Habitat: A tree, found in Rajasthan,
Synonym: W arborea (Dennst.) Mabberley.Habitat: Punjab, Rajasthan, Bihar, Assam and Western Peninsula.
Ayurvedic: Kutaja (red-flowered). Indrayava (seeds).Siddha/Tamil: Pala.Action: Two varieties—male and female—are mentioned in Ayurvedic texts. Mostly, Holarrhena is supposed to be the male and Wrightia the female. In Unani medicine, Inderjao Talkh (bitter) is equated with Holarrhena antidysenterica (Conesse Bark) and Inderjao Shireen (sweet) with Wrightia tinctoria (known as Dyer's Oleander, Blue Dyeing Roseberry).
Dried bark is used as a substitute for Holarrhena antidysenterica bark. Alkaloid conessine is the active principle of both the barks.Besides conessine, other alkaloids present in the bark are conessine di- hydrate, holarrhine, kurchicine and a very minute quantity of conkurchine. The bark contains beta-sitosterol, lupe- ol, alpha-amyrin and reducing sugars besides alkaloids.The isoflavone, wrightiadione, isolated from the stem bark, displayed cytotoxic activity. Two aliphatic compounds, n-tritriacont-16-one and hexa- consan-3, 6-diol-12-oic acid, have also been isolated from the bark.See Wrightia tinctoria and Holar- rhena antidysenterica.