stage which leads to withering and dropping of leaves. Wilt is caused by Sclerotium rolfsii Sace; it starts with dropping of leaves and finally wilting of the entire plant. Root and foot wilt, caused by Corticium solani, appears as damping off of seedlings and mature plants. Datura distortion mosaic is characterised by yellowing of the veins followed by inward rolling and distortion of leaves with a reduction in plant size. For reducing the impact of these diseases, field sanitation, use of resistant varieties, crop rotation for 3-4 years and fungicide application should be resorted to. For the purpose of leaf and top, harvesting is done as soon as flowering starts. Entire top containing leaves and twigs is cut, dried in shade and stored in gunny bags. For seed and fruit, fully grown fruits, still green are picked 2-3 times before final harvest when the entire plant is cut from the base and dried in the open. The dried fruits are then thrashed with a stick to separate the seeds. The seed yield is 1-1.5 t/ha. (Husain, 1993; Kaul and Singh, 1995)

Properties and activity: The alkaloids hyoscyamine and hyoscine (scopolamine) and meteloidine are found in all parts of the plant. The total alkaloid content is 0.26 - 0.42 % Fruits contain daturaolone and daturadiol while roots contain additionally ditigloyloxy tropane derivatives, tigloidine, apohyoscine, norhyoscine, norhyocyamine, cusiohygrine and tropine. Other alkaloids isolated from the plant are apohyoscyamine, DL-scopolamine, normeteloidine, tigloylputrescine, scopine, nortigloidine, tropine, psuedo valeroidine, fastudine, fastunine, fastusinine, 7-hydroxy-3, 6-ditigloyloxytropane (2) datura nolone and fastusic acid. The physiological effects of hyoscyamine are qualitatively the same as those of its recemic derivative atropine. This is relatively more active in its paralysing affect on nerve endings and less active in its stimulant action on the central nervous system. The sedative and hypnotic action of hyoscyamine is weaker than that of hyoscine. Atropine has a stimulant action on the central nervous system and depresses the nerve endings to the secretary glands and plain muscles. The plant or the different alkaloids have narcotic, anthelmintic, spasmolytic anaesthetic, sedative, ophthalmic, anticancerous, antitumour, antirheumatic, antiasthmatic, antidiarrhoeal and anticatarrhal activities. (Thakur et al, 1989).... datura

Datura Alba

Nees.

Family: Solanaceae.

Habitat: Throughout India in plains; wastelands, roadsides and gardens.

Ayurvedic: Dhattuura (white var.). (Dhattura consists of dried seeds of Datura sp.)

Unani: Dhaturaa.

Action: See D. Metel Linn.... datura alba

Physochlaina Praealta

Miers.

Family: Solanaceae.

Habitat: Lahul valley (Punjab), Ladakh, North Kashmir. Western Tibbet at altitudes of3,300-4,600 m.

Folk: Daturaa (Ladakh), Laangtaan; Sholar, Bajarbang (Punjab).

Action: Leaves—poisonous and narcotic.

The roots of the plant contain 0.64% alkaloids (calculated as hyoscyamine). The plant constitutes an excellent source of atropine.... physochlaina praealta

Cayenne

Capsicum minimum. N.O. Solanaceae.

Synonym: African Pepper, Bird Pepper, Guinea Pepper and Chillies.

Habitat: There are many varieties of the shrub, which is indigenous to India, Africa and South America.

Features ? The oblong-conical shaped pods are fiery to the taste, and the numerous seeds contain a large amount of oil, which has a similar effect on the palate. The fruit itself, however, differs widely in size, colour and strength. The yellowish-red product of Sierra Leone is the most pungent, the long, bright red type from Japan being much milder.

(Capsicum annum is cultivated in Hungary, and fed to canaries in order to improve the appearance of the plumage. Known as "tasteless Cayenne," this is quite free from pungency.)

Part used ? Dried, ripe fruit. Used for medicinal and culinary purposes.

Action: Cayenne is acknowledged as the finest stimulant in the herbal materia medica, and is, in addition, carminative, tonic, diaphoretic and rubifacient.

As a pure stimulant, the administration of Cayenne produces a natural warmth and uniform circulation, and in dyspepsia and flatulence the carminative effect is especially noticeable. As a diaphoretic it may be used whenever it is desired to open the pores and bring about increased perspiration.

Capsicum is a constituent of many of the herbal compounds, including the well-known composition powders, Thomson's formula for which will be found in the appropriate section of this book. The dose of the powdered fruit is 5-20 grains.

Coffin is a champion of the virtues of Capsicum, one of his reasons being that, unlike most of the stimulants of allopathy, it is not a narcotic.... cayenne

Datura Innoxia

Mill.

Synonym: D. metel auct. non Linn.

Family: Solanaceae.

Habitat: Western Himalayas and hilly regions of the western parts of Peninsular India, abundantly in Maharashtra.

English: Thornapple.

Ayurvedic: Dhattuura.

Unani: Dhaturaa, Joz Maasil.

Action: The plant is the source of alkaloid scopolamine which is used as a pre-anaesthetic in surgery and childbirth, in ophthalmology and for the prevention of motion sickness.

Hyoscyamine and hyoscine and me- teloidine were found in the leaves, flowers, pericarp and seeds of the plant. The root gave tropane, tropine and pseu- dotropine.... datura innoxia

Datura Metel

Linn.

Synonym: D. fastuosa Linn.

Family: Solanaceae.

Habitat: Throughout India, particularly in waste place.

English: Thornapple, Downy Datura.

Ayurvedic: Dhattuura, Dhuurta, Dhastura, Unmatta, Shivapriya, Harapriya, Hema, Haatta, Dhustuu- ra, Dhustuuraka, Kanaka, Maatula. Also equated with Raaj-dhatuura. (white var.)

Unani: Dhaturaa.

Siddha/Tamil: Oomatthai, Karu- voomatthai.

Action: Various plant parts are used in headache, hemiplegia, epilepsy, delirium, convulsions, cramps, rigid thigh muscles, rheumatism. Leaf— antitumour, antirheumatic. Leaf and corolla—anti-inflammatory. Flower—antiasthmatic. Seed, leaf and root—anticatarrhal, febrifuge, antidiarrhoeal, antidermatosis; also used in cerebral complications. Seeds—used in asthma. Limited use in kinetosis (excessive salivation, nausea and vomiting).

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia ofIndia indicated the use of the whole plant in dysuria and alopecia.

The plant accumulates more hyos- cine than hyoscyamine. Hyoscine content of dried leaves and flowering tops—between 0.02-0.55%. Alkaloid content of leaves—0.55%; stem—0.4%; seeds—0.19%; pericarps—0.8%; root at flowering of the plant—0.77%.

Hyoscine in large doses causes delirium and coma.

Dosage: Seed—30-60 mg. (API Vol. III.)... datura metel

Solanum Aculeatissimum

Jacq.

Family: Solanaceae.

Habitat: Assam and Kerala, in damp and waste places.

Ayurvedic: Brihati (related species, used in Kerala). Brihati and Kantakaari have been used in Indian medicine as synonyms.

Action: Both fruit and leaves contain glycoalkaloid solanine; immature fruits contain more of it than the ripe ones. Air-dried leaves and fruits contain 0.26 and 0.14% of alkaloids, respectively. See S. indicum Linn.... solanum aculeatissimum

Solanum Dubium

Fresen.

Family: Solanaceae.

Habitat: Sandy coast of Saurashtra (Gujarat).

Ayurvedic: Kantakaari (related species).

Action: Seeds are soaked and eaten in Africa for the treatment of venereal diseases. See S. xanthocarpum.... solanum dubium

Solanum Spirale

Roxb.

