one of a group of *antimitotic drugs (see also cytotoxic drug) derived from the periwinkle (Vinca rosea). Vinca alkaloids are used especially to treat leukaemias and lymphomas; they include vinblastine, vincristine, and vindesine. Vinorelbine is used in the treatment of advanced breast cancer and *non-small-cell lung cancer. Vinflunine is given by intravenous infusion to treat *transitional cell carcinoma. Vinca alkaloids are highly toxic; side-effects include *myelosuppression, peripheral neuropathy, and severe irritation at the injection site.... vinca alkaloid
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