Ait.
Habitat: The temperate regions of northern hemisphere; introduced in Jammu and Kashmir for cultivation.
English: American Hellbore, Green Hellebore.Action: Rhizomes and roots— cardiac depressant, hypotensive. (Contraindicated in cardiac disease. Large doses cause bradycardia.) Used in the treatment of convulsions, headache, neuralgia, inflammatory affections of respiratory tract; and as sedative. Formerly used for high blood pressure, especially associated with toxemia of pregnancy.
Ceveratrum-type alkaloids, found as esters, are hypotensive and cause vasodilatation (probably by inhibition of vasomotor centre and stimulation of the vagus). Overdoses cause vomiting. Alkaloids are teratogenic.
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