Family: Solanaceae.

Habitat: Assam, Khasi Hills. Banga (Bengal); Titakuchi (Assam); Soh- jhari (Khasi); Mungas-kajur (root, Bihar).

Action: Root—diuretic, narcotic. Unripe berries—poisonous.

The leaves contain 1.29% alkaloids. Partial synthesis of etiolin has been reported.... solanum spirale

Solanums

Solanum spp.

Solanaceae

Solanums comprise a very important group of medicinal plants having multifarious uses.

These plants belong to the family Solanaceae and genus Solanum. A number of species are reported to be medicinal which are briefly described below.

1. S. anguivi Lam. syn. S. indicum auct. non Linn.

Eng: Poison berry; San: Brhati, Simhi;

Hin: Barhauta, Birhatta;

Mal: Puthirichunda, Cheruchunda;

Tam: Karimulli, Puthirichundai;

Kan: Ramagulla;

Tel: Cittimulaga, Tellamulaka It is found throughout the tropics, in plains and at low elevations. It is much branched, very prickly undershrub, 0.3-1.5m in height. Leaves are simple, large, ovate, subentire, sinuate or lobed. Flowers are blue in extra-axillary cymes having stellately hairy and prickly peduncles. Fruits are globose berries, reddish or dark yellow with smooth or minutely pitted seeds. Its roots are useful in vitiated conditions of vata and kapha, odontalgia, dyspepsia, flatulence, colic, verminosis, diarrhoea, pruritus, leprosy, skin diseases, strangury, cough, asthma, bronchitis, amenorrhoea, dysmenorrhoea, fever, cardiac disorders and vomiting. Roots bitter, acrid, astringent, thermogenic, anodyne, digestive, carminative, anthelmintic, stomachic, constipating, resolvent, demulcent, depurative, diuretic, expectorant, aphrodisiac, emmenagogue, febrifuge and cardiotonic.

2. S. dulcamara Linn.

Eng: Bittersweet, Bitter night shade; San: Kakmachi; Pun: Rubabarik It is found in tropical situations in India and Sikkim. The plant is rich in alkaloidal glycosides like solamarine, tomatidenol, solasodine and soladulcine. The berry and twig are alterative, antisyphilitic, diaphoretic, resolvent, narcotic, diuretic, antirheumatic and used in liver disorders and psoriasis.

3. S. erianthum D. Don, syn. S. verbascifolium auct. non Linn.

San: Vidari;

Hin: Asheta;

Mal: Malachunda;

Tam: Malaichundai, Anaisundaikkai

Pun: Kalamena;

Tel: Rasagadi

The plant is distributed over the tropical and subtropical zones of India. The plant contains alkaloids and steroidal sapogenins. Leaves and fruits contain solasodine, solasodiene, solafloridine, diosgenin, vespertilin and pregnenolone. The plant is CNS depressant, antiinflammatory and useful in burns.

4. S. melongena Linn.

Eng: Brinjal, Egg plant; San: Varttaki;

Hin: Bengan, Badanjan;

Mal: Vazhuthina

Tam: Kattirikkai;

Kan: Badanekaya, Doddabadane;

Tel: Vankaya, Niruvanga

It is mainly cultivated as a vegetable throughout the tropics and subtropics. It is an erect or suffrutescent, herbaceous, armed or unarmed perennial shrub. Leaves are simple, large, entire and lobed. Flowers are blue, in clusters of 2-5. Fruits are large, white, yellow or dark purple berries of different shapes capped with thick persistent calyx. Seeds are many, yellow or cream and discoid. The roots, leaves and unripe fruits are useful in cholera, bronchitis, asthma, odontalgia and fever. The roots are laxative, analgesic and cardiotonic. Leaves are sialagogue, narcotic and antiherpetic. The unripe fruits are bitter, acrid, sweet, aphrodisiac, cardiotonic and haematinic.

5. S. melongena var. incanum (Linn.) Prain syn. S. incanum Linn., S. coagulens Forsk.

San: Brihati;

Hin: Baigan;

Mal: Cheruvazhuthina

It is a herbaceous prickly plant found in warm humid tropics. It is grown almost throughout the year in the plains and during summer on the hills. It grows 0.6-2m in height. Leaves are simple, alternate lobed. Flowers are blue or white, 5 lobed, calyx with spines. Fruits are ellipsoid berries. The plant is a constituent of the dasamoola which helps to overcome vitiated tridoshas and cures dyspepsia, fever, respiratory and cardiac disorders, skin ailments, vomiting, ulcers and poisonous affections. In Ayurveda the formulations like Brihatyadi Kashaya, dashamoolarishta, Indukantaghritam, Dasamoolaharithaki, etc are the important preparations with the roots. It is also used in the treatment of toothache and sore throat. The fruit is reported to stimulate the intrahepatic metabolism of cholesterol. Roots are antiasthmatic and stimulant. Leaves are used in cholera, bronchitis and asthma. Fruits are useful in liver complaints.

6. S. nigrum Linn. syn. S. rubrum Mill.

Eng: Black night shade; San: Kakamachi;

Hin: Makoy, Gurkkamai;

Mal: Karimthakkali;

Tam: Manathakkali, Milagutakkali;

Kan: Kakarndi;

Tel: Kamachi, Kachi

It is seen wild throughout India. It is an erect, divaricately branched, unarmed, suffrutescent annual herb. Leaves are ovate or oblong, sinuate-toothed or lobed and glabrous. Flowers are 3-8 in extra-axillary drooping subumbellate cymes. Fruits are purplish black or reddish berries. Seeds are many, discoid, yellow, minutely pitted. The whole plant is useful in vitiated conditions of tridosha, rheumatalgia, swellings, cough, asthma, bronchitis, wounds, ulcers, flatulence, dyspepsia, strangury, hepatomegaly, otalgia, hiccough, opthalmopathy, vomiting, cardiopathy, leprosy, skin diseases, fever, splenomegaly, haemarrhoids, nephropathy, dropsy and general debility. The plant is bitter, acrid, emollient, antiseptic, antiinflammatory, expectorant, anodyne, vulnerary, digestive, laxative, diuretic, cardiotonic, depurative, diaphoretic, febrifuge, rejuvenating, sedative, alterant and tonic.

7. S. spirale Roxb.

Hin: Munguskajur

It is seen wild in Assam and Khasi hills in India. Its root is diuretic and narcotic.

8. S. stramoniifolium Jacq., syn. S. ferox auct. non Linn.

San: Garbhada;

Hin: Rambaigan;

Mal: Anachunda;

Tam: Anaichundai;

Tel: Mulaka

It is observed in India in the states of Assam, Maharashtra, Karnataka and Tamil Nadu. Its berries contain glycoalkaloids such as solasonine and solasodine. Its roots and berries are bechic, antiasthmatic, antirheumatic, antiviral, anticancerous and spermicidal.

9. S. surattense Burm. F. syn. S. xanthocarpum schrad. & Wendl., S. jacquinii Willd.

Eng: Yellow-berried nightshade; San: Kantakari, Nidigdhika;

Hin: Remgani,Kateli;

Mal: Kantakarichunda;

Tam: Kantankattiri;

Kan: Nelagulli;

Tel: Callamulaga

It is found throughout India and Pakistan in dry situations as weed on roadsides and wastelands. It is prickly, diffuse, bright green, suffrutescent, perennial undershrub, with zigzag branches. Leaves are ovate-oblong, hairy on both sides and armed on the midrib and the nerves. Flowers are bluish purple, in extra-axillary cymes. Fruits are glabrous, globular drooping berry, yellow or white with green veins, surrounded by the calyx. Seeds are many, small, reniform, smooth and yellowish brown.

