Venesection Health Dictionary

Venesection: From 3 Different Sources


The process of withdrawing blood from a vein for blood donation or therapeutic bloodletting.

Regular bloodletting is performed in the treatment of polycythaemia and haemochromatosis.

Health Source: BMA Medical Dictionary
Author: The British Medical Association
Venesection, or blood-letting, may be employed for two purposes. Most commonly, small quantities of blood may be required for analysis, as an aid to diagnosis or control of various diseases. For example, knowledge of the plasma glucose concentration is important in the diagnosis and management of DIABETES MELLITUS, or blood may be required in order to test for infections such as HIV or HEPATITIS. Blood may be obtained by pricking a ?ngertip, or inserting a needle into a vein, depending on the amount required. Controlled bleeding of larger amounts may rarely be used in certain cases of acute heart failure, as a rapid and temporary method of relieving the strain on the heart. It is also used in the treatment of POLYCYTHAEMIA.
Health Source: Medical Dictionary
Author: Health Dictionary

Phlebotomy

A traditional name for the operation of bloodletting by opening a vein. (See VEINS; VENESECTION.)... phlebotomy

Polycythaemia

A rise in the amount of HAEMOGLOBIN in the blood. This may be caused by an excess in the number of ERYTHROCYTES produced in the BONE MARROW or to a fall in the total volume of PLASMA in the circulatory system. It may also be a response to reduced oxygen levels – for example, among people living at high altitudes – or to liver or kidney disease: this type is called secondary polycythaemia.

The disorder may, however, occur for no obvious reason and is then called polycythaemia vera. This type develops mainly in people over 40 and about 400 people develop the disorder every year in the United Kingdom. The blood thickens, the sufferer may develop high blood pressure, ?ushing, headaches, itching and an enlarged spleen. A stroke may occur later in the disease process. Treatment of polycythaemia vera is by regular removal of blood by VENESECTION, sometimes in combination with an anticancer drug. Secondary polycythaemia is treated by remedying the underlying cause.

Polycythaemia rubra vera A disorder in which the red blood cells increase in number along with an increase in the number of white blood cells and platelets. The cause is unknown. Severe cases may require treatment with CYTOTOXIC drugs or RADIOTHERAPY.... polycythaemia

Bleeding

See HAEMORRHAGE; VENESECTION.... bleeding

Blood-letting

See VENESECTION.... blood-letting

Veins

The vessels which return the blood to the heart after it has circulated through the tissues; they are both more numerous and more capacious than the ARTERIES.

Structure While of similar structure to an artery, veins have much thinner walls, with much less muscular tissue. Furthermore, most veins have one-way VALVES to ensure that the blood ?ows in the right direction. These are most numerous in the legs, then the arms, with few in the internal organs.

Chief veins Four pulmonary veins open into the left atrium of the heart, two from each lung. The superior vena cava returns the blood from the head, neck, and arms; while the inferior vena cava returns blood from the legs and abdomen. The large basilic vein that runs up the inner side of the upper arm is the vein usually opened in blood-letting (see VENESECTION). The great saphenous vein is of special interest, because of its liability to become distended or varicose. Within the abdomen, the inferior vena cava receives branches corresponding to several branches of the aorta, its largest branches being the hepatic veins, which return not only the blood that has reached the liver in the hepatic arteries, but also blood which comes from the digestive organs in the PORTAL VEIN to undergo a second capillary circulation in the liver.

There are several connections between the superior and inferior cava, the most important being three azygos veins that lie upon the sides of the spinal column, the veins on the front of the abdomen, and some veins that emerge from the abdomen at the navel and connect the portal system with those of the inferior and superior vena cava. (See also CIRCULATORY SYSTEM OF THE BLOOD.)... veins

Intermittent Claudication

Lameness or spasmodic pain in the legs when walking a certain distance due to deficient blood supply to the muscles. Associated with artery disorders, muscular weakness. The diseased artery cannot carry enough blood to supply the oxygen needs of the muscles.

Treatment. Circulatory stimulants. Vaso-dilators.

Alternatives. BHP (1983) – Prickly Ash bark, Cramp bark, Black Cohosh, Angelica root, Hawthorn, Wild Yam. Prophylactic – Garlic.

Decoction. Mix, equal parts: Black Cohosh, Prickly Ash bark, Hawthorn berries. One teaspoon to each cup of water simmered gently 20 minutes. Half-1 cup thrice daily.

Formula. Hawthorn 2; Black Cohosh 1; Prickly Ash 1. Dose: Powders: 500mg (two 00 capsules or one- third teaspoon). Liquid Extracts: one 5ml teaspoon. Tinctures: two 5ml teaspoons. Thrice daily in water or honey.

Tablets/capsules. Prickly Ash. Hawthorn. Black Cohosh. Garlic, 2 at night. Cramp bark. Ginkgo.

Life Drops. 3-10 drops in cup of tea to relieve spasm.

Ginkgo biloba. “Walking distance is definitely increased.” (Rudolf F. Weiss MD. Herbal Medicine, Beaconsfield Publishers)

Garlic. 80 patients with symptomatic state II occlusive disease (claudication), randomised, to take either Garlic powder 800mg a day in tablet form (equivalent to Kwai) or placebo for 12 weeks. A significantly greater improvement in walking distance, apparent after just 4 weeks, occurred in the Garlic-treated group compared with the placebo group. (Professor H. Kiesewetter, Department of Clinical Haemostasiology, University of Saarland, Germany)

Diet. Lacto-vegetarian.

Supplements. Vitamin E, 400iu morning and evening.

General. Venesection sometimes necessary. No smoking or alcohol. See: BUERGER’S DISEASE, RAYNAUD’S DISEASE, ARTERIOSCLEROSIS, PHLEBITIS, THROMBOSIS. ... intermittent claudication

Haemochromatosis

An inherited disease in which too much dietary iron is absorbed. Excess iron gradually accumulates in the liver, pancreas, heart, testes, and other organs. Men are more frequently affected because women regularly lose iron in menstrual blood.

Loss of sex drive and a reduction in the size of the testes are often the first signs. Excess iron over a period of time causes liver enlargement and cirrhosis, and can lead to diabetes mellitus, bronzed skin coloration, cardiac arrhythmia, and, eventually, liver failure and liver cancer.

Diagnosis is based on blood tests and a liver biopsy. Treatment is by regular venesection. (See also haemosiderosis.)... haemochromatosis

Porphyria

Any of a group of uncommon and usually inherited disorders caused by the accumulation of substances called porphyrins. Sufferers often have a rash or blistering brought on by sunlight, and certain drugs may cause abdominal pain and nervous system disturbances. Porphyrins are formed in the body during the manufacture of haem (a component of haemoglobin). A block in this manufacture causes a build-up of porphyrins. Such blocks are the result of various enzyme deficiencies, which are genetic disorders. Porphyria may also be due to poisoning.

There are 6 types of porphyria. Acute intermittent porphyria usually appears in early adulthood, causing abdominal pain, and often limb cramps, muscle weakness, and psychiatric disturbances. The patient’s urine turns red when left to stand. Barbiturate drugs, phenytoin, oral contraceptives, and tetracyclines precipitate attacks.

Variegate porphyria has similar effects but also causes blistering of sun-exposedskin. Hereditary coproporphyria also has similar effects and may cause additional skin symptoms.

Protoporphyria usually causes skin symptoms after exposure to sunlight, as does porphyria cutanea tarda. In this type, wounds are slow to heal, and urine is sometimes pink or brown. Many cases are precipitated by liver disease.

The rarest and most serious form, congenital erythropoietic porphyria, causes red discoloration of urine and the teeth, excessive hair growth, severe skin blistering and ulceration, and haemolytic anaemia. Death may occur in childhood. Diagnosis is made from abnormal levels of porphyrins in the urine and faeces. Treatment is difficult. Avoiding sunlight and/or precipitating drugs is the most important measure. Acute intermittent porphyria, variegate porphyria, and hereditary coproporphyria may be helped by administration of glucose or haematin. Cases of porphyria cutanea tarda may be helped by venesection.... porphyria




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