The whole plant is useful in vitiated conditions of vata and kapha, helminthiasis, dental caries, inflammations, flatulence, constipation, dyspepsia, anorexia, leprosy, skin diseases, hypertension, fever, cough, asthma, bronchitis, hiccough, lumbago, haemorrhoids and epilepsy. The plant is bitter, acrid, thermogenic, anthelmintic, antiinflammatory, anodyne, digestive, carminative, appetiser, stomachic, depurative, sudorific, febrifuge, expectorant, laxative, stimulant, diuretic, rejuvenating, emmenagogue and aphrodisac. Fruits contain solasonine, solamargine and solasodine.

10. S. torvum Sw.

Eng: West Indian Turkey Berry;

Hin,

Ben: Titbaigan;

Mal: Kattuchunda;

Kan: Kadu Sunde;

Tam: Sundaikai, Amarakai;

Tel: Kundavustic, Kotuvestu; Ass: Hathibhekuri

It is seen throughout tropical India, particularly in Orissa, Bihar and Manipur. The plant is CVS active and used in splenomegaly. Fruits and leaves contain solasonine, solasodine, jurubine, jurubidine, torvonin, torvogenin, chlorogenin, paniculogenin, sisalogenone, neosolaspigenin and solaspigenin.

11. S. trilobatum Linn.

Eng: Climbing Brinjal; San: Alarka;

Mal: Tutavalam;

Tam: Tuduvalai;

Kan: Mullumusta;

Tel: Telavuste

It is mostly seen in South and Western India. The plant contains alkamine and solamarine. The berry and flowers are bechic and used in bronchitis. The alkaloid solamarine is antibiotic and possesses antitumour activity.

12. S. viarum Dunal, syn. S. Khasianum C. B. Clarke

Hin: Kantakari

It is widely distributed in Khasi, Jaintia and Naga hills of Assam and Manipur upto 2000m and in Sikkim, West Bengal, Orissa and in the Niligiris. The plant and berries contain solasonine (which on hydrolysis yields solasodine), solamargine, khasianine, nantigenin, solasodine, diosgenin and saponin-solakhasianin. The plant is spasmolytic and CNS active. The berry is a source of solasodine used in the synthesis of corticosteroidal hormones.

Agrotechnology: The agrotechnology for the solanaceous group of plants are almost similar. They come up very well in tropical and subtropical climate upto 2000m altitude. They can be raised on a variety of soils good in organic matter. Propagation is by seeds. The seedlings are first raised in the nursery and transplanted to the main field 30-45 days after sowing when the plants attain 8-10cm height. During rainy season, planting is done on ridges while during summer in furrows, at a spacing ranging from 30-90cm depending upon the stature and spreading habit of the plant. The transplanted seedlings should be given temporary shade for 2-4 days during summer. FYM or compost at 20-25t/ha is applied at the time of land preparation. A moderate fertiliser dose of 75:40:40 N, P2O5, K2O/ha may be given. P is given as basal dose, N and K are applied in 2-3 split doses. One or two intercultural operations are needed to control weeds. The plants need earthing up after weeding and topdressing. Irrigation is needed at 3-4 days interval during summer and on alternate days during fruiting period. Plants need staking to avoid lodging due to heavy bearing. Shoot borers, mealy bugs, leaf webbers and miners are noted on the crop, which can be controlled by spraying mild insecticides. Root knot nematode, wilting and mosaic diseases are also noted on the crop. Field sanitation, crop rotation and burning of crop residues are recommended.... solanums

Evans, William C. (b.pharm., B.sc., Ph.d., F.r. Pharm. S)

Formerly Reader in Phytochemistry, Department of Pharmacy, University of Nottingham. Research interests: secondary metabolites of the Solanaceae and Erythroxylaceae. Principal author of Trease and Evans’ Pharmacognosy. Visiting lecturer, School of Phytotherapy (Herbal Medicine). ... evans, william c. (b.pharm., b.sc., ph.d., f.r. pharm. s)

Datura Stramonium

Linn.

Synonym: D. tatula Linn.

Family: Solanaceae.

Habitat: The Himalaya from Kashmir to Sikkim up to 2,700 m, hilly districts of Central and South India.English: Thornapple, Jimsonweed, Stramonium.Ayurvedic: Krishnadhattuura, Dhuurta (black seed var.), Unmatta, Kitav, Tuuri, Maatul, Madan.

Unani: Dhaturaa.

Action: Spasmolytic, antiasthmatic, anticholinergic, cerebral depressant, nerve-sedative. Controls spasms of bronchioles in asthma. Anticholinergic. Effects of overdose are similar to those of atropine. Temporary relief from Parkinsonian tremor recorded. (Contraindicated with depressant drugs.) Applied locally, stramonium palliates the pain of muscular rheumatism, neuralgia, also pain due to haemorrhoids, fistula, abscesses and similar inflammations. Prevents motion sickness.

Key application: In diseases of the autonomic nervous system. (Included among unapproved herbs by German Commission E.) The British Herbal Pharmacopoeia reported antispasmodic action of the leaf; Indian Herbal Pharmacopoeia accepted it as expectorant and antispasmodic. Whole plant contains 0.26% alkaloids (seeds 0.98% and stem 0.08%); also flavonoids, withanolides, cou- marins and tannins; the major alkaloid is hyoscyamine (44-67%), hyoscine (13.2-25.3%) and atropine (0.01-0.1%). The tropane alkaloids are similar to those found in Atropa belladonna. Hyoscine is five times as active as atropine in producing mydriasis, but its main use is as antimotion sickness drug; and in combination as a sedative.Toxic constituents include anti- cholinergic alkaloids.

Dosage: Leaf—60-185 mg powder; seed—60-120 mg powder (CCRAS.)

... datura stramonium

Hyoscyamus Muticus

Linn.

Family: Solanaceae.

Habitat: North-western Himalayas. Cultivated on limited scale in North Indian plains.

English: Egyptian Henbane.

Ayurvedic: Paarsika-yavaani (related species), Turushkaa.

Unani: Ajwaayin Khuraasaani, Shuukraan, Tukhm-bang.

Folk: Vajra-bhang.

Action: Sedative.

The leaves and flowering tops contain higher concentration of tropane alkaloids than other species of Hyoscy- amus, used as a source of hyoscine.... hyoscyamus muticus

Lycium Barbarum

Linn.

Family: Solanaceae.

Habitat: Punjab, Rajasthan, Gujarat and Maharashtra.

Unani: Chirchataa, Chirchitaa, Chirchitta.

Folk: Kheechar Chirchataa.

Action: Immunostimulatory, antiproliferatory, antiageing; antioxidant.

The leaves and flowers contain free quercetin (1.28 and 1.58 mg/g dry weight, respectively), and bound kaem- pferol. Total alkaloid percentage is nearly the same in shoots (1.26%) and fruits (1.24%) but lower in cal- li (0.83%) and roots (0.67%). Fruits had highest atropine content (0.95%) and shoots the highest hyoscyamine content (0.33%).

Flavonoids are active against E. coli, Staphylococcus aureus and Candida albicans (quercetin does not show activity against Candida albicans).

The polysaccharide extract from fruits showed antiageing, immunos- timulatory and antiproliferatory activities. The polysaccharide acts as an an- tioxidant and prevented CCl4-induced increases in lipid peroxidases in liver. It can also protect against genetic damage from mutagenic and genotoxic compounds. This activity leads to its potential use in preventing the adverse effects of chemotherapeutic agents.

The fruit contain beta-carotene (8 mg/100 g dry weight), also free amino acids (1.0-2.6%); major amino acid is proline.

The dried fruit and root bark reduce cholesterol level by preventing its absorption in gastrointestinal tract. A constituent of the root bark, kuko- amine exhibits cholesterol lowering, antihypertensive and hypoglycaemic effects. Hepatoprotective activity is attributed to a cerebroside constituent found in the fruit. (Natural Medicines Comprehensive Database, 2007.)

The fruit and root bark is contraindi- cated in bleeding disorders and hypoglycemia. (Sharon M. Herr.)... lycium barbarum

Eggplant

Nutritional Profile Energy value (calories per serving): Low Protein: Moderate Fat: Low Saturated fat: Low Cholesterol: None Carbohydrates: High Fiber: High Sodium: Low Major vitamin contribution: Vitamin C (low) Major mineral contribution: Potassium (low)

About the Nutrients in This Food Eggplant is a high-fiber food with only minimum amounts of vitamins and minerals. One cup (100 g/3.5 ounces) boiled eggplant has 2.5 mg dietary fiber and 1.3 mg vitamin C (2 percent of the R DA for a woman, 1 percent of the R DA for a man). In 1992, food scientists at the Autonomous University of Madrid studying the chemistry of the eggplant discovered that the vegetable’s sugar content rises through the end of the sixth week of growth and then falls dramatically over the next 10 days. The same thing happens with other flavor chemicals in the vegetable and with vitamin C, so the researchers concluded that eggplants taste best and are most nutritious after 42 days of growth. NOTE : Eggplants are members of the nightshade family, Solanacea. Other members of this family are potatoes, tomatoes, and red and green peppers. These plants produce natural neurotoxins (nerve poisons) called glycoalkaloids. It is estimated that an adult would have to eat 4.5 pounds of eggplant at one sitting to get a toxic amount of solanine, the glycoalkaloid in eggplant.

The Most Nutritious Way to Serve This Food The eggplant’s two culinary virtues are its meaty texture and its ability to assume the flavor of sauces in which it is cooked. As a result, it is often used as a vegetarian, no-cholesterol substitute for veal or chicken in Italian cuisine, specifically dishes ala parmigiana and spaghetti sauces. However, in cooking, the egg- plant absorbs very large amounts of oil. To keep eggplant parmigiana low in fat, use non-fat cheese and ration the olive oil.

Buying This Food Look for: Firm, purple to purple-black or umblemished white eggplants that are heavy for their size. Avoid: Withered, soft, bruised, or damaged eggplants. Withered eggplants will be bitter; damaged ones will be dark inside.

Storing This Food Handle eggplants carefully. If you bruise an eggplant, its damaged cells will release polyphe- noloxidase, an enzyme that hastens the oxidation of phenols in the eggplant’s flesh, produc- ing brown compounds that darken the vegetable. Refrigerate fresh eggplant to keep it from losing moisture and wilting.

Preparing This Food Do not slice or peel an eggplant until you are ready to use it, since the polyphenoloxidase in the eggplant will begin to convert phenols to brown compounds as soon as you tear the vegetable’s cells. You can slow this chemical reaction (but not stop it completely) by soaking sliced egg- plant in ice water—which will reduce the eggplant’s already slim supply of water-soluble vita- min C and B vitamins—or by painting the slices with a solution of lemon juice or vinegar. To remove the liquid that can make a cooked eggplant taste bitter, slice the eggplant, salt the slices, pile them on a plate, and put a second plate on top to weight the slices down. Discard the liquid that results.

What Happens When You Cook This Food A fresh eggplant’s cells are full of air that escapes when you heat the vegetable. If you cook an eggplant with oil, the empty cells will soak it up. Eventually, however, the cell walls will collapse and the oil will leak out, which is why eggplant parmigiana often seems to be served in a pool of olive oil. Eggplant should never be cooked in an aluminum pot, which will discolor the eggplant. If you cook the eggplant in its skin, adding lemon juice or vinegar to the dish will turn the skin, which is colored with red anthocyanin pigments, a deeper red-purple. Red anthocyanin pigments get redder in acids and turn bluish in basic (alkaline) solutions. Cooking reduces the eggplant’s supply of water-soluble vitamins, but you can save the Bs if you serve the eggplant with its juices.

Adverse Effects Associated with This Food Nitrate/nitrite reactions. Eggplant—like beets, celery, lettuce, radish, spinach, and collard and turnip greens—contains nitrates that convert naturally into nitrites in your stomach, and then react with the amino acids in proteins to form nitrosamines. Although some nitrosamines are known or suspected carcinogens, this natural chemical conversion presents no known problems for a healthy adult. However, when these nitrate-rich vegetables are cooked and left to stand at room temperature, bacterial enzyme action (and perhaps some enzymes in the plants) convert the nitrates to nitrites at a much faster rate than normal. These higer-nitrite foods may be hazardous for infants; several cases of “spinach poisoning” have been reported among children who ate cooked spinach that had been left standing at room temperature.

Food/Drug Interactions MAO inhibitors. Monoamine oxidase (M AO) inhibitors are drugs used as antidepressants or antihypertensives. They inhibit the action of enzymes that break down tyramine, a natu- ral by-product of protein metabolism, so that it can be eliminated from the body. Tyramine is a pressor amine, a chemical that constricts blood vessels and raises blood pressure. If you eat a food rich in tyramine while you are taking an M AO inhibitor, the pressor amine can- not be eliminated from your body, and the result may be a hypertensive crisis (sustained elevated blood pressure). Eggplants contain small amounts of tyramine. False-positive urine test for carcinoid tumors. Carcinoid tumors (tumors that may arise in tis- sues of the endocrine and gastrointestinal systems) secrete serotonin, which is excreted in urine. The test for these tumors measures the level of serotonin in your urine. Eating egg- plant, which is rich in serotonin, in the 72 hours before a test for a carcinoid tumor might raise the serotonin levels in your urine high enough to cause a false-positive test result. (Other fruits and vegetables rich in serotonin are bananas, tomatoes, plums, pineapple, avo- cados, and walnuts.)... eggplant

Indian Ginseng

Withania somnifera

Solanceae

San: Aswagandha, Varahakarni

Hin: Asgandh, Punir Mal: Amukkuram

Tam: Amukkira

Tel: Vajigandha

Mar: Askandha

Guj: Ghoda

Kan: Viremaddinagaddi

Importance: Indian ginseng or Winter cherry is an erect branching perennial undershrub which is considered to be one of the best rejuvenating agents in Ayurveda. Its roots, leaves and seeds are used in Ayurvedic and Unani medicines, to combat diseases ranging from tuberculosis to arthritis. The pharmacological activity of the plant is attributed to the presence of several alkaloids and withaniols. Roots are prescribed in medicines for hiccup, several female disorders, bronchitis, rheumatism, dropsy, stomach and lung inflammations and skin diseases. Its roots and paste of green leaves are used to relieve joint pains and inflammation. It is also an ingredient of medicaments prescribed for curing disability and sexual weakness in male. Leaves are used in eye diseases. Seeds are diuretic. It is a constituent of the herbal drug ‘Lactare’ which is a galactagogue.

Aswagandha was observed to increase cell-mediated immunity, prevent stress induced changes in adrenal function and enhance protein synthesis. Milk fortified with it increases total proteins and body weight. It is a well known rejuvenating agent capable of imparting long life, youthful vigour and intellectual power. It improves physical strength and is prescribed in all cases of general debility. Aswagandha powder (6-12g) twice a day along with honey and ghee is advised for tuberculosis in Sushruta Samhita. It also provides sound sleep (Prakash, 1997).

Distribution: Aswagandha is believed to have oriental origin. It is found wild in the forests of Mandsaur and Bastar in Mandhya Pradesh, the foot hills of Punjab, Himachal Pradesh, Uttar Pradesh and western Himalayas in India. It is also found wild in the Mediterranean region in North America. In India it is cultivated in Madhya Pradesh, Rajastan and other drier parts of the country.

Botany: Aswagandha belongs to the genus Withania and family Solanaceae. Two species, viz, W. coagulans Dunal and W. somnifera Dunal are found in India. W. coagulans is a rigid grey under shrub of 60-120cm high. W. somnifera is erect, evergreen, tomentose shrub, 30-75cm in height. Roots are stout, fleshy, cylindrical, 1-2cm in diameter and whitish brown in colour. Leaves are simple, ovate, glabrous and opposite. Flowers are bisexual, inconspicuous, greenish or dull yellow in colour born on axillary umbellate cymes, comprising 5 sepals, petals and stamens each; the two celled ovary has a single style and a bilobed stigma. The petals are united and tubular. The stamens are attached to the corolla tube and bear erect anthers which form a close column or cone around the style. Pollen production is poor. The fruit is a small berry, globose, orange red when mature and is enclosed in persistent calyx. The seeds are small, flat, yellow and reniform in shape and very light in weight. The chromosome number 2n = 48.

The cultivated plants have sizable differences from the wild forms not only in their morphological characters but also in the therapeutical action, though the alkaloids present are the same in both (Kaul, 1957). Some botanists, therefore, described the cultivated plant distinct from wild taxa and have coined a new name W. aswagandha (Kaul, 1957) which is contested by Atal and Schwarting (1961).

Agrotechnology: Asgandh is a tropical crop growing well under dry climate. The areas receiving 600 to 750mm rainfall is best suited to this crop. Rainy season crop requires relatively dry season and the roots are fully developed when 1-2 late winter rains are received. Sandy loam or light red soils having a pH of 7.5- 8.0 with good drainage are suitable for its cultivation. It is usually cultivated on poor and marginal soils. Withania is propagated through seeds. It is a late kharif crop and planting is done in August. Seeds are either broadcast-sown or seedlings are raised in nursery and then transplanted. Seed rate is 10-12 kg/ha for broadcasting and 5kg/ha for transplanting. In direct sown crop plants are thinned and gap filling is done 25-30 days after sowing. Seeds should be treated with Dithane M-45 at 3g/kg of seeds before sowing. Seeds are sown in the nursery just before the onset of rainy season and covered with light soil. Seeds germinate in 6-7 days. When seedlings are six weeks old they are transplanted at 60cm in furrows taken 60cm apart. The crop is mainly grown as a rainfed crop on residual fertility and no manure or fertilizers are applied to this crop generally. However, application of organic manure is beneficial for realizing better yields. It is not a fertilizer responsive crop. One hand weeding 25-30 days after sowing helps to control weeds effectively. No serious pest is reported in this crop. Diseases like seedling rot and blight are observed. Seedling mortality becomes serious under high temperature and humid conditions. The disease can be minimized by use of disease free seeds and treatment with thiram or deltan at 3-4g/kg seed before sowing. Further, use of crop rotation, timely sowing and keeping field well drained also protect the crop. Spraying with 0.3% fytolan, dithane Z-78 or dithane M-45 will help controlling the disease incidence. Spraying is repeated at 15 days interval if the disease persists. Aswagandha is a crop of 150-170 days duration. The maturity of the crop is judged by the drying of the leaves and reddening of berries. Harvesting usually starts from January and continues till March. Roots, leaves and seeds are the economical parts. The entire plant is uprooted for roots, which are separated from the aerial parts. The berries are plucked from dried plants and are threshed to obtain the seeds. The yield is 400-500kg of dry roots and 50-75kg seeds per hectare.

Post harvest technology: The roots are separated from the plant by cutting the stem 1-2cm above the crown.

Roots are then cut into small pieces of 7-10cm to facilitate drying. Occasionally, the roots are dried as a whole. The dried roots are cleaned, trimmed, graded, packed and marketed. Roots are carefully hand sorted into the following four grades.

Grade A: Root pieces 7cm long, 1-1.5cm diameter, brittle, solid, and pure white from outside.

Grade B: Root pieces 5cm long, 1cm diameter, brittle, solid and white from outside.

Grade C: Root pieces 3-4cm long, less than 1cm diameter and solid. Lower grade: Root pieces smaller, hollow and yellowish from outside.

Properties and activity: Aswagandha roots contain alkaloids, starch, reducing sugar, hentriacontane, glycosides, dulcital, withaniol acid and a neutral compound. Wide variation (0.13-0.31%) is observed in alkaloid content. Majumdar (1955) isolated 8 amorphous bases such as withanine, somniferine, somniferinine, somnine, withananine, withananinine, pseudowithanine and withasomnine. Other alkaloids reported are nicotine, tropine, pseudotropine, 3, -tigloyloxytropane, choline, cuscudohygrine, anaferine, anahygrine and others. Free aminoacids in the roots include aspartic acid, glycine, tyrosine, alanine, proline, tryptophan, glutamic acid and cystine. Leaves contain 12 withanolides, alkaloids, glycosides, glucose and free amino acids. Berries contain a milk coagulating enzyme, two esterases, free amino acids, fatty oil, essential oil and alkaloids. Methods for alkaloid’s analysis in Asgandh roots have also been reported (Majumdar, 1955; Mishra, 1989; Maheshwari, 1989). Withania roots are astringent, bitter, acrid, somniferous, thermogenic, stimulant, aphrodisiac, diuretic and tonic. Leaf is antibiotic, antitumourous, antihepatotoxic and antiinflammatory. Seed is milk coagulating, hypnotic and diuretic.... indian ginseng

Lycopersicon Esculentum

Mill.

Synonym: Solanum lycopersicum Linn.

Family: Solanaceae.

Habitat: Cultivated in many parts of India.

English: Tomato, Love Apple.

Unani: Tamaatar.

Action: Mild aperient, blood purifier, cholagogue, digestive. Used in homoeopathy for treating rheumatic conditions, colds, chills, digestive disorders, diabetes, obesity, leucorrhoea, metrorrhagia.

Tomato is a powerful deobstruent. It promotes flow of bile; mildly laxative, especially when taken raw. Tomato stimulates torpid liver and kidneys and helps to wash away toxins. Tomato is recommended for diabetics. It is a major dietary source of carotenoid lycopene.

Tomato juice inhibits carcinogenic N-nitrosocompound formation chiefly in the stomach. Most of the inhibition of formation of N-nitrosomorpholine by phenolic fraction of tomato juice was due to chlorogenic acids. The ascorbate fraction of the juice also contains compounds that inhibit ni- trosation.

Consumption of tomato juice can significantly increase serum lycopene levels. (Decreased serum lycopene concentrations are associated with an increase risk of prostate cancer.) (Natural Medicines Comprehensive Database, 2007.)

The alcoholic extract of tomato possesses CNS depressant and analgesic properties.... lycopersicon esculentum

Mandragora Autumnalis

Spreng.

Synonym: M. microcarpa Bertol. M. officinarum Linn.

Family: Solanaceae.

Habitat: Mediterranean region.

English: Mandrake.

Ayurvedic: Wrongly equated with Lakshmanaa, a fertility promoting herb. (In Indian medicine, Panax quinquefolium Linn. and Panax schinseng Nees have been equated with Lakshmanaa.)

Action: Anaesthetic, narcotic, poisonous. Alkaloid pattern similar to Atropa belladona. A sample of roots from Morocco contained atropine (0.2% at flowering stage).

In India, Panax sp. are perceived as fertility and vitality promoting herbs, which have been attributed to Laksh- manaa. Mandrake exhibits anticholinergic effects.

English Mandrake and American Mandrake are equated with Bryonia alba and Podophyllum hexandrum respectively.... mandragora autumnalis

Nicotiana Tabacum

Linn.

Family: Solanaceae.

Habitat: Native to tropical America; cultivated mainly in Andhra Pradesh, Maharashtra, Karnataka, Uttar Pradesh, West Bengal.

English: Tobacco.

Ayurvedic: Taamraparna, Dhuu- mrapatraa.

Unani: Tambaakhu.

Action: Leaves—decoction is locally applied for muscle relaxation in dislocation, strangulated hernia and orchitis. Also for arthralgia, lumbago, rheumatism and gout (an ointment is made by simmering the leaves in lard). Not used internally as a medicine.

The plant contains nicotine as the major alkaloid.

Toxic influence of cigarette and bidi smoking on carboxyhaemoglobin levels of the blood of regular smokers was compared and no significant difference was observed in both of them. A py- rolysed tobacco product, used in India as a dentifrice, when administered to rats, showed activity comparable to benzo(a)pyrene, a potent carcinogen.

Habitual consumption of betel quid containing tobacco shows a strong cy- totoxic potential.

Nicotiana rustica Linn. is known as Kalakatiyaa or Vfilaayati tobacco. Its nicotine content is high and is not suitable for cigarettes, cigars or bidis. Different variants of this tobacco are used for hookah, chewing and snuff.... nicotiana tabacum

Physalis Alkekengi

Linn.

Family: Solanaceae.

Habitat: Native to South-east Europe and Japan; naturalized in many parts of the world; grown in Indian gardens.

English: Strawberry Tomato, Winter Cherry. ( Withania somnifera is also known as Winter Cherry.)

Ayurvedic: Raajaputrikaa.

Unani: Kaaknaj.

Action: Berries—diuretic, antitussive, oxytocic, analgesic, febrifuge; used for urinary disorders, suppression of urine, gout and intermittent fevers.

Berries contain flavonoids, including luteolin-7-glucoside and withas- teroids.... physalis alkekengi

Physalis Angulata

Linn.

Family: Solanaceae.

Habitat: Native to tropical America; cultivated in Indian gardens in Uttar Pradesh and Tamil Nadu; also grows in moist places as a weed.

Action: Plant—diuretic.

salin B and F have been isolated from the ethanolic extract of the whole plant. Both physalin B and F are reported to inhibit the growth of several human leukaemia cell systems.

Aerial parts yielded seco-withano- lides—cleaved steroidal constituents containing physalins. In Taiwan, phy-

Family: Solanaceae.

Habitat: Throughout India, ascending up to 2,300 m.

English: Sun-berry.

Ayurvedic: Tankaari, Parpotikaa, Chirapotikaa.

Siddha/Tamil: Sodakku thakkali.

Action: Berries—diuretic, aperient, alterative. Used for gout and urinary diseases.

Quercetin 3-O-galactoside, isolated from the crude extract of the leaves, is reported to exhibit anti-inflammatory activity comparable to phenylbutazone in carageenan-induced rat paw oedema.

Physalis minima Linn. var indica C. B. Clarke is common weed in irrigated fields and bunds.

The plant contains withasteroids, physalindicanols, withaminimin and withaphysalin, 3-O-glucosides of kaempferol and quercetin, in addition to beta-sitosterol and its glucoside.

The diuretic action of Physalis minima leaves is attributed to the high content of potassium nitrate (8-10%).... physalis angulata

Scopolia Anomala

Airy Shaw.

Synonym: S. lurida Dunal.

Family: Solanaceae.

Habitat: The Himalayas from Kumaon to Sikkim, up to 3,900 m.

English: Scopolia.

Action: Used like belladonna.

Dried leaves contain 0.32% of alkaloids comprising hyoscyamine, hima- line, atropine and scopolamine.

Ripe seeds contain a small amount of atropine but no hyoscyamine. Extracts of leaves, stalks and seeds showed presence of atropine, scopolamine, cusco- hygrine, hellaradine, tropine, scopine. The alkaloid himaline exhibits atropine type activity. Roots (total alkaloid content 1.9-2.8%), in addition, contain hyoscyamine and himaline. The alkaloid content of the root is reported to be 4.64 times more than that of the leaves of Atropa belladonna.

Flavonoids occurring in the leaves and roots are chlorogenic acid, scopo- letin, and scopoline; the leaves, in addition, contain rutin and caffeic acid.

A related species, S. carniolica Jacquin, (rhizome), has been approved by German Commission E, for use in spasm of gastrointestinal tract, bile ducts and urinary tract.

The rhizome ofS. carniolica (Central and Eastern Europe) gave tropane alkaloids, including hyoscine and hyoscy- amine with cuscohygrine, tropine and pseudotropine.

Leaf extract of Indian species (S. anomala) is found to be more active than belladonna infusions.... scopolia anomala

Solanum Albicaule

Kotschy ex Dunal.

Family: Solanaceae.

Habitat: Saurashtra (Gujarat) and Rajasthan.

Ayurvedic: Brihati (related species).

Folk: Narkanta (Rajasthan).

Action: A decoction of the plant is prescribed for the treatment of ulcers.

See S. indicum Linn. contains solamargine and solasodamine. The average alkaloidal content (calculated as solasodine) of leaves collected from Kashmir, is reported to be 0.3% (dry weight basis).... solanum albicaule

Solanum Dulcamara

Linn.

Solanum aviculare Forst. f.

Family: Solanaceae.

Habitat: Introduced to Kashmir for experimental cultivation.

Ayurvedic: Kantakaari (related species).

Action: An important source of solasodine, a nitrogen analogue of diosgenin and one of the starting materials for the synthesis of corticosteroids and other steroidal hormones.

See S. xanthocarpum. The leaves, stems, flowers and green fruits contain the glycoalkaloid, solaso- nine, of which solasodine is the agly- cone. Besides solasonine, the plant

Family: Solanaceae.

Habitat: The temperate Himalayas from Kashmir to Sikkim at altitudes of 1,200-2,400 m.

English: Woody Night Shade, Bittersweet, Bitter Nightshade, Felonwort.

Ayurvedic: Kaakamaachi-vishesha, Valli-kantakaarikaa.

Unani: Mako (red var.).

Action: Twigs and root bark— stimulating, expectorant, hepatic, astringent, antirheumatic, alterative, antifungal. Dried branches— sedative and analgesic. Used for chronic bronchitis, chronic eczema and rheumatism.

Key application: As a supportive therapy for chronic eczema. (German Commission E.)

The plant is rich in alkaloidal glyco- sides. Alpha-, beta-, gamma-solamari- ne were isolated from the fruits. Toma- tidenol I existed in the plant as alpha- and beta-solamarine. Solasodine was obtained in traces as secondary alkaloid; it existed as solasonine and sola- margine. Aerial parts gave alpha-and beta-soladulcine, the glycoalkaloids. The sterols were present in free form and as esters, glucosides and palmitic esters of glucosides.

Beta-solamarine shows significant tumour-inhibiting activity. Steroidal saponins are antifungal; alkaloids are anticholinergic; solasodine exhibit antiphlogistic activity.... solanum dulcamara

Solanum Elaeagnifolium

Cav.

Family: Solanaceae.

Habitat: Native to tropical America; naturalized in India as a weed (met with in cultivated fields and gardens in Coimbatore).

English: White Horse-Nettle.

Action: Plant—used as a poultice for sores and ulcers. The plant is a rich source of the steroidal alkaloid, solasodine. The fruit and leaves contain 3-4% (solasodine 3.2%) and 0.18% total alkaloids. Fruits also contain 0.55% diosgenin.

A related species S. khasianum (Assam, Sikkim, West Bengal, Orissa and the Nilgiris, ascending to an altitude of 1,600 m) is also a good source of solaso- dine. The fruits collected from Nilgiris contain 5.4% solasodine on dry weight basis.... solanum elaeagnifolium

Solanum Erianthum

D. Don.

Synonym: S. verbascifolium auct. non Linn.

Family: Solanaceae.

Habitat: The tropical and subtropical India and the Andamans. Cultivated in South India. (for berries).

Folk: Chundai (Tami Nadu, Kerala); Rasagadimaanu (Andhra Pradesh); Sowdangigida, Kadusinde (Karnataka); Kutri (Maharashtra). Vidaari is a confusing synonym (used by The Wealth of India). (Vidaari is equated with Pureraria tuberosa.)

Action: Roots—a decoction is prescribed for vertigo. Leaves— prescribed for vaginal discharges. Various plant parts are ground with warm water and applied externally to lessen inflammation, burning sensation and pain. The glycoalkaloid, solasonine is present in the leaves and fruits.... solanum erianthum

Solanum Ferox

Linn.

Family: Solanaceae.

Habitat: Throughout warmer parts of India, up to an elevation of 1,500 m.

Ayurvedic: Brihati, Brihatikaa, Mahati, Hinguli, Prasaha, Vartaki, Kaantaa, Kshudra-bhantaki, Simhi, Bana-bhantaa. Kateri (bigger var.)

Unani: Katai Kalaan.

Siddha/Tamil: Mulli, Pappara-mulli, Karimulli.

Folk: Raam-begun (Bengal).

Action: Plant and root—stimulant, digestive, carminative, astringent, expectorant, diaphoretic, anthelmintic. Used for catarrhal affections, asthma, dry cough; dysuria; intestinal worms; colic, flatulence, vomiting. Berries—used in asthma and rheumatism.

Air-dried fruits and leaves contain solanine; 0.30 and 0.43% of total alkaloids respectively.

Dosage: Fruit, root—3-6 g powder; 50-100 ml decoction. (CCRAS.)... solanum ferox

Solanum Indicum

Linn.

Family: Solanaceae.

Habitat: Throughout India in the plains and foot hills.

English: Poison Berry.

Ayurvedic: Brihati, Kshudra- bhantaaki, Kateri (bigger var.).

Unani: Hadaq, Kataai Kalaan.

Siddha: Mullamkatti, Papparamulli (root).

Folk: Barahantaa.

Action: Root—carminative, expectorant; used for colic, dysuria, coughs and catarrhal affections.

A decoction is prescribed in difficult parturition.

The fruits and leaves contain gly- coalkaloid, solasonine; the presence of solanine in roots, leaves and fruits has been reported. Diosgenin is also present in leaves, stems and fruits.

The total alkaloid content of fruit varies from 0.2 to 1.8% (dry weight basis); plants growing in Jammu and Kashmir bear fruits with high alkaloid content (total alkaloid 1.8%).

An alcoholic extract of fruits is active against Staphylococcus aureus and E. coli. The extract of leaves is also active against E. coli.

The bigger var. of Kateri (Indian Nightshade) is also equated with S. an- guivi Lam., synonym S. indicum auct. non L. It contains salasonine, dios- genin, beta-sitosterol, lanosterol, sola- margine, solasodine and tomatidenol. The seed oil contains carpestrol.

Dosage: Root—10-20 g for decoction. (API, Vol. II.)... solanum indicum

Solanum Melongena

Linn.

Family: Solanaceae.

Habitat: Native to India; cultivated throughout India.

English: Eggplant, Brinjal.

Ayurvedic: Bhantaki, Bhantaa, Vaartaaka, Vaartaaku, Vaartaakini, Vrintaaka.

Unani: Baingan.

Siddha/Tamil: Kathirikai.

Folk: Baingan, Bhantaa.

Action: Fruit—recommended in liver complaints and for amenorrhoea. The fruit is reported to stimulate the intrahepatic metabolism of cholesterol, produces a marked drop in blood cholesterol level. Aqueous extract of fruit is reported to inhibit choline esterase activity of human plasma. Root—anti- asthmatic. Leaves—toxic; used mostly externally for the treatment of burns, cold sores and abscesses. Seeds—anticholesterolemic.

Steroidal saponins, melongosides were isolated from seeds; tigogenin, diosgenin were also obtained. Querce- tin, 3-O-rhamnoside and kaempferol- 3-O-rutinoside have been isolated from the leaves. The ethanol extract (80%) showed anti-inflammatory activity in paw oedema and cotton pellet method in rats. Crude extract of fruits showed diuresis and dose-dependent hypotensive response in normotensive rats. Ether-soluble methanolic extract exhibited strong inhibitory activity on lipoxygenase, involved in atherosclerotic processes and platelet aggregation in rats.

Solanum melongena Linn. var. incanum Kuntze, synonym S. coagulans Forsk. is known as Bana-bhantaa (also a synonym of Solanum ferox) and is used as Brihati in Kerala. Air-dried fruits and leaves from coimbatore contain 1.05 and 0.97% of alkaloids respectively. The fruits contain solaso- dine, campesterol and beta-sitosterol. Solamargine, solasodine, ursolic acid and its derivatives exhibited significant cytotoxic effects against human P2C/PRF/5 cells in vitro.... solanum melongena

Solanum Nigrum

Linn.

Synonym: S. rubrum Mill.

Family: Solanaceae.

Habitat: Throughout India, in dry parts, up to an elevation of 2,100 m.

English: Black Nightshade.

Ayurvedic: Kaakamaachi, Kaakaahya, Kaakamaataa, Dhvankshamaachi.

Unani: Mako (smallar var., black var.)

Siddha/Tamil: Manittakkali.

Action: Plant—anti-inflammatory, antispasmodic, sedative, diuretic, laxative, antiseptic; fresh extract is used for inflammatory swellings, enlargement of liver and spleen and in cirrhosis of liver. Berries— antidiarrhoeal, antipyretic. Berries and flowers—prescribed in cough and cold. Leaves— applied hot to swollen testicles; paste used as poultice to gout, rheumatic swellings and skin diseases.

The berries contain steroidal alkaloid glycosides, solasonine, alpha- and beta-solanigrine, alpha-and beta- solamargine; steroidal sapogenins, di- osgenin and tigogenin; solasodine and solasodine.

Solamargine and solasonine are present also in leaves. The total alkaloid content of fruits and leaves are 0.101 and 0.431% respectively.

Dosage: Whole plant—5-10 ml juice. (API, Vol. II.)... solanum nigrum

Solanum Torvum

Sw.

Family: Solanaceae.

Habitat: Throughout tropical parts of India, in waste places.

English: West Indian Turkey Berry.

Ayurvedic: Brihati (White-flowered- var.), Goshtha-vaartaaku.

Siddha/Tamil: Chundai.

Folk: Ran-Baingan, Goth-begun.

Action: Plant—digestive, diuretic, sedative. Leaves—haemostatic. Fruits—useful in liver and spleen enlargement (cooked and eaten as a vegetable); decoction used for cough. Root—used for poulticing cracks in feet.

Unripe fruits and leaves contain the glycoalkaloid, solasonine (0.37% total alkaloids in air-dried fruits of the plant from Khasi and Jaintia hills). Hydrolysis of the neutral glucosidal fraction yields a steroidal sapogenin, chloro- genin, which is rare in Solanum sp.

The fruits gave sitosterol-D-gluco- side.

Extracts of the plant affect the rate and amplitude of respiration, also blood pressure. They also contract isolated ileum of guinea-pig. Leaves contain no vitamin K or derivatives of naphthoquinone; their haemostatic action may be due to the oil or pectins or both.... solanum torvum

Solanum Trilobatum

Linn.

Family: Solanaceae.

Habitat: Deccan Peninsula.

English: Climbing Brinjal.

Ayurvedic: Alarka, Valli- kantakaarikaa, Kantakaari-lataa.

Siddha/Tamil: Toothuvilai.

Action: Berries and flowers—a decoction is used for cough and chronic bronchitis.

The steroidal alkaloid, solasodine, is present in fruit and leaf of the plant (air-dried fruits and leaves from Coim- batore gave 0.96 and 0.36% respectively). A crude glycoalkaloid mixture, isolated from the plant material, contained about 20% beta-solamarine. The plant exhibited antimitotic, antitu- mour, antibacterial and antifungal activities and showed promising results in two cancer test systems—KB cell and sarcoma 180 in mice.... solanum trilobatum

Solanum Xanthocarpum

S. & W.

Synonym: S. surattense Burm.f. S. virginianum Linn. S. maccanni Sant.

Family: Solanaceae.

Habitat: Throughout India.

English: Wild Eggplant, Yellow- Berried Nightshade.

Ayurvedic: Kantakaari, Kan- takaarikaa, Vyaaghri, Nidigdhikaa, Nidigdhaa, Duhsparshaa, Dhaa- vani, Kshudraa, Keteri (Smallar var.), Bhatakataiyaa. Used as Lakshmanaa.

Unani: Kataai Khurd, Hadaq.

Action: Stimulant, expectorant, diuretic, laxative, febrifuge. Used in the treatment of cough, bronchitis, asthma, for dislodging tenacious phlegm; also used against rheumatism, enlargement of liver and spleen, vomiting, difficult urination, bladder stones, skin diseases. Fruit—used as an adjuvant for promoting conception.

Fruits gave solasonine, solamargine, beta-solamargine and solasodine; petals yielded apigenin; stamens gave quercetin diglycoside and sitosterol. The glycoalkaloid content of fruits collected from Jammu and Kashmir is reported to be 3.5% (total alkaloids, 1.1%). The presence of diosgenin in the plant has been reported.

Both glycoalkaloid and fatty acid fractions of the plants extracts cause liberation of histamine from chopped lung tissue. The beneficial effect of the drug on bronchial asthma may be attributed to the depletion of histamine from bronchial and lung tissue.

Dosage: Whole plant—20-30 g for decoction. (API, Vol. I.)... solanum xanthocarpum

Withania Coagulans

Dunal.

Family: Solanaceae.

Habitat: Drier parts of Punjab, Gujarat, Simla and Kumaon.

English: Vegetable Rennet, Indian Cheese-maker.

Unani: Desi Asgandh, Kaaknaj-e- Hindi, Paneer, Paneer-band. Akri (fruit).

Siddha/Tamil: Ammukkura.

Action: Alterative, emetic, diuretic. Ripe fruits—sedative, CNS depressant, antibilious, emetic, antiasth- matic, diuretic, anti-inflammatory; used in chronic liver troubles and strangury. Dried fruits— carminative, depurative; used for dyspepsia, flatulence and strangury. Leaf—alterative, febrifuge. Seeds— anti-inflammatory, emetic, diuretic, emmenagogue.

Though known as Desi Asgandh, the root is not used in Indian medicine. Ashwagandhaa (Bengali) and Ashwa- gandhi (Kannada) are confusing synonyms of W. coagulans. In the market no distinction is made between the berries of W. coagulans and W. somnifera.

The berries contain a milk-coagulating enzyme, esterases, free amino acids, fatty oil, an essential oil and alkaloids. The amino acid composition fairly agrees with that of papain. The essential oil was active against Micro- coccus pyogenes var. aureus and Vibro cholerae; also showed anthelmintic activity.

The withanolides, withacoagin, coagulan and withasomidienone have been isolated from the plant, along with other withanolides and withaferin. 3- beta-hydroxy-2,3- dihydrowithanolide E, isolated from the fruit showed significant hepatoprotective activity and anti-inflammatory activity equal to hydrocortisone. The ethanolic extract of the fruit showed antifungal and that of the leaves and stem antibacterial activity.... withania coagulans

Withania Ashwagandha

Kaul (cultivated var.)

W somnífera (Linn.) Dunal (Chemo- type I, II, III: Israele.) Family: Solanaceae.

Habitat: Throughout the drier and subtropical parts of India.

English: Winter Cherry. (Physalis alkekengi is also known as Winter Cherry.)

Ayurvedic: Ashwagandhaa, Haya- gandhaa, Ashwakanda, Gandharva- gandhaa, Turaga, Turagagandhaa, Turangagandhaa, Vaajigandhaa, Gokarnaa, Vrishaa, Varaahakarni, Varadaa, Balyaa, Vaajikari. (A substitute for Kaakoli and Kshira- kaakoli.) Cultivated var.: Asgandh Naagori. (Indian botanists consider the cultivated plants distinct from the wild ones.)

Unani: Asgandh.

Siddha: Amukkuramkizhangu.

Action: Root—used as an antiinflammatory drug for swellings, tumours, scrofula and rheumatism; and as a sedative and hypnotic in anxiety neurosis. Leaf— anti-inflammatory, hepatopro- tective, antibacterial. Fruits and seeds—diuretic. Withanine— sedative, hypnotic. Withaferin A—major component of biologically active steroids; as effective as hydrocortisone dose for dose. Antibacterial, antitumour, an- tiarthritic, significantly protective against hepatotoxicity in rats.

The root contains several alkaloids, including withanine, withananine, withananinine, pseudo-withanine, somnine, somniferine, somniferinine. The leaves of Indian chemotype contain 12 withanolides, including withaferin A. Steroidal lactones ofwithano- lide series have been isolated.

Withanine is sedative and hypnotic. Withaferin A is antitumour, an- tiarthritic and antibacterial. Anti-inflammatory activity has been attributed to biologically active steroids, of which withaferin A is a major component. The activity is comparable to that of hydrocortisone sodium succinate.

Withaferin A also showed significantly protective effect against CCl4- induced hepatotoxicity in rats. It was as effective as hydrocortisone dose for dose.

The root extract contains an ingredient which has GABA mimetic activity

The free amino acids present in the root include aspartic acid, glycine, tyrosine, alanine, proline, tryptophan, glutamic acid and cystine.

The Ayurvedic Pharmacopoeia ofIn- dia recommends Ashwagandha in im- potency. This claim could not be sustained in a recent experiment and raises a doubt about the equation of classical Ashwagandha with Withania somnifera. A methanolic extract of With- ania somnifera root induced a marked impairment in libido, sexual performance, sexual vigour and penile dysfunction in male rats. (Llayperuma et al, Asian J Androl, 2002, 295-298.)

The total alkaloids of the root exhibited prolonged hypotensive, brady- cardiac and depressant action of the higher cerebral centres in several experimental animals.

A withanolide-free aqueous fraction isolated from the roots of Withania somnifera exhibited antistress activity in a dose-dependent manner in mice. (Phytother Res 2003, 531-6.)

(See also Simon Mills; American Herbal Pharmacopoeia, 2000; Natural Medicines Comprehensive Database, 2007.)

Dosage: Root—3-6 g powder. (API, Vol. I.)... withania ashwagandha